### Note: only representative eukaryotes with predicted protein datasets are shown

		#Dictyostelium discoideum AX4
>cobalamin-dependent methionine synthase, XP_638483.1
MINSNDKNESDTFGIIRKILSERIMVLDGAMGTEIQKFKLKDNDYRGEEFKDFPHELGGNNDLLSLTQPHIIREIHCKYLEAGADFIETNTFNGNIFSQADYKMEHLVKRINIESARLAKSACEEYTKKDPSRPRFVCGAVGPTNKTASISPSVERPEARNVLFDELVSGYLEQVEALVEGGIDVILVETVFDSLNCKAALFAIEEFFKTYSPRLPVFVSGTIVDKSGRTLSGQTGEAFYTSVASANLMVFGLNCALGAQEMRPFLQNISKCSECYVSCYPNAGLPNTFGGYDETPEMMAEQIKEFAESGLLNIVGGCCGTSPDHIRAFCNAIEGIAPRAIPTLVPNTTLSGLEPLVFTKELNFVNVGERCNVSGSRRFANLIKANKYEEALSVARQQVEAGAQIIDINMDEGMIDAVAAIQKFLFFIGSEPEISKVPIMLDSSNFDVVEAGLKCVQGKCIVNSISLKVGEELFIKQAKIVKQYGASVVVMAFDENGQATSKEEKVRICYRSYKILTEQVGFYPQDIIFDPNILTIATGLEEHNNYGVEFIEATREIKALMPLTRVSGGVSNLSFSFRGNEPLREAMHSAFLYYAIAAGMDMGIVNAGALPIYDDIPKDLLKLVEDAILNRTNDATEKLLEYAQANNKSEKANVEVEEWRNKPVSERIAHALVKGITTYIIEDTEEARNTLPSSLSVIEGPLMGGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAHLIPFMEEEKRLKRLEKGNDEAAEDEPDNAGVVVLATVKGDVHDIGKNIVGVVLGCNNYKVIDIGVMTPCEKIVEAIIANKADVVGLSGLITPSLDEMIYVASELERLKFKIPLMIGGATTSQIHTAVKISPHYSQPTVHVLDASRSVTVVQSLLDPNNKEVFAEDVSQQYAELREKHYASLKDRKYTSLEKARQHCVKVNWKTIQPVKPTFLGTQVFKEYSLEKLVTKIDWNPFFVTWQLRGKYPNRGYPRIFNDETVGAEAKKLFDDAQTMLKEIVDKKLLNARGVIGFYPANSIDEDIIIYDHNDDETRSKPIATLFGLRQQNEKETDEPYIAIGDYIAPVSSGVKDYIGLFAVSSGFGLEDMVEKYKKENDDYSSIMAKALADRLAEALAEAVHEDVRREHWAYEKDQALSNEDLFKIKYKGIRPAPGYPAQPDHTEMKTIWSLMNVNENTSIELTDHMAMLPGAAVCGVYFSHEHAKYFSVGKITKEQIESYASRKQITKEEAERWLSSILSYDRLPLVK
>methylmalonyl CoA mutase, XP_637192.1
MGGMAKAVTEGLPKRRIEESAASRQARIDSGIETIVGVNKYKLKEEEKLDILSIDNKKVKEAQIERLKRIKATRNSEEAKKCLEALTEAAKTGKGNLLELSINAARARCTVGEISDALEVVYGRYVPTHSLASGAYKSAYGKTNEIDAVIDAVKKFTKEQGRPPRILVAKMGQDGHDRGAKVVASGFSDLGFDVDISPLFSTAKEVAKSAVESDVHVVGVSSLAAGHKTLVPELIDELKKLDASHISVICGGVIPPQDYDFLYQHGVVAIFGPGSRITDCALSVIKEIEKKLSLKK
>ribonucleoside triphosphate reductase, XP_629553.1
MLTIKRLLLNQNLFKSSCNSTGIISINYNSNNKICFFSSSSTLINKTNEILDIEDNNNNNNEISSSPLFLKETIKEFKLKKEFIEKYSKKKAPFGFGVLGEIVYRRSYSRVKEDNTNEQWFETVERVVNGTYNIQRKWIERHGLEWNQNKAQKSAQEMYNRIFEMKFLPPGRGLYSCGSSTTESKGLFAALNNCAFVSTLDIKKNPSKPFIFLMDASMLGVGVGFDTKGENSIIIKGQLPPPPPQQQPQQQQQQHGQNNNIFIVPDSREGWVESVQLLLDSYFLKRNNPIFDYSSIRKKGEPIKGFGGVCCGYEPLKELHDEIRALLNKCIGKPISSTNIVDLMNLIGKCVVSGNVRQAAEIAFGDPNSQEYIDLKNYQINPQRASFGWCSNNSVFAELGMDYSKVCQSILHNGEPGLAWLDNMKAYSRMVPTELDYKDRRAMGGNPCLEQTLESYELCCLVETFPNNHESLEDYLKTLKYAFLYAKTVTLGSTQWPDTNKVLLRNRRIGCSMSGIAQFIHFNGLHQLKDWCVNGFKLLNELDEKYSEWLAIPKSIKRTSIKPSGTVSLLAGATPGMHYPISEYYIRRIRIQKESNLIPPLVEAGYHVEPAFENSTNVVVEIPIHSGKGIRSANSITMWEQLSLASFLQKYWADNQVSCTVSFDPIKEGPQLKHALDYFQYQLKGVSFLPNSSTTTSVYKQMPYEEIDETRYNQIIANLKPVDFQKLNNSPLEPTPDKFCDSSSCTIVSDNSETLNNL

		#Ajellomyces capsulatus NAm1
>NiCoT, 
PWKMYPLGVLFGLGFDTSSEVALLGISSIEATRGTSIWVILIFPFLFTGRITITFVVCPLMRKLLTQRPHPCLAGMCLLDTIDGALMLSLYVQPAENFLPSKSVNSSSATLSTPSSGAGQPLTTSDAATANPSRNPRNPIAFLYYSIVLTSLTVIVATVIGTIQLLTLILNVTEATGRFWNGVEVAGEYYDVIGGSICGCFILVGGLSVLVYPSWRRWVAQRHELQDQNVDGALEE
>Urease, 
QLIRDGHHTVADLMAIGKMMLGRRHVLPSVTSTVHEVFVEGTFPSGTYLVTIHEPISTEDGDLEKALYGSFLPVPSKDIFPDPDPEDYHPLKMPGAVIPVKQSRIMLNEGRKRISLKVTSKGDRPIQVGSHYHFIEVNPHLDFDRLRSYGYRLDIPAGTAIRFEPGDSKTVTLVEIGGNKVIHGGNFLASGKVDLTRADEILERLQKAGFAHTPEPASGITHIDPHSMDRESYMRMFGATTGDLIRLGSTDLWIKVEKDLTSFGDECTFGGGKTLREGMGQASGRCSDDVLDTVITNALIVDWTGIYVADIGIKDGNIVGIGKAGNPDVMDGVYPNMFVGSGTDVISGERNIVTAGGIDTHIHLITPDQVQEALASGVTTMLGGGTGPSTGTNATTCTPGPNHMKNIIQACDGLPINFGITGKGNDCQPQSLREQIRAGAAGLKLHEDWGCTPAAIDTCLSVCDEYDVQCLIHTDTLNESGFVEQSIQAFKGRAIHTYHTEGAGGGHAPDIISAVQFPNVLPSSTNPTRPFTLNTLDEHLDMVMVCHHLSKNIREDVAFAESRIRAETIAAEDVLHDLGAISMISSDSQAMGRCGEVILRTWNTAHKNKLQRGPLEEDRGTGADNFRVKRYISKYTINPAITQGMSHLIGSVEVGKVADLVMWKFSDFGTKPNMVLKSGMIAMAMM

		#Aspergillus fumigatus Af293
>NiCoT, EAA30079.1
MARLKLPHLRLPPPLSYIPRPALHLITLLILINCLVWAGVGITLHYFPKMISPAVLSYTLGLRHALDADHISAIDLMTRRLIASGQRPVAVGTFFSLGHSTVVIITCIVVAATSGALRDRFDGFQRVGGIIGTSVSAAFLIILGVGNGWVLYKLVKRLRVVMKEQRERRRRVEEGEDLRAEEEQEAMNNLQLEGAGFLARVFRRVFAIVDRPWKMYPLGVLFGLGFDTSSEVALLGIASIQAVQGTSIWLILIFPILFTAGMCMLDTTDGALMMALYTSKAFSRDVVAILYYSIVLTGITVVVSAFIGVIQILSLAYNVAEPTGRFWDGVEAIGDHYDVIGGCICGLFVVVGLASVIIYRPWRKKMEDRMDAMSILDVESPVASPAAVADGAMSPYADSPVVTPLERVPERIV
>Urease, XP_750204.1
MHLIPKEVRDRDLLPTTYIHIHIHSKVSTNHFAPAAGQARHLAIGISRPASSCARCAAQSCRGSGMDFPLFSLRDPLRRLIEANSRPGSHLVESARGIFPTSELEAGYHGAYSQQLIRDGHYSVADLMSIGKTMLGRRHVLPSVVHTLVELQVEGTFPTGTYLVTVHHPISSDDGDLEKALYGSFLPIPPADTFPDPNPDDYLPEKMPGAVLPVKNERITLNDGRKRIRLKVMSKGDRPIQVGSHYHFIETNPQLHFDRLRAYGYRLDIPAGTSVRFEPGDTKTVTLVEIAGNRIIKGGNSIASGKVDISRAEEILQRLQVEGFAHVPEPAPTADSALIAPFTMDREAYARMFGPTTGDLVRLGLTNLWVRVEKDCTVYGDECAFGGGKTLREGMGQSSERSATECLDTVITNALIIDWSGIYKADIGIKNGLISAIGKAGNPDMMDGVHPDMIVGSSTDVIAGENKIVTAGGFDTHIHFICPQQVDEALASGITTFLGGGTGPSTGTNATTCTPGPTLMRQMIQACDGLPINVGITGKGNDSGGKSIEEQIRAGAAGLKLHEDWGSTPAAIDTCLDMCDKFDVQCMIHTDTLNESGFVEQTVKSFKNRTIHTYHTEGAGGGHAPDIISVVEHPNVLPSSTNPTRPFTMNTLDEHLDMLMVCHHLSKNIPEDVAFAESRIRAETIAAEDVLHDLGAISMMSSDSQAMGRCGEVILRTWNTAHKNKAQRGPLKEDEGTGADNFRVKRYISKYTINPAIAQGMSHLIGSVEVGKLADLVIWHPSTFGTKPAQVLKSGMIVASQMGDPNGSIPTIEPVVMRRQFGAFVPSTSIMWVSQASIDDGIVQSYGLKKRIEAVRNCRNIGKKDMKFNDVMPKMRVDPESYVVEADGVLCDAEPAEALPLTQDYFVY

		#Aspergillus nidulans FGSC A4
>NiCoT, EAA58090.1
MSTRPPADSPFIESDLDDKKWTAKSLIRHAERSHSRLPGIRKVPLRSIAVILLVAFVNVVVWVAVAIVLAIDLMTRRLLATGQRPVTVGTFFSLGHSTIVIITSIVVAATAAAVSSRFDKFSTIGGIIGTSVSAAFLILLGFMNAYILYKLYKQMQKVLNLPEGQEDEAWKIEGGGVLFRVLKRAFKLIDRFLLLSPGETIEVTNHSFAAGMCLLDTTDGALMLALYVQPATNFLPPKRTDSTTSQSPLMSAELTPDAASTLDDPITTPQNHRDPVAFLYYSIVLTTLTVIVAIIIGIIQLLTLILNVAEPTGRFWDGVQTAGDYYDVIGGGICGAFLVFGILSVFVYKPWRRWIGKRYGKDAASAGDEEGAYRGEDTGTDAGTSIPRVDTPLNEGGSSVTYGSVHVQPKGNTK
>Urease, EAA66530.1
MPKNDSKTVTIDVEEFTKTRDSFLAKLAQLQSLTFELSRAYINHTSAVLGQDNANVDISAITNTLAASLRDTGVLAAAGTGSGAESGEKKKRKRRADPNAPKRTLTPFFLYMHHNRARIAEELGPDAKPKDVSNEGTRRWAEMPDSQKEVWKKLYADNLAAYREKVAAYKAGLPFDRDDNDKAADQLHLDVAAAEASDEEEEEEEDEHGEEEEEEEEESPEPAKEPTPPPPKRRRSEGKPSKDVSSPVVEKKGRNESPEKKRRGAAKKDKEEPRKSLGGESKRSKKKRKSDYIPIREENWFASQLTILARRPFYFKYIPDIIKGRIHRQAWQYAPYSEGSFLAQRRLARGVRLNHAEAAALISSNLHELIRDGQYSVADLMSIGKTMLGRRHVLPSVPSTLVELQVEGTFTTGSYLVTVHHPISSDDGDLEKALYGSFLPIPPADTFPDPDPEDYLPEKVPGAVIPVKNARITLSEGRKRIKLKVMSKGDRPIQVGSHYHFIEANPQLHFDRFRAYGYRLDIPAGTSVRFEPGDTKTVTLVEIGGHRIIKGGNSLASGPVDLRRADDIIQRLQTAGFAHVPEPAADNALVAPFTIDREAYARLFGPTTGDLIRLGLTNLWVKIEKDYTHYGDECSFGGGKSIREGMGQASGKSHKDCLDTVITNAVIIDWSGIYKADIGIKNGTIVGIGKSGNPDVMDGVHPDMIIGSSTDVIAGENKIVTAGGFDTHIHFICPQQAQEALASGITTFLGGGTGPSTGTNATTCTPGPTHMRQMIQACDQIPINVGITGKGNDSGGIGIEEQIIAGAAGLKLHEDWGSTPAAIDTCLDICEKYDVQCMIHTDTLNESGFVEQTIQAFKNRTIHTYHTEGAGGGHAPDIISVVEHPNVLPSSTNPTRPFTMNTLDEHLDMLMVCHHLSKNIPEDVAFAESRIRAETIAAEDVLHDLGAISMMSSDSQAMGRCGEVILRTWNTAHKNKEQRGQLPEDENTGADNFRVKRYISKYTINPAIAQGMSHLIGSVEVGKLADLVIWSPSYFGTKPSQVLKSGMIVASMMGDPNGSIPTIQPVIMRPQFGAYLPSTSVMFVSQASLDTNTVQSYGLKKRVEAVKNCRNIGKADMKFNDTMPKMKVDPESYRVEADGRLCDAQPAETLPLTQDYFVY

		#Aspergillus terreus NIH2624
>NiCoT, XP_001218345.1
MRTSATVVESPVQNDVPNDVASKGRWSPKGLLRHAERSHSRMPGIRKIPLRAIAVILFVALINVVVWIAAAIVLAIDLMTRRLLATGQRPVTVGTFFSLGHSTIVIITSIVVAATAAAVSSRFDSFSTVGGIIGTSVSAAFLILLGIMNAYILYKLYKQMQKVLNLPEGQEDEAWKIEGGGVLFSILKRMFKLIDRPWKMYPLGILFGLGFDTSSEIALLGISSIEAARGTDFWVILIFPILFTAGMCLLDTTDGALMLSLYIQPATNFLPPKADSEAVPETPLIGTDHEMEPPKNHRDPIAFLYYSIVLTCLTVIVAIVIGIIQVLTLVLNVANPTGRFWDGVQTAGDYYDAIGGGIFYKPWRRWVARRHGKSLPEETEDPNMRPDTPMLADQASDYGAYPSRHSYHTTHPGATCRNNSCPAVFVLPTHLALEELHQIEEQLVQHHARLTYDISEAQLILGKIAHKKRAALELRSRGLWTEEIPLQGATSEPPSKRRRIHGETQARVEEVDLSTETEGEEDGVRSKHDSRRHLKKPQSAVGLPDAADTISVAKLEWFTQCLSSNALLPIDSYIVYQARKTARPPPPPSVSASSDILQRAKQDAAARRADSSAPSSSQRPPPKLYRQTTSENDEAAPLPPAPAWVRNHIVYACQRSAPLHPPNEGFIEQLQAIRQIRELTLDEVGVRAYSTSIAAIAAYPYEFRRPSEVLTLPGCDAKIAHLLAEYQASETRTLAAAKALTTDPELRVLHEFSQIWGVGPKTAREFYYARGWRDLDDIVEHGWAGLSRVQQIGVKYYDEFRRGIPRGEVEAIARVVHRHANAVRPEAAYDGRGVECILVGGYRRGKEISGDVDLILTHRDETVTRNLVVDVVGSLEAEGWVTHTLALNLTTSARDQQPLPFRGESTGAHHFDSLDKALVVWQDPRFDDPQVEEGKGKGKAEEEAARRKRNPNPHRRVDIIISPWRTVGCAVLGWSGDTTFERDLRRYAKKMHGWKFDSSGVRERTTGGRVVDLESEGLTWEERERLVMEGLGVGWREPGERCSR
>Urease, XP_001212926.1
MPPITKPFFAFFFFAILVLATLMQLQAAVAEVSKAYINHSNTVLRGSSDLEDGPLANIANLLQENGLFGFPGFGGARATSPGAKSEVGEVGGKKKRKRAPHDPNAPKRALTPFFLYMQHNRAKISAELGSGARPKEVSDEGTRRWQTMPQAERDVWKQMYAENLALYKERMRLYKAGLPITDDARAANQLQQEAEATNAEESDETGDDDLAAEPPREPTPPRSGKRRRSEVKSTPKQAETPKIPAPEAKTPAEKKASPEKKASPEKRKRGPKAAAAAQKDEASTPAAAGRKSLGGGEAPKETTKRAKKKRLYYGVMKSGVISPPAANQRPNGPYQLISAVWPTNPPSFLFSLLIPVAGPLAVVCGVRRLLLLLLLPSLSLSLFRFRRLLRFFFSSSPLLLEPQPCRVRGDIWFLATFLPQDRTLYLTRLDKLAISQLGFLAQRRLARGVRLNHAEAVALISSNLQELIRDGHYSVADLMSIGKTMLGRRHVLPSVPFTLIELQVEGTFPTGTYLVTVHHPISSDDGDLEKALYGSFLPVPPSDAFPDPKPEDYELEKMPGAVIPVKNERITLNAGRKRIKLKVMSKGDRPIQVGSHYHFIETNPQLHFDRLRAYGYRLDIPAGTSVRFEPGDTKTVTLVEIAGNRVIKGGNFIASGKVDLARAEEIMQRLQVEGFAHTPDPTADAALVEPFTMDREIYARMFGPTTGDLVRLGLTNLWVRVEKDYTMYGDECSFGGGKSLRDGMAQASGRSSKDCLDTVVTNALIIDWTGIYKADIGIRNGVIVGIGKAGNPDIMDGVHPDMVVGSSTDVIAGENKIVTAGGFDTHIHFICPQQVDEALASGITSMLGGGTGPSTGTNATTCTPGPTHMRQMIQATDHLPVNIGITGKGNDCEGLSIEEQIHAGAAGLKLHEDWGSTPAAIDSCLQMCDKYDVQCMIHTDTLNESGFVEQTIQAFKNRTIHTYHTEGAGGGHAPDIIRVVEHANVLPSSTNPTRPFTMNTLDEHLDMLMVCHHLSKNIAEDVAFAESRIRAETIAAEDVLHDLGAISMMSSDSQAMGRCGEVILRTWNTAHKNKEQRGPLPEDEGTGADNFRVKRYISKYTINPAIAQGMAHLIGSIEVGKVADLVIWHPSSFGTKPTQVLKSGTIVAAQMVFHTTFLALYLNTWLTLLTG

		#Neurospora crassa OR74A
>NiCoT, EAA30079.1
MARLKLPHLRLPPPLSYIPRPALHLITLLILINCLVWAGVGITLHYFPKMISPAVLSYTLGLRHALDADHISAIDLMTRRLIASGQRPVAVGTFFSLGHSTVVIITCIVVAATSGALRDRFDGFQRVGGIIGTSVSAAFLIILGVGNGWVLYKLVKRLRVVMKEQRERRRRVEEGEDLRAEEEQEAMNNLQLEGAGFLARVFRRVFAIVDRPWKMYPLGVLFGLGFDTSSEVALLGIASIQAVQGTSIWLILIFPILFTAGMCMLDTTDGALMMALYTSKAFSRDVVAILYYSIVLTGITVVVSAFIGVIQILSLAYNVAEPTGRFWDGVEAIGDHYDVIGGCICGLFVVVGLASVIIYRPWRKKMEDRMDAMSILDVESPVASPAAVADGAMSPYADSPVVTPLERVPERIV
>Urease, EAA35750.1
MHLIPKELDKLAISQLGFLAQRRLARGIKLNHSEATALIANNLQELIRDGNHTVADLMALGATMLGRRHVLPEVTSTLHEIQVEGTFPSGTYLVTVHNPISSDDGDLARALYGSFLPIPPNDDSVFPLPPAAAYEASKQPGAVVCVKEAKVKLNEGRKRIRLRVTSKGDRPIQVGSHYHFIETNPQLEFDRARAYGYRLDIPAGTSVRFEPGDTKTVTLVEIGGNKVIRGGNNLASGKLDLTRAEEIIAKLQKAGFAHAPEEPVGDAAAFISEPFTMDRRAYAVMFGPTVGDMVRLGATDLWIKVEKDYTVYGDECKFGGGKTLREGMGQATGRSDEETLDMVVTNALVVDWTGIYKADIGVKAGVIVGIGKAGNPDVMDGVTPGMIVGSCTDVVAGEGKIITAGGIDTHIHFICPQQAAEALAAGITTFLGGGTGPSAGTNATTCTPGAHYMRQMLQACDSLPLNIGITGKGNDSSPSALREQILAGACGLKLHEDWGTTPAAIDSCLTVCDELDVQCLIHTDTLNESGFVESTIAAFAGRTIHTYHTEGAGGGHAPDIISVVEHPNVLPSSTNPTRPFTRNTLDEHLDMLMVCHHLSKNIPEDVAFAESRIRAETIAAEDVLHDLGAISMMSSDSQAMGRCGEVILRTWNTAHKNKLQRGPLPEDQGTGGADNHRVKRYISKYTINPALAQGMSHLIGSIEPGKLADLVVWDPAWFGTKPSLVIKSGLIASAMMGDPNASIPTVQPVIARPMFAPMVAKSKVLFVSQASLDSGAIEGYGLKSRVEAVKGCRTVGKKDMKFNERMPRMKVDPERYTVEADGEVCTAEPSSELPLTQSYFVY

		#Schizosaccharomyces pombe 972h
>NiCoT, NP_587676.2
MSEYVKPRKNEFLRKFENFYFEIPFLSKLPPKVSVPIFSLISVNIVVWIVAAIVISLVNRSLFLSVLLSWTLGLRHALDADHITAIDNLTRRLLSTDKPMSTVGTWFSIGHSTVVLITCIVVAATSSKFADRWNNFQTIGGIIGTSVSMGLLLLLAIGNTVLLVRLSYWLWMYRKSGVTKDEGVTGFLARKMQRLFRLVDSPWKIYVLGFVFGLGFDTSTEVSLLGIATLQALKGTSIWAILLFPIVFLVGMCLVDTTDGALMYYAYSYSSGETNPYFSRLYYSIILTFVSVIAAFTIGIIQMLMLIISVHPMESTFWNGLNRLSDNYEIVGGCICGAFVLAGLFGISMHNYFKKKFTPPVQVGNDREDEVLEKNKELENVSKNSISVQISESEKVSYDTVDSKV
>Urease, NP_594813.1
MQPRELHKLTLHQLGSLAQKRLCRGVKLNKLEATSLIASQIQEYVRDGNHSVADLMSLGKDMLGKRHVQPNVVHLLHEIMIEATFPDGTYLITIHDPICTTDGNLEHALYGSFLPTPSQELFPLEEEKLYAPENSPGFVEVLEGEIELLPNLPRTPIEVRNMGDRPIQVGSHYHFIETNEKLCFDRSKAYGKRLDIPSGTAIRFEPGVMKIVNLIPIGGAKLIQGGNSLSKGVFDDSRTREIVDNLMKQGFMHQPESPLNMPLQSARPFVVPRKLYAVMYGPTTNDKIRLGDTNLIVRVEKDFTEYGNESVFGGGKVIRDGTGQSSSKSMDECLDTVITNAVIIDHTGIYKADIGIKNGYIVGIGKAGNPDTMDNIGENMVIGSSTDVISAENKIVTYGGMDSHVHFICPQQIEEALASGITTMYGGGTGPSTGTNATTCTPNKDLIRSMLRSTDSYPMNIGLTGKGNDSGSSSLKEQIEAGCSGLKLHEDWGSTPAAIDSCLSVCDEYDVQCLIHTDTLNESSFVEGTFKAFKNRTIHTYHVEGAGGGHAPDIISLVQNPNILPSSTNPTRPFTTNTLDEELDMLMVCHHLSRNVPEDVAFAESRIRAETIAAEDILQDLGAISMISSDSQAMGRCGEVISRTWKTAHKNKLQRGALPEDEGSGVDNFRVKRYVSKYTINPAITHGISHIVGSVEIGKFADLVLWDFADFGARPSMVLKGGMIALASMGDPNGSIPTVSPLMSWQMFGAHDPERSIAFVSKASITSGVIESYGLHKRVEAVKSTRNIGKKDMVYNSYMPKMTVDPEAYTVTADGKVMECEPVDKLPLSQSYFIF

		#Schizosaccharomyces japonicus yFS275
>NiCoT, 
YEKIPLLCKVPRKVSIPIVCLVIWNIAAWIVVSVILATTSSRLFASIILAWTYGLRHALDADHITAIDNLTRRLLGSEKPLSTVGTWFSLGHSTVVTITCLVVAITASKFADKWDNFEKVGGVIGTSVSMAFLFLLAIGNSVLLVRLYIRLRRYCRTGVESDHGASGFWMQHLSKVFQLVDRPWKIYILGFVFGLGFDTSSEIALLGIASLQAISGVSIWLILLFPLIFLSGMCLVDTIDGALMYYAYSSSVSAKNGYFTRCYYSFVLTVISVIAAYTIGVIQMLSLIENVGDKHGSFWDLLDSVSGHYEIVGASICGLFVLGGLLSICLHDWIKNKY
>Urease, 
MQPRELNKLLLHQLGSLAQKRLCRGVKLNKLEATSLIASQIQEFIRDGRHTVAELMDIGRQMLGRRHVQPYVVSSLHEIMIEATFPDGSYLVTIHQPICSDDGNLENALYGSFLPVPDNSLFAMEEEALYSPESAPGYVEVMEGDIVLSRDLPRINLTVSNLGDRPIQVGSHYHFIETNPYLQFDRKKAYGKRLDIPSGTAIRFEPGATKRVTLVPISGHRIIKGGNALASGPVDPSRIDEIMENVSKEGFLHKPEADSPTATPPKPFTIPRQLYATMYGPTRGDIVRLGDTALRVCIEHDFTDYGNESVFGGGKVIRDGMGQASGKSASECLSTVLTNAVVIDSTGIYKADIGIKDGFIVGIGKAGNPDTMDDISPNMTIGSATDVISAENKIVTYGGMDSHVHFICPQQAEEALASGITTMYGGGTGPSTGTNATTCTPNADLARAMFQATDTLPVNIGLTGKGNDSGHRSLREQIEAGMSGMKLHEDWGATPAAIDSCLKICDEYDVQCLIHTDTLNESSFVEGTAKAFKGRTIHTYHVEGAGGGHAPDIISLVQNPNVLPSSTNPTRPFTCNTLDEHLDMLMVCHHLSKNIPEDVAFAESRIRAETIAAEDVLHDLGAISMISSDSQAMGRCGEVISRTWKTAHKNKIQRGFLPEDEGTGVDNFRVKRYISKYTINPAIAHGMSEIIGSVEVGKFADLVLWDFADFGARPNMIIKGGVIAMAAMGDPNASIPTVSPIQTLKMFGALAPQASIVFASKHSVENGVMDTYGLKKRVYPVSSTRNIGKKDMVYNTYQPSMHVDPESYIVKADNKLMTAEPSKTLPLTQGYFYF

		#Ustilago maydis 521
>NiCoT, EAK81763.1
MWRWRPSKRPTLLLRCILLIAAEIAVNALLWVVAAIVFRHRTRFLTLSLLAWTLGLRHALDADHISVIDNATRRIVSLSYSTGSPEARTVRPRRPVTCGLWFSLGHSTIVIAVICAIAISLGIVDRLGKISSVGGIVGAAVSGSTLFLFAIINSILLFQSIKATRRYRAQSREQHEARQVQDLDKTVSDTEAANKQADQPDQVQDHRFKGIFTRLAYPLFRLVDRPYKLYPVGILFGLGFDTASSIALLGIAGATNTQVQDTSLESDQAILPDNATTRSDATIILLALLFTAGMTLVDSLDSVLMINAYAPGELLAPANKAADGSTATRFAWLGRLRFLEDASAPVSKHRSLQDSSLPSAADEQDNKIDTPGYGKQDSDDAGDAGLNADLAHSDRGTSSTLSHLLTLLSILLAFAISIITLMGLIGENCDRCARAAAKQDETHDGGLEGRWWLFWQQANDASGIIGACIVGGFAAILIAWYAGKAILRRYRCTRTA
>Urease, EAK86929.1
MHLLPRERDKLLLHHAGSLAQKRLARGVRLNQTEATALIATVLQERIRDGEHSVAELMQHGKTLLGRCHVLPGVPELLHEVMVEGTFSDGSFLVTVHQPVCTETGDIQAALYSSFYPAPDVSVFLAQMQAETKALVGKAAAEEVLPGALVTKRGAQPIQLCPKRKRVAVKVTNTGDRPIQVGSHYPFLETNAALSFPRMLALGKRLDIAAGTAIRFEPGDSKTVTLVQVGGTKILAGGNNLAAGPLDEFLATSESQVALVKRIEAAGFANEPLPDMEDDSIPAPAPCELSRDAYASLYGPTVGDKVRLADSPLWLEVEKDFTVYGDELKFGGGKVLRDGMGQASGRADSAVLDIVIINALIVDWWGIVKADIGIRNGHIVAIGKAGNPAIMDGVDPNLVVGSCTEVIAGEKFIVTAGAIDAHVHYICPDLHEEALATGITTLIGGGTGPTAGSSATTCTPGQDQLRNMMIATDNVPLNFAFTGKGNDSGLAGLEDQIRAGCAGMKIHEDWGATPAVIDACLTACDKYDVQCNIHTDTLNESCFVEGTLAAFKGRTIHTYHSEGAGGGHAPDIIRVCGETNVLPSSTNPTRPYAKNTLDEHLDMLMVCHHLSKDIVEDVAFADSRIRAETVAAEDVLQDSGAISMISSDSQAMGRIGEVVSRTWRTASKMASLVGPLHEPGSDPQTKGVPHPSEAVSDNLRIKRYVAKYTINPALVHGCSHLIGSIEPGKLADLVFYLPSKFGICPEFVLKGGQVAWAQMGDANASIPTVQPIYGRPMHGSNTNAASHNSVLFVSQISVDQGTVRGYGVNKRIEGVKGCRTVSKKDMKLNTHTPDLKVDPETYEVTDGGRLLTVPPADELPLTQSLHLF

		#Cryptococcus neoformans var. neoformans JEC21
>NiCoT, XP_568832.1
MPAVPISPTTIIWERNSGSLLFFFSLLYSALLKRTYPIPLQTVSIVQFIAKRVNESRLAQRKLTLLGRAIALVAGELLFNAVCWIAAGICFGKTDGILGLALLAWTIGLRHGLDADHISAIDNATRQLVSQGQLPITCGLFFSLGHSTIVIVVNVAIAVSVDIYDKLDRVGSIGGIVGASVSASFLFLIACLNIYFLIGAIKQRRSMKRRQALGLPPDEDEGDPSKIYGGGCMVRVVGPILRAVDRPWKMYPVGVLFGFGFDTASSIALLAISAIAQRGPNGDSISHGKIVILPFLFTAGMSLVDSLDSILMLYAYATPDTTSPEGKLALLQYPDLDHKDSYLEETVATALPAEGGQTERHVIEQTDIPQGEIERLETEDNIKAKTGNEILVEEERVGGPSRVDNNGGVRNERVIKAKANTMSSLSIILTLLSILVALSISLIEIMGLIGDNCTQCQDAANDPDGGGLAGSWWRAWARANDQSGYIGAAIVGCFAAILVGWYGARWGMKKWKARRDANAAILLEDNEDDVTQTPVA
>Urease, XP_572365.1
MHLLPRETDKLIVTTLGTLAQRRLARGLILNRAETIALISSQLQEFIRDGRHSVAELMDLGKKMLGRRHVRKGVPESIHTIQVEGTFPDGVFLVTVDDPISSDDGDLNNAFYGSFLPIPSADVFPAAPEPADTLLGALICRKEPIKINASRRRFKLEVKNAGDRPIQVGSHYHFLETNPALIFDRLLSYGYHLDIPAGTAVRFEPGEKKTVTMVEFGGKKIFHGGSGLASGSFDENLRETKVKEMVEKGGFGHKDQEKVEEGPTTEMNREVYASMFGPTTGDKIKLADMDLWIEVEKDYTVYGEECKFGGGKVLRDGGGQASGRHEHEVLDLVITNALIVDWNGIYKADIGVKNGIIVGIGKAGNPDMMDGVTDGMIVGSSTEVIAGEKLIITAGALDVHVHYICPQLMTEALASGITTVVGGGTGPADGSNATTCTSSSFYMQNMIKATDTVPLNFGFTGKGNDSGTNALRDVIEAGACGLKVHEDWGATPEVIDRALSIADEYDVQVNLHSDTLNESGYVESTLAAIKGRTIHSYHTEGAGGGHAPDIIVVCEYENVLPSSTNPTRPYAVNTLDEHLDMLMVCHHLDKSIPEDIAFADSRIRSETVAAEDVLQDTGAISMISSDCQAMGRIGEVITRTWRTAAKMKQFRGPLEGDEPTRDNNRVKRYVAKYTINPAITHGMSHLIGQVAVGCLADLVFWTAESFGARPEMILKGGVIAWAAMGDANASIPTVQPVIGRPMWGSQPEAAALNSIVWVSQASLDKDLVKRFNIKKRAEAVKNCRAIGKKDMKWNDSMPKMTVDPETYDVHADGVLCDVPPADKLPLTKRYFVY

		#Coprinopsis cinerea okayama7#130
>NiCoT, EAU86074.1
MGQLPVTCGLYFSLGHSTIVFVVTIAIAISVDVFNRLDSVSNVGGIIGPAVSGSFLFIVGLANSIILWRILRRRRKVRNVYDVRLTQTEPGFQQKQQEQRNEEALEEVEGLHDSRKSEGMLMMRILGPVVNFVNRPWKMYPVGVLFGFGFDTASSIALISVSAIAKKQSEYGSFPSSYIIILPLLFTAGMVLLDSADSIIMLYSYTGFPERTWKLVTRKPAARAPAPAIPPPDAKEFSSKKSGVPETEKVVPTAEVLPVELDPSVGTALAVKTNVMSGLSIILTVLSIILAFR
>Urease, EAU85273.1
MRILPREVDKLLLHQVGFLAQQRLARGLRLNQTEAVGLIASQIQERIRDGTYSVAELMQLGKTLLGRRHVLPSVPALLHQIQVEGTFPDGVFLVTIHDPICTEDGDLEAALQGSFLPVPSNDIFPVLDESEYAPEKLPGAIIAKEGRIAINSGRRRIQLRVVNKGDRPIQVGSHYHFIETNPTLSFDRARAYGMRLDIPAGTAVRFEPGDVNVKTVTLVEIAGKRIITGGNGLATGVVDPARTEEVVKGLVQRGFNHVDEPDAPEVKEATDMSREEYISMFGPTAGDRVRLGDTNLWVEVEWDATVYGDEVKFGGAEGQETGKTIREGMGQGTGVSAVDALDLVITNALIIDWSGIYKADIGVKDGVIVGIGKAGNPDVMANVDPNLLIGSSTEVIAGEKLIVTAGALDVHVHYICPQQVEEALASGTTTMIGGGTGPSAGSNATTCTSSPFYMRHMLAATDGLPMNFAFTGKGNDASPTALEEVVRAGAAGFKLHEDWGSTPVVISNCLDVADKYDVQVNIHTDTLNESGFVESTIAAFGGRTIHTYHTEGAGGGHAPDIIVVCGLENVLPSSTNPTRPYTHNTLDEHLDMLMVCHHLDKSIPEDLAFAESRIRGETVAAEDVLHDIGAISMISSDSQAMGRVGEVVSRTWRTASKLKEFRGPLTSLGDTAEKDNGRVKRYIAKYTINPHLVGHVAVGTLADLVLWKPENFGAKPEMVLKSGVIAWSQIGDANASIPSVQPFYGKPMWGAQAGSAAMNSVAFVSELSITSGTIASYGLKKRVEAVRGCRKVTKKDMKWNDLTPTMTVDPENYEVKADGEMMDIEPANTLPLTKAYNLF

		#Bos taurus
>methylmalonyl Coenzyme A mutase, NP_776364.2
MLRAKTRLFLLSPNHLRQLKGSSGSRLIWQRLLHQQQPLHPEWAALAKKQLKGKNPEELIWHTPEGISIKPLYSSRDTKDFPEELPGMKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAKHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIIRTTIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDIYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEESVDVLAIDNTSVRNKQIEKLKKVKSSRDQALAERCLDALTACAASGDGNILALAVDATRARCTVGEITYAMKKVFGEHKANDRMVSGAYRQEFGESKEIAFAIKRVEKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHTVGVSTLAAGHKTLVPELIKELNALGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSI
>5-methyltetrahydrofolate-homocysteine methyltransferase, NP_001025469.1
MAPTLQDLTPSAGMKKTLQDEIEAILQERIMVLDGGMGTMIQRHKLSEEDFRGQEFKDHARPLKGNNDILSITQPNVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEDISLQTGIKRYVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYKEQAKGLLDGGVDILLIETIFDTANAKAALFAVQKLFEEEYVPRPVFISGTIVDKSGRTLSGQTGEAFVISVSHADPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPHVMAMHLKDFAVDGLVNIVGGCCGTTPDHIREIAEAVKNCKPRVPPATVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRRFAKLIMAGNYEEALSVAKMQVEMGAQVLDINMDDGMLDGPSAMTRFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKFGAAVVVMAFDEEGQATETDPKIRVCTRAYHLLLKKLGFNPNDIIFDPNILTIGTGMEEHNLYAVNFINATKVIKETLPGAKVSGGLSNLSFSFRGMEAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKELLQLCEDLIWNRDPEATEKLLHYAQTQGKGGKKVIQTDEWRNGPLEERLEYALVKGIEKYIIEDTEEARLNQEKYPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETKVLTGKIEDEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDEYFEEILEEYEDIRQDHYESLKERRYLTLRQARENGFHIDWLSEPPPVKPTFLGTRVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFDDKTVGEEAKKVYDDAQNMLQALISQKKLQARGVVGFWPAQSIQDDIHLYAEGAVPQASEPIATFYGLRQQAEKDSASSDPYLCLSDFIAPLHSGIPDYLGLFAVACFGVEELSKAYEEECDDYSSIMVKALGDRLAEAFAEELHERARRELWGYCSGEQLAVADLRRLRYEGIRPAPGYPSQPDHTEKLTVWRLADVEQRTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQIEDYASRKNMSVAEVEKWLGPILGYDTD

		#Homo sapiens
>methylmalonyl Coenzyme A mutase, NP_000246.2
MLRAKNQLFLLSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSV
>5-methyltetrahydrofolate-homocysteine methyltransferase, NP_000245.2
MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKVIQTDEWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYYCLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPILGYDTD

		#Mus musculus
>methylmalonyl-Coenzyme A mutase, NM_008650.2
MLRAKNQLFLLSPHYLKQLNIPSASRWKRLLHQQQPLHPEWAVLAKKQLKGKNPEDLIWHTPEGISIKPLYSRADTLDLPEELPGVKPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAQHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYEAALKLIYEVEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDSVEVLAIDNTSVRKKQIEKLKKIKSSRDQALAEQCLSALTQCAASGDGNILALAVDAARARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELTALGRPDILVMCGGVIPPQDYEFLYEVGVSNVFGPGTRIPRAAVQVLDDIEKCLAEKQQSV
>5-methyltetrahydrofolate-homocysteine methyltransferase, NP_001074597.1
MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEEHFQGQEFKDHSRPLKGNNDILSITQPDIIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVDAYQEQAKGLLDGRVDILLIETIFDTANAKAALFAIQNLFEENYAPPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCSLGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPSTMATHLKDFAVDGLVNIVGGCCGSTPDHIREIAEAVKKCKPRVPPASVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSIAKAQVEMGAQVLDINMDDGMLDGPSAMTRFCNSIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEGDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVNVCTRAYHLLVDKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKFGMDMGIVNAGNLPVYDAIHKDLLQLCEDLIWNKDSEATEKLLRYAQTHGTGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNGEKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARLINGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLACNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLRDDYFEEILEEYEDIRQDHYESLKERKYVPLSQARKHGFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYNDAQNMLNILISQKKLQARGVVGFWPAQSVQDDIHLYAEGVVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFIAPLHSGVCDYLGLFAVACFGVEELSKTYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYSRSEQLGVPDLRRLRYEGIRPAPGYPSQPDHTEKLTMWRLASIEQATGIRLTESLAMAPASAVSGLYFSNVKAKYFAVGKISKDQTEDYALRKNMPVAEVEKWLGPILGYDTD

		#Pan troglodytes
>methylmalonyl Coenzyme A mutase, XP_001146810.1
MLRAKNQLFLLSPHYLRQVKESSGSRLIRQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVEASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSV
>5-methyltetrahydrofolate-homocysteine methyltransferase, XP_514294.2
MSPALQDLSQPEGLKKTLRDEIDAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKVIQTDEWRSGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYYCLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPILGYDTD

		#Rattus norvegicus
>Methylmalonyl-CoA mutase, XP_236965.3
MKKPDTLVEKGWTKGVCLIRHQTRARNGGIGLAEPRAELATPPELTGSGAPAASASGSRALGFDLRGRPPTLFVLIFVWEYSCFTMLRAKNQLFLLSPHYLKQLKDASSYRWKRLLHQQQPLHPEWAVLAKKQLKGKNPEDLIWHTPEGISIKPLYSRADTMDLPEELPGVKPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAQHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDVYEAALKLIYEVEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDSVEVLAIDNTSVRKKQIEKLKKIKSSRDQALAERSLNALTQCAASGDGNILALAVDAARARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVNKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKELSALGRPDILVMCGGVIPPQDYEFLYEVGVSNVFGPGTRIPKAAVQVLDDIEKSLAEKQQSV
>5-methyltetrahydrofolate-homocysteine methyltransferase, NP_110491.1
MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEENFQGQEFKDHSRPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGSLGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQKLFEENYASPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPAMMAMHLKDFAVDGLVNVVGGCCGSTPDHIREIAEAVKNCKPRVPPDSVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDGMLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVSVCTRAYHLLVEKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFAFRGMDAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKDLLQLCEDLIWNRDAEATEKLLRYAQTHGKGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNREKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARVLNGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEILEEYEDIRQDHYESLKERKYLPLSQARKHSFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYEDAQNMLSILISRKKLRARGVVGFWPAQSVQDDIHLYAEGAVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFVAPLHSGVRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLGVTDLRKLRYEGIRPAPGYPSQPDHTEKLTMWRLANIEQATGIRLTESLAMAPASAVSGLYFSNVKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPILGYDTD

		#Xenopus tropicalis
>Methylmalonyl-CoA mutase,
MLRARAQHLLRGRLLAPQRHNPTKLPAFLKLSPTQYPSERLLGNQTLHPEWAALAKKQLKGKDPESLRWHTPEGIVIKPLYTKRDTTELPEELPGVKPFTRGPYPTMYTHRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDMKMLFDGIPLEKMSVSMTMNGAVVPILAIILGYFAPFNILFVPASQNMPKFNSISISGYHMQEAGADAVLELAYTVADGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWADLIEKNFQPKDKKSLLLRAHCQTSGWSLTEQDPYNNVVRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTEDVYQAALKLINEVEEMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYKLEKEESVEVLAIDNTSVRNRQIEKLEKVKASRDNAAAQQCLSAITECAATGKGNILGLAVEAAQARCTVGEITDAMKKVFGEHKASDRMVSGAYRQEFGESEEISFSISRVQKFMDREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELSALGRPDILVICGGVIPPQDYEFLYNAGVSSVFGPGTRIPKAAVQVIDDIERSLDKRQLSL
>5-methyltetrahydrofolate-homocysteine methyltransferase,
MPPTIQHAEPSGVRKRNLQEELDSVLRERIMVLDGGMGTMIQQHTLQEESFRGQEFIDHAKPLKGNNDLLSITQSEIIYKIHKEYLTCGADIVETNTFSSTSIAQADYGLEHLAYRLNKVSAEVARRAADDVTAETGMKRYVAGAMGPTNKTLSVSPSVERPDYRNVTFDELVDAYAEQARGLLDGGVDILLVETIFDTANAKAALFAIQKLFEEDYEPRPIFISGTIVDKSGRTLSGQTGEAFVVSVSHAEPLCIGLNCALGAIEMRPFIEAIGKCTTSYVICYPNAGLPNTFGGYDETPEVTAKHIKDFALDGLVNIVGGCCGTTPAHIREIAEAVKNCKPRIPPTSVFDGYMLLSGLEPFRIGPYTNFVNIGERCNVAGSRRFAKLIMSDNYEEALSVAKAQVEMGAQILDINVDDGMLDGPTAMARFCNYIASEPDIAKVPLCIDSSNFNVIEAGLKCCQGKCIVNSISLKEGEEDFLAKAKKIKQFGAAVVIMAFDEVGQATDTETKVSVCTRAYNLLVEKLNFNPNDIIFDPNILTIGTGMEEHDKYAINFIEATKSIKESLKGARVSGGLSNLSFSFRGMEAIREAMHGVFLYHAIKAGMDMGIVNAGNLPVYDDIDKELLTLCEDLIWNRDPDGTEKLLKYAQTKAKGGKKVIQTDEWRNGSVEERLEYALIKGIEKFVIEDTEEARANKEKYSRPLHIIEGPLMNGMKVVGELFGAGKMFLPQVIKSARVMKKSVGHLIPFMEKEREAMRAISGTLEEDNPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILRAAIENKADIIGLSGLITPSLDEMIFVAKEMERLGIRTPLLIGGATTSRTHTAVKIAPRYNAPVIHCLDASKSVVVCSQLLDENVRDDFLEEITEEYEDIRQDHYESLRERRYLTLEQARNKGLHIDWLSHPKPVRPKLIGTEVYSNYDLEKLRHYIDWKPFFDVWQLRGKYPNRAFPKIFNDKTVGEEAKRLYEDAQNMLNMVISEKKFEARGVVGIWPAHSVQDDILLYADEGNMSSTEAIATFYGLRQQAEKDSASTDPYYCLSDFIAPQHSGVKDYLGVFAVACFGVEELSKVYEKQGDDYSSIMAKALGDRLVEAFAEELHERVRKDLWGYCSEEQLNVSDLRRIRYEGIRPAPGYPSQPDHIEKVTMWKLADVERTTGIKLTESLAMSPASSVSGLMFSSPMSKYFAVGKISKDQVEDYACRKNMPVCEVEKWLGPILSYDPED

		#Danio rerio 
>Methylmalonyl-CoA mutase, AAI39861.1
MLTAQKACISLTARRLLGASISSTLDPQQRTRQFSTAVPLRDEVKIHEAWAALAKKQLKGKNPEDLIWKTPEGISIKPVYTQTDTAKAPDELPGVFPFTRGPYPTMYTYRPWTIRQYAGFSTVEESNKFYRDNIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDTVEDTKLLFDGIPLEKMSVSMTMNGAVIPILAMFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMHAIADIFAYTSKNMPKFNSISISGYHIQEAGADAILELAYTIANGLEYCRTGLKAGLTIDEFAPRLSFFWGIGMNFYMEIAKLRAARRLWATLIKEKFQPKNSKSLLLRTHCQTSGWSLTEQDPYNNVIRTVIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMEALTNDVYNSALKFITEIEDMGGMARAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYRLEKEESVDVLAIDNTAVRNKQIEKLQKVRESRDAEAAKRCLAAIEQCARTRDGNLLELAVEAARARCSVGEITDAMKSVFGEHKASTRMVSGAYRSEFGEHEEIALAHNRVVQFKKHEGRNPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDVGPLFQTPLEVAQQAVDADVHCVGVSTLAAGHKTLVPELIKELRNLNRPDIMVICGGVIPPQDYEFLYASGVSCIFGPGTRIPKAAVEVLDSIEKSLEKNRQAM
>B12-dependent methionine synthase, AAM33342.1
MPPTIHQSPAGRASSLRLELTELLQQRILVLDGGMGTMIQQRHLEEEEFRGQEFKDHPKSLKGNNDILSITQPDVIYSIHKEYLEAGADIIETNTFSSTSIAQADYGMEDLAYRLNKASAEVARRAADDVSAQTGCKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYAEQVKGLLDGGADVLLVETIFDTANAKAALFAIDRLFEESYEARPVLISGTIVDKSGRTLSGQTGEAFVISVSHAQPLCIGLNCALGASEMRPFIEAIGKSTSAFVICYPNAGLPNTFGGYDETPDVTAAHLKEFAVDGLVNIVGGCCGTTPDHIRAIAESVRHVKPRVPPTDVYSDYMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSIAKAQVEMGAQVLDINMDEGMLDGAAAMSRFCNLIASEPDICKVPLCIDSSNFSVIEAGLKCCQGKCIVNSISLKEGEQDFLRRARQVRRYGAAVVVMAFDEDGQATETDQKVQICSRAYHLLIDQAGFNPNDIIFDPNILTIGTGMEEHSMYAINFIRATRIIKESLPGARVSGGLSNLSFSFRGMEAIREAMHGAFLYHAIKDGMDMGIVNAGNLPVYDDIDKELLLLCENIIWNRDPDATEKLLLYAQNNAKGGKKVVQTDEWRTGSVEERLEYALVKGIEKYVVEDTEEARAQTERYPRPLHVIEGPLMNGMKTVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEMMATSGCVEEVDPYQGTVLLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMIPCDRILREAIHNKADIIGLSGLITPSLDEMIHVAKEMERLGLKIPLLIGGATTSKTHTAVKIAPRYSSPVVHVLDASRSVVVCSQLLDEGVRDDYFEEVQEEYEDIRQDHYDSLKDRRFLSLSRAREKGLHIDWFAQPKPVRPQFLGTHVFDTYDLRKLVDFIDWKPFFDVWQLRGKYPNRGYPKIFKDKTVGEGARRVHDDALKLLNRLIDSRGLQARGIVGFWAAQSDGDDIHLYTDDVTSPNTTPVATSHGLRQQAEKDSASSEPYLCVSDFVAPRSSGVQDYVGLFAVSVFGAEELSQKFKKQGDDYRSIMVKALADRLAEAFAEELHVRVRRDLWGYSSEEDLPASDLHKLRYEGIRPAAGYPSQPDHSEKLTMWKLADIQEKTGISLTESLAMSPAASVSGLYFSNPKSTYFAVGKITKEQVEDYALRKQMEVCEVERWLGPILGYDTD

		#Strongylocentrotus purpuratus 
>Urease, XP_001180473.1
MRLSPREQESLLVHEAGALAQKRLARGLKLNHPETVALIASQMQEFVRDGKPVSELMNIGRQLLGVRQVLPGVADMIPEVQIEATFPDGTKLVTIHQPVARENGDLSLALYGSFLPVPDLSVFDQPHLVICPAQAKYFAASDEPITLNAGRATKRLKVTSTCDRPIQIGSHYHFIEANKYLTFDRLASLGMRLNIASGTAVRFSPGETRDVNLVAIAGKRVIRGGNGLVDGPVSKASESSLREKIQQHSFGNQAQVRCSRNAETVSNFTCLMPRLNYIHTYGPTVGDKVRLGDTSLVIEVEHDLISVLGGQLKYGDECKFGGGKVLREGMGQAAHLTSKDTLDTVITNALIVDAVAGIIKADVGIKDGMIVGIGKAGNPDVMDGVTAGMAVGVETEAIAGEGKILTAGGLDAHIHFICPQLAKEAIASGLTTMFGGGTGPATGTCATTCTPGPNHIKNMIQSTDAFPLNFGFTGKGNTSNSDKESCRELEEQIEAGAIGMKLHEDWGSTPEAIRTCLRVAERHDVQVMIHTDTLNESCCVEDTIAAFEGRTIHTYHSEGAGGGHAPDIMKVVGVPNVLPSSTNPTRPFTVNTIDEHLDMLMVCHHLDKNLKEDVAFAESRIRAETIAAEDILHDLGAISIVASDSQAMGRVGEVITRTWQTADKMKIFRGRLSEETGDNDNLRVKRYIAKYTVNPAIAHGMGHLIGSVQVGKMADLVLWNPAFFGAKPDLIIKGGYIAWAQMGMPNASIPTPEPVKTRKMFGAYGKSIGENSVIFVSKAAGAEIQQKYGISKKAVPVT
>Methylmalonyl-CoA mutase, XP_781852.1
MRVSGFTQVDAKDWNAWRRFMELECNVQTHRPEFTKEVFAGVPRVTCISCLHREPLNPEWNKLAEKQLKGADPTEKLTWHSPEGISLKPLFTQQDTAKHPDELPGKYPYTRGPYPTMYAQRPWTIRQYAGFSTVEESNRFYRENIKAGQQGLSVAFDLATHRGYDSDNPRVHGDVGMAGVAIDSVDDMKVLFDSIPLDKMSVSMTMNGAVLPIMAMFIAAAEEQGVSQEQLTGTIQNDILKEFMVRNTYIYPPEPSMRIIGDIFAYTSQHMPKFNSISISGYHMQEAGADTILELAFTIADGLEYCRTGLKAGMDIDEFAPRLSFFWGIGMNFYFEIAKLRAARRLWAHLMKEHFNPKKPNSMMLRCHSQTSGWSLTEQDPYNNVIRTTIEAMAAVFGGTQSLHTNSYDEALGLPTVTSARIARNTQIILQEESGIPKIVDPWGGSHMMENLTDEIYEAANNIIAEIEEMGGMAKAVSDGFCKLKIEECAAKKQARIDSGKEVIVGVNKYKLAVEEPMEVLSIDNTEVREKQINKLKDIKQSRSSQEAEAALNAISEASSGEKNLLECAVQAARARCTVEEISMAMEKVFTRHVASDRMVSGAYKSEYGDDEEIQACISRVEDFEKAEGRRPRLLVAKMGQDGHDRGAKVVATSFADLGFDVDIGPLFQTPSEVAQQAIDADVHAVGVSTLAAGHKTLVPELIKALKNMGRGDIGVIVGGVIPPQDYDFLFQEGVKSIFGPGTRIPVAAIKVVDDIQEELGKRAHAM
>B12-dependent methionine synthase, XP_785401.1
MSLHAMSLMLNCLKAFEVKCIFNNAFKNATDGVLVIYINLGAGAKKAVADESWRKESVEDRLEYSLVKGIDKYAVEDTEEARQNTERYKRPLHIIEGPLMKGMSIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEKEETQKATGQEAFNNGTIVLATVKGDVHDIGKNIVGVVLGCNNYRVIDLGVMTPCEKILQTAIQEKADIVGLSGLITPSLDEMIHVAKEMERLGFSLPLLIGGATTSKTHTAVKIAPCYSSPTIHVLDASKSVVVCSSLIDEDRYDDYVEEVKEEYEEVREDHYDSLKDRKYLSLSEVRKRKFEIDWSNFEPVEPSFIGTKVYEDYDLSLLVPYIDWKPFFDVWQLRGRYPNRGYPKIFNDKLVGEEAKKVYDDAQDMLKKVVDQKLLRASGIVGLYPANSVGDDIHVFSDRETTSGGKPDAVFYGLRQQILNQS

		#Caenorhabditis briggsae 
>Methylmalonyl-CoA mutase, CAP24468.1
MYLQLLKPHLLRCSTRPSSSYTRHPIDQKWAAMAKKAMKGREADTLMWNTPEGIPIKPLYLRSDRECDAERNVELPGQFPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKENIKAGQQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAVDSVEDMRQLFDGINLEKMSVSMTMNGAVIPVLAMYVVAAEESGVSRKLLAGTIQNDILKEFMVRNTYIYPPEPSMRIIGDIFAYTSREMPKFNSISISGYHMQEAGADAVLEMAFTIADGIQYCETGINAGLTIDAFAPRLSFFWGISMNFYMEIAKMRAARRLWANLIKERFSPKSDKSMMLRTHSQTSGWSLTEQDPYNNIIRTTIEAMASVFGGTQSLHTNSFDEALGLPTKFSARIARNTQIIIQEESGICKVADPWGGSYMMESLTDEIYEKALAVIKEIDALGGMAKAVASGMTKLKIEEAAAKKQARIDAGKDIIVGVNKYRLAEEQRVEVLKIDNKKVREEQCAKLNKIRETRDAEKAKKALDAITEGARGDGNLMQLAVEAARARCTVGEISDAMEKVFNRHAAVNRLVSGAYKSEFGETSEMSQVLDRVKSFADRDGRQPRIMVAKMGQDGHDRGAKVIATGFADLGFDVDVGPLFQTPQEAAQQAVDADVHVIGASSLAAGHLTLIPQLIGELNKLGRPDILVVAGGVIPPQDYKELYDAGVALVFGPGTRLPACANQILDKLETALPPAPGKVAAR
>B12-dependent methionine synthase, XP_001679930.1
MTRSSLFKELADIAKERIMIIDGAMGTMIQREYMEEHDFRGEILKDHDKPLKGNNDLLSITRPDIIYKIHKLYLEAGADFIETNTFSGTTIAQADYHCEHLVHEINYQSALVARRACDDVGAATGIRRYVCGAIGPTNRTLSISPSVEKPDFRNVTFQELVKAYGDQARSLIQGGVDVLLVETVFDSANAKAALFAIRTLFEDEGVPEIPVFLSGTIVDMSGRTLSGQTGEAFLVSTKQGKPIAVGLNCALGAKDMRQFVQNMSLWSDTLILCYPNAGLPNALGGYDETPEEMAEVLREFAQDGLVNIIGGCCGTTPDHINAMYKAVQGISPRVPPADPHAGKMLLSGLEPSIVGPETNFVNIGERCNVAGSRRFCNLIKNENYDTAIDVARVQVDSGAQILDVNMDDGLLDGPYAMSKFLRLISSEPDVAKIPVCIDSSDFDVIIAGLESTQGKCVVNSISLKEGEEKFKERARIVKRYGAAVVVMAFDEEGQAAETERKFEICERSYRILTEEVGFNPNDIIFDANILTIATGMDEHANYGMYFIEATRMIRENLPGAHVSGGVSNISFSFRGMEAIREAMHSVFLFYAIKAGMDMGIVNAGALPVYEDIDKPLLQLLEDLLFNRDPEATEKLLVAAQEMKKDGKKADTKTDEWRNTSVEERLKFALVKGIDQFVVADTEEARQNTEKYPRPLNVIERPLMDGMAVVGELFGAGKMFLPQVIKSARVMKKAVAHLLPFMDAERQANIEKMGLDEDESPYQGTVVIATVKGDVHDIGKNIVAVVLGCNNFKVVDLGVMTPCENIIKAAIEEKADFIGLSGLITPSLDEMVHVAKEMNRVGLKIPLLIGGATTSKTHTAVKIAPRYPHPVVHCLDASKSVVVCSSLSDMTVRDAFLQDLNEDYEDVRQEHYESLKDRRFVALGKTREKKFNIDWNKFSPVKPSFIGRREFQNFDFKELIPYIDWKPFFDVWQLRGKYPNRSYPKIFDDADVGGEAKRVFDDAQTWLKKLIDEKVLTANAVVSFLPAASEGDDIHVYDPETGNKLDTFYGLRQQSGREHDQSHFCLSDFIRPLKIGVPDDYLGLFACTAGLGAEEYCKVLEENHDDYASIMVKALADRLAEAYAEYLHKEVRVNLWGYSTNEQLTETDLLSIKYEGIRPACGYPSQPDHTEKRTLWKLLEAEKNGIVLTEHLAMLPAASVSGLYFANPQSQYFAVGKIDEDQVTDYAARKNVPKEEVERWLSPIIGYELD

		#Caenorhabditis elegans 
>Methylmalonyl-CoA mutase, NP_497786.2
MYLQLLKPTLLRCSTRPSSSGAYTRSPIDQKWAAMAKKAMKGREADTLTWNTPEGIPIKPLYLRSDRDCDAQRSVELPGQFPFTRGPYPTMYTQRPWTIRQYAGFSTVEESNKFYKENIKAGQQGLSVAFDLATHRGYDSDNPRVFGDVGMAGVAVDSVEDMRQLFDGINLEKMSVSMTMNGAVVPVLAMYVVAAEEAGVSRKLLAGTIQNDILKEFMVRNTYIYPPEPSMRIIGDIFAYTSREMPKFNSISISGYHMQEAGADAVLEMAFTIADGIQYCETGLNAGLTIDAFAPRLSFFWGISMNFYMEIAKMRAARRLWANLIKERFSPKSDKSMMLRTHSQTSGWSLTEQDPYNNIIRTTIEAMASVFGGTQSLHTNSFDEALGLPTKFSARIARNTQIIIQEESGICNVADPWGGSYMMESLTDEIYEKALAVIKEIDELGGMAKAVASGMTKLKIEEAAAKKQARIDAGKDVIVGVNKYRLDHEQQVEVLKIDNAKVREEQCAKLNHIRATRDAEKAQKALDAITEGARGNGNLMELAIEAARARCTVGEISDAMEKVFNRHAAVNRLVSGAYKSEFGETSEMSQVLERVKSFADRDGRQPRIMVAKMGQDGHDRGAKVIATGFADLGFDVDVGPLFQTPLEAAQQAVDADVHVIGASSLAAGHLTLIPQLIGELKKLGRPDILVVAGGVIPPQDYKELYDAGVALVFGPGTRLPACANQILEKLEANLPEAPGKAASR
>B12-dependent methionine synthase, NP_496353.1
MTRSSLFEELAEIAKERIMIIDGAMGTMIQREYMEEEDFRGEILKDHDKPLKGNNDLLSITRPDIIYKIHKLYLEAGADFVETNTFSGTTIAQADYRCEHLVHEINYQSALVARRACDDVGAATGRRRYVCGAIGPTNRTLSISPSVEKPDFRNVTFQELVKAYGDQARSLIQGGVDVLLVETVFDSANAKAALFAIRTLFEDEGVPEMPVFLSGTIVDMSGRTLSGQTGEAFLVSTKQGKPMAVGLNCALGAKDMRQFVDNMSKWSDSFIICYPNAGLPNALGGYDETPEEMADVLREFARDGLVNIIGGCCGTTPDHINAMYKAVQGITPRVPPQDPHAGKMLLSGLEPSIVGPETNFVNIGERCNVAGSRRFCNLIKNENYDTAIDVARVQVDSGAQILDVNMDDGLLDGPYAMSKFLRLISSEPDVAKIPVCIDSSDFDVIIAGLESTQGKCVVNSISLKEGEEKFKERARIIKRYGAAVVVMAFDEQGQAAETDPKFEICERSYRILTEEVGFNPNDIIFDANILTIATGMEEHSNYGMYFIEAARMIRENLPGAHVSGGVSNISFSFRGMEAIREAMHSVFLFYAIKAGMDMGIVNAGALPVYEDIDKPLLQLLEDLLFNRDPEATEKLLVAAQEMKKDGKKADTKTDEWRSLTVEERLKFALVKGVDQFVVADTEEARQNTAKYPRPLNVIERPLMDGMAVVGELFGAGKMFLPQVIKSARVMKKAVAHLLPFMEIERQANIETMGLAEDESPYQGTVVIATVKGDVHDIGKNIVSVVLGCNNFKVVDLGVMTPCENIIKAAIEEKADFIGLSGLITPSLDEMVYVAKEMNRVGLNIPLLIGGATTSKTHTAVKISPRYPHPVVHCLDASKSVVVCSSLSDMSVRDAFLQDLNEDYEDVRQEHYASLKDRRFTDLNKTREKKFKIDWDKFTAVKPSFVGRREYQNFDLNELIPYIDWKPFFDVWQLRGKYPNRSYPKIFDDADVGAEAKKVFDDAQTWLKKLIDEKILVANAVVSFLPAASEGDDMHVYDPETGNKLDTFYGLRQQSGREHDQPHFCLSDFIKPLKNGVPDDYLGLFACTAGLGAEEYCKTLEKNHDDYASIMVKALADRLAEAYAEYLHKEVRTTLWGYSTNEDLTESDLLSIKYQGIRPACGYPSQPDHTEKRTLWKLLEAEKNGIGLTEHLAMLPAASVSGLYFANPQSEYFAVGKIDQDQVIDYAARKNVPKEEVERWLSPILGYDTD

		#Leishmania major strain Friedlin
>Methylmalonyl-CoA mutase, XP_847984.1
MMRRVPVLLSAAYLPEWIAAAKKELKNRDPSTLTIHSINGFDIKPLYLADDVESHPALPGFFPYTRGVHATMYTGRPWTIRQYAGFSTAEESNNFYKTALKNGQQGLSVAFDLATHRGYDSDHPRVTGDVGMAGVAVDSVEDMKLLFNDIPLDKVSVSMTMNGAVIPVLAFFAVAAEESGVSQEKLRGTIQNDILKEFMVRNTYIFPPTPSMRILGDVMAYVSKRQPKFNSISISGYHIQEAGGHGALELAFTIADGLEYIRCAEQRGLTVDDVAPRFSFFFGIGMNFYCEIAKLRAARTLWATYVKKKFNPKNPKSLLLRTHSQTSGWSLTEQDMENNIIRTTIEAMAAVMGGVQSLHTNAFDEAVALPSVQSSRIARNTQIIIQEETCICSVVDPWGGSYMMEALTQEMIKKASAIIDDVEAKGGMTKCIEEGFPKLMIEESAARRQAAIDSGAETIVGVNKYVNPVDKIHETLRIDDQKVRAGQIAALEKLKATRDKAKVQEMLKKVTEACKDENVNILEAAVEAARARATLGEITSAMEEVYGRYVAKNQVVQGVYYNSYLRGGNKEDQNHVAAVKARVDAFAAKEGRRPRIMVAKIGQDGHDRGAKVVATGLADMGYDVDIGPLFQTPEEVARHAVENDVHICGASSLAAGHRTLIPQLIQELKKLGADDIIVTAGGVIPPDDYQSLYDAGVKLIFGPGTPIPKCAEQMIEVLEARQK
>B12-dependent methionine synthase, XP_001680913.1
MSAMRGERSPVFEELEELFQKRILVLDGGMGTMLQRYKLEETDFRGEEFKNATKDLKGNNDLLCLTQPAKVRDVHYKYAIAGADVVETNTFNSQAVSQSDYETQHLVRRINLAAAKICRDAAEQASRETGRRIFVAGVLGPLNRTASISPSVERPDYRNITYDEIVAAYTEQATALLDGGVDVLLIETIFDSLNAKAALFAVNTLFEDKGYTRLPIMVSGTITDLSGRTLSGQTVDAFYSSMRHGNIISIGLNCALGCREMRPYVERLAEISEGYVTCHPNAGLPNAMGEYDELPEDMARDIRDFAANGWVNLVGGCCGTTPDHIRAIATAVKGIPPRPRGHSSETMVISGLEALHFTHHIGFCNIGERCNISGSLKFKRLVKEGKWEECLAVARQQVEEGAMVLDVNMDDGLIDGVTAMTRFLNMIASDPEVARVPVMIDSSKFHVIEAGLKCTQGTPIVNSISLKVGEEEFLRQARLIRRYGAAVVVMAFDENGQAADDANKTRICKRAYDMLVADGFPPENIVFDPNVLTICTGMEEHNNYAIDFMNAATWIKANLPRAKVSGGISNLSFSFRGFEAIRMAMHSAFLKKMIADGSLDMAIVNAGALPVYTDIEPDLLQLVEDAIYNRTPHSSERILEYAERLKAEKASGGGAEEAKVSKVDEWRNASVEERLSHALIKGIVEFIEDDVEEARTCGKYERPLHIIEGPLMGGMGKVGELFGSGKMFLPQVIKSARVMKKAVAVLVPYMEAEKAALMADTNGASTSRAKRVLMATVKGDVHDIGKNIVGVVLGCNSYEVLDLGVMVSCEKILAAAREHDVDVIGLSGLITPSLDEMVHVAKEMKRMGFNIPLMVGGATTSKQHTAVKIQPHYNKTVHVLDASKAVVTVSNMLGSSEEEFWEEVHETYQEIAEDYLANLKDRVYKPLAFCRENALKIDFVEHPPAPRPRKLGTITISDYSVEMIATRIDWNPFFSVWQVRGTYPNRGFPKLFNCPTVGAEAKRLFDDAQEMLKDIIATRSFRAKAVVTLMPVNSVGDDIEVYKDDTRNEKIATFFGLRQQSEKERGEPYLCISDFIAPKGVAPDYLGSLVVGIFGADKMSEQYEKDNDSYRSIMIKALADRFAEAFTEEVHRIIRTDLWGYAEKETAKTADLIQMQYQGIRPAPGYPSQPDHTEMDTMWRIGEVEERTGVKLSESYAMIPAASVSALVFAHAQSKYFAVGKIQKDQVKDYAERKGWNLDRAESQLSSSLAYN

		#Leishmania infantum JPCM5
>Methylmalonyl-CoA mutase, XP_001466294.1
MMRRVSVLLSAAYPQEWIAAAKKELKNRDPSTLTIHSINGFDIKPLYVADDVESHPALPGFFPYTRGVHSTMYTGRPWTIRQYAGFSTAEESNNFYKTALKNGQQGLSVAFDLATHRGYDSDHPRVTGDVGMAGVAVDSVEDMKLLFNDIPLDKVSVSMTMNGAVIPVLAFFAVAAEESGVPQEKLRGTIQNDILKEFMVRNTYIFPPTPSMRILGDVMAYLSKRQPMFNSISISGYHIQEAGGHGALELAFTIADGLEYIRCAEQRGLTVDDVAPRFSFFFGIGMNFYCEIAKLRAARMLWATYVKKKFNPKNPKSLLLRTHSQTSGWSLTEQDMENNIIRTTIEAMAAVMGGVQSLHTNAFDEAVALPSIQSSRIARNTQIIIQEETHICSVVDPWGGSYMMEALTQEMIKKASAIIDDVEAKGGMTKCIEEGFPKLMIEESAARRQAAIDSGAETIVGVNKYVNPVDKIPETLRIDDKKVRAGQIAALEKLKATRDTAKVQEMLKKVTEACRDEKINILEAAIEAARARATLGEITSAMEEVYGRYVARSQVVQGVYYNSYLRGGNKEDQNHVAAVKARIDAFAAKEGRRPRIMVAKIGQDGHDRGAKVVATGLADMGYDVDIGPLFQTPEEVARHAVENDVHICGASSLAAGHRTLIPQLIQELKKLGADDIIVTAGGVIPPDDYQSLYDAGVKLIFGPGTPIPKCAEQMIEVLEARQK
>B12-dependent methionine synthase, XP_001463251.1
MSAMHGERSPVFEELEEIFQKRILVLDGGMGTMLQRYKLEEKDFRGEEFKNATKDLKGNNDLLCLTQPAKVQDVHYKYAIAGADVMETNTFNSQAVSQSDYETQHLVRRINLAAAKICRDAAEQASRETGRRIFVAGVLGPLNRTASISPSVERPDYRNITYDEIVAAYTEQATALLDGGVDVLLIETIFDSLNAKAALFAVNTLFEDKGYTRVPIMVSGTITDLSGRTLSGQTVDAFYSSMRHGNIISIGLNCALGCREMRPYVERLAEISEAYVTCHPNAGLPNAMGEYDELPEDMARDIRDFAVNGWVNLVGGCCGTTPDHIRAIATAVKGIPPRLRGQPSETMVISGLEALYFTHHIGFCNIGERCNISGSLKFKRLVKEGKWEECLAVARQQVEEGAMVLDVNMDDGLIDGVTAMTRFLNMIASDPEVARVPVMIDSSKFHVIEAGLKCTQGTPIVNSISLKVGEEEFLRQARLIRRYGAAVVVMAFDENGQAADYASKTRICKRAYDMLVADGFPPENIVFDPNVLTICTGMEEHNNYAIDFMNAAAWIKANLPRAKVSGGISNLSFSFRGFEAIRMAMHSAFLKKMIADGSLDMAIVNAGALPVYTDIEPDLLQLVEDAIYNRTPHSSERILEYAERLKAEKASGGGAEEAKVSKVDEWRNASVEERLSHALIKGIVEFIEDDVEEARTCGKYERPLHIIEGPLMDGMGKVGELFGSGKMFLPQVIKSARVMKKAVAVLVPYMEAEKAALMADTNGASTSRAKRVLMATVKGDVHDIGKNIVGVVLGCNSYEVIDLGVMVSCEKILAAAKEHDVHVIGLSGLITPSLDEMVHVAKEMKRMGFGIPLMVGGATTSKQHTAVKIQPHYNKTVHVLDASKAVVTVSNMLGSSEEEFWEEVRETYQEIAEDYLANLKDRVYKPLAFCRENALKIDFVANPPAPRPRKLGTITISDYSLEMIATRIDWNPFFSVWQVRGTYPNRGFPKLFNCPTVGAEAKRLFDDAQEMLKDIIATRSFRAKAVVTLMPVNSVGDDIEVYKDDTRNEKIATFFGLRQQSEKERGEPYLCISDFIAPKGVAPDYLGSLAVGIFGADKMSEQYEKDNDSYRSIMIKALADRFAEAFTEEMHRIIRTDLWGYAEKETAETVDLIRMQYQGIRPAPGYPSQPDHTEMDTMWRIGEVEERTGVRLSESYAMMPAASVSALVFAHAQSKYFAVGKIQKDQVKDYAERKGWNLDRAESQLSSSLAYN

		#Leishmania braziliensis MHOM/BR/75/M2904
>Methylmalonyl-CoA mutase,
MMRRGSILLSAAYPPEWIAAAKKELKNRDPATLTVHSPNGFDIKPIYFRDDVKSHPAMPGFFPYTRGVHSTMYTGRPWTIRQYAGFSTAEESNNFYKAALKNGQQGLSVAFDLATHRGYDSDHSRVAGDVGMAGVAVDSVEDMKLLFKDIPLEKVSVSMTMNGAVIPVLAFFAVAAEESGVSQEKLRGTIQNDILKEFMVRNTYIFPPTPSMRILGDIMAYLNKRQPMFNSISISGYHIQEAGGNGALELAFTIADGLEYIRCAQQRGLAVDDVAPRFSFFFGIGMDFYCEIAKLRAARTLWATYVKKMFNPKNSKSLLLRTHSQTSGWSLTEQDMENNIIRTTIEAMAAVMGGVQSLHTNAFDEAVALPSKQSSRTARNTQIIIQEETHICSVADPWGGSYMMEALTQEMVKRASAIIDDVEAKGGMTKCIEEGFPKLMVEESAARRQAAIDSGAETIVGVNKYINLDNKVPETLRIDNKKVRAGQIAALEKIKATRNNAKVQEMLKKVTEACKDEKINILEVAIEAARVRATLGEITSAMEEVYGRYVAKSQVVQGVYSSSYVKGCSKEDQNHIAAIKARIDAFAVKEGRRPRIMVAKIGQDGHDRGAKVVATGLADMGYDVDIGPLFQTPEEVARHAVENDVHICGASSLAAGHRTLIPQLIQELKQLGADDIIVTVGGVIPPEDYQDLYDAGVKLIFGPGTPIPKCAEQMIEVLEARQK
>B12-dependent methionine synthase, XP_001562504.1
MRGERSPAFEELEELFQKRILILDGGMGTMLQRYKLEEADFRGEEFKNATKEVKGNNDLLCLTQPVKVWDVHYKYAVAGADILGTNTFNAQAVSQSDYETQHLVRRINLAAAKICRDAADQASCETGRRIFVAGVLGPLNRTASISPSVERPDYRNITYDEIVAAYTEQATALLEGGVDVLMVETIFDSLNAKAALFALNTLFDDAGYTRVPIMVSGTITDLSGRTLSGQTVEAFYLSMRHGNIISIGLNCALGCREMRPYIQRLAQISEGYVTCYPNAGLPNAMGGYDEPPEDMARDMNDFATNGWVNLVGGCCGTTPDHIHAMAMAVKSIPPRPKGQRSTTLAISGLEPLYFTNHIGFCNIGERCNLSGSLKFKRLVKEGKWEECLEVARKQVEEGAMVLDVNMDDGLIDGVAAMTRFLNLLASDPDVARVPVMIDSSKFHVIEAGLKCTQGTPIVNSISLKVGKEEFLRQARLIRRYGAAVVVMAFDENGQASDYDSKIRICKRAYDMLVADGFPAENIVFDPNVLTICTGMEEHNNYAVDFMNAAAWIKANLPGAKVSGGISNLSFSFRGFEVIRMAMHSAFLKKMIADGSLDMAIVNAGALPVYTDIEPGLLQLVEDAIYNRTPDSSERILEYADRLKAEAAARGGAEEAKVTKVDEWRNAPVEERLLHALIKGIVEFIENDVEEARTCGKYERPLHIIEGPLMDGMGKVGELFGSGKMFLPQVIKSARVMKKAVAVLVPYMEAEKLALIDSPKGKSVSRSKRVLMATVKGDVHDIGKNIVGVVLGCNSYEVIDLGVMVSCEKILAAAKEYDVDVIGLSGLITPSLDEMVHVAKEMKKMGFKIPLMVGGATTSKQHTAVKIQPHYHKTVHVLDASKSVVTVANMLGSNNEEFWEEVHETYQEIAEDYLANQKDRVYKPLAFCRENALKIDFVANPPAPRPRKLGTITISDYPLEKIVSRIDWSPFFSVWQVRGTYPNRGFPKLFNCPTVGVEAKRLFDDAQEMIKDIIATRSFRAKAVVKLMPVNSVGDDIEVYEDDTRVEKIATFFGLRQQAEKERGEPYLCISDFIAPKGVAPDYLGSLVVGIFGADKMSEQYEKDNDGYRSIMIKALADRFAEAFTEEVHRIIRTDLWGFVERETSETADLIQMQYQGIRPAPGYPSQPDHTEMATIWRLGEVEERTGVKLSESYAMMPAASVSALVFAHAQSKYFAVGKIQKDQAKDYAARKGWYLDRVESQLSSSLAYD

		#Phytophthora infestans T30-4
>UreH, 
MGAADTVTALEGASLPGIIATGLLLGLVHVLTGPDHLSALIVLSAGSSWRSCQLGMRWGCGHSTGLIVVTVCFLALNQRLDVDTFGSYCDFMVGFLMMGLGLWSLRYYLLLRRKLQLKHHPAGETTPLHLEAEVQRLKEDALDSDTEVQKILHAHQLDHHGPPTSIELQESTKKTCCFGLIKADIKNPRTQRLTAFAYGTAHGLAGTGGILGVLPAVILNDWVKSSAYLGAFCVSSIIAMGGFAALYGEVTGRMSRFSDSSLVRVGIFSSCVSLCVGIMWVILVSTGTLDEVFG
>Urease
MRLSPREEEHLMLHTAGALAQKRLARGLRLNYSESVALLATQVLELIRDGKTVAELMTLGAQMLGRRQVMEGVASILDEVQVEGTFPDGTKLVTIHNPISNLDGDLSLALYGSFLPVPKLEVFGAAATVTAIAPGALITQDTDIVLNEGRKARVLQITNLSDRPIQVGSHYHLIEANPYLEMDRKLAYGHRLNIAAGTAVRFEPGDQKTVSIVPIAGNKVITGGNNLATGVVDESKVDAIVAKAVAEGFHHRELELSTLPRHVTKPEFGVCKMPRSVYAQTYGPTTGDVVRLGDMELYVAVEKDMTVYGDECKFGGGKVLREGMGQASGRNSAQVVDTIITNALIVDYTGIYKADVGIKDGLIAGIGKGGNPDVMEGVLPDLIVGVNTEVIAGEGLILTAGGFDAHVHFICPQLCTEALSSGLTTLVGGGTGPATGTNATTCTPGPNHIKMMLQATDSTPMNIGLTSKGNTSLPEGLQDTIDAGAVGMKLHEDWGTTPAAIDNCLNVAEKNDVQVTIHTDTLNESSCVEHTIKAFKGRTIHTYHSEGAGGGHAPDIVTVCGELNVLPSSTNPTRPYTRNTIDEHVDMLMVCHHLDKNIAEDVAFAESRIRGETIAAEDLLHDMGAISIISSDSQAMGRIGEVVTRTWQTADKMKKELGLLPEDAASEHKRDNFRVRRYVAKYTINPAIAHGMAHLIGSVEVNKLADLCLWKPCFFGSKPELVIKGGAIAYAQMGDPNASIPTPQPVKMRPMFGALGAAVGMGSIAFVSKSCVDKKIAQSYGLKKRVEAVRNCRGVTKKDMKLNDALPKIQVDPETYKVHADEKLLTCGPATSLPLTQRFFLF
>methylmalonyl CoA mutase
MYIVTAEEQQVDQKLLSGTIQNDILKEFMDIFGYTSEYMPKYNSISISGYHMQEAQADARLELAFTVADGIEYVRAAQAAGLDVDANGKSLLLRTHCQTSGYSLTEQDPYNKIMRTTVEAMAAVMGGTQSLHTNALDEALGLPTEFSARLARNTQLVLLEETSIPRVADPWGGSYLMETLMQELYDAALEMINEVEELGGMAKAIESAMAKLRIEESATKKQARVDSREETIVGVNKYVVENPDTVDVLTIDNTAAAAQACLQKLRDSAALTESTGPGTRPMYLLNLSVSAARARCTVGEISEALDDVWGRHVSKSSVVSGAYRNEYKHNDEAEAVYNAVVKKIEAFAERFGRRPRMLVAKIGQDGHDRGAKVIASGYSDMGFDVDVGPLFSIPVDADVHCISVSSLEAGHNTLVPALVKVLKKENAEHILVICGGTLRAIIKKSEENDAKGL
>B12-dependent methionine synthase, 
MRSNVTAEEVAMLQRPFVRGETDIFAYLTALMKQRTLIFDGGMGTMIQVHKFTEEDFRSERFKDSPCLVKGNNDLLSITQPHIIKEIHKQYMQIGRAQLIGTNTFSGTTIAQADYQMEHLVYELNYESAKLAREAADEVTQLDPLLPRFVAGSIGPTNRTLSISPNVEDPGFRNVTFDELVDAYYTQVEGLVDGGSDVLLVETIFDTLNAKAAVFAINKYQEATGRKLPLFISGTIVDMSGRTLSGQTTEAFYVSLRHSKPFCIGLNCALGANQMKPFLQRLANVAECFVSVYANAGLPNAMGGYDDTPAMMAEYCEEFSKDRLVNMMGGCCGTTPQHIQAIAKMTTKYDPRPLPELKEPFMWLSGLEDMVVTKERFSFLNVGERCNISGSIRFKRLIMKSDYGTAMDVARQQVEDGAMVIDVNVDDGMLDGVAAMERFLKIAVTEPDVSKVPFMIDSSKFHIVEAGLKCVQGKCIVNSISLKVGKELFMEHARIVKNHGAAVVVMAFDEEGQAATEAEKVRICKRSYDILVNEVGFPPEDIIFDPNILTVATGMEEHNNYGVDFINACRIIKEQNPYCGAVAAAGNKQEWRSKPIGERLTYSLVKGISEFIDQDVEEMRKVADKPLDVIEGPLMDGMNVVGELFGSGKMFLPQVIKSARVMKKAVAYLLPFMEEEKNKRRLANAANGIANEEEDEDSQYAGKVLIATVKGDVHDIGKNIVGVVLGCNNYKIIDLGVMVPCENILAAAKEYNVDVIGLSGLITPSLDEMVHVAREMSKAGLNIPLIVGGATTSKMHAAVKIAPHYSTPEHPVMHVLDASRSVVVVGNLLRQDEERDEFVEEVMEEYEEMQEDYYASLDDIKLVGFQDAKTKSYQIDYTASPPFQKINRVGLHVIEDLPLEELVPIIDWNPFFQTWELRGRYPNRGYPKIFDDEAVGAEARKVFDEAQKLLQEIMDKKLLRVRGVSGIFPAYRDGDDVVVCDPKNTDQDISKFCMLRQQAEKETSDPYMSLADFIAPKGVGQDYIGGFAVGVFGVEEMAAKFEADHDDFNKIMSQAIGDRLAEAFAEYIHREMRVKDWGYAADEVLDKEDLLKVKYDGIRPAPGYPSQPDHTEKRALWDLLKADELIDLNLTDSYMMLPGSAVSALCFAHPDSQYFAVGKIGKDQVVEYAKRKGQTLEETERWLAPILGYDRSARPALEGDTQG
>ribonucleotide reductase
MAPTTSNSTSSATGKVVAGTPKAANAKPSIKLETTATPIDTNFEFRTGPDYKPFTLDSAFVASLENQTPPFGFNGLGELVYMRTYSRVKADGTKERWFETIERVINGTFNMQKKWLQQLGRPWDEEEMNQIAQEMYTRIFQMKFTPPGRGLWAMGSPITEDRGLYAALNNCAFVSTADILELETPSKPFCFLMEAAMLGVGVGFDTKGAGKLLVQGCDESKTSVYVIPDSREGWVESVKMLLEAHFLHHPALKLDYSLIRPAGAPIKGFGGIRSGAGSLTALHVAIESILKPLVGKLLTARGIVDIMNQMGVCVVSGNVRRTAEIAFESAFGWTSNNSIFADIGMDYQPIAEQIVRNGEPGFAWLDNMRNFGRMNGIKDDRDRNASGGNPCLEQTLESYEMCCLVETFPYNHENLEDFLETLKHAYMYAKTVTLGQTQWPRTNEVMKRNRRIGCSMSGIAQFISSRGLNEFQRWCEAGYDRIQEVDKQISTRFAIPRSIKTTSIKPSGTVSLLAGATPGMHYPESRFYIRRMHSTFVVSIPVDVGEGVRTLSDVSAWEQFALASFLQRYWADNQVSCTVTFDPKTEGSQLAHLLDYFQYQLKGINLLPKLELGAYKQMPYEEINGPTYHKMNKSIEPLQFSVIQCTETVMDVPDKFCEACVT

		#Thalassiosira pseudonana CCMP1335
>UreH, 
GLFAGSLHAIAGPDHLAALIPRCCGLPWYRAARIGAVWGLGHGVSATLLGMAGYLVKRGVNLFGHGGVMAIGVSLIVIGLLGIKEAREWESPGESACEVTDAATGEEEVTPNSSPIKTAKSAILFNGILHGFSWDGAPSLAPAVAISTWRGSLTFLISYALGTMAAMTLATTVIGEGTRRASDKLDRPDLPRDLSVGSSFLALIVGV
>Urease
LHLTPRETDHLHLHNAGRLAQYRLARGLKLNVPEAKALIAMQMMEMVRNGQGTVSDLMSIGTQLLGRNQVLPGVAALVRDVQVEATFPDGTKLLTVHDPIGREDGDLELALEGSFLPVPDLSKEEEEEGIVPGQVMVSPTLPPIEINAVSSDGCPEGPHLVEIPVTNTGDRPIQVGSHYPFLETNAALVFDRKAALGRRLNVPSGASVRFEPGETKTVTLVNLGGKRNVVCGNGLTAGVADGDRWGEIEKRMEEKGGFGNVSSAKVPEGKPYVLTRSAYSDAYGPTTGDRVRLGDTSLIARIQADHTHYGDECKFGGGKSLREGMGQMTSVSASLALDCVITNAMIIDAKLGIIKADIGIKGNKIHNIGKAGNPDTMNGVTLTPGKEMIVGATTDVIAGEKMIVTAGGVDTHIHFICPQQCDEAIASGVTTMFGGGTGPSAGTSATTCTPGPGHVEMMLRATDDLPLNFGFSGKGNTSDPNTSIIDVLRSGASGFKLHEDWGTTPSAIDACLTFADEHDVQVTIHTDTLNESGYVDDTLRAVKGRTIHAYHTEGAGGGHAPDIMKIVRESNVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIPEDVAFAESRIRPETIAAEDILHDLGALSMISSDSQAMGRVGEVITRTWQTADKMKQQLGPLEEDAANSHPDGLDDNERILRYVAKYTINPAIAHGMSHLIGSIESGKLADLVLWKPSTFGAKPEMIIKGGAIAWAQMGDPNASIPTPQPVYMRPMFGARPRVAGDGGGTSIAFVSNMAATDGIGERLGLGKEVASVVGTRHVSKADMVRNDATPDIRIDPETFEVVADGKRLWCDPLEKVPLAQRFFLF
>methylmalonyl CoA mutase
NVELWETLATKELSKSKQSVDSLRCERITPEGIAIQPVYYDLDDPNPSMPGVKPYERGPYATMYTNRPWTVRQYAGFSTAEESNKFYRANVAAGQQGLSVAFDLPTHRGYDSDHPRVVGDVGMAGVSIDSVEDMKVLFDGIPLDQISVSMTMNGAVLPTMAMYFREGGGGEDKPSVLSSLRGTIQNDILKEFMVRNTYIYPPKPSMDRVVADIIGFCASHMSKFNTVSISGYHMQEAGADAALELGFTIADGLEYIRTAVERAGLKVDDVAPRYSFFFGIGMNYYMEIAKLRAARRLWSTLVEQHFQPKDPRSLLLRTHCQTSGYTLTEQQPLNNVIRTTIEALAAVQGGTQSLHTNSYDEAIGLPTVQTARVARNTQLILQEEAGVCDVADPWGGSYMMESLTDELAEKAMAIIDEVEEAGGMTAYINSGMAKLRIEESATKKQGRIDSGQDIIVGVNKYRLDAKDEQEERQEVLQIDNSAVREKQIGRLNELKARRNNDEVKAALDALEASAKKNGDNENNLMALCIEAARVRCTLGEISLALENAWDRHVPSSTIVQGAYGASFTNSTTNKDNESEYDHVLNEVKKFEEKEGRRPRILVAKMGQDGHDRGAKVIASGFSDLGFDVDIGPLFQTPEEVALQALDSDVHVIGISSQAAGHKTLLPALRAELTKRGADNIVIVAGGVIPPQDYDFLMNESKCCSAVFGPGTRITDAALGTLRLIEQ
>B12-dependent methionine synthase, 
RIAIYDGAMGTMIQNYAKRNRLEEEEYRGDRFANWKCNMKGNNDQLSITQPHIISGIYKEYLEVGGSDLIGTNTFSSTTIAMADYEMEDYVYELNYEGARLAREACDEVTAKDPTRPRFVVGAIGPTNRTGSISPSVEDPSARNVTFDELVEAYFEQIVALMDGGSDILMVETIFDTLNAKAALYAVGEYLEFSGLDIPVFVSGTLVDQSGRTLSGQTGEAFYASIRHAKPMCVGLNCALGANHMVPFVEKLANCVECFLHVYSNAGLPNAMGGYDETPDMMAIQNKVFFENGWLNMVGGCCGSTPPHIKAIREMSEGYKPRKLPDVGRPKMWLSGLEDLVVDDVHNHLGLPFLNVGERCNISGSIRFKKLMMAGDYGTAMDIAKKQVEDGAHVIDINVDDGMLDGLAAMQKFVKIAVTEPEVAKVPFMLDASKFEIVLAGLKWCQGKCIVNSISLKVGEELFKEQATLLKKHGCAVVVMAFDEEGQAATEDEKVRICKRSYDILVNEVHFPPEDIIFDPNVLTIGTGMEEHANYGVDFINATKTIKEICPYVKISGGISNLSFGFRGVMKIRESIHSVFLQHAILESGMDVGIVNAHEMLALSELEDDIKAACENLVFNKTPDATDVMLEARIEASKNGPAAAEVKQTSWRDLDVIKRLEHALINGISQYIDGDVEEARQQVEKPLHIIEGPLMDGMNIIGDLFGAGKMFLPQVIKSARVMKKAVAYLIPFMEKEKRDKLIAEGKDPEDFDENDDSNFAVLMATVKGDVHDIGKNIVAVVLGCNNYKVYDIGVMCSCEKILEKAKEYNVDVIGLSGLITPSLDEMVVVAKEMSKAGFKQPLLIGGATTSKMHTAVKVSPNYFTLEHPVIHVLDASRSVTVVSSLLGENKEEYVTDIMEEYDEVKDYYAGLEDRYFLTFDQAKQQKLTIDFDTFPPAPAPKKMGVTLIDSVTLEDVVPYIDWNPFFQTWELRGRYPNRGYPKIFNDEAVGSEAKKLFDDAQNLMTEIIANKSMNLKGVVGLFPANRTDEGEDVRIYASEEDRDAGKSLDTFCMLRQQAEKESDDPYLSQADFIAPAGYKDHLGMFAVSCFGCDDLVKKYESEHDDYNKIMSQALADRFVEAFAEYLHRVIRTDMWGYAQNESLNEEDLLKIKYVGVRPAPGYPSQPDHTEKTTMWNVIKAEELAGIELSESLSMMPAASVSALVFAHPQSCYFAVGQVGKDQVESYAERKKMDLPVTERWLSPILNYE

		#Arabidopsis thaliana
>UreH, NP_567976.1
MERLLQPSSSSSSISPSKFPSRTSPFLPRLRSSGLSFVSTHRPESRRVSSISCNSSQIPSLYTPIGSNTTNNSFNGSPKSDESKPNPGFLTRIATSASEQRKTLSTGTVILISAVAVLLLNPLLAPPAFASFQTAAKSGWLTSAWTGFLAGCLHTLSGPDHLAALAPLSIGRSKMESAAVGALWGCGHDAGQVIFGLLFLLLKDRLHIEVLQTWGTRIVGLTLVIIGAMGIKEASEIPEPCVALETDISMVSTEKEALPLPKKKKIGFATFATGVVHGLQPDALMIVLPALALPSRLAGSAFLIMFLVGTVIAMGSYTAFIGSCSEALKEKVPRITEKLTWVSSLVAIGLGLGIVISPFFGFSLY
>UreH, NP_565394.1
MDRLLQPPSSHSIAPSKFQSRPSPLLLHRLHSTNLSTFPSSRRLESRRISSISCFFRQNPSPDTSPGLNQSSNFLIASSQTDASKPNPGFIQRIVSSFEQRKTISAGMVILVSAIAALLLNPILVPPAFASFQTATNSGGAAVVGGKLLRTEVLTSAWTGFFAGCLHTLSGPDHLAALAPLSIGRTRMESAAVGALWGCGHDAGQLIFGLLFLLLKDRLHIEVIRTWGTRVVGLTLLVIGAMGIKEASEMPEPCVVTLENGETDEKSLKKKKIGFATFATGIVHGLQPDALMMVLPALALPSRIAGASFLIMFLIGTVIAMGSYTVFIGSCSEALKEKVPRITEKLTWASSLVAIGLGLAIIVSQFFGFSLY
>TgMTP1, NP_182203.1
MESSSPHHSHIVEVNVGKSDEERIIVASKVCGEAPCGFSDSKNASGDAHERSASMRKLCIAVVLCLVFMSVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSLWAAGWEATPRQTYGFFRIEILGALVSIQLIWLLTGILVYEAIIRIVTETSEVNGFLMFLVAAFGLVVNIIMAVLLGHDHGHSHGHGHGHGHDHHNHSHGVTVTTHHHHHDHEHGHSHGHGEDKHHAHGDVTEQLLDKSKTQVAAKEKRKRNINLQGAYLHVLGDSIQSVGVMIGGAIIWYNPEWKIVDLICTLAFSVIVLGTTINMIRNILEVLMESTPREIDATKLEKGLLEMEEVVAVHELHIWAITVGKVLLACHVNIRPEADADMVLNKVIDYIRREYNISHVTIQIER
>Urease, NP_176922.1
MKLLPREIEKLELHQAGFLAQKRLARGIRLNYTEAVALIATQILEFIRDGDKSVAELMDIGRQLLGRRQVLPAVLHLLYTVQVEGTFRDGTKLVTVHEPISLENGNLELALHGSFLPVPSLDKFPEVHEGVIIPGDMKYGDGSIIINHGRKAVVLKVVNTGDRPVQVGSHYHFIEVNPLLVFDRRKALGMRLNIPAGTAVRFEPGERKSVVLVNIGGNKVIRGGNGIVDGLVDDVNWTVLMETMERRGFKHLEDIDASEGIAGEDPRFTTMISREKYANMYGPTTGDKLRLGDTNLYARIEKDYTVYGDECVFGGGKVLREGMGQGIEQAEALSLDTVITNSVIIDYSGIYKADIGIKNGHIVGIGKAGNPDTMHGVQNNMLIGNKTEVIAGEGMIVTAGAIDCHVHFICPQLVYEAVSSGITTMVGGGTGPAYGTRATTCTPSPFDMKLMLQSTDSLPLNFGFTGKGNTAKPLELRHIVEAGAMGLKLHEDWGTTPAAIDNCLAVAEEYDIQVNIHTDTLNESGFVEHTINAFRGRTIHTYHSEGAGGGHAPDIIRVCGVKNVLPSSTNPTRPYTKNTVDEHLDMLMVCHHLDKNIPEDVAFAESRIRAETIAAEDILHDMGAISIISSDSQAMGRIGEVISRTWQTADKMKAQRGAIDPNMADDDNSRIKRYIAKYTINPAIANGFADLIGSVEVKKLADLVIWQPAFFGAKPEMIIKGGNIAWANMGDANASIPTPEPVISRPMFGAFGKAGSENSVAFVSKAALRKGVKELYGLKKRVVAVSNVRQLTKLDMKLNDALPEITVDPETYVVTANGEVLTCAPADSVPLSRNYFLF

		#Oryza sativa
>UreH, NP_001056620.1
MAMERLISSPLLPRRPPRAAFSRPPPSLAAAPPHHRAGGAASGYGSRPPLASLLLSRHHHHHQPPVLAANPAADVAAGEAVPPATATASRRFLQKVASAAAATLLATIALTLIQPAWAPPALASFHSAAKAGGGIFKSELLSSAWTGFLAGCLHTLSGPDHLAALAPLSIGRSRVESAAVGALWGCGHDAGQVIFGLLFLSLKDRLHIEVIRTWGTRVVGLTLLVIGALGIREATEVPTPCVALENGGGGGGAHRGPLDALPATRKKITFATFATGIVHGLQPDALMMVLPALALPSRVAGAAFLGMFLVGTVVAMGSYTVLIGSCTEALKERVPRITEKLTWAASLVAISMGLGILISQSLGFSLY
>UreH, NP_001049011.1
MERLISKSVAARIPLPGGGSPSRRLAVAGLGGGGGVEPWAGRLRAQPRLGPIAARPHDGVSAPPREAAPAAAVGPPWKLLWSLLPKASRAALFLLVALVTGTLQSSIPYPAHASVQSITKTGGLFTSEILSSGWAGFIAGCLHTLSGPDHLVALAPLSIGRSRLESGLVGALWGCGHDAGQVIFGLLFLLLKDRLHIEILRTWGTRVVGLTLLIIGGMGIREATEVQESSLALEGVDCNITSSEPLQTPAAPRKKKVGFATFATGVVHGLQPDALLMVLPSLALPSRFAGAAFLGMFLMGTVFSMGSYTAFVGSCSEALKEKVPRITEKLTWAASLVAICMGIALLVGQFFGFSLY
>TgMTP1, NP_001054539.1
MDSHNSAPPQIAEVRMDISSSTSVAAGNKVCRGAACDFSDSSNSSKDARERMASMRKLIIAVILCIIFMAVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSLWAAGWEATPQQSYGFFRIEILGALVSIQLIWLLAGILVYEAIVRLINESGEVQGSLMFAVSAFGLFVNIIMAVLLGHDHGHGHGHGHGHGHSHDHDHGGSDHDHHHHEDQEHGHVHHHEDGHGNSITVNLHHHPGTGHHHHDAEEPLLKSDAGCDSTQSGAKDAKKARRNINVHSAYLHVLGDSIQSIGVMIGGAIIWYKPEWKIIDLICTLIFSVIVLFTTIKMLRNILEVLMESTPREIDATSLENGLRDMDGVVAVHELHIWAITVGKVLLACHVTITQDADADQMLDKVIGYIKSEYNISHVTIQIERE

		#Chlamydomonas reinhardtii
>UreH,
MPGSPSPANPPPPPLPSNPRPTSPHTYKLALYISIQTSIVILSQALTPLTIGRNRFAASALGALWGFGHSTGQLILGLVFVVLKERFHDFVPFLDKWAGTVVPLTLIAIGLMGIYESFFEAKEGEGHGHGEEEAAASGLKAGFATYATGIVYGLQPDALFVVIPALALPTKLAAVAYCSMFVIGTVSAMGGYTLLIGTTSQALIKEQPWLQKHLSTIASAIAIMVGLLMLAAGMGFDVPFFS
>B12-dependent methionine synthase, 
MRERIIFIDGAMGTQIQKFTLEEEDFRGERYAKHSHELKGNNDLLVITRPDVISKIHTAYLEAGADIIETNTFNGTWISQSDYELQADVALINRTAAQLAKKCVADFLAKNPGSGPRFVAGAIGPTNKTLSVSPSVENPAFRGITYDEVVDAYYKQAEALVEGGVDMFLVETIFDTLNAKAAMYALEKFFSDKGMRLPVFVSGTIVDNSGRTLSGQTNEAFWNSIRHAKPMAVGLNCALGAKDMLKYVANLAACADCYVFCYPNAGLPNAMGGYDQKGDEMAEEIRPFCEGNLVNAIGGCCGTGPEHIAAIKKMASAYKPRKPVTVPPLMRLSGLEPLNYTPDASNMRRTFLNIGERCNVAGSILFKKAIVNNDFDTAVAIALKQVQQGADVLDINMDDGLIEGVGAMTRFVNLLVSDPEISRVPFMIDSSKFHIVEAGLKCSQGKCIVNSISLKEGEAAFRHQAEVVRRHGAAVVVMAFDEQGQAASYEEKIRICSRAYRILVEEVGFDPQDIIFDPNILTIGTGLPEHNNYAVDFIRATREIKRLCPGSKVSGGVSNIAFSFRGNEAVRRAFHSAFLHHACLAGMDMGIVNAAQVKEDEYSKIDKELLEFVEDVLLNRCENATERMLEYAASLDPKSKPTAKEESWRDLPVEKRIEYALIKGIDEFAVVDTEEARSSGRYTKPLQVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAHLIPFIEEEKRLSGNVGENSNAGCFLIATVKGDVHDIGKNIVSVVLGCNNFKVIDMGVMTPWEKILDAAVEHKADIIGLSGLITPSLDEMVTVAKKMEERGMKTPLLIGGATTSKMHTAVKIAPVYSGPVVHVLDASRSVPVCQAFVDKNDKQRQVRDSYIEEVSEQYADLREEFYASLEDRKYLSLADARKRALAVDWKDPVNQPVKPKVLGNKVIRAFPIEDVLDYIDWNPFFQVWQLRGRYPNRGFPRIFNDATVGSEAKKLYEEAQAMLRDFVVNKRVTLNAVMGLYPAAAVGDDIEVYADDSRAKVVARLAGLRQQAEKDGGEPFYCISDFVAPKGSGVPDYVGMFACSAGHGLEKVIEGYKAAGDDYSYIMAEALADRLAEALAEKLHELVRREYWGYAPDEKLSVDDMLKVKYQGIRPAPGYPSQPDHTEKRTMWELLDAEAATDIKLTESLAMWPAASVSGLYFGGKCSSYFAVGKITREQVEDYAARKKMDIKDAERWLSTMLNYEP

		#Ostreococcus tauri
>UreH,
MAFKSAWAGLLAGCLHTLTGPDHLAALTPLTVGPSRAQNALMGALWGFGHNTGQILFGCIFILLRDKLPLNMDLIGQWGQGIVGLTLVIIGAMGFWESVGGHSHSHSHSHSHDGHSHSHGDASVPMKRDTNFISWTYITGTIHGLQPDSLFLLLPAMTLPRVEAISFLATFFIGTIFAMGTYTYCIGAGTAALEKNNPKFVSYIARGSSAVALGFGVLFIISAVFGLELV
>Urease, 
MTTGFYMRLTPCEVDKLGALVAAGRLAQRRLARGIRLNHPEAVALIAMQCVEFARDPNFVIRGDARALTAAEVQDLGKRVLGRRHVLEGVPELVGDVQIETTFDDGTKLVTIHDAVCADEVDLELALLGSFLPKPNAEAFPPAAKEKTPAPGEICTSKDSLELLAGRLKRKLKITNTCDRPIQVGSHYHLIETNRFLKFDRRRAYGARLAIPSGTAVRFEPGESKTVSVVDIAGKRVVKGGNNLVNGPATADRLEEVMKRVIDGGFGHAEADDLGEGEALMIPRQKYAHMYGPTVGDRVRLGDTNLYITPERDLTMKGEESKFGGGKTLREGMSQQAGVGDADSLDTIITNALIVDHSGIYKADIGIKDGHIVGIGHGGNPDIADVTPGMVVGVNTEAIAAEGCIVTAGALDTHIHYICPQLCVEAVASGITTLLGGGTGPASGTCATTCTPSAAHMRFMLETTDTLPLNFAFTGKGNTASPEGLHEIIKAGAVGMKLHEDWGTTPAAIDNCLTIAEEYDVAVTIHTDTLNESCCVEKSIEAFKGRTIHTYHSEGAGGGHAPDIIKVCGEKMVLPSSTNPTRPYTKNTVDEHLDMLMVCHHLDPEIPEDVAFAESRIRAETIAAEDVLHDMGALSIMASDSQAMGRVGEVIRRTWQTAHSNKEQRGFLEEDANSGADNFRVKRYVAKYTINPAIAHGMSHKVGSLEVGKFADIVIWKPAFFGAKPEIVVKGGQIAWAQMGDPNASIPTPEPVIMRGMFGSLKPGKTCIAFVSAAAAAADVGTEYGLYKRVEAVVKCRGLSKDDMILNNACPKIEVDPETYEVQADGVVLKSQPAQELPLARRYFIV
>B12-dependent methionine synthase, 
MKKSPAFDVIEGIMAKRVMVIDGAMGTAVQRYKLTEDDFRGERYKEHTHDLKGNNDILVLTRPDVIGEIHEAYLAAGADIIETNTFSSTMIAQADYELDKKNEVRDMNIAAARLAKAACEKFTKQNPDKPRFAAGAIGPTNRTLSVSPSVENPAFRACTFDEIVDGYYDQIEALVEGGVDMLLVETIFDTLNAKAAIFAIEKFFDAYGTRLPLFVSGTIVDNSGRTLSGQTNEAFWNSVMHAKPMAIGLNCALGAKDMVPYIENLSKCADCWVFAYPNAGLPNAMGGYDQKGAEMAEDCRVFLEKGLLNGIGGCCGTTDEHIGALADMVAPYTPRKKHGIPDIMRLSGLEPFNYSPDEKDYRKTFINLGERCNVAGSTIFKKAIVDGDFEKALAIALKQVENGAHVIDINMDDGLIDGESAMTRFVNLLVSEPDASKVPFMIDSSKFHVVEAGLKCSQGKCIMNSISLKGGEEEFLKHARIVKRHGAAVVVMAFDEAGQAATEAEKIRICCRAYKLLVEEVGFNPQDIIFDPNILTIGTGMEEHNNYAVDFINATREIKRLCPGCKISGGVSNLAFSFRGNEPVRRAFHSAFLYHACKAGMDMGIVNAAQIDKELLEYVEDVLLNRCTNATERMLEFAATLDPKSKPTELRKKGEWRNQPAEKRLEYALIKGIDEFCIADTEECRIGGKYSSCLEVIEGPLMDGMNIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMDAEKAATGSTEASTAGTFLIATVKGDVHDIGKNIVAVVLGCNNFKVVDIGVMCPCEKILDAVVEHKADILGLSGLITPSLDEMVTVAKEMEKRGMKLPLLIGGATTSKMHTAVKLTPNYSGGVIHVLDASRAVPVAQTLLDDRKNVDFLDDINETYAEMREEFYAGLEDRKYLTLEKARATVQPVDFTVAPNIPVTPKFCGAKSVEVSIDDVLPYIDWNPFFQVWQLRGRYPNRGYPKIFNDETVGSEAKKLFNEANAMIQKIKENKRLTLKGIYGFYPANSVGDDIVVYTDETRSTPQHTFFTLRQQAEKDTDEPYMALSDFIAPKSSGVKDYLGMFVCSAGFGLDELTAEYKAANDDYSYIMAEALADRLAEAFAELLHEQVRKDHWGYAKDEAFSCDDLLKVKYQGIRPAPGYPSQPDHTEKATMWDLMKVKEEIGVELTETFAMLPSASVSGLYFAGACSQYFNVGKITADQVTEYADRKKMDLSEAQRWLGPNLSYEP

		#Ostreococcus lucimarinus
>UreH,
MSVITAFKSAWAGLLAGCLHTLTGPDHLAALTPLTVGPSRAQNALMGALWGLGHNTGQILFGCIFIALRDKLPLNLEVIGQFGQGIVGLTLIIIGAIGFWESMGGHSHSHSHSHSHSHSHSHGSDVPAKRDSSFISWTYITGTIHGLQPDSLFLLLPALALPRVEAISFLATFFIGTIIAMGTYTYCIGAGTAALEKNNPKFVSYIARGSSAVALAFGVLFVISAVFGLDLIF
>Urease, 
MRLTPCEIDKLNILFAAGRVAQRRLARGMRLNHPEAVALIAMQCVELVRDPKFDKDGERRALTSVEVQDLGKRVLGRRHVLDGVPELVGDVQIETTFDDGTKLITIHDAICADDVDLELALLGSFLPKPSEKAFPPATKEKTPAPGEVRTSKDSLELLAGRPKRKLKVTNTCDRPIQVGSHFHLIEANRFLTFDRRRAYGARLAIPSGTAVRFEPGESKTVNMVNIAGNRVVKGGNNLVNGPATADRLDEVMKRVIDGGFGHVDADDLGEGEPLMIPRHKYAHMYGPTIGDRVRLGDTNLYITPERDLTMKGEESKFGGGKTLREGMSQQAGVGDADSLDTIITNALIVDHSGIYKADIGIKDGHIVGIGHGGNPDVADVTPGMVVGVNTEAIAAEGCIVTAGALDTHIHYICPQLCTEAVASGITTLLGGGTGPASGTCATTCTPSAAHMQFMLETTDALPLNFAFTGKGNTASPEGLHEIIKAGAVGMKLHEDWGTTPAAIDNCLTIAEEYDVAVTIHTDTLNESCCVEKSIEAFKGRTIHTYHSEGAGGGHAPDIIKVCGEKMVLPSSTNPTRPYTKNTVDEHLDMLMVCHHLDPEIPEDVAFAESRIRAETIAAEDVLHDMGALSIMASDSQAMGRVGEVIRRTWQTAHSNKEQRGFLEEDANSGADNVRVKRYVAKYTINPAIAHGMSHKVGSLEVGKFADVVIWKPAFFGAKPEIVVKGGQIAWAQMGDPNASIPTPEPVIMRGMFGALKPGKTCIAFVSAAAAAADVGAEYGLNKRVEAVVKCRGLSKDDMVLNNACPRIEVDPETYEVRADGVVLKSQPAQELPLARRYFIV
>B12-dependent methionine synthase, 
MQKRVMVIDGAMGTAVQKYKLSEDDFRGDRYKNHTHDLKGNNDILVLTKPEVISEIHEAYLAAGADIIETNTFSSTMIAQADYELDKKEEVRDMNLAAARLAKAACVKFTEQNPAKPRFAAGAIGPTNRTLSVSPSVENPAFRACTFDEIVDAYYEQIEALVEGGVDLILVETIFDTLNAKAAIFAIEKFFEAYGTRLPLFISGTIVDNSGRTLSGQTNEAFWNSVSHAKPMAVGLNCALGAKDMVPYIENLSKCADCWVFAYPNAGLPNAMGGYDQKGAEMAEDCRVFLEKGLLNGIGGCCGTTDDHIGALAQMVAPYTPRKKHDVPEIMRISGLEPFNYVPNENDYRKTFINLGERCNVAGSSIFKKAIVDGNFEKALAIALKQVEHGAHVIDINMDDGLIDGETAMSRFVNLLVSEPDASKVPFMIDSSKFHVVEAGLKCSQGKCIMNSISLKGGEEEFLHHAKIVKRHGAAVVVMAFDEEGQAATEAEKVRICCRAYKLLVEQLGFNPQDIIFDPNILTIGTGMEEHNNYGVDFINATREIKRLCPGCKISGGVSNLAFSFRGNEPVRRAFHSAFLYHACKAGMDMGIVNAAQVEEDVYEKMDKELLEYVEDVLLNRCTNATERMLEFAATLDPKSTPCNLRKKGAAGGGAVKAAGSGKEWRNQPCEKRLEYALIKGIDEFCIADTEECRVGDKYKSCLEVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMDAEKALTGSTEASTAGTFLIATVKGDVHDIGKNIVAVVLGCNNFKVIDIGVMCPCEKILDAVRESKADILGLSGLITPSLDEMVTVAKEMEKAGMRIPLLIGGATTSKMHTAVKLTPNYSGGVIHVLDASRAVPVAQTLLDKRKHADFMDDINETYAEMRDEFYAGLEDRKYLTLQKARATVKPVDFTAAPNVPVTPKFCGAKAMEVSIDDVLPYIDWNPFFQVWQLRGRYPNRGYPKIFNDETVGPEAKKLFDEANAMITKIKQNKRLTLKGIYGFYPANSVGDDIVVYTDESRTTTHHTFYTLRQQAEKDTDEPYMALSDFIAPKDSGVKDYLGMFVCSAGFGLDELTAEFKAANDDYSYIMAEALADRLAEAFAELLHERVRKDDWGYAKDESFNCEDLLKVKYQGIRPAPGYPSQPDHTEKATMWDLMKVKEEIGVELTETFAMLPSASVSGLYFAGACSEYFNVGKLTSDQVEEYAGRKKMELSEVQRWLGPNLSYEP