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1.  EFFECT OF CONTAINER ON AYURVEDIC DRUGS – A SELECT STUDY 
Ancient Science of Life  2004;24(1):11-21.
Effect of packing material on the stability of four Ayurvedic drugs viz., Hingvatsaka Curna, Brahmi ghrta, Dasamula Kvatha Curna and Ajamodarka have been studied by distributing the drugs in different containers by observing the physical and biological changes. The study revealed that Hingvatsaka Curna keeps well for at least 6 month, Ajamodarka is stable for minimum period of six months when stored in glass bottle exposed to light. Dasamula K vatha Curna showed the presence of insects at the completion of three months. In the second month itself Brahmi ghrta becomes rancid on storing in glass and amber colored bottles.
PMCID: PMC3330913  PMID: 22557145
Container effect; Hingvatsaka Curna; Brahmi ghrta; Dasamula Kvatha Curna; Ajamodarka
2.  ANALYTICAL STUDIES ON MATTAN TAILAM 
Ancient Science of Life  1999;18(3-4):199-204.
Mattan tailam, a siddha herbo-mineral oil was prepared and chemically analysed. The physico chemical parameters and thin layer chromatographic pattern were evolved to lay down the standards, The data presented can be used for fixing standards to mattan tailam.
PMCID: PMC3336475  PMID: 22556891
3.  ON THE ANTIBACTERIAL ACTIVITY OF SOME SIDDHA MEDICINES 
Ancient Science of Life  1998;17(3):194-202.
Talaka mattirai, Iti vallati meluku, tamibira parpam and Naka centuram of siddha system of medicine were screened for antibacterial activity against S. aureus, S.citreus, S.faecalis B. Subtilis, P.aeruginosa, Coli, S.Boydii, V.cholerae and Klebsiella sp. Talaka matrirai ibihibited the growth of s. faecalis, V.cholerae and B. Subtilis at a concentration of 0.6 mg/ml and 1mg/ml respectively. P.aeruginosa growth was inhibited at a concentration of 0.2mg/ml V. cholerae. at a concentration of 0.6mg/ml and S.boydii at a concentration of 1mg.l by iti vallati meluku. Tambira parpam inhibited the growth of S. faecalis and S. boydii at a concentration of 0.2mg/ml, V.cholerae at a concentration of 0.6mg/ml and S citreus and B. subtilis at a condensation of 1mg/ml there was inhibition of growth of S. citreus and B. subtilis by naka centuram at a concentration of 1mg/ml. Manometric studies revealed the total inhibition of S.boydii by Tambira parpam at a concentration of 1mg/ml while at 0.6mg/ml concentration inhibition was similar to tat of chlroamphenicol (1mg/ml). The antibacterial activity of these medicines was due to ingredients involved in these preparations.
PMCID: PMC3331113  PMID: 22556841
4.  HEPATOPROTECTIVE ACTIVITY OF NAVAYASA CURNA AND HASAVA COMBINATION 
Ancient Science of Life  1997;16(4):332-336.
Navayasa curna mixed in Lohasava was screened for hepatoprotective activity against carbon tetrachloride induced liver injury in albino rats at a dose of 100mg/kg body weight. The drug reduced liver weight, alkaline phosphatase and GOT activity in liver and chloresterol and GPT activity in serum. There was no effect on protein and liver glycogen.
PMCID: PMC3331172  PMID: 22556808
5.  ANTI-INFLAMMATORY ACTIVIY OF PREMNA TOMENTOSA WILLD. IN ALBINO RATS 
Ancient Science of Life  1993;13(1-2):185-188.
An alcoholic extract of the leaves of Premna tomentosa Willd at a dose of 100 mg/kg body weight exhibited significant anti-inflammatory activity in albino rats. The extract caused reduction in the weight of spleen, thymus and adrenals. It reduced cotton pellet granuloma by 32.21%. The serum biochemical parameters showed reduction in protein, acid phosphatase and transaminases. The activity of P. tomentosa was comparable to phenylbutazone.
PMCID: PMC3336536  PMID: 22556646
6.  STUDIES ON COMMERCIAL SAFFRON 
Ancient Science of Life  1991;10(3):187-190.
Two commercial samples of saffron were analysed for moisture and ash contents, solubility in water, action with sulphuric acid, presence of foreign dyes and colour intensity of water soluble solution.
The moisture content in Laccha was 12.7% while it was 11% in Mogra. The ash was 4.7% in both the samples. The water soluble matter in Laccha was 52.7% and 45.8% in Mogra. There was no foreign dye in these samples. The colour intensity of 0.02% saffron solution of both the samples corresponded to 0.07% of potassium dichromate at 470 mm.
PMCID: PMC3331286  PMID: 22556531
7.  STUDIES ON THE STANDARDISATION OF MAHALAKSADI TAILA 
Ancient Science of Life  1989;9(1):28-30.
Malaksadi taila was prepared as per Ayurvedic formulary and was analysed. The specific gravity, saponification number, iodine number and acid number were 0.915, 199, 102 and 2 respectively. The drug resolved into two spots in the solvent n-butanol, acetic acid, water (75:15:10). The visible spectrum showed two peaks at 420-30 nm and 660 nm.
PMCID: PMC3331303  PMID: 22557672
8.  PREPARATION OF “777 OIL” USED FOR PSORIASIS IN SIDDHA MEDICINE BY MODIFIED METHOD 
Ancient Science of Life  1988;8(1):17-19.
“777 oil” a coded drug of Siddha system of medicine was prepared and analyzed in the paper. The drug showed 3.62, 13.57 and 266.9 Iodine value, acid number and saponification number respectively. The bark which was one of the ingredients in the drug was possessing 0.63% nitrogen in the acid soluble portion. The bark also exhibited proeolytic activity and the optimum pH was 4.
PMCID: PMC3331347  PMID: 22557623
9.  COMPARATIVE AND FERMENTATION STANARDISATIOND STUDIES ON DASAMULARISHTA 
Ancient Science of Life  1988;8(1):68-70.
Asavas and arishtas are produced by fermentation in an earthen pot according to textual procedure. The size and shape of the pot and the quantity of the drug. That can be taken in a pot for fermentation is not mentioned in the literature. The present Study was taken up to determine the quantity of drug that can be fermented in an earthen Pot to obtain best results.
Dasamularishta was fermented in different volumes in earthen pots of identical size, shape and capacity, as well as in stainless steel vessel and porcelain jar.
The drug filled up to 3/4th of the volume of the earthen pot had shown better results than the earthen pots containing various volumes of drug. The stainless steel container and porcelain jar also showed comparable results to the earthen pot fermented drug. Thin layer chromatography of different preparation showed five spots.
PMCID: PMC3331353  PMID: 22557633
10.  PROCESS AND PRODUCT STANDARDISATION OF “77 OIL” USED FOR PSORIASIS IN SIDDHA MEDICINE 
Ancient Science of Life  1986;6(1):35-41.
“777 oil” is a code drug of the Siddha system of medicine used in the treatment of Psoriasis. The drug is derived from the leaves Wrightia tinctoria by insolation, with coconut oil as base. The present study is aimed at comparing the drug prepared by insolation with that prepared in darkness.
Analytical studies carried out in both the drugs showed difference in acid number without exposing to sunlight. The drugs showed changes in acid and iodine numbers on exposure to sunlight.
Studies on Thin Layer Chromatography showed no difference between the two drugs. However semi quantitative chromatography showed that two spots were more in concentration in the drug prepared in darkness than the drug processes in sunlight. Except one spot all the spots Rf values are identical to raw coconut oil.
In analytical studies carried out in shade dried leaves of Wrightia tinctoria showed the presence of iron calcium and ammonium. Alcohol had maximum extractive matter.
PMCID: PMC3331391  PMID: 22557546

Results 1-10 (10)