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issn:2229-340
1.  PREVALENCE OF ANTIBODIES TO HUMAN PARVOVIRUS B19 IN SAUDI WOMEN OF CHILDBEARING AGE IN MAKKAH 
Objectives:
To determine the seroprevalence rate of immunoglobulin G (IgG) and immunoglobulin M (IgM) to parvovirus B19 in pregnant Saudi women in Makkah.
Subjects and Methods:
Using enzyme-linked immunosorbent assay (ELISA), a total of 1200 serum samples were tested for antibodies to parvovirus B19 known to cause a variety of clinical syndromes in women and newborn infants.
Results:
Parvovirus B19 IgG antibodies detected in 46.6% and IgM antibodies were found in 2.25% of different age groups.
Conclusion:
The previous exposure to parvovirus B19 was determined, and 560 (46.6%) of 1200 pregnant Saudi women tested at their first antenatal visit were seropositive for specific IgG. The rate of maternal infection in susceptible pregnancies was 2.25%. These results were in accordance with previous studies performed in other countries.
PMCID: PMC3410113  PMID: 23012138
Makkah; Saudi Arabia; pregnant women; parvovirus B19; ELISA
2.  SEROPOSITIVITY OF CHLAMYDIA TRACHOMATIS AMONG SAUDI PREGNANT WOMEN IN MAKKAH 
Objective:
To determine the seroprevalence rates of immunoglobulin G (IgG) and immunoglobulin M (IgM) to Chlamydia trachomatis in Saudi pregnant women.
Subjects and Methods:
Using enzyme-linked immunosorbent assay (ELISA), a total of 1600 serum samples were tested for antibodies to Chlamydia trachomatis known to cause a variety of clinical syndromes in women and newborn infants.
Results:
Chlamydia trachomatis IgG antibodies were detected in 8.7% and IgM antibodies were found in 1.5% of different age groups.
Conclusion:
Pregnant Saudi women have low prevalence rate of Chlamydia trachomatis IgG antibodies and lower prevalence for Chlamydia trachomatis IgM.
PMCID: PMC3410065  PMID: 23012106
Makkah; Pregnant women; ELISA; Saudi Arabia; Chlamydia trachomatis
3.  A STUDY OF GROUP A STREPTOCOCCAL BACTERIA ISOLATION FROM CHILDREN LESS THAN 12 YEARS WITH ACUTE TONSILLITIS, PHARYNGITIS AND HEALTHY PRIMARY SCHOOL CHILDREN 
Aim:
This study was carried out to assess the prevalence of Group A Streptococcal (GAS) bacteria in the throat specimens of children with tonsillitis and pharyngitis compared to healthy children of the same age group.
Methodology:
The study was a prospective one. Throat swabs were obtained from 73 children aged 1-12 years diagnosed with acute tonsillitis and pharyngitis (sore throat and pyrexia >38.5°C) visiting a pediatric outpatient clinic between December, 1999 and April, 2000. In the same period throat swabs were obtained from 465 healthy primary school children aged 6-12 years. GAS from patients was tested for sentivity to penicillin, erythromycin, and cefaclor.
Results:
In children with tonsillitis and pharyngitis GAS was found in 29 out of 73 (40%). In healthy school children GAS was found in 15 out of 465 (3%).In the patients group GAS was sensitive to penicillin in 14(48%), erythromycin in 27(93%), and cefaclor in 28(96%)
Conclusion:
Although the prevalence of GAS among healthy children was similar to international studies, the GAS infection was high among children with acute tonsillitis and pharyngitis. Sensitivity to penicillin was less than 50% and more than 90% for erythromycin and cefaclor. We recommend routine throat swab for children with acute tonsillitis and pharyngitis and the proper treatment of GAS positive patients to prevent further complications.
PMCID: PMC3430181  PMID: 23008668
Group A streptococcus; tonsillitis; pharyngitis; antibiotic sensitivity; healthy; school children; Saudi Arabia

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