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1.  Phytochemical and Pharmacological Evaluation of Ampelocissus Latifolia 
Ancient Science of Life  2000;20(1-2):14-18.
Phytochemical screening and physico chemical standards of acetone, chloroform and alcoholic extracts of Ampelocissus latifolia have been performed. These extracts were found to be safe upto a maximum dose of 500 mg/kg. They exhibit significant anti-inflammatory activity that may be due to its inhibitory effect of histamine kinin and prostaglandins release.
PMCID: PMC3336417  PMID: 22556992
3.  THE EFFECT OF AQUEOUS EXTRACT OF ORTHOSIPHON THYMIFLORUS ON ISOLATED SKELETAL MUSCLES 
Ancient Science of Life  1998;18(1):46-49.
Effects of an aqueous extract of orthosiphon thymiflorus on acetyl choline induces contraction on isolated frog rectus abdominis muscle were studies. The aqueous extract of orthosiphon thymiflorus produced significant inhibitory effect on the dose response curve of acetyl choline. It is concluded that the aqueous extract of orthosiphon thymiflorus  may exert an inhibitory effect on the skeletal muscle contraction and may be due to inhibition of the effect of acetylcholine at the receptor site.
PMCID: PMC3331065  PMID: 22556868
4.  ANTI – INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF THE ROOT, BARK AND LEAVES OF AZADIRACHTA INDICA 
Ancient Science of Life  1998;18(1):29-34.
Azadirachta indica is a plant of varied uses in Ayurveda since ancient times and is highly extolled by expert physicians and as well as practitioners of folk medicines. Almost every part of the tree has long been used in folklore and traditional systems of medicine for the treatment of a variety of human ailments. The 50% acetone extract of the root, bark and leaves of A. indica sowed marked anti- inflammatory activity in carrageenan induced edema in rats, Antimicrobial activity was also tested.
PMCID: PMC3331067  PMID: 22556865
5.  ANTI – INFLAMMATORY ACTIVITY OF VOLATILE OIL OF PSIDIUM GUAJAVA 
Ancient Science of Life  1998;17(4):300-304.
Volatile oil of Psidium guajava leaves obtained by steam distillation was given orally to study its effects on the exudation and proliferative phases of the inflammatory reaction, using technique of carragenin induced paw edema and cotton pellets in male albino rats. The anti inflammatory activity as compared with ketorolac tromethamine. In carragenin induced edemas,. 0.8ml/kg of the volatile oil ad anti-inflammatory activity as that of ketorolac tromethamine. The oil was also found to be potent in cotton pellet granuom studies. Preliminary investigation revealed that the volatile oil fraction consist sesqueterpene which may be responsible for its anti inflammatory activity.
PMCID: PMC3331121  PMID: 22556859
6.  ANTI-ULCER ACTIVITY OF THE ALKALI PREPARATION OF THE ROOT AND FRESH LEAF JUICE OF MORINGA OLEIFERA LAM 
Ancient Science of Life  1998;17(3):220-223.
The alkali preparation of the root and fresh leaf juice of Moringa oleifera possessed significant dose –depen-dent anti-ulcer activity in experimentally induced acute gastric ulcers with aspirin, the anti-ulcer effect of the alkali preparation of the root seems to be more pronounced than that of the fresh leaf juice. Te anti-ulcer activity of the alkali preparation of the root could be due to its content of alkaloids or its anticholinergic and antihistaminic activities, or a combination of these factors.
PMCID: PMC3331106  PMID: 22556845
7.  HYPOGLYCAEMIC ACTION OF MOMORDICA CHARANTIA IN NORMAL AND DIABETIC MICE 
Ancient Science of Life  1997;17(1):32-35.
the hypoglycemic effect of the ethanolic extract of Momordica charantia (cucurbitaceae) was investigated in both normal and streptozotocin – induced diabetic mice. The ethanolic extract of Unriped fruits of M. charantia (800mg/kg) reduced the blood glucose of normal mice from 172 ±3 to 136 ± 5 mg/100ml 4 hours after intrapertitoneal administration (P<0.001), and also significantly lowered the blood glucose of streptoxotocin induced diabetic mice from 686± 60 to 407± 35 mg/100ml under similar conditions (p<0.01). The possible mechanism of hypoglycemic action of M.Charantia is due to the increased glucose uptake in liver cells because it markedly lowers the blood glucose levels in streptozotocin induced diabetic mice.
PMCID: PMC3331083  PMID: 22556818
8.  EFFECT OF L-DOPA AND L- METHIONINE SUPPLEMENTATION ON BIOPRODUCTION OF EMENTINE IN CALLUS CULTURES OF CEPHAELIS IPECACUANHA 
Ancient Science of Life  1996;16(1):74-78.
Callus cultures were induced from leaf segments of Cephaelis ipecacuanha on modified gamborg medium containing 2,4 – dichlorophenoxy acetic acid (2mg/1) Indole acetic acid (1mg/1), kinetin (1mg/1) and sucrose (20g/1). The biogenetic profile for alkaloids was established. The established callus cultures were transferred to modified gamborg medium supplemented with L- DOPA (40 mg/1) and L methionine (3mg/1). After four weeks of their growth, the biomass and medium were extracted for emetine alkaloid and analysed by HPLC. The bioproduction of emetine was found to be extracellular in nature. The emetine content had increased to 0.587% mg FW as compared to control cultured (0.0245% mg FW).
PMCID: PMC3331131  PMID: 22556774

Results 1-8 (8)