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1.  An improved competitive inhibition enzymatic immunoassay method for tetrodotoxin quantification 
Quantifying tetrodotoxin (TTX) has been a challenge in both ecological and medical research due to the cost, time and training required of most quantification techniques. Here we present a modified Competitive Inhibition Enzymatic Immunoassay for the quantification of TTX, and to aid researchers in the optimization of this technique for widespread use with a high degree of accuracy and repeatability.
doi:10.1186/1480-9222-14-3
PMCID: PMC3337821  PMID: 22410273
Tetrodotoxin; CIEIA; HPLC
2.  Behavioral and Chemical Ecology of Marine Organisms with Respect to Tetrodotoxin 
Marine Drugs  2010;8(3):381-398.
The behavioral and chemical ecology of marine organisms that possess tetrodotoxin (TTX) has not been comprehensively reviewed in one work to date. The evidence for TTX as an antipredator defense, as venom, as a sex pheromone, and as an attractant for TTX-sequestering organisms is discussed. Little is known about the adaptive value of TTX in microbial producers; thus, I focus on what is known about metazoans that are purported to accumulate TTX through diet or symbioses. Much of what has been proposed is inferred based on the anatomical distribution of TTX. Direct empirical tests of these hypotheses are absent in most cases.
doi:10.3390/md8030381
PMCID: PMC2857358  PMID: 20411104
tetrodotoxin; ecology; defense; venom; pheromone

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