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2.  Radiation leukaemogenesis: is virus really necessary? 
British Journal of Cancer  1978;38(1):24-33.
Generalized lymphosarcomatosis (leukaemia) of non-thymic type occurs in mice bearing 90Sr or 239Pu or 226Ra. Tumours passaged from such mice have been tested for tumour-associated transplantation antigens that could provoke a protective immunity which would be expected if such antigens were determined by virus activated by the irradiation. Sub-threshold doses of living syngeneic tumour, large doses of living allogeneic tumour and large doses of killed syngeneic tumour were without protective effect. This suggests that viruses observed electron micrographically in such tumours are passengers and not causative.
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PMCID: PMC2009681  PMID: 581177
3.  Histochemical Phosphatases and Metachromasia in Murine Tumours Induced by Bone Seeking Radionuclides 
British Journal of Cancer  1974;29(3):206-222.
Tumours induced in mice, either CBA normal and chimaerical, or C3H, by 90Sr or 226Ra or plutonium have been examined histochemically with (1) diazotate fast red violet LB salt in naphthol AS-MX phosphate buffer at pH 8·6 and 5·2, (2) 1: 9 dimethyl methylene blue (Taylor).
It is concluded:
(a) The diagnosis of osteosarcoma is facilitated with Taylor's Blue which stains osteoid metachromatically. Cells of osteosarcoma, like normal osteoblasts, contain alkaline phosphatase but this may be lost by mutation either in the original tumour or subsequently on passage of the tumour serially to compatible hosts.
(b) Osteosarcomata may contain giant-cells of two forms, bizarre tumour cells and osteoclasts; the latter contain acid phosphatase. Osteosarcomata which retain their osteoid on serial passage have few cells containing acid phosphatases.
(c) Primitive mesenchymal cell tumours of angiomatous form may occur, if the bone marrow is irradiated, e.g. by 90Sr-90Y and Pu. These tumours lack osteoid and cells interpretable as osteoblasts or osteoclasts (though they destroy bone).
(d) Tumours classifiable as fibrosarcomata occur rarely, and may be truly of fibroblastic origin or be mutated osteosarcomata.
(e) Lymphomata also occur when the marrow is irradiated (90Sr-90Y and Pu). They may be generalized, when their cells may contain alkaline phosphatase or lack it. They may be localized to abdominal viscera, the reticulo-sarcomatous form, in which case the cells lack alkaline phosphatase.
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PMCID: PMC2009098  PMID: 4133784
4.  Malignancy from Radium 
British Journal of Cancer  1970;24(2):195-207.
Human experience of the toxicity of radium acts as a guide for the setting of occupationally permissible levels for radioactive nucleides, especially bone-seekers. Reviewing the published statements and photomicrographs in early reports especially those of Martland (1931) one can make a case that malignancy was induced in bone-marrow (leukaemia, malignant myelosclerosis) as well as in bone (osteosarcoma) by radium, especially with large doses. Three case reports of radium intoxication in Britons are noted as compatible with this suggestion, after revised interpretation in two of them.
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PMCID: PMC2008571  PMID: 5271269
7.  Biological hazards of nuclear fission * 
The Eugenics Review  1956;48(3):141-148.
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PMCID: PMC2973689  PMID: 21260715
9.  Prevention of Homologous Serum Jaundice* 
British Medical Journal  1945;2(4430):759-760.
PMCID: PMC2060349  PMID: 20786423
11.  Homologous Serum Jaundice* 
British Medical Journal  1944;2(4364):268-269.
PMCID: PMC2286101  PMID: 20785609
15.  Nuclear Medicine 
British Medical Journal  1968;4(5625):243.
PMCID: PMC1912215
16.  Unusual Twins 
British Medical Journal  1966;2(5520):1008.
PMCID: PMC1944435
17.  Radioactive Fallout 
British Medical Journal  1966;2(5507):223.
PMCID: PMC1943177
18.  Book Reviews 
PMCID: PMC1008309
19.  Atomic Energy 
British Medical Journal  1964;1(5389):1037.
PMCID: PMC1814214
21.  Man in Nuclear War 
British Medical Journal  1964;1(5377):233-234.
PMCID: PMC1813064
23.  Radiation Protection 
British Medical Journal  1963;1(5338):1153.
PMCID: PMC2123033
25.  Hazards of Radiation 
British Medical Journal  1962;2(5308):853-854.
PMCID: PMC1926270

Results 1-25 (33)