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1.  Raising the Breast Health Awareness amongst Women in an Urban Slum Area in Alexandria, Egypt 
Breast Care  2011;6(5):375-379.
Breast Cancer (BC) is the most frequently occurring cancer among Egyptian women. This study aimed to determine the effectiveness of a health education program on raising the knowledge related to BC, its risk factors, and some related preventive practices among women living in an urban slum area in Alexandria.
Patients and Methods
A pre-/post-test interventional study was conducted during 2009–2010 on a random sample of women aged 30–65 years (n = 486) living in a slum area in Alexandria, Egypt. 20 health education sessions were carried out to educate the women on BC risk factors and some preventive practices. Previously trained nurses educated the sampled women on breast self-examination (BSE). The women's knowledge and opinion about BC and their practice of BSE were evaluated before and 3 months after the intervention.
The findings indicated a significant increase in the mean knowledge score regarding BC and the mean opinion score regarding some BC risk factors. A significant increase in the practice of BSE was observed post intervention.
This study confirms the effectiveness of intervention programs in improving the knowledge about BC risk factors and practice of BSE even in a group of women with a low literacy rate living in a slum area.
PMCID: PMC3357171  PMID: 22619648
Breast cancer; Breast self-examination; Breast awareness; Knowledge; Egypt
2.  Assisted Hatching—A Meta-Analysis of Randomized Controlled Trials 
Purpose: To conduct a meta-analysis of randomized controlled trials (RCTs) on assisted hatching.
Methods: One hundred sixty-five studies were retrieved from the literature, but only 13 of them fitted our selection criteria. The meta-analysis was conducted using the RevMan software with the Peto-modified Mantel–Haenszel method.
Results: Assisted hatching increases the pregnancy [OR (±95% CI) = 2.51 (1.91–3.29)], implantation [OR (±95% CI) = 2.38 (1.87–3.03)], and ongoing pregnancy rates [OR (±95% CI) = 2.65 (1.85–3.79)] significantly in poor prognosis patients undergoing IVF or ICSI. For patients with repeated IVF failures, the OR (±95% CI) were 2.84 (1.99–4.06) for pregnancy, 2.53 (1.85–3.47) for implantation, and 3.51 (2.12–5.82) for ongoing pregnancy rates, in favor of assisted hatching.
Conclusions: Assisted hatching increases the pregnancy, implantation, and ongoing pregnancy rates significantly in patients with a poor prognosis undergoing IVF or ICSI, particularly those with repeated failures.
PMCID: PMC3455281  PMID: 12948097
Assisted hatching; intracytoplasmic sperm injection; in vitro fertilization; meta-analysis; randomized trials
3.  Impact of Technical Difficulties, Choice of Catheter, and the Presence of Blood on the Success of Embryo Transfer—Experience from a Single Provider 
Purpose: To investigate the impact of technical difficulties, choice of catheter, and the presence of blood during embryo transfer on the results of in vitro fertilization and ICSI.
Methods: A cohort of 784 consecutive cycles in 655 in vitro fertilization and ICSI patients were studied.
Results: Negotiating the cervix, using the volsellum, presence of blood on the catheter wall or on the cervix did not affect the results. Changing the catheter and blood on the catheter tip reduced the pregnancy (P < 0.05 and P < 0.05) and implantation rates (P < 0.001 and P < 0.01). The Ultrasoft catheter produced higher pregnancy (P < 0.0005) and implantation rates (P < 0.01) compared to the more rigid Frydman catheter.
Conclusions: Negotiation of the cervix, the use of a volsellum, and the presence of blood on the catheter wall or on the cervix do not affect the results. Changing the catheter and blood on the catheter tip significantly diminish the pregnancy and implantation rates. Soft catheters perform better.
PMCID: PMC3455637  PMID: 12762411
Clinical pregnancy rate; embryo transfer; implantation; implantation rate; in vitro fertilization

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