In the title compound, C20H22O5, the tetra­hydro­pyran, cyclo­hexene and cyclo­hexane rings of the xanthene ring system adopt half-chair, half-boat and chair conformations, respectively. The mean plane of the four roughly planar atoms of the tetra­hydro­pyran ring (r.m.s. deviation = 0.111 Å) forms a dihedral angle of 82.91 (4)° with the meth­oxy­benzene group. In the crystal, mol­ecules are linked via O—H⋯O and C—H⋯O hydrogen bonds into sheets lying parallel to the ac plane. The crystal is further consolidated by weak C—H⋯π inter­actions.

In the title compound, C19H20F6N2O8, the eth­oxy and ethyl groups are disordered over two sets of sites, with occupancy ratios of 0.212 (18):0.788 (18) and 0.746 (6):0.254 (6), respectively. The piperidine ring adopts a chair conformation. In the mol­ecule, intra­molecular O—H⋯O hydrogen bonds form two S(6) ring motifs. In the crystal, mol­ecules are linked via O—H⋯O and C—H⋯O hydrogen bonds, forming dimers.

The asymmetric unit of the title compound, C25H35NO6, contains two independent mol­ecules. In each mol­ecule, the 1,4-dihydro­pyridine ring adopts a flattened boat conformation. The dihedral angles between the 1,4-dihydro­pyridine and benzene rings are 87.55 (7) and 87.23 (7)°. In one of these mol­ecules, one of the isobutyl groups is disordered over two sets of sites, with an occupancy ratio of 0.890 (2):0.110 (2). In the crystal, mol­ecules are linked through N—H⋯O, O—H⋯O and C—H⋯O hydrogen bonds forming two-dimensional networks parallel to the ab plane. The crystal structure is further stabilized by weak C—H⋯π inter­actions.

In the title compound, C17H17Cl2NO2, the central 1,4-dihydro­pyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydro­pyridine ring at positions 3 and 5 have synperiplanar (cis) or anti­periplanar (trans) conformations with respect to the adjacent C=C bonds in the dihydro­pyridine ring. The 2,4-dichloro­phenyl ring is almost planar [r.m.s. deviation = 0.0045 (1) Å] and almost perpendicular [89.27 (3)°] to the mean plane of the dihydro­pyridine ring. In the crystal, an N—H⋯O hydrogen bond links mol­ecules into a zigzag chain along the ac diagonal. C—H⋯Cl contacts form centrosymmetric dimers and additional weak C—H⋯O contacts further consolidate the packing.

In the title compound, C20H22O5, an S(6) ring motif is formed by an intra­molecular C—H⋯O hydrogen bond, which contributes to the stabilization of the mol­ecule. In the xanthene system, the cyclo­hexane ring adopts a chair conformation, the cyclo­hexene ring adopts a half-boat conformation and the tetra­hydro­pyran ring adopts a half-chair conformation. The mean plane of the four essentially planar atoms of the tetra­hydro­pyran ring [r.m.s deviation = 0.092 (1) Å] forms a dihedral angle of 64.13 (6)° with the mean plane of the meth­oxy­phenyl group. In the crystal, inter­molecular O—H⋯O and weak C—H⋯O hydrogen bonds link mol­ecules into chains along the a axis, which are further stabilized by C—H⋯π inter­actions.

In the mol­ecular structure of the title compound, C22H27NO6, the dihydro­pyridine ring adopts a flattened boat conformation while the cyclo­hexenone ring is in an envelope conformation. In the crystal, mol­ecules stack parallel to the crystallographic a axis linked by inter­molecular N—H⋯O and C—H⋯O hydrogen bonds.

In the title compound, C19H23NO6, the 1,4-dihydro­pyridine ring is twisted slightly from planarity, with a maximum deviation of 0.101 (1) Å, and adopts a very flattened boat conformation. The dihedral angle formed between the plane through the four C atoms of the 1,4-dihydro­pyridine ring and the benzene ring is 84.67 (7)°. In the crystal structure, inter­molecular N—H⋯O and C—H⋯O hydrogen bonds link the mol­ecules into a three-dimensional network.

In the title mol­ecular salt, C18H15ClNO+·ClO4 −, the quinolin­ium ring system is approximately planar, with a maximum deviation of 0.027 (1) Å. The dihedral angle formed between the mean planes of the quinolinium ring system and the benzene ring is 78.46 (3)°. In the crystal structure, inter­molecular N—H⋯O and C—H⋯O hydrogen bonds link the cations and anions into a three-dimensional network. The crystal structure is further consolidated by C—H⋯π inter­actions.

In the title compound, C18H21NO5, the dihydro­pyridine ring adopts a flattened-boat conformation and its planar part forms a dihedral angle of 84.60 (2)° with the benzene ring. In the crystal, inter­molecular N—H⋯O and C—H⋯O hydrogen bonds result in the formation of zigzag layers parallel to (001). These layers are inter­connected via C—H⋯π inter­actions.

The title compound, C9H8N4, crystallizes with three independent mol­ecules (A, B and C) per asymmetric unit. The independent mol­ecules differ slightly in their conformations, the dihedral angles between the triazole and phenyl rings in mol­ecules A, B and C being 4.8 (2), 9.7 (2) and 7.2 (2)°, respectively. In the crystal, the independent mol­ecules are linked into a trimer by C—H⋯N hydrogen bonds.

In the title compound, C26H20ClNO2, the quinoline ring system and the methoxy­phenyl ring form dihedral angles of 69.97 (6) and 22.10 (10)°, respectively, with the propenone linkage. The 4-phenyl ring substituent on the quinoline ring system is oriented at a dihedral angle of 66.47 (3)°. In the crystal, mol­ecules exist as C—H⋯O hydrogen-bonded dimers. The structure is further stabilized by C—H⋯π inter­actions.

In the title compound, C31H24Br4N2O, one of the bromo­phenyl rings is disordered over two orientations with occupancies of 0.69 (2) and 0.31 (2). The bicyclo­[3.3.1]nonane ring system adopts a chair–boat conformation. In the crystal structure, mol­ecules are linked into chains along the c axis by inter­molecular C—H⋯O and N—H⋯O hydrogen bonds. Further stabilization is provided by C—H⋯π inter­actions.

In the title compound, C31H23ClFN3, the pyrazole ring forms dihedral angles of 72.75 (7), 18.08 (9) and 86.26 (9)° with the quinoline ring system, the phenyl ring and the fluoro­phenyl ring, respectively. In the crystal, inter­molecular C—H⋯N hydrogen bonds link the mol­ecules into chains propagating along the c axis. The crystal structure is further stabilized by C—H⋯π inter­actions.

In the title compound, C26H20ClNO2, the quinoline ring system is approximately planar with a maximum deviation of 0.028 (2) Å and forms a dihedral angle of 73.84 (5)° with the phenyl ring. Two neighbouring mol­ecules are arranged into a centrosymmetric dimer through a pair of inter­molecular C—H⋯Cl inter­actions. A pair of inter­molecular C—H⋯O hydrogen bonds link two methoxy­phenyl groups into another centrosymmetric dimer, generating an R 2 2(8) ring motif. The structure is further stabilized by C—H⋯π inter­actions.

In the title salt, C21H18ClNO, the quinoline ring system is approximately planar [maximum deviation = 0.035 (2) Å], and forms a dihedral angle of 71.42 (6)° with the attached phenyl ring. The cyclo­hexa­none ring exists in a half-boat conformation. In the crystal packing, C—H⋯O contacts link the mol­ecules into extended supra­molecular chains along the c axis.

In the title salt, C18H15ClNO+·HSO4 −, the quinolinium ring system is approximately planar, with a maximum deviation of 0.028 (2) Å, and forms a dihedral angle of 78.43 (4)° with the attached phenyl ring. A pair of inter­molecular O—H⋯O hydrogen bonds links two hydrogen sulfate anions into a dimer, generating a R 2 2(8) ring motif. Inter­molecular N—H⋯O hydrogen bonds and C—H⋯O contacts link the ions into a three-dimensional network. The structure is further stabilized by C—H⋯π inter­actions

In the title compound, C18H21NO3, the 1,4-dihydro­pyridine ring exhibits a flattened boat conformation. The methoxy­phenyl ring is nearly planar [r.m.s. deviation = 0.0723 (1) Å] and is perpendicular to the base of the boat [dihedral angle = 88.98 (4)°]. Inter­molecular N—H⋯O and C—H⋯O hydrogen bonds exist in the crystal structure.

In the title compound, C18H21NO3, which belongs to the family of calcium channel blockers, the dihydropyridine ring assumes a flattened boat conformation. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the dihydro­pyridine ring. The methoxy­phenyl ring is almost perpendicular to the prydine ring [dihedral angle = 89.01 (7)°]. In the crystal, the mol­ecules are connected by inter­molecular N—H⋯O hydrogen bonds.

In the title compound, C18H14ClNO, the quinoline ring system is approximately planar with a maximum devation of 0.022 (1) Å and forms a dihedral angle of 62.70 (3)° with the phenyl ring. In the crystal, pairs of C—H⋯O inter­molecular hydrogen bonds link neighbouring mol­ecules into inversion dimers, forming R 2 2(14) ring motifs. These inversion dimers are stacked along the b axis. The structure is further stabilized by C—H⋯π inter­actions.

In the title hydrated salt, 2NH4 +·C12H12N4O6 2−·H2O, the two hexa­hydro­pyrimidine rings in the dianion are inclined to one another at a dihedral angle of 62.76 (5)°. In the crystal structure, the anions and water mol­ecules are linked into sheets parallel to the bc plane by inter­molecular O—H⋯O hydrogen bonds and sustained by C—H⋯O contacts. The linking of the anions and water mol­ecules with the cations by N—H⋯O hydrogen bonds creates a three-dimensional extended network. The crystal structure is further stabilized by very weak C—H⋯π inter­actions.

In the title compound, C20H25NO4, the 1,4-dihydro­pyridine ring adopts a flattened-boat conformation and forms a dihedral angle of 89.77 (8)° with the benzene ring. Inter­molecular N—H⋯O hydrogen bonds result in the formation of extended chains parallel to the b axis.

In the title mol­ecule, C19H23NO5, the dihedral angle formed by the benzene ring and the planar part of the dihydro­pyridine ring is 83.52 (5)°. The dihydro­pyridine ring adopts a flattened boat conformation. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds, generating chains running parallel to [100]. The crystal structure is consolidated by C—H⋯O contacts.

In the title compound, C21H27NO5, the dihydropyridine ring adopts a boat conformation. The ethoxy­phenyl ring is oriented approximately perpendicular to the planar part of the dihydropyridine ring, making a dihedral angle of 89.45 (6)°. An intra­molecular C—H⋯O hydrogen bond generates an S(6) ring motif. In the crystal structure, neighbouring mol­ecules are linked into chains along the a axis by N—H⋯O hydrogen bonds and the chains are inter­connected into two-dimensional networks parallel to the ab plane by C—H⋯O hydrogen bonds. The structure is further stabilized by weak C—H⋯π inter­actions.

In the title compound, C23H26O3, the three six-membered rings of the xanthene system are non-planar, having total puckering amplitudes, Q T, of 0.443 (2), 0.202 (2) and 0.449 (2) Å. The central ring adopts a boat conformation and the outer rings adopt sofa conformations. The crystal structure is stabilized by van der Waals inter­actions.