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1.  The Broader Autism Phenotype and Its Implications on the Etiology and Treatment of Autism Spectrum Disorders 
Autism Research and Treatment  2011;2011:545901.
The presence of autism-related traits has been well documented in undiagnosed family members of individuals with autism spectrum disorder (ASD). The most common finding is mild impairments in social and communication skills that are similar to those shown by individuals with autism, but exhibited to a lesser degree. Termed the broader autism phenotype (BAP), these traits suggest a genetic liability for autism-related traits in families. Genetic influence in autism is strong, with identical twins showing high concordance for the diagnosis and related traits and approximately 20% of all ASD cases having an identified genetic mechanism. This paper highlights the studies conducted to date regarding the BAP and considers the implications of these findings for the etiology and treatment of ASD.
doi:10.1155/2011/545901
PMCID: PMC3420416  PMID: 22937250

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