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2.  ALTERATIONS IN THE SENSITIVITY OF 5TH RECEPTOR SUBTYPES FOLLOWING CHRONIC ASVAGANDHA TREATMENT IN RATS 
Ancient Science of Life  1998;17(3):169-181.
Asvagandha (Withania somnifera) is an important antistress drug has now been sown to have an antidepressant action in clinically depressive patients, However, the mechanism of its antidepressant action has not been studied. Normal rats fed with asvagandha root extract (100mg/kg orally) for 4 and 8 weeks showed enhanced open field behavior and emotional stability along with a moderate but significant enhancement in the functional sensitivity of 5 HT2 receptors in the brain and a reciprocal subsensitivity of the 5HT1A receptors chronic asvagandha treatment (propylactically) was effective in preventing the behavioral deficit in open field activity in an animal model of depression. This was accompanied by an adaptive supersensitivity of the postsynaptic 5HT2 receptors in the brain. The effect of chronic Asvagandha on 5HT receptor subtypes is similar to the action of chronic ECT treatment and several antidepressant drugs.
PMCID: PMC3331105  PMID: 22556838
3.  HYPOGLYCAEMIC PROPERTY OF SHILAJEET AND YASHADA BHASMA 
Ancient Science of Life  1996;16(2):118-121.
Hypoglycaemic activity of shilajeet and Yashada Bhasma was determined in normoglycaemic and alloxanized rats. Significant activity was observed in the treated groups. However, the activity was found to be comparatively milder in shilajatu treated rats compared to Yashada bhasma treated rats.
PMCID: PMC3331154  PMID: 22556779
4.  CONSTITUTIONAL STUDY OF PATIENTS OF DIABETES MELLITUS VIS-À-VIS MADHUMEHA 
Ancient Science of Life  1995;15(1):35-42.
With the changing life style and sedentary habits of the modern era, incidence of diabetes mellitus is increasing throughout the world. The present study was launched to investigate the constitutional and socioeconomic features of diabetic patients and their clinical significance.
PMCID: PMC3331182  PMID: 22556719
5.  ROLE OF NADI PARIKSA IN THE DIAGNOSIS OF UDAR ROGA 
Ancient Science of Life  1994;13(3-4):248-252.
In clinical medicine no physical sign is more revealing than the Nadi Parkisa. The term “Nadi” has been used in several contexts in Ayurvedic classes but gradually this term has been restricted to the Nadi Parkisa i.e. radial pulse examination. Importance of Nadi Pariksa as a diagnostic measure in systemic diseases including cardio-vascular system, G.I.T. diseases (Udar Roga) and Manas Roga is described in Ayurvedic literature. In modern medical science the pulse examination has been given much stress but it is limited to only C.V.S. Nadi is the foremost among the Astasthana Pariksa described in medieval texts on Ayurveda as the main points of general examination of a patient. In Ayurveda Nadi Pariksa is described in Udar Roga and other Vyadhis also. The present paper describes the variations of Nadi in some importants Udar Roga.
PMCID: PMC3336510  PMID: 22556655
6.  CONCEPT OF DEHA PRAKRITI VIS-À-VIS HUMAN CONSTITUTION IN AYURVEDA 
Ancient Science of Life  1994;13(3-4):314-325.
The Ayurvedic literature exhibits a systematic information about psychosomatic constitution and its genetic & environment denominators. According to Ayurveda the psychosomatic constitution, as also known as Deha Prakrti, is represented by a vivid description of the Physique, Physiology & psychological make-up of an individual. The Deha Prakrti is essentially genetically determined and is likely to be influenced by a variety of environmental factors to some extent. Dehaprakrti is the foremost factor which determines the pattern of susceptibility of an individual to different diseases, their prognosis, course and complications.
PMCID: PMC3336518  PMID: 22556666
7.  A CRITICAL STUDY OF THE CONCEPT OF AMLAPITTA AND PARINAMASULA 
Ancient Science of Life  1993;13(1-2):111-118.
The various aspects of theory and treatment of Amlapitta and Parinamasula are presented in this paper.
PMCID: PMC3336531  PMID: 22556636
8.  A CRITICAL STUDY OF THE CONCEPT OF IASCHAEMIC HEART DISEASE IN AYURVEDA 
Ancient Science of Life  1993;13(1-2):102-110.
In this era of Antibiotics decline in infectious diseases is seen but degenerative diseases have established themselves all over world, among which Atherosclerosis and Ischemic Heart Diseases are considered as greatest killer. In view of the increasing morbidity and mortality by these diseases and in absence of safety and adequate efficacy of modern drugs, it has become a timely necessity to understand disease process properly and to explore traditional indigenous system of medicine. So that drugs stated useful in ancient literature for these diseases can be used for I.H.D. Vatika Hrcchula described in Ayurveda simulates with Ischemic Heart Diseases.
PMCID: PMC3336546  PMID: 22556635
9.  THE CONCEPT OF AGING IN AYURVEDA 
Ancient Science of Life  1993;12(3-4):377-387.
The present study reveals that the process of aging was elaborately described in Ayurveda. In order to prology the life span and to promote longevity a separate discipline called Rasayana Tantra was also developed. The sailent feature of this discipline are described in this article.
PMCID: PMC3336553  PMID: 22556616
10.  AYURVEDIC CONCEPT OF HRIDROGA ITS PRESENT RELEVANCE 
Ancient Science of Life  1993;12(3-4):403-413.
Hridroga is among those diseases mentioned in Ayurveda where in the description is quite brief and the Ayurvedic view point needs clarification. In view of the increasing evidence of cardiac disorders in the present times this aspect assumes added importance. Among the five types of Hridroga described, in Vatika variety Ayurveda seems to have conceived the disease entity that comes under Ischemic Heart Disease. None of the other Cardiac afflictions seem to have been described under Hridroga. It seems that a few of the presenting features based on this Acute/important/predominant nature have been described Vatika Sotha and Swasa. It looks as though pain dominating heart disease is conceived as Hridroga. When oedema is found to be the main presenting feature it is kept under Vatika sotha and when Dysponea is the main symptom it is described as Swasa. The present article undertakes to discuss this point in detail, based on Ayurvedic concepts as well as current knowledge on medicine.
PMCID: PMC3336558  PMID: 22556620
11.  PERSPECTIVE IN PLANT DRUG RESEARCH 
Ancient Science of Life  1990;9(3):154-158.
Plant medicine becomes more popular thought the world in these days probably of its latest toxicity. Ayurveda that leads in plant medicine preserves the natural form of herbs maximum, in various pharmaceutical preparations. Isolation of active principles has not proved much fruitful. However, the need of hour is cultivation of more medicinal plants along with popularization of their use traditional simpler forms.
PMCID: PMC3331326  PMID: 22557691
12.  CONCEPT OF PRAMEHA/MADHUMEHA (CONTRADICTIONS AND COMPROMISES) 
Ancient Science of Life  1989;9(2):71-79.
Of all the misleading statements Caraka's categorical declaration that all pramehas if not treated ends up as Madhumeha stands formost. Outlining a common samprapti for all Mutratipravrittaja Rogas appears to be the basic misleading efforts. Extremely limited description at certain points only adds to the confusion. Untiring efforts of the enthusiastic scholars to prove that Madhumeha is synonymous with Diabetes Mellitus have failed to help. The present study undertakes to discuss these aspects in detail and endeavours to come out with some solutions without compromising much on the classical concepts.
PMCID: PMC3331310  PMID: 22557679
13.  THE KALPA METHOD OF THERAPY IN CHRONIC DISEASES 
Ancient Science of Life  1989;9(1):7-10.
In chronic diseases, the Kalpa method of therapy prescribed in Ayurveda for revitalization and overall improvement of health is discussed in this paper. Also reports here that clinical trial of Agrogyavardhini Kalpa in chronic GIT disease confirms the efficacy of Kalps therapy in boosting the general health of the patient as reflected by its nutritional status etc. Clinical symptoms also improve and thus moving that the Arogyavardhini exerts multi dimensional influence on the disease.
PMCID: PMC3331308  PMID: 22557666
14.  EFFECT OF RICE, WHEAT AND ARAHARA DIET ON PEPTIC ULCERATION: A CLINICAL (RETROSPECT) AND EXPERIMENTAL STUDY 
Ancient Science of Life  1989;8(3-4):250-257.
In this experimental study of 65 ulcer patients and 25 healthy persons of this locality revealed an affinity of rice with ulceration. Experimental study conducted on 32 albino rats also confirmed the ulcerogenic property of rice. Arahara (red gram, Cojanus Ccaja) and to some extent wheat were found protective against peptic ulcer probably because of their high mucin output. Therefore, the study finds that the addition of wheat and pulses like Arahara in the diet of high prevalent area may bring decline in the incidence of peptic ulcer.
PMCID: PMC3336730  PMID: 22557658
15.  EFFECT OF CERTAIN YOGIC ASANAS ON THE PELVIC CONGESTION AND IT'S ANATOMY 
Ancient Science of Life  1984;4(2):127-128.
20 patient including 6 females and 14 males, between 20 years to 30 years of age, with complaints of chronic constipation refractory to various treatments by medicines, belching, sense of heaviness in the lower abdomen or pelvic region, offensive discharge from vagina (leucorrhoea) and bleeding per rectum with discomfort in the region of perineum were observed under instructions and supervision to practice certain yogic exercises for a period of three years. Viparitakarani, Goraksa asana, Uddyana Bandha and Mula Bandha (Nauli, Perineal Shrug) when practiced, relieved these patients were asked not to take any purgatives or laxatives. It was concluded from the present study that these complaints which can be ascribed to poor hemodynamics in the region of pelvis and perineum disappeared and patients showed obvious improvement after practicing these Asanas which reduced pelvic congestion and increased blood flow to the pelvic viscera i.e rectum, anal canal, prostate, uterus, vagina and levator ani and perineal muscles
PMCID: PMC3331493  PMID: 22557465
16.  CLINICAL EVALUATION OF MEDHYA RASAYANA COMPOUND IN CASES OF NON-DEPRESSIVE ANXIETY NEUROSIS 
Ancient Science of Life  1982;2(1):11-16.
The data emerging out of the clinical trial indicated significant clinical relief and favourable shift of grades of the clinical components of anxiety namely nervousness, palpitation, insomnia, irritability, lack of concentration etc. Following Medhya Rasayana therapy. The elements of underlying depression as measured by a depression scale were also found reduced. The patients reported an increasing feeling of well being and showed a tendency of gain in body weight besides corrections of pulse rate and blood pressure.
PMCID: PMC3336698  PMID: 22556946

Results 1-16 (16)