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1.  Measurement of striated muscle fibre diameters using interactive computer-aided microscopy 
Journal of Clinical Pathology  1982;35(11):1268-1271.
We have measured muscle fibre diameters using two methods of interactive computer-aided microscopy. They are simple to perform, reproducible and more convenient than manual methods of measurement. The technique is of general application to histological measurement.
PMCID: PMC497940  PMID: 7142435
2.  Measurement in jejunal biopsies by computer-aided microscopy. 
Journal of Clinical Pathology  1980;33(3):254-261.
A method of morphometric analysis of jejunal mucosa using computer-aided microscopy is described. It is based on the technique of interactive computer graphics with definition by the observer of areas and lengths for measurement, but it also includes automatic measurements based on grey-level segmentation. The analyses are performed rapidly and efficiently. The technique is applicable to the analysis of biopsy tissue from many sites.
PMCID: PMC1146049  PMID: 7381024
3.  Reading chest radiographs for pneumoconiosis by computer. 
Computer programs for measuring simple pneumoconiosis in radiographs are described and assessed. The 36 films studied had been read by 11 skilled human observers and a 'radiological score' of pneumoconiotic severity was therefore available for each film. The computer assigns to each square grid of side 3-6 mm a measure which reflects the unevenness of the density distribution in that grid. The 'computed score' is defined as the mean diversity over all relevant grids in both lung fields. On the set of 36 films the correlation between radiological score and computed score was 0-88. By contrast, the correlation between the score assigned by a single observer and the average of the scores assigned by the other 10 was in the range 0-95 to 0-98. The program can use the computed score to classify a film into one of the four major International Labour Office (ILO) U/C categories, the success rate of this process being 80% compared with those quoted by other workers in the range 45%-65%. If the films used in this study be typical, then the program described may form the basis of an automatic method for measuring pneumoconiosis in epidemiological work.
PMCID: PMC1008075  PMID: 1103955

Results 1-3 (3)