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1.  Pharmacognostical and phytochemical evaluation of Vara Asanadi Kwatha 
Ayu  2012;33(1):130-135.
Vara Asanadi Kwatha (VAK) is a compound Ayurvedic formulation prescribed in the management of obesity. Pharmacognostical study counting both macroscopic and powder microscopy of raw drug exposed the quality and genuineness of all the constituents of VAK. Organoleptic features of coarse powder made out of the crude drugs were within the standard range. Specific gravity of the decoction was 1.0185 and pH was 5.5.Total solid content present in the Kwatha was 4.525% w/v, total ash 0.949% w/v, and acid insoluble ash was 0.052% w/v. Iron assay showed the presence of Fe2O3 as 0.065% w/v. Qualitative scrutiny demonstrated the presence of flavonoids and tannis. Thin Layer Chromatography (TLC) and High Performance Thin Layer Chromatography (HPTLC) were carried out after organizing appropriate solvent system in which maximum three spots were distinguished in TLC and nine spots in HPTLC and most of the Rf values were identical when done with different sample extractive methods. This shows the presence of certain definite constituents in the decoction and is helpful for the easy separation of these constituents.
PMCID: PMC3456851  PMID: 23049198
HPTLC; Pharmacognosy; TLC; Vara Asanadi Kwatha
2.  A comparative study of Kaishora Guggulu and Amrita Guggulu in the management of Utthana Vatarakta 
Ayu  2010;31(4):410-416.
Vatarakta is the major example of Vata vyadhi, caused due to avarana pathology. The scenario of Utthana Vatarakta occurred owing to the margavarana pathology, which can very well be correlated with atherosclerotic peripheral arterial disease. The literature enlists a number of Guggulu prayogas in the management of Vatarakta. An additional cavernous revise was indispensable to bring out the precise outcome of these products. Keeping these visions in mind, the particular comparative study was performed with Kaishora guggulu and Amrita guggulu, which are explained in the same context. This is a single-blind comparative clinical study with a pre-test and post-test design, wherein a minimum of 30 patients of either sex, suffering from Utthana Vatarakta, in an age limit of 16 to 70 years, were selected and randomly categorized into two groups. The 15 patients of group A were treated with oral administration of Tab Kaishora guggulu 1 g thrice a day and the group B patients with Tab Amrita guggulu of the same dose pattern with anupana of lukewarm water. The therapeutic effect of the treatment was assessed in both the groups based on specific subjective and objective parameters. The results obtained were analyzed statistically in both the groups and the comparative effect was assessed using the unpaired “t” -test. In the present study, 80% of the patients from both the groups had madhumeha (Diabetes mellitus), shonita mada (Hypertension) or both. Fifty percent of the patients in group A and nearly 60% of the patients in group B, suffering from Utthana Vatarakta, had the habit of smoking.In both the groups, a statistically significant improvement was observed in all the criteria of assessment. The outcome of the study revealed an identical therapeutic efficacy of Kaishora guggulu and Amrita guggulu in Utthana Vatarakta. The use of Kaishora guggulu or Amrita guggulu as shamana Aushadhas was a perfect selection in the management of rakta margavaranajanya Utthana Vatarakta.
PMCID: PMC3202258  PMID: 22048531
Utthana Vatarakta; Margavarana; Raktavahasrotas; Atherosclerosis; Peripheral Vascular Diseases
3.  Evaluation of the role of Nithyavirechana and Nayopayam kashaya in Tamaka Shwasa 
Ayu  2010;31(3):294-299.
Man has been in steady attempt to find the solutions for the life-threatening and distressing disorders, which afflict the human race. One of such condition is “Tamaka Shwasa,” which is recognized by the name bronchial asthma in contemporary discipline, wherein episodic attacks are the characteristic features, leaving the patient in pathetic situation. Therefore management of this acute respiratory condition is the long mission in the medical society of all types. There is abundance of medicines explained for Tamaka Shwasa in Ayurveda, and it is mentioned that combined Shodhana and Shamana therapy is more effective. Hence the present study is designed to evaluate the role of Nithyavirechana followed by Shamana in the form of Nayopayam kashaya in patients of Tamaka Shwasa. This was a single blind clinical study with pre-test and post-test design where in 20 patients suffering from Tamaka Shwasa of either sex between the age group of 16 and 60 years were subjected to the trial. These patients were treated with Nithyavirechana with Eranda thaila (castor oil) followed by oral administration of Nayopayam kashaya in a dose of 50 ml twice a day. The therapeutic effect of the treatment was assessed based on specific subjective and objective parameters. Results obtained were analyzed for the statistical significance by adapting paired ‘t’ test. Statistical analysis established that Eranda thaila and Nayopayam kashaya are highly effective in counteracting the symptoms of Tamaka Shwasa.
PMCID: PMC3221061  PMID: 22131729
Bronchial asthma; eranda thail; nayopayam kashaya; nithyavirechana; tamaka shwasa

Results 1-3 (3)