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1.  2-(4-Chloro­phen­yl)-2-oxoethyl naphthalene-1-carboxyl­ate 
In the title compound, C19H13ClO3, an ester of 1-naphthoic acid with an aromatic alcohol, the least-squares planes defined by the C atoms of the respective aromatic systems enclose an angle of 77.16 (3)°. In the crystal, C—H⋯O contacts connect the mol­ecules into undulating sheets parallel to the bc plane.
doi:10.1107/S1600536813006958
PMCID: PMC3629603  PMID: 23634090
2.  2,4-Dichloro­benzyl 2-meth­oxy­benzoate 
In the title compound, C15H12Cl2O3, the aromatic rings make a dihedral angle of 10.78 (4)°. In the molecule, there is a short C—H⋯O contact. In the crystal, C—H⋯O contacts connect the mol­ecules into C(7)C(8) chains along the b axis. The shortest inter­centroid distance between two benzoic acid aromatic systems is 3.7416 (8) Å.
doi:10.1107/S1600536813006156
PMCID: PMC3629538  PMID: 23634056
3.  Ethyl 4-({1-[2-(4-bromo­phen­yl)-2-oxo­eth­yl]-1H-1,2,3-triazol-4-yl}meth­oxy)-8-(trifluoro­meth­yl)quinoline-3-carboxyl­ate 
The title compound, C24H18BrF3N4O4, is a 1,2,3-triazole derivative featuring, among others, a quinoline-derived substituent. In the crystal, C—H⋯O, C—H⋯N and C—H⋯F contacts connect the mol­ecules into a three-dimensional network. The shortest centroid–centroid distance between two aromatic systems is 3.896 (2) Å and is found between the two different six-membered rings of the quinoline scaffold in neighbouring mol­ecules.
doi:10.1107/S1600536812046417
PMCID: PMC3588982  PMID: 23476218
4.  Ethyl 3-(2-eth­oxy-2-oxoeth­oxy)-6-(tri­fluoro­meth­yl)furo[3,2-c]quinoline-2-carboxyl­ate 
In the title compound, C19H16F3NO6, a quinoline derivative featuring an annealated furan substituent, the mean planes of the carb­oxy substituents are at an angle of 74.3 (2)°. In the crystal, C—H⋯O contacts result in undulating chains along [110]. C—H⋯F contacts also occur. The shortest centroid–centroid distance between rings is 3.3376 (7) Å, involving two furan rings of neighbouring mol­ecules.
doi:10.1107/S1600536812046843
PMCID: PMC3588983  PMID: 23476219
5.  Ethyl 4-oxo-8-trifluoro­methyl-1,4-dihydro­quinoline-3-carboxyl­ate 
The asymmetric unit of the title compound, C13H10F3NO3, contains two independent mol­ecules with similar conformations. In the crystal, N—H⋯O hydrogen bonds link alternating independent mol­ecules into chains in [-110]. In the chain, the quinoline planes of the independent mol­ecules are almost perpendicular to each other, forming a dihedral angle of 89.8 (1)°. π–π inter­actions between the aromatic rings of quinoline bicycles related by inversion centres [for two independent centrosymmetric dimers, the shortest centroid–centroid distances are 3.495 (1) and 3.603 (1) Å] link the hydrogen-bonded chains into layers parallel to (110). Weak C—H⋯F and C—H⋯O inter­actions further consolidate the crystal packing.
doi:10.1107/S1600536812045321
PMCID: PMC3588845  PMID: 23468810
6.  3-(4-Chloro­phen­yl)-5-phenyl-4,5-di­hydro-1,3-oxazole 
In the title compound, C15H12ClNO, the isoxazoline ring adopts an envelope conformation with the C atom bearing an unsubstituted phenyl ring as the flap atom. The chlorinated phenyl group is nearly in-plane with the four coplanar atoms of the heterocycle and the corresponding mean planes enclosing an angle of 1.16 (7)°. The unsubstituted phenyl group attached to the envelope flap atom approaches a nearly perpendicular orientation relative to the isoxazoline ring with a dihedral angle of 74.93 (7)°. In the crystal, weak C—H⋯O, C—H⋯N and C—H⋯π inter­actions connect the mol­ecules into layers perpendicular to the a axis.
doi:10.1107/S1600536812043711
PMCID: PMC3515301  PMID: 23284521
7.  Ethyl (Z)-3-(4-methyl­anilino)-2-[(4-methyl­phen­yl)carbamo­yl]prop-2-enoate 
The title compound, C20H22N2O3, is a secondary amine featuring an amide and an ester functionality in connection with a Michael system. The conformation about the C=C bond is E. Intra­molecular N—H⋯O hydrogen bonds occur. In the crystal, C—H⋯O contacts connect the mol­ecules into chains along the b-axis direction.
doi:10.1107/S1600536812043723
PMCID: PMC3515303  PMID: 23284523
8.  Ethyl 4-{[1-(2,4-dichloro­benz­yl)-1H-1,2,3-triazol-4-yl]meth­oxy}-8-(trifluoro­meth­yl)quinoline-3-carboxyl­ate 
In the title compound, C23H17Cl2F3N4O3, the triazole ring makes dihedral angles of 50.27 (6) and 82.78 (7)° with the quinoline ring system and the dichloro-substituted benzene ring. The dihedral angle between the quinoline and dichloro-substituted benzene rings is 38.17 (4)°. In the crystal, mol­ecules are linked via C—H⋯N, C—H⋯F and C—H⋯O hydrogen bonds into a three-dimensional network. The crystal is further consolidated by C—H⋯π contacts to the triazole ring and inversion-related π–π inter­actions between the benzene and pyridine rings of quinoline systems [centroid–centroid distance = 3.7037 (7) Å].
doi:10.1107/S1600536812039633
PMCID: PMC3470374  PMID: 23125787
9.  Dimethyl 4-[3-(4-meth­oxy­phen­yl)-1-phenyl-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate dihydrate 
In the title compound, C27H27N3O5·2H2O, the dihydro­pyridine ring adopts a flattened boat conformation. The central pyrazole ring is essentially planar [maximum deviation of 0.003 (1) Å] and makes dihedral angles of 50.42 (6) and 26.44 (6)° with the benzene rings. In the crystal, mol­ecules are linked via N—H⋯O, O—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds into two-dimensional networks parallel to the bc plane. The crystal structure is further consolidated by weak C—H⋯π inter­actions.
doi:10.1107/S1600536812027936
PMCID: PMC3394006  PMID: 22798871
10.  2-(4-Bromo­phen­yl)-2-oxoethyl anthracene-9-carboxyl­ate 
In the title compound, C23H15BrO3, the anthracene ring system is essentially planar [maximum deviation = 0.29 (2) Å] and makes a dihedral angle of 5.74 (8)° with the mean plane of the bromo-substituted benzene ring. An intra­molecular C—H⋯O hydrogen bond generates an S(9) ring motif. In the crystal, mol­ecules are linked by C—H⋯O inter­actions, forming a two-dimensional network parallel to the ac plane. π–π stacking inter­actions are observed between benzene rings [centroid–centroid distances = 3.5949 (14) and 3.5960 (13) Å].
doi:10.1107/S1600536812022684
PMCID: PMC3379439  PMID: 22719637
11.  2-(4-Fluoro­phen­yl)-2-oxoethyl 2-methoxy­benzoate 
In the title compound, C16H13FO4, the aromatic rings enclose an angle of 73.68 (6)°. In the crystal, C—H⋯O and C—H⋯F contacts connect the mol­ecules into a three-dimensional network. The shortest inter­centroid distance between two aromatic π-systems is 3.6679 (7) Å and is apparent between the fluorinated phenyl groups.
doi:10.1107/S1600536812002577
PMCID: PMC3275257  PMID: 22347113
12.  Diethyl 2-{[2-(trifluoro­meth­yl)anil­ino]methyl­idene}propane­dioate 
The title compound, C15H16F3NO4, is an N-substituted derivative of ortho-trifluoro­methyl­aniline featuring a twofold Michael system. The least-squares planes defined by the atoms of the phenyl ring and the atoms of the Michael system enclose an angle of 15.52 (5)°. Apart from classical intra­molecular N—H⋯O and N—H⋯F hydrogen bonds, inter­molecular C—H⋯O contacts are observed, the latter connecting the mol­ecules into chains along [110]. The shortest inter­centroid distance between two aromatic systems is 3.6875 (9) Å.
doi:10.1107/S1600536812002590
PMCID: PMC3275258  PMID: 22347114
13.  Ethyl 1-(2,4-dichloro­benz­yl)-4-oxo-7-trifluoro­meth­yl-1,4-dihydro­quinoline-3-carboxyl­ate 
In the title compound, C20H14Cl2F3NO3, the trifluromethyl group is disordered over two sets of sites in a 0.784 (10):0.216 (10) ratio. The quinoline ring system is essentially planar with a maximum deviation of 0.058 (2) Å for the N atom and forms dihedral angles of 89.23 (11) and 8.13 (17)°, respectively with the mean planes of the benzene ring and the carboxyl­ate group. In the crystal, pairs of weak C—H⋯O and C—H⋯F hydrogen bonds link mol­ecules into centrosymmetric dimers. The crystal structure is further stabilized by weak π–π [centroid–centroid distance = 3.624 (2) Å] inter­actions.
doi:10.1107/S1600536812001249
PMCID: PMC3275192  PMID: 22347048
14.  2-(4-Fluoro­phen­yl)-2-oxoethyl 4-meth­oxy­benzoate 
In the title compound, C16H13FO4, the dihedral angle between the benzene rings is 84.28 (8)°. In the crystal, C—H⋯F and C—H⋯O hydrogen bonds link the mol­ecules to form a three-dimensional network. The crystal structure is consolidated by C—H⋯π inter­actions and short F⋯F contacts [2.7748 (14) Å] also occur.
doi:10.1107/S1600536811049233
PMCID: PMC3239086  PMID: 22199934
15.  2-(2,4-Dichloro­phen­yl)-2-oxoethyl 4-meth­oxy­benzoate 
In the title compound, C16H12Cl2O4, the dihedral angle between the benzene rings is 70.11 (6)°. In the crystal, mol­ecules are linked by C—H⋯O hydrogen bonds into a three-dimensional network. A C—H⋯π inter­action is also observed.
doi:10.1107/S1600536811048720
PMCID: PMC3239022  PMID: 22199870
16.  2-(4-Bromo­phen­yl)-2-oxoethyl 4-methyl­benzoate 
The title compound, C16H13BrO3, consists of a toluene ring and a bromo­benzene ring which are linked together by a 2-oxopropyl acetate group. The dihedral angle formed between the toluene and bromo­benzene rings is 80.70 (7)°. In the crystal, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into a three-dimensional network.
doi:10.1107/S1600536811045272
PMCID: PMC3238827  PMID: 22199680
17.  4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline 
In the title compound, C23H20F3N5O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61 (11), 49.94 (12) and 42.58 (14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra­molecular C—H⋯O hydrogen bond generates an S(7) ring motif. In the crystal, mol­ecules are linked into infinite chains along the b axis by C—H⋯N hydrogen bonds.
doi:10.1107/S1600536811044370
PMCID: PMC3247502  PMID: 22220120
18.  2-(4-Bromo­phen­yl)-2-oxoethyl 2-methyl­benzoate 
In the title compound, C16H13BrO3, the dihedral angle formed between the bromo- and methyl-substituted benzene rings is 66.66 (8)°. In the crystal, mol­ecules are linked by inter­molecular C—H⋯O hydrogen bonds, forming a two-dimensional network parallel to the ac plane. The crystal packing is further consolidated by C—H⋯π inter­actions.
doi:10.1107/S1600536811044564
PMCID: PMC3247503  PMID: 22220121
19.  2-(4-Chloro­phen­yl)-2-oxoethyl 4-methyl­benzoate 
In the title compound, C16H13ClO3, the dihedral angle between the benzene rings is 80.74 (8)°. In the crystal, C—H⋯O hydrogen bonds link the mol­ecules to form C(11) chains propagating in [010].
doi:10.1107/S1600536811042851
PMCID: PMC3247425  PMID: 22220043
20.  2-(4-Fluoro­phen­yl)-2-oxoethyl 3-(trifluoro­meth­yl)benzoate 
In the title compound, C16H10F4O3, the fluoro­form group is disordered over two orientations with an occupancy ratio of 0.834 (4):0.166 (4). The dihedral angle between the two aromatic rings is 20.34 (9)°. In the crystal, C—H⋯O hydrogen bonds link the mol­ecules into layers lying parallel to the bc plane.
doi:10.1107/S160053681103947X
PMCID: PMC3247575  PMID: 22219880
21.  2-(4-Bromo­phen­yl)-2-oxoethyl 4-hy­droxy­benzoate 
In the title compound, C15H11BrO4, the dihedral angle between the aromatic rings is 66.77 (8)°. In the crystal, O—H⋯O, C—H⋯Br and C—H⋯O hydrogen bonds link the mol­ecules, forming layers lying parallel to (101). The crystal packing is further consolidated by C—H⋯π inter­actions and π–π stacking inter­actions [centroid–centroid distance = 3.5476 (7) Å].
doi:10.1107/S1600536811040311
PMCID: PMC3247591  PMID: 22219896
22.  2-(4-Chloro­phen­yl)-2-oxoethyl 4-hy­droxy­benzoate 
The title compound, C15H11ClO4, consists of a chloro­benzene ring and a phenol ring which are linked together by a 1,4-dioxo-2-oxabutane-1,4-diyl group. The dihedral angle between the chloro­benzene and phenol rings is 65.70 (11)°. In the crystal, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into chains along [010].
doi:10.1107/S1600536811037500
PMCID: PMC3201459  PMID: 22065030
23.  2-(4-Chloro­phen­yl)-2-oxoethyl benzoate 
In the title compound, C15H11ClO3, the dihedral angle between the aromatic rings is 84.29 (8)°. In the crystal, mol­ecules are linked by weak C—H⋯π inter­actions.
doi:10.1107/S160053681102383X
PMCID: PMC3151803  PMID: 21837175
24.  2-(4-Bromo­phen­yl)-2-oxoethyl 4-chloro­benzoate 
The asymmetric unit of the title compound, C15H10BrClO3, consists of three crystallographically independent mol­ecules. The dihedral angles between the benzene rings in the three mol­ecules are 68.8 (2), 0.7 (3) and 66.1 (2)°. In the crystal, the three independent mol­ecules are inter­connected by C—H⋯O hydrogen bonds, leading to isolated trimers.
doi:10.1107/S1600536811022963
PMCID: PMC3151903  PMID: 21837113
25.  2-(4-Chloro­phen­yl)-2-oxoethyl 2-meth­oxy­benzoate 
In the title compound, C16H13ClO4, the two benzene rings make a dihedral angle of 86.38 (8)°. In the crystal, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules to form columns along the a axis. The mol­ecules are also stabilized by a π–π stacking inter­action, with a centroid–centroid distance of 3.7793 (10) Å between the inversion-related benzene rings.
doi:10.1107/S1600536811021246
PMCID: PMC3151969  PMID: 21837084

Results 1-25 (31)