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BMJ : British Medical Journal (1)
Clinical ophthalmology (Auckland, N.Z.) (1)
The British Journal of Ophthalmology (1)
The British journal of ophthalmology (1)
Hossain, Parwez (4)
Amoaku, Winfried M (1)
Anderson, David F (1)
Browning, Andrew C (1)
Coggon, David (1)
Konstantopoulos, Aristides (1)
Malik, Rayaz A (1)
Sachdev, Arun (1)
Seetho, Ian W (1)
Shah, Ameet (1)
Tavakoli, Mitra (1)
Year of Publication
Geographic Variations in Microbial Keratitis: An analysis of the Peer-Reviewed Literature
The British journal of ophthalmology
The epidemiology of microbial keratitis has been investigated in several studies by analysis of organisms cultured from corneal scrapes. However, a comparison of the frequency of different organisms causing keratitis in different parts of the world is lacking. We present a review incorporating an analysis of data from studies worldwide. The data provide a comparison of the frequency of culture-positive organisms found in different parts of the world.
The highest proportion of bacterial corneal ulcers was reported in studies from North America, Australia, the Netherlands and Singapore. The highest proportion of staphylococcal ulcers was found in a study from Paraguay whilst the highest proportion of pseudomonas ulcers was reported in a study from Bangkok. The highest proportions of fungal infections were found in studies from India and Nepal. Possible explanations for these observed geographic variations are discussed.
cornea; keratitis; eye; infection; epidemiology
Recent advances in ophthalmic anterior segment imaging: a new era for ophthalmic diagnosis?
Anderson, David F
The British Journal of Ophthalmology
Anterior segment imaging is a rapidly advancing field of ophthalmology. New imaging modalities, such as rotating Scheimpflug imaging (Pentacam‐Scheimpflug) and anterior segment optical coherence tomography (Visante OCT and Slit‐Lamp OCT), have recently become commercially available. These new modalities supplement the more established imaging devices of Orbscan scanning slit topography and ultrasound biomicroscopy (UBM). All devices promise quantitative information and qualitative imaging of the cornea and anterior chamber. They provide a quantitative angle estimation by calculating the angle between the iris surface and the posterior corneal surface. Direct angle visualisation is possible with the OCT devices and UBM; they provide images of the scleral spur, ciliary body, ciliary sulcus and even canal of Schlemm in some eyes. Pentacam‐Scheimpflug can measure net corneal power, a feature particularly useful for cataract patients having undergone previous corneal surgery. Anterior segment OCT can measure corneal flap depth following LASIK and anterior chamber width prior to phakic intraocular lens implantation. The arrival of the new imaging devices may herald the dawn of a new era for ophthalmic diagnosis, particularly in view of the ease and non‐contact nature of examination.
Artificial means for restoring vision
Seetho, Ian W
Browning, Andrew C
Amoaku, Winfried M
BMJ : British Medical Journal
Clinical applications of corneal confocal microscopy
Malik, Rayaz A
Clinical ophthalmology (Auckland, N.Z.)
Corneal confocal microscopy is a novel clinical technique for the study of corneal cellular structure. It provides images which are comparable to in-vitro histochemical techniques delineating corneal epithelium, Bowman’s layer, stroma, Descemet’s membrane and the corneal endothelium. Because, corneal confocal microscopy is a non invasive technique for in vivo imaging of the living cornea it has huge clinical potential to investigate numerous corneal diseases. Thus far it has been used in the detection and management of pathologic and infectious conditions, corneal dystrophies and ecstasies, monitoring contact lens induced corneal changes and for pre and post surgical evaluation (PRK, LASIK and LASEK, flap evaluations and Radial Keratotomy), and penetrating keratoplasty. Most recently it has been used as a surrogate for peripheral nerve damage in a variety of peripheral neuropathies and may have potential in acting as a surrogate marker for endothelial abnormalities.
corneal confocal microscopy; cornea; infective keratitis; corneal dystrophy; neuropathy
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