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1.  Managing the Early and Locally Advanced Breast Cancer Patient at High Risk for Recurrence: Recent Advances and Nursing Implications 
Seminars in oncology nursing  2007;23(1):29-36.
OBJECTIVES
To identify breast cancer patients at high risk for recurrence.
To describe current evidence for clinical management of early and locally advanced breast cancer and integrate this knowledge into nursing practice.
DATA SOURCES
Articles, abstracts, and practice guidelines.
CONCLUSION
Recent clinical trials have integrated the biology of breast cancer into individualized systemic therapy. Risk-adjusted treatment is driven by the addition of taxane therapy to systemic therapy, aromatase inhibitors and perhaps most markedly, trastuzumab into adjuvant therapy strategies.
IMPLICATIONS FOR NURSING PRACTICE
The decision to initiate systemic adjuvant therapy requires knowledge of risk of relapse, integration of evidence from clinical trials, and facilitation of patient decision making.
doi:10.1016/j.soncn.2006.11.005
PMCID: PMC1880870  PMID: 17303514

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