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1.  Hyperphosphataemia after enemas in childhood: prevention and treatment. 
Archives of Disease in Childhood  1993;68(2):233-234.
The case of a child with severe hyperphosphataemia and symptomatic hypocalcaemia secondary to retention of phosphate administered through an antegrade continence enema is reported. Caution should be exercised with the use of phosphate enemas and prompt action taken to remedy retention. The use of glucose with insulin in the emergency management of acute hyperphosphataemia is discussed.
PMCID: PMC1029243  PMID: 8481047
2.  Antenatal diagnosis of abdominal wall defects: a missed opportunity? 
Archives of Disease in Childhood  1990;65(7 Spec No):687-689.
A review of six years' experience with antenatal diagnosis of abdominal wall defects by ultrasound showed its impact to be limited by poor detection rates. Twenty infants with exomphalos and 20 with gastroschisis were recorded but only 25 (63%) were diagnosed antenatally. The ultrasound false negative rate was higher for exomphalos (35%) than for gastroschisis (22%). No difference was detected in the incidence of associated abnormalities, premature gestation, primary closure rate, or mortality between the antenatally and postnatally diagnosed groups for either exomphalos or gastroschisis. Antenatal diagnosis of gastroschisis has little effect on management but allows parental counselling and in utero transfer. The frequency of concomitant abnormalities in exomphalos profoundly affects prognosis and the detection of these is the major role of antenatal diagnosis in this condition. Failure to detect abdominal wall defects by ultrasound may be a reflection of technique or equipment, but some gastroschisis may be of perinatal onset and not detectable antenatally.
PMCID: PMC1590182  PMID: 2143644
3.  Quantitative bacterial flora of acute appendicitis. 
Archives of Disease in Childhood  1988;63(5):536-540.
A quantitative bacteriological study of the appendix wall of 43 children admitted to this unit showed no significant differences between the flora of the histologically normal and acutely inflamed appendices. Bacteroides species, Escherichia coli, and streptococcal species were the commonest organisms isolated and were found in counts of 10(3) to 10(8) organisms per gram of tissue. Bacteroides species were most commonly the dominant flora in both normal and inflamed appendices. The lack of increased counts of organisms in acute inflammation of the appendix suggests an unfavourable environment to bacterial proliferation making primary bacterial infection an unlikely aetiological factor in the pathogenesis of appendicitis.
PMCID: PMC1778900  PMID: 3389871
4.  Micro-organisms in gastroenteritis. 
Archives of Disease in Childhood  1984;59(9):848-855.
We present bacteriological and virological findings together with salient clinical features from a prospective study of 447 children aged under 2 years admitted to hospital with infectious gastroenteritis. Putative pathogenic micro-organisms were identified in the stools of 75% of these children. Eight identifiably distinct groups of viruses, found on electron microscopy and tissue culture were present in 67% of patients--rotavirus was detected most frequently. Pathogenic bacteria (salmonellas, shigellas, Escherichia coli, and Campylobacter jejuni--but excluding Clostridium difficile) were found in 16% only. Altogether 4 X 9% of 390 patients had gastroenteritis associated with Cl difficile toxin. The mean duration of diarrhoea was shortest in patients with identifiable virus, with rotavirus having a mean of 5 X 01 days, and was longest in patients with pathogenic bacteria in the stools (11 X 14 days). The finding of more than one type of virus did not seem to be associated with a significantly increased duration of diarrhoea. There are few clinical features which can be associated specifically with any particular micro-organism or groups of these. Multiple organism isolation was common, but the severity of the illness in those patients with at least two types of organism was not greater. Certain viruses, including the norwalk-like virus, known to be associated with outbreaks of gastroenteritis were found as frequently in a group of patients who did not have diarrhoea studied for comparison. Virus was still detectable in the stools of up to 40% of asymptomatic children on the day of discharge.
PMCID: PMC1628695  PMID: 6091568
5.  Myotonic dystrophy and bonding failure. 
Archives of Disease in Childhood  1979;54(10):807-808.
PMCID: PMC1545657  PMID: 507908
7.  Sex-linked Hydrocephalus 
Archives of Disease in Childhood  1961;36(189):481-485.
PMCID: PMC2012797  PMID: 13889294
8.  Paraplegia and mongolism in twins 
Archives of Disease in Childhood  1938;13(73):79-84.
PMCID: PMC1975557  PMID: 21032097

Results 1-8 (8)