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1.  Randomised controlled trial assessing the effectiveness of a booklet on the duration of breast feeding 
Archives of Disease in Childhood  1997;76(6):500-504.
Accepted 14 February 1997

OBJECTIVE—To test the efficacy of an information booklet to increase the duration of breast feeding.
RESEARCH DESIGN—Randomised design, stratifying by maternal residence and working activity. Two hundred women were recruited, 103 received the booklet and verbal counselling and 97 verbal counselling only.
POPULATION—Infants observed from 15 September 1993 to 15 June 1994 in the well baby outpatient clinic of the Paediatric Institute of the Catholic University of Rome, Italy.
MAIN RESULTS—No statistically significant difference was found between the two groups in the prevalence of exclusive or complementary breast feeding at 6 months of age: 48.5% and 59.2% in the intervention group, 43.7% and 51.5% in the control group. The median duration of exclusive or complementary breast feeding was 24 and 27 weeks in the treated group, 22 and 25 in the control group.
CONCLUSIONS—The information booklet alone does not seem to increase the duration and the prevalence of breast feeding at 6 months of age. The use of written material with a more individualised support and more extensive use of randomised clinical trials in the evaluation of health promoting programmes is recommended. 


PMCID: PMC1717207  PMID: 9245846
5.  Representation of cloned genomic sequences in two sequencing vectors: correlation of DNA sequence and subclone distribution. 
Nucleic Acids Research  1997;25(15):2960-2966.
Representation of subcloned Caenorhabditis elegans and human DNA sequences in both M13 and pUC sequencing vectors was determined in the context of large scale genomic sequencing. In many cases, regions of subclone under-representation correlated with the occurrence of repeat sequences, and in some cases the under-representation was orientation specific. Factors which affected subclone representation included the nature and complexity of the repeat sequence, as well as the length of the repeat region. In some but not all cases, notable differences between the M13 and pUC subclone distributions existed. However, in all regions lacking one type of subclone (either M13 or pUC), an alternate subclone was identified in at least one orientation. This suggests that complementary use of M13 and pUC subclones would provide the most comprehensive subclone coverage of a given genomic sequence.
PMCID: PMC146865  PMID: 9224593

Results 1-7 (7)