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1.  DWI PREDICTS FUTURE PROGRESSION TO ALZHEIMER’S DISEASE IN AMNESTIC MILD COGNITIVE IMPAIRMENT 
Neurology  2005;64(5):902-904.
This study tests if measures of hippocampal water diffusivity at baseline can predict future progression to Alzheimer’s Disease (AD) in amnestic mild cognitive impairment (aMCI). Higher baseline hippocampal diffusivity was associated with a greater hazard of progression to AD in aMCI (p=0.002). MR diffusion weighted imaging (DWI) may help identify patients with aMCI who will progress to AD as well or better than structural MRI measures of hippocampal atrophy.
doi:10.1212/01.WNL.0000153076.46126.E9
PMCID: PMC2771335  PMID: 15753434

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