PMCC PMCC

Search tips
Search criteria

Advanced
Results 1-13 (13)
 

Clipboard (0)
None

Select a Filter Below

Journals
Authors
Year of Publication
more »
1.  Life in Science: William C Summers 
Bacteriophage  2014;4(1):e26691.
doi:10.4161/bact.26691
PMCID: PMC3895083  PMID: 24478937
2.  The strange history of phage therapy 
Bacteriophage  2012;2(2):130-133.
Since the enlightenment, scientists have enjoyed a self-image as rational actors, guided only by reason, evidence and logic. When the Royal Society of London was founded in 1660 it chose as its motto “nullius in verba” (often translated as “on the word of no one”) a reference to Horace’s Epistles “Nullius addictus iurare in verba magistri…” (being not obliged swear allegiance to any master). Similar to our 21st century contemporaries who embrace the “new evidenced-based medicine,” the “virtuosi” of the Royal Society proclaimed a new era in science based only on observation and direct experience.
doi:10.4161/bact.20757
PMCID: PMC3442826  PMID: 23050223
phage therapy; Félix d'Herelle; Gunther Stent; Frederick Twort; lytic principle
3.  In the beginning… 
Bacteriophage  2011;1(1):50-51.
doi:10.4161/bact.1.1.14070
PMCID: PMC3109447  PMID: 21687535
bacteriophage; Félix d'Herelle; immunity; Pasteur; plaque; lysis; discovery
8.  Herpes Simplex Virus Type 1 Infection of Isogenic Epstein-Barr Virus Genome-Negative and -Positive Burkitt's Lymphoma-Derived Cell Lines 
Journal of Virology  1979;30(1):248-254.
The Epstein-Barr virus (EBV) genome-negative Burkitt's lymphoma-derived cell lines BJAB and Ramos and their in vitro EBV-converted sublines BJAB-B1, BJAB-A5, BJAB-B95-8, and AW-Ramos were infected with high multiplicities of herpes simplex virus type 1 (HSV-1; 10 to 70 PFU/cell). Cultures were monitored for cell growth and HSV-1 DNA synthesis. EBV-converted BJAB cultures were more permissive for HSV-1 infection than BJAB cultures. Significant cell killing and HSV-1 DNA synthesis were observed during the first 48 h of infection in the EBV-converted BJAB cultures but not in the BJAB cultures. The EBV-converted BJAB-B1 cell line contains an appreciable fraction of EBV-negative cells. Therefore, it was cloned. EBV-positive and -negative cells were identified by using EBV-determined nuclear antigen anti-complement immunofluorescence. Two types of subclones were identified: (i) those which contained both EBV-determined nuclear antigen-positive and -negative cells and (ii) those which contained only EBV-determined nuclear antigen-negative cells. When levels of HSV-1 DNA synthesis were measured in these subclones, it was found that the former were more permissive for HSV-1 infection than the latter. Thus, the presence of the EBV genome in BJAB cells correlates with increased permissiveness of these cells for HSV-1 during the first 48 h of infection. Nonetheless, persistent HSV-1 infections were established in both BJAB and EBV-converted BJAB-B1 cultures. No differences in extent of permissiveness for HSV-1 infection were found for Ramos and EBV-converted AW-Ramos cells.
PMCID: PMC353319  PMID: 225521
9.  Pasteurella pestis Bacteriophage H and Escherichia coli Bacteriophage φII Are Nearly Identical 
Journal of Virology  1973;11(2):306-313.
Electron microscopy examination of φII-H deoxyribonucleic acid heteroduplexes, together with polyacrylamide gel electrophoretic analyses of phage ribonucleic acid species and proteins labeled in φII or H-infected cells, demonstrates that Pasteurella pestis phage H is nearly identical to coliphage φII.
Images
PMCID: PMC355096  PMID: 4569706

Results 1-13 (13)