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Journals
Year of Publication
4.  Eleven Levels of Spinous Process Fractures in Thoracolumbar Spine 
Asian Spine Journal  2014;8(6):852-855.
Cases of over 5-level spinous process fractures are extremely rare. Thoracolumbar region of spine is superimposed on ribs; and as such additional studies such as computerized tomography are needed to diagnose fractures in this region. We report a case of 11 contiguous level thoracolumbar spinous process fractures, which has been treated conservatively.
doi:10.4184/asj.2014.8.6.852
PMCID: PMC4278995  PMID: 25558332
Multilevel spinous process fractures; Thoracolumbar spine
6.  Comment on: Sciatica in the Young 
Asian Spine Journal  2014;8(5):704.
doi:10.4184/asj.2014.8.5.704
PMCID: PMC4206825  PMID: 25346828
9.  Sciatica in the Young 
Asian Spine Journal  2014;8(5):703.
doi:10.4184/asj.2014.8.5.703
PMCID: PMC4206824  PMID: 25346827
11.  Giant Chordoma of the Upper Thoracic Spine with Mediastinal Involvement: A Surgical Challenge 
Asian Spine Journal  2014;8(3):353-356.
Thoracic chordomas are very rare malignant tumours originating from notochordal remnants. These tumours develop within a vertebral body and enlarge involving the mediastinal compartment. Because of their slow-growing attitude, they become symptomatic only when they invade or compress the spinal cord and/or mediastinal organs. We present a rare case of a thoracic spine chordoma presenting with increasing paraparesis with a huge mediastinal component which was surgically debulked to decompress the spinal cord and medistinal organs.
doi:10.4184/asj.2014.8.3.353
PMCID: PMC4068856  PMID: 24967050
Chordoma; Spine; Bone neoplasms; Mediastinum; Surgery
12.  Management of Pyogenic Discitis 
Asian Spine Journal  2014;8(3):391.
doi:10.4184/asj.2014.8.3.391
PMCID: PMC4068862  PMID: 24967056
13.  Answer to the Topic "Management of Pyogenic Discitis" 
Asian Spine Journal  2014;8(3):392.
doi:10.4184/asj.2014.8.3.392
PMCID: PMC4068863  PMID: 24967057
14.  Cervical Perineural Cyst Masquerading as a Cervical Spinal Tumor 
Asian Spine Journal  2014;8(2):202-205.
Tarlov (perineural) cysts of the nerve roots are common and usually incidental findings during magnetic resonance imaging of the lumbosacral spine. There are only a few case reports where cervical symptomatic perineural cysts have been described in the literature. We report such a case where a high cervical perineural cyst was masquerading as a cervical spinal tumor.
doi:10.4184/asj.2014.8.2.202
PMCID: PMC3996346  PMID: 24761204
Tarlov's cysts; Perineural cyst; Spinal cyst; spine; Cervical spine
15.  Tuberculosis of Sacrum 
Asian Spine Journal  2014;8(1):112.
doi:10.4184/asj.2014.8.1.112
PMCID: PMC3939363  PMID: 24596614
18.  Osteoblastoma of C2 Corpus: 4 Years Follow-up 
Asian Spine Journal  2012;6(2):136-139.
Osteoblastomas are rare neoplasms of the spine. The majority of the spinal lesions arise from the posterior elements and involvement of the corpus is usually by extension through the pedicles. An extremely rare case of isolated C2 corpus osteoblastoma is presented herein. A 9-year-old boy who presented with neck pain and spasmodic torticollis was shown to have a lesion within the corpus of C2. He underwent surgery via an anterior cervical approach and the completely-resected mass was reported to be an osteoblastoma. The pain resolved immediately after surgery and he had radiologic assessments on a yearly basis. He was symptom-free 4 years post-operatively with benign radiologic findings. Although rare, an osteoblastoma should be considered in the differential diagnosis of neck pain and torticollis, especially in patients during the first two decades of life. The standard treatment for osteoblastomas is radical surgical excision because the recurrence rate is high following incomplete resection.
doi:10.4184/asj.2012.6.2.136
PMCID: PMC3372549  PMID: 22708018
Osteoblastoma; Osteoid osteoma; C2 corpus; Anterior cervical approach
19.  Focal Ligamentum Flavum Hypertrophy with Ochronotic Deposits: An Unusual Cause for Neurogenic Claudication in Alkaptonuria 
Asian Spine Journal  2012;6(2):148-151.
Neurogenic claudication resulting from focal hypertrophy of the ligamentum flavum in the lumbar spine due to ochronotic deposits has not been reported till date. The authors discuss one such case highlighting the pathogenesis, histological and radiological features. Salient features of management are also emphasized upon.
doi:10.4184/asj.2012.6.2.148
PMCID: PMC3372552  PMID: 22708021
Spinal stenosis; Ligamentum flavum; Alkaptonuria
20.  Motion Induced Artifact Mimicking Cervical Dens Fracture on the CT Scan: A Case Report 
Asian Spine Journal  2012;6(3):216-218.
The diagnostic performance of helical computed tomography (CT) is excellent. However, some artifacts have been reported, such as motion, beam hardening and scatter artifacts. We herein report a case of motion-induced artifact mimicking cervical dens fracture. A 60-year-old man was involved in a motorcycle accident that resulted in cervical spinal cord injury and quadri plegia. Reconstructed CT images of the cervical spine showed a dens fracture. We assessed axial CT in detail, and motion artifact was detected.
doi:10.4184/asj.2012.6.3.216
PMCID: PMC3429615  PMID: 22977704
Reconstruction; Motion artifact; Mimicking; Cervical fracture
21.  Thirty Years after Paul Randall Harrington (September 27, 1911-November 29, 1980) 
Asian Spine Journal  2010;4(2):141-142.
doi:10.4184/asj.2010.4.2.141
PMCID: PMC2996628  PMID: 21165320
22.  Effects of Methylprednisolone on Neuroprotective Effects of Delay Hypothermia on Spinal Cord Injury in Rat 
Asian Spine Journal  2015;9(1):1-6.
Study Design
A retrospective study.
Purpose
The aim of this study was to evaluate the effects of delayed hypothermia on spinal cord injuries in rats. In addition, the effect of methylprednisolone on therapeutic window of hypothermia was evaluated.
Overview of Literature
Several studies have demonstrated that early hypothermia is the most effective neuroprotective modality. However, delayed hypothermia seems to be more practical for patients with traumatic spinal cord injuries. A combination of hypothermia and other neuroprotective methods, such as using methylprednisolone, may help extend the therapeutic window of hypothermia.
Methods
One hundred and twenty male rats were categorized into six groups. The rats in five groups were subjected to spinal cord injury using the weight drop method, followed by treatment, consisting of early hypothermia, late hypothermia, late hypothermia plus methylprednisolone, or methylprednisolone only. Biochemical tests including catalase, malondialdehyde, and superoxide level were evaluated in the injured spinal cord. Behavioral functions of the hind limb were evaluated by Basso-Battle-Bresnaham locomotor rating scale and tail-flick tests.
Results
Functional and biochemical evaluation showed both early and late hypothermia had significant neuroprotective effects. The treated groups did not differ significantly from one another in the behavioral tests. Hypothermia had better biochemical results compared to methylprednisolone. Also, methylprednisolone was shown to extend the therapeutic window of delayed hypothermia.
Conclusions
Hypothermia showed a significant neuroprotective effect, which can be improved with further studies optimizing the duration of hypothermia and the rewarming period. Moreover, the therapeutic effect of the delayed hypothermia can be extended by methylprednisolone.
doi:10.4184/asj.2015.9.1.1
PMCID: PMC4330203
Hypothermia; Spinal cord injury; Methylprednisolone; Hypothermia
23.  Spinal Stenosis Presenting with Scrotal and Perianal Claudication 
Asian Spine Journal  2015;9(1):103-105.
A 63-year-old gentleman presented with a one-year duration of progressive neurogenic claudication. However, unlike most patients who presents with leg symptoms, his pain was felt in his scrotal and perianal region. This was exacerbated with walking and standing, but he had immediate relief with sitting. An magnetic resonance imaging (MRI) was performed which showed severe central canal stenosis. An L3/4 and L4/5 surgical decompression and a transforaminal lumbar interbody fusion was performed, and the patient made good recovery with immediate resolution of symptoms. Although rare, spinal stenosis should be considered a differential when approaching a patient with perianal and scrotal claudication, even in the absence of leg claudication. An MRI is useful to confirm the diagnosis. This rare symptom may be a sign of severe cauda equina compression and we recommend decompression with predictable good results.
doi:10.4184/asj.2015.9.1.103
PMCID: PMC4330204
Spinal; Stenosis; Atypical; Claudication
24.  Cervical Ossification of Posterior Longitudinal Ligament in X-Linked Hypophosphatemic Rickets Revealing Homogeneously Increased Vertebral Bone Density 
Asian Spine Journal  2015;9(1):106-109.
There is no report that describes in detail the radiological and intraoperative findings of rickets with symptomatic cervical ossification of the posterior longitudinal ligament. Here, we describe a case of X-linked hypophosphatemic rickets with cervical ossification of the posterior longitudinal ligament presenting unique radiological and intraoperative findings. The patient presented progressive tetraparesis. Magnetic resonance imaging studies revealed severe cervical spinal cord compression caused by ossification of the posterior longitudinal ligament. Computed tomography scans revealed homogeneously increased vertebral bone density. An expansive laminoplasty was performed. At surgery, homogeneously hard lamina bone was burdened in drilling and opening of the laminae. The patient's neurological symptoms were improved postoperatively. Bony fusion of the hinges occurred postoperatively. Therefore, expansive laminoplasty could be performed for symptomatic cervical ossification of the posterior longitudinal ligament with X-linked hypophosphatemic rickets. However, unusual bone characters should be taken into consideration for careful operation during surgery.
doi:10.4184/asj.2015.9.1.106
PMCID: PMC4330205
Laminoplasty; Rickets; Ossification of posterior longitudinal ligament
25.  Brown Tumor of the Cervical Spines: A Case Report with Literature Review 
Asian Spine Journal  2015;9(1):110-120.
To report a rare case of axis brown tumor and to review literature of cervical spine brown tumor. Brown tumor is a rare bone lesion, incidence less than 5% in primary hyperparathyroidism. It is more common in secondary hyperparathyroidism with up to 13% of cases. Brown tumor reactive lesion forms as a result of disturbed bone remodeling due to long standing increase in parathyroid hormones. Cervical spine involvement is extremely rare, can be confused with serous spine lesions. To date, only four cases of cervical spine involvement have been reported. Three were due to secondary hyperparathyroidism. Only one was reported to involve the axis and was due to secondary hyperparathyroidism. This is the first reported case of axis brown tumor due to primary hyperparathyroidism. A case report of brown tumor is presented. A literature review was conducted by a Medline search of reported cases of brown tumor, key words: brown tumor, osteoclastoma and cervical lesions. The resulting papers were reviewed and cervical spine cases were listed then classified according to the level, cause, and management. Only four previous cases involved the cervical spine. Three were caused by secondary hyperparathyroidism and one was by primary hyperparathyroidism which involved the C6. Our case was the first case of C2 involvement of primary hyperparathyroidism and it was managed conservatively. Brown tumor, a rare spinal tumor that presents with high PTH and giant cells, requires a high level of suspicion.
doi:10.4184/asj.2015.9.1.110
PMCID: PMC4330206
Osteitis fibrosa cystica; Axis neoplasm; Osteoclastoma; Brown tumor; Hyperparathyroidism

Results 1-25 (391)