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1.  Contact tracing in the control of STD in Ibadan, Nigeria. 
Contact tracing carried out at this clinic was analysed as part of measures for control of sexually transmitted disease (STD). Results showed that 50% of 156 contacts could not be traced at all for various reasons, and that 47% of the contacts were brought in through persuasion by index patients who had been counselled at the clinic. Only four contacts were traced, and two of these attended the clinic. Index patient cooperation is thus identified as the most important factor in the success of contact tracing, because of the high level of illiteracy and poor communications facilities in Nigeria, compared with industrialised countries.
PMCID: PMC1046448  PMID: 6704694
2.  Intraoral condylomata acuminata. A case report. 
Condylomata acuminata occurred intraorally in a 6 year old Nigerian girl. Since she had no skin or genital lesions and no history of sexual contact, the virus was probably acquired from environmental sources. Non-sexual modes of transmission should, therefore, be considered, particularly when the lesions are extragenital.
PMCID: PMC1046219  PMID: 6311323
3.  Chlamydial genital infection in Ibadan, Nigeria. A seroepidemiological survey. 
Sera from patients attending a sexually transmitted diseases (STD) clinic, a family planning clinic, and an antenatal clinic in Ibadan, Nigeria, as well as from male blood donors from the same area were tested for the presence of type specific antichlamydial antibodies using a modified micro-immunofluorescence test. Among men and women attending the STD clinic the exposure rates to Chlamydia trachomatis serotypes D to K (genital pathogens) were 18.7% and 26.7% respectively. Antibody titres suggesting active disease in these men and women were found in 11.8% and 22.7% respectively. The highest rate of exposure (35%) was among women attending the family planning clinic; of these women 25% had antibody suggesting active disease. Titres of IgG antibody in this study were similar to those found among men and women with chlamydial genital infections in the United Kingdom. Antibodies to serotypes D to K were also detected in 10.3% of women attending an antenatal clinic and in 9.9% of male blood donors. The prevalence of antibodies to C trachomatis serotypes A to C and lymphogranuloma venereum serotypes was low. These results suggest that the prevalence of chlamydial genital infections in Ibadan, both among STD patients and especially among those individuals not seeking treatment (family planning and antenatal clinic patients), is high. Since serious sequelae can follow chlamydial genital infections it is imperative to carry out further investigations in this area.
PMCID: PMC1046103  PMID: 7171978
4.  Marshall syndrome: a condition resembling congenital syphilis. 
Marshall syndrome (ectodermal dysplasia) was diagnosed in a 14-year-old boy and is thought to be the first case reported from West Africa. Because of the saddle-nose deformity and bilateral cataracts all patients suspected of having congenital syphilis should be investigated for ocular or auditory defects, which would confirm the diagnosis of ectodermal dysplasia.
PMCID: PMC1045883  PMID: 7214117
5.  Sexually transmitted diseases in tropical Africa. A review of the present situation. 
At present very little information is available on the prevalence and pattern of sexually transmitted diseases (STDs) in many countries of tropical Africa. The available evidence does, however, suggest that these diseases are highly prevalent and that a considerable reservoir of infection exists among the female population. Gonorrhoea is probably the most commonly recognised STD in tropical Africa, frequently causing epididymitis and urethral stricture in men and salpingitis and pelvic inflammatory disease in women. The prevalence of a infectious syphilis is still high, particularly the late manifestations of the disease. The prevalence of the other STDs is also high. Thus, the problem is clearly very serious and the need for improving facilities for diagnosis and treatment urgent; some attempt also must be made to initiate control measures.
PMCID: PMC1045881  PMID: 6894260
6.  Epidemiology of gonococcal vulvovaginitis among children in the tropics. 
In a three-year prospective clinical study, 42 children aged between 1 and 12 years were found to have gonococcal vulvovaginitis. Epidemiological investigations showed that contaminated fomites--particularly bedclothing, underclothing, and towels--and precocious sexual intercourse were the important vehicles of transmission of gonococci to the genital tract of these children.
PMCID: PMC1045786  PMID: 7427697
7.  Gonococcal urethral stricture and watering-can perineum. 
A total of sixteen patients with urethral stricture and/or perineal urinary fistulae (water-can perineum) complicating gonorrhoea were seen at the Special Treatment Clinic, University College Hospital, Ibadan, Nigeria. The patients were aged between 25 and 80 years, and the latent period between the time of original attack of gonococcal infection and the development of complications varied from 4 to 50 years. The rate of divorce or marital separation is high among these patients with late sequelae of gonorrhoea. The factors responsible for the present higher incidence of early and late complications of gonorrhoea among patients in Nigeria and other tropical countries compared with their counterparts in Europe and North American include: (a) Lack of medical facilities in most rural areas; (b) Inadequate treatment of veneral diseases, including the urban areas where self-medication is practised on a large scale by the general population; (c) Illiteracy and ignorance of venereal diseases. The cases of watering-can perineum reported here, and the subsequent chronic pyelonephritis and hypertension, reinforce the plea for early and energetic treatment of acute gonorrhoea in Africa as well as large-scale control measures by the health authorities.
PMCID: PMC1045316  PMID: 1009418
9.  Epidemiology of urethritis in Ibadan. 
PMCID: PMC1048285  PMID: 5032771
10.  Lymphographic studies in acute lymphogranuloma venereum infection. 
Lymphography, a radiological method of demonstrating lymphatic channels and nodes, has been used to investigate three cases of acute bubonic lymphogranuloma venereum (LGV). There is general agreement that LGV has a predilection for lymphatic channels and lymph nodes. However, very little is known of the extent of lymph node involvement in the early bubonic stage and whether there is merely a lymphangitis or complete lymphatic obstruction. The present study was undertaken to determine the lymphographic appearance in acute bubonic LGV, the extent of lymphatic node involvement in early LGV, and the usefulness of the procedure in the management of LGV patients. The buboes were not outlined by this procedure. The vessel phase of the lymphogram appeared normal, while the nodal phase showed a gradient of pathological involvement from the inguinal region lessening towards the lumbar nodes. The main drawbacks of lymphography in LGV are the difficulty of visualizing the lymphatics in the negroid skin and the lack of diagnostic criteria for inflammatory diseases of the lymphatic system. The lymphographic findings in LGV as described here may be regarded as typical of LGV but cannot be accepted as specific for LGV with a high degree of confidence. It is suggested that the procedure could be used for monitoring patients with the severe and late sequelae of LGV infection.
PMCID: PMC1045319  PMID: 1009421
11.  Perigenital cutaneous schistosomiasis. 
Perigenital cutaneous schistosomiasis was diagnosed in a patient who had no previous genitourinary or gastrointestinal symptoms suggesting schistosomiasis; his only symptom was a pruritic papular rash in the perineum. Late cutaneous schistosomiasis due to deposition of ova in the dermis is rare but can affect the genital and periumbilical areas. This report highlights the difficulty in diagnosing cutaneous schistosomiasis and the need for biopsy of itchy cutaneous lesions in patients from localities where the infection is endemic.
PMCID: PMC1045707  PMID: 526849
12.  Guinea worm inguinal adenopathy. 
Genital involvement of Dracunculus medinensis is uncommon, and when it does occur, it usually involves the scrotum. A case has been described in which the inguinal gland was involved producing a bubo simulating that caused by other commoner conditions. It is suggested that the microscopical examination of a wet preparation of bubo aspirates should routinely be practised, especially in tropical countries.
PMCID: PMC1045346  PMID: 139192

Results 1-12 (12)