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1.  Antitumour Activity of Poochendurappattai in Albino Rats in Albino Rats 
Ancient Science of Life  2000;20(1-2):82-84.
The water extract of poochendurappattai was screened for antitumour activity at the doss of 5mg, 10mg, 20mg and 50 mg/kg body weight in rats against methylcholanthrene induced fibrosarcoma. There was 63% regression in the tumour weight at the doses of 10mg and 20 mg/kg body weight. This antitumour activity may be due to compounds like royaleanones since royaleanones are known to possess anticancer activity. Te phytochemical investigation of poochendurappattai revealed the presence of royaleanones.
PMCID: PMC3336418  PMID: 22557002
2.  ANALYSIS OF TAMIRAPPARPAM 
Ancient Science of Life  1998;17(4):247-250.
Chemical analysis of Tamirapparpam was carried out. The parameters evolved for laboratory made medicine can be used for fixing standards.
PMCID: PMC3331120  PMID: 22556849
3.  ON THE ANTIBACTERIAL ACTIVITY OF SOME SIDDHA MEDICINES 
Ancient Science of Life  1998;17(3):194-202.
Talaka mattirai, Iti vallati meluku, tamibira parpam and Naka centuram of siddha system of medicine were screened for antibacterial activity against S. aureus, S.citreus, S.faecalis B. Subtilis, P.aeruginosa, Coli, S.Boydii, V.cholerae and Klebsiella sp. Talaka matrirai ibihibited the growth of s. faecalis, V.cholerae and B. Subtilis at a concentration of 0.6 mg/ml and 1mg/ml respectively. P.aeruginosa growth was inhibited at a concentration of 0.2mg/ml V. cholerae. at a concentration of 0.6mg/ml and S.boydii at a concentration of 1mg.l by iti vallati meluku. Tambira parpam inhibited the growth of S. faecalis and S. boydii at a concentration of 0.2mg/ml, V.cholerae at a concentration of 0.6mg/ml and S citreus and B. subtilis at a condensation of 1mg/ml there was inhibition of growth of S. citreus and B. subtilis by naka centuram at a concentration of 1mg/ml. Manometric studies revealed the total inhibition of S.boydii by Tambira parpam at a concentration of 1mg/ml while at 0.6mg/ml concentration inhibition was similar to tat of chlroamphenicol (1mg/ml). The antibacterial activity of these medicines was due to ingredients involved in these preparations.
PMCID: PMC3331113  PMID: 22556841
4.  CHEMICAL COMPOSITION OF PATIKARAPARPAM 
Ancient Science of Life  1997;16(4):293-297.
Patikaraparpam, a Siddha formulation in prepared by trituration of potash alum with egg albumin followed by calcinatin. The three authentic laboratories made parpams as well as six commercial samples have been examined for their chemical composition. The analytical data that emerged from the analysis of the above samples showed that seven parpams contained only aluminium sulphate and they did respond to tests for potassium. An inspection of the crude drugs patikaram’ available in the market established that potash alum and ammonia alum are indiscriminateldy taken for use, according to literature, only potash alum should be used in Indian system of medicine. Patikarapparapam is indicated in urinary inflammations and obstructions and is a reputed diuretic. Potassium salts are established diuretic. These studies show that the raw drugs sellers, the pharamaceutists or manufacturers of medicine and the physician as well should make sure that only potash alum is used in Indian medicine.
PMCID: PMC3331171  PMID: 22556804
5.  HEPATOPROTECTIVE ACTIVITY OF NAVAYASA CURNA AND HASAVA COMBINATION 
Ancient Science of Life  1997;16(4):332-336.
Navayasa curna mixed in Lohasava was screened for hepatoprotective activity against carbon tetrachloride induced liver injury in albino rats at a dose of 100mg/kg body weight. The drug reduced liver weight, alkaline phosphatase and GOT activity in liver and chloresterol and GPT activity in serum. There was no effect on protein and liver glycogen.
PMCID: PMC3331172  PMID: 22556808
6.  ANTI-INFLAMMATORY ACTIVIY OF PREMNA TOMENTOSA WILLD. IN ALBINO RATS 
Ancient Science of Life  1993;13(1-2):185-188.
An alcoholic extract of the leaves of Premna tomentosa Willd at a dose of 100 mg/kg body weight exhibited significant anti-inflammatory activity in albino rats. The extract caused reduction in the weight of spleen, thymus and adrenals. It reduced cotton pellet granuloma by 32.21%. The serum biochemical parameters showed reduction in protein, acid phosphatase and transaminases. The activity of P. tomentosa was comparable to phenylbutazone.
PMCID: PMC3336536  PMID: 22556646

Results 1-6 (6)