PMCC PMCC

Search tips
Search criteria

Advanced
Results 1-2 (2)
 

Clipboard (0)
None
Journals
Authors
Year of Publication
Document Types
issn:1757-594
1.  HIV vaccination: turning the spotlight on effector memory T cells as mucosal gatekeepers 
F1000 biology reports  2009;1(89):nihpa161827.
The accumulating failures in HIV vaccine development demonstrate that the immunization approaches used so far are insufficient to reproduce the naturally occurring immunity that controls the virus in long-term non-progressors, HIV controllers, and continuously exposed sex workers. They also underscore the desperate need for new approaches in the design of more effective vaccination protocols. Recent findings might have brought us closer to that goal by providing proof of concept for a novel preventative HIV vaccine by establishing CD8 effector memory T cells within the mucosal sites of transmission.
doi:10.3410/B1-89
PMCID: PMC2799925  PMID: 20046812
2.  HIV vaccination: turning the spotlight on effector memory T cells as mucosal gatekeepers 
The accumulating failures in HIV vaccine development demonstrate that the immunization approaches used so far are insufficient to reproduce the naturally occurring immunity that controls the virus in long-term non-progressors, HIV controllers, and continuously exposed sex workers. They also underscore the desperate need for new approaches in the design of more effective vaccination protocols. Recent findings might have brought us closer to that goal by providing proof of concept for a novel preventative HIV vaccine by establishing CD8 effector memory T cells within the mucosal sites of transmission.
doi:10.3410/B1-89
PMCID: PMC2799925  PMID: 20046812

Results 1-2 (2)