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1.  Methodological Issues in Exercise Intervention Research in Oncology 
Seminars in oncology nursing  2007;23(4):297-304.
Objectives
To review randomized controlled trials (RCTs) that offered exercise interventions for adults diagnosed and treated for cancer related to design, sample, type of intervention and outcomes.
Data sources
Several electronic data-bases were searched and recent review papers were scanned to identify relevant publications.
Conclusion
Exercise adoption seems clearly feasible for early-stage cancer patients, particularly breast cancer patients. Data support positive effects for physical functioning, quality of life (QOL), and psychological well-being. Effects for patients with later-stage disease and other cancers are less clear. The impact of exercise adoption on biomarkers of disease status, immune functioning and hormone levels should also be examined.
Implications for nursing practice
There are many opportunities for nurses to promote exercise in clinical care and in a research context.
doi:10.1016/j.soncn.2007.08.006
PMCID: PMC2180155  PMID: 18022057
2.  Managing the Early and Locally Advanced Breast Cancer Patient at High Risk for Recurrence: Recent Advances and Nursing Implications 
Seminars in oncology nursing  2007;23(1):29-36.
OBJECTIVES
To identify breast cancer patients at high risk for recurrence.
To describe current evidence for clinical management of early and locally advanced breast cancer and integrate this knowledge into nursing practice.
DATA SOURCES
Articles, abstracts, and practice guidelines.
CONCLUSION
Recent clinical trials have integrated the biology of breast cancer into individualized systemic therapy. Risk-adjusted treatment is driven by the addition of taxane therapy to systemic therapy, aromatase inhibitors and perhaps most markedly, trastuzumab into adjuvant therapy strategies.
IMPLICATIONS FOR NURSING PRACTICE
The decision to initiate systemic adjuvant therapy requires knowledge of risk of relapse, integration of evidence from clinical trials, and facilitation of patient decision making.
doi:10.1016/j.soncn.2006.11.005
PMCID: PMC1880870  PMID: 17303514

Results 1-2 (2)