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1.  ECCB 2014: The 13th European Conference on Computational Biology 
Bioinformatics  2014;30(17):i345-i348.
doi:10.1093/bioinformatics/btu512
PMCID: PMC4147932  PMID: 25161218
2.  Big data and other challenges in the quest for orthologs 
Bioinformatics  2014;30(21):2993-2998.
Given the rapid increase of species with a sequenced genome, the need to identify orthologous genes between them has emerged as a central bioinformatics task. Many different methods exist for orthology detection, which makes it difficult to decide which one to choose for a particular application.
Here, we review the latest developments and issues in the orthology field, and summarize the most recent results reported at the third ‘Quest for Orthologs’ meeting. We focus on community efforts such as the adoption of reference proteomes, standard file formats and benchmarking. Progress in these areas is good, and they are already beneficial to both orthology consumers and providers. However, a major current issue is that the massive increase in complete proteomes poses computational challenges to many of the ortholog database providers, as most orthology inference algorithms scale at least quadratically with the number of proteomes.
The Quest for Orthologs consortium is an open community with a number of working groups that join efforts to enhance various aspects of orthology analysis, such as defining standard formats and datasets, documenting community resources and benchmarking.
Availability and implementation: All such materials are available at http://questfororthologs.org.
Contact: erik.sonnhammer@scilifelab.se or c.dessimoz@ucl.ac.uk
doi:10.1093/bioinformatics/btu492
PMCID: PMC4201156  PMID: 25064571
3.  Editorial 
Bioinformatics  2014;30(12):i1-i2.
doi:10.1093/bioinformatics/btu304
PMCID: PMC4058912  PMID: 24931972
4.  Are graph databases ready for bioinformatics? 
Bioinformatics  2013;29(24):3107-3108.
Contact: Lars.Juhl.Jensen@gmail.com
doi:10.1093/bioinformatics/btt549
PMCID: PMC3842757  PMID: 24135261
5.  Editorial 
Bioinformatics  2013;29(13):i1-i2.
doi:10.1093/bioinformatics/btt282
PMCID: PMC3694647  PMID: 23812973
6.  The rise and fall of supervised machine learning techniques 
Bioinformatics  2011;27(24):3331-3332.
doi:10.1093/bioinformatics/btr585
PMCID: PMC3232371  PMID: 22101152
7.  ISMB/ECCB 2011 PROCEEDINGS PAPERS COMMITTEE 
Bioinformatics  2011;27(13):i2-i6.
doi:10.1093/bioinformatics/btr298
PMCID: PMC3117382
8.  Editorial 
Bioinformatics  2011;27(13):i1.
doi:10.1093/bioinformatics/btr302
PMCID: PMC3293364  PMID: 21685057
9.  Editorial 
Bioinformatics  2010;26(12):i1.
doi:10.1093/bioinformatics/btq238
PMCID: PMC2881413
10.  ISMB/ECCB 2009 Proceedings papers committee 
Bioinformatics  2009;25(12):i2-i5.
doi:10.1093/bioinformatics/btp260
PMCID: PMC2687993
11.  Editorial 
Bioinformatics  2009;25(12):i1.
doi:10.1093/bioinformatics/btp234
PMCID: PMC2687988
12.  ISMB 2008 Organization 
Bioinformatics  2008;24(13):i2-i5.
doi:10.1093/bioinformatics/btn304
PMCID: PMC2718676
13.  Editorial 
Bioinformatics  2008;24(13):i1.
doi:10.1093/bioinformatics/btn204
PMCID: PMC2718667  PMID: 18689809

Results 1-13 (13)