Toddalia asiatica var. gracilis (L) Lam is a commonly used medicinal plant in Indian system of Medicine. A detailed pharmacognostic study on the aerial parts of the medicinal plant is presented. Physico-chemical microscopical and fluorescent characteristics have been described. Qualitative phytochemical tests have also been carried out and the results presented.
Water extract of the leaves of Coleus aromaticus Benth. Was tested for its antiurolithiatic activity against calcium oxalate stones in male albino rats. Calcium oxalate stones were induced by feeding 3% w/w sodium oxalate along with normal feed. The water extract of coleus aromaticus (0.5 g/kg and 1.0 g/kg, once, orally for 30 days) was found to be effective in reducing deposition of calcium oxalate. Hence, it is suggested, coleus aromaticus leaves may be effective in the therapy of calcium oxalate stone formation in kidney and urinary tract.
Ethanolic extract of bark of Azadirachta indica showed potent spermicidal activity when tested on rat spermatozoa in vitro. When the extract was applied in 1:1 and 1:2 ratio at tree different concentration using wet drop method, cent percent mortality of spermatozoa was observed within 10 seconds. 10% concentration of the extract was considered as an effective dose.
The indigenous medical practices and the herbal system have an important role in the development of modern medicines. The medicinal plants used in this system are locally available, relatively cheap and also safe and effective. This bioresources can be harnessed for the pharmacological investigation in the modern system of medicine.
Phytochemical screening and physico chemical standards of acetone, chloroform and alcoholic extracts of Ampelocissus latifolia have been performed. These extracts were found to be safe upto a maximum dose of 500 mg/kg. They exhibit significant anti-inflammatory activity that may be due to its inhibitory effect of histamine kinin and prostaglandins release.
The water extract of poochendurappattai was screened for antitumour activity at the doss of 5mg, 10mg, 20mg and 50 mg/kg body weight in rats against methylcholanthrene induced fibrosarcoma. There was 63% regression in the tumour weight at the doses of 10mg and 20 mg/kg body weight. This antitumour activity may be due to compounds like royaleanones since royaleanones are known to possess anticancer activity. Te phytochemical investigation of poochendurappattai revealed the presence of royaleanones.
A variety of rist factors have been suspected for causing the coronary heart disease. 406 cases of both sex groups with age range of 35 to 55 years were selected from three distinct localities of varanasi city. Individuals who reported single or more risk factors of CHD were isolated from the population of the particular areas. After a detailed preliminary screening of the subjects various physical, physiological, psychological and biochemical measurements were carried out. Other basis of initial findings, the cases who sowed abnormal lipid profile with dominant psychological involvement were given the organic extract of Inula racemosa (Pushkarmool), commiphora mukul (Guggulu), centella asiatica (Mandukaparni) and Hypericum perforatum (Basant in prescribed doses continuously for 6 moths. Correction in the lipid profile including triglycerides, blood pressure and the psychological factors like anxiety and depression to a significant level following least drugs treatment indicated the cardioprotective and therapeutic effects of the present formulation.
Hence, by modifying the coronary risk factors, the incidence of CD can be minimized to a great extent as well as the test formulation may also be advocated in the prevention and management of CHD.
Adult Swiss albino male mice exposed to mercuric chloride via drinking water at 5 μg/ml for 100 days revealed significant reduction in the wet weight and severe histopathological changes in male accessory organs, poor level of serum testosterone and infertility. These effects were reduced remarkable and fertility was restored when drug (12.50 mg/mouse/day orally) was administered during mercury exposure for 100days or after Hg-exposure for next 60 days (Post therapy). Natural recovery after mercury exposure for 60 days remind ineffective. Probable action of herbal drug based on the presence of the active principles of constituents (i.e Orchis mascula, Mucuna pruriens, parmelia perlata, Argyreia speciosa, Tribulus terristris, Leptadenia reticulate, Lactuca scariola and Hygrophila spinosa) is discussed in detail.
Arachidic acid; Linoleic acid; Stigmasterol; Dopamin; Glutathione; S; Vit A; B1; C and E; Zn; Ca Cu and Co
T. asthmatica, which belongs to the family Asclepiadaceae is a small twining a plant with long fleshy roots. The plant shows broad activity against EA and DLA cells. The intraperitoneal injection of PE extract obtained from the powdered entire plant material to the tumor cell transplanted animals arrests the tumor growth and prevents the formation of the tumor. A significant increase in the life span of the drug treated tumor bearing mice were found.
The research stud was undertaken to find out socio-economic condition and nutritional status of child labourer in the slum of Rourkela city of Orissa state where form 200 samples were rabdomly chosen and information were collected through structured interview. Form the stud it has been observed that the socio economic conditions and their working conditions were very poor where the range of working hours varied from 6 ours to 17 hours per day ad maximum percentage of samples were used as economic supplementation b imposition of the family. It has also been found that their poor food patter had affected the nutritional status of 59.5 percent of samples.
Shami (Prosopis Cinerarea (L) Druce) of family Mimosaceae is an indigenous plant which has been mentioned in Ayurveda with several clinical properties(1). The plant finds use in one form of the other in various ayurvedic preparations and this has been made in necessary to review the various studies carried out in its chemistry as well as pharmacology.
The ethanolic extracts of aerial shoots of Mollugo cerviana and its leaf derived callus were tested for antimicrobial activity using the filter paper disk assay method. Both the extracts showed antibacterial activity against Bacillus subtilis and Escherichia Coli. The antifungal activity of the extracts against Aspergillus niger and Aspergillus flavus was nil or negligible.
The methanolic extract of the leaf-stalk of curcuma longa LINN, was tested for its minimum Inhibitor concentration (MIC) against Gram positive-staphylococcus aureus, Bacillus pumilus, Bacillus subtilis, klebsiella pnemoniae, bacillus cereus, streptococcus pneumoniae, Lactobacillus arabinosus and gram negative E.coli, shigella dysenteriae, shigella sonnei, shigella boydii, salmonella typhimurium, proteus mirabilis, and Vibrio cholerae strains, further, the ones of inhibition produced by the crude extract against four selected bacterial strains were measured and compared with those produced by the standard antibiotic ciprofloxacin against the same bacterial strains.
The macroscopical characters of the roots, physical constant values, extractive values, colour, consistency and extractive values with different solvents, behaviour on treatment with different chemical reagents, fluorescence characters of liquid extracts and root powder after treatment with different chemical reagents under ultraviolet light of the powdered roots of Tragia involucrata Linn. (Fam Euphorbiaceae) were studied to fix some pharmacognostical parameters which will enable the future investigators for indentification of the plant. Preliminary phytochemical study on different extracts of the roots were also preformed.
Trianthema decandra Linn. (Fam ficoidaceae) Commonly known a “Vellai sharunai’on Tamil and Punaranavi in Sanskrit the roots are used in hepatitis, asthma and suppression of menses the genuine and tree commercial samples of the root of R. Decandra in have been compared pharmacognostically for the first time in the present investigation all the pharmacognostic findings reveal adulteration in the commercial samples.
During the present study a valuable phytotherepeutic information on the various ailments of women was collected from the district, Traditionally the rural women prefer plant medicines than the modern medicines for their diseases including abortion, menstrual trouble, conception disorders, sterility, delivery problems etc, prevailing among them, Eighteen medicinal plants have been reported after making interview of medicine of the villages. The plants are arranged in alphabetical order according to the botanical names followed by family, vernacular names and herbarium number.
The present paper deals with the athnomedicobotany of crude drugs used by a seminomadic ethnic group, the Yanadis, found in Cuddapah district of Andhra Pradesh. This aboriginal group is considered to be the conservators of folklore medicine. Fourteen plant species available in the locality, used by this tribe to cure ailments like epilepsy, hysteria fits and insanity were collected. The valid scientific and vernacular names, plant parts used, therapeutic combinations, mode of administration were enumerated.
Traditional Medicine has its own importance for the treatment of various medical and surgical diseases irrespective of tremendous development of modern medicine. There are number of diseases were after repeated surgery. Fistula-in ano is one such condition which is prone to recurrence even after repeated surgery and can be effectively treated by Ayurvedic medicines. An extensive work has been done on the treatment of Bhagandara by Kshara sutra exploring various aspects of the problem and finding our the solution to them1. the present study is related to similar type of medicated thread known as Aragvadadi Sutra which has been mentioned by sushruta in Bhagandara. It consists of Aragvadha (Cassia fistula), Haridra (Curcuma longa), Agaru (Aquilaria agalocha), Madhu (Honey) and Ghrita (Ghee). This is the first non-caustic thread being tried on different types of Bhagandara. Especially it is a painless thread, non-irritant and very useful in sensitive patients like children, females and elders.
The macroscopic characters of L. lavandulaefolia, physical constant values, behaviour on treatment with different chemical reagents, fluorescence characteristics after treatment with different chemical reagents of the powder of L. Lavandulaefolia were studied to fix some pharmacognostical parameters. Preliminary phytochemical studies and TLC characterization of different extractives has also been performed. These studies will help in future for identifying the plant for further research.
L. Iavandulaefolia; Pharmacognostical studies; Phytochemical study
The microscopic and macroscopic characters of the leaves, physical constant values, behavior on treatment with different chemical reagents, fluorescence characters under ultra violet light after treatment with different chemical reagents of the powdered leaves of Azadirachta indica A. Juss (Family-Meliaceae) were studies to fix some pharmacognostical parameters.
A clinical stud has been performed on the role of Lucomyn, an Ayurvedic uterine tonic in the treatment of an important gynaecological problem i .e-True dysmenorrhoea. The result of said stud is really very encouraging because about 64% patients relieved excellently, 25% patients got average response and only 11% patients got poor effect, With the treatment of said tonic in t dos of I tablespoonful (15 ml) twice daily for 10 weeks.
The macroscopic character of the leaves, physical constant values, extractive values, behavior on treatment with different chemical reagents. Fluorescence characters under ultraviolet light after treatment wit different chemical reagents of the powdered leaves of Cassia tora Linn. (Family: Leguminosae) were studied to characterize some pharmacognostical parameters. Preliminary phytochemical study on different tracts of the leaves were also performed.
Cynodon dactylon commonly known as Durva is considered as a sacred herb by the Hindus and is used in religious rites. It is widely used by the people of India as a traditional medicine for diarrhea, dysentery, catarrhal opthalmia, dropsy, etc. This paper discusses the pharmacognostical and preliminary phytochemical studies of the herb.