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Seminars in Oncology Nursing  2012;28(2):129-138.
To review the evidence on a number of biomarkers that show potential clinical utility in the prediction of and treatment responsiveness for the four most common symptoms associated with cancer and its treatment (i.e., pain, fatigue, sleep disturbance, depression).
Data Sources
Review and synthesis of review articles and data-based publications.
A growing body of evidence suggests that sensitive and specific biomarkers will be available to assist clinicians with the assessment and management of symptoms.
Implications for Practice
Nurses will play a critical role in educating patients about their risk for specific symptoms based on an evaluation of specific biomarkers. Nurses will be involved in using biomarker data to titrate medications based on patient’s responses to symptom management interventions.
PMCID: PMC3340583  PMID: 22542321
biomarkers; genomics; pain; fatigue; depression; sleep disturbance; symptoms; quality of life
2.  Psychological Health in Cancer Survivors 
Seminars in Oncology Nursing  2008;24(3):193-201.
The prevalence of both negative (distress) and positive responses (growth, well-being) to the cancer experience is examined and difficulties in establishing the prevalence of these responses discussed. A conceptual framework for understanding factors associated with psychological health in cancer survivors is presented. Finally, strategies for promoting psychological health in cancer survivors are examined.
Data Sources
Review of the literature.
Psychological health in cancer survivors is defined by the presence or absence of distress as well as the presence or absence of positive well-being and psychological growth. Furthermore, psychological health in cancer survivors is determined by the balance between two classes of factors: the stress and burden posed by the cancer experience and the resources available for coping with this stress and burden.
Implications for nursing practice
In general, promotion of psychological health is based upon the prevention or treatment of distress as well as the encouragement of growth and well-being. Periodic screening for psychological distress across the cancer trajectory is critical to appropriate management of distress.
PMCID: PMC3321244  PMID: 18687265
3.  Clinical Trials – The Art of Enrollment 
Seminars in Oncology Nursing  2008;24(4):262-269.
Enrollment barriers and multidisciplinary approaches to increase cancer trials participation are presented. Recruitment barriers, research in Maryland, and a Best Practice for cancer trials are discussed.
Data Sources
Journal and research articles, web sites.
Clinical trials have produced prevention and care advances for cancer and other diseases. Trial enrollment is lower for minorities and underserved communities. A comprehensive program for addressing enrollment barriers should incorporate research on barriers, multidisciplinary teams, and education and trial infrastructure in community settings.
Implications for Nursing Practice
Health disparities training, including culturally appropriate enrollment approaches for education and retention of underserved communities, should incorporate community stakeholders and nurse/physician researchers.
PMCID: PMC3262589  PMID: 19000600
clinical trials enrollment; barriers; accrual; minority and underserved

Results 1-3 (3)