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1.  Experiences of social oppression among men who have sex with men in a cosmopolitan city in Nigeria 
In several African countries, men who have sex with men (MSM) are becoming visible, as a result of which they are now victims of human rights violations. This has a negative effect on their ability to access services targeted at human immunodeficiency virus (HIV) prevention and care. The main objective of this study was to document the experiences of social oppression among MSM in Lagos State, Nigeria.
Simple random sampling was used to select three of the seven local government areas in Lagos State that had community centers. Snowball sampling was used to recruit 291 participants. The survey instrument was a pretested questionnaire. The results were presented as means and percentages. Univariate, bivariate, and multivariate analysis was carried out at P<0.05.
The mean age of the participants was 25.3±4.6 years, and the majority (66.0%) were currently single and not in a steady relationship. Half of the men self-identified as gay and about 48% as bisexual. Alcohol use occurred in 56.7% of the respondents, about a quarter (25.8%) smoked cigarettes, and 11.0% reported using hard drugs. The commonest acts of human rights violation and or violence reported were aggression 35.7%, alienation 29.9%, verbal abuse 19.2%, physical abuse 17.9%, rape by a man 16.8%, and psychological abuse 20.3%. The predictors of human rights violation were level of education (adjusted odds ratio 2.6, P=0.019), marital status (adjusted odds ratio 2.3, P=0.005), and sexual orientation (adjusted odds ratio 1.9, P=0.017). For physical and sexual abuse, MSM who consumed alcohol and were homosexual/transgender were at risk.
This study showed that a high proportion of MSM had experienced various forms of human rights violation and abuse as a result of their sexual orientation/identity. There is a need to document and quantify these happenings, which can serve as an advocacy tool for reform.
PMCID: PMC4278793  PMID: 25565899
social oppression; men who have sex with men; Lagos; Nigeria
2.  Incidence of and socio-biologic risk factors for spontaneous preterm birth in HIV positive Nigerian women 
Recent studies have identified HIV as a leading contributor to preterm delivery and its associated morbidity and mortality. However little or no information exists in our sub-region on this subject. Identifying the factors associated with preterm delivery in HIV positive women in our country and sub-region will not only prevent mother to child transmission of HIV virus but will also reduce the morbidity and mortality associated with prematurity and low birth weight. This study was designed to determine the incidence and risk factors for preterm delivery in HIV positive Nigerians.
The required data for this retrospective study was extracted from the data base of a cohort study of the outcome of prevention of mother to child transmission at the Nigerian Institute of Medical Research, Lagos. Only data of women that met the eligibility of spontaneous delivery after 20 weeks of gestation were included. Ethical approval was obtained from the Institution’s Ethical Review Board.
181 women out of the 1626 eligible for inclusion into the study had spontaneous preterm delivery (11.1%). The mean birth weight was 3.1 ± 0.4 kg, with 10.3% having LBW. Spontaneous preterm delivery was found to be significantly associated with unmarried status (cOR: 1.7;1.52-2.57), baseline CD4 count <200 cells/mm3(cOR: 1.8; 1.16-2.99), presence of opportunistic infection at delivery (cOR: 2.2;1.23-3.57), multiple pregnancy (cOR 10.4; 4.24 – 26.17), use of PI based triple ARV therapy (eOR 10.2; 5.52 – 18.8) in the first trimester (cOR 2.5; 1.77 – 3.52) on univariate analysis. However after multivariate analysis controlling for potential confounding variables including low birth weight, only multiple pregnancy (aOR: 8.6; CI: 6.73 – 12.9), presence of opportunistic infection at delivery (aOR: 1.9; CI: 1.1 – 5.7), and 1st trimester exposure to PI based triple therapy (aOR: 5.4; CI: 3.4 – 7.8) retained their significant association with preterm delivery.
The spontaneous preterm delivery rate among our cohort was 11.1%. HIV positive women with multiple pregnancies, symptomatic HIV infection at delivery and first trimester fetal exposure to PI based triple therapy were found to be at risk of spontaneous preterm delivery. Early booking and non-use of PI based triple therapy in the first trimester will significantly reduce the risk of preterm delivery.
PMCID: PMC3449176  PMID: 22958756
Spontaneous preterm birth/delivery HIV; Pregnancy; Viral load; CD4 count; Low birth weight

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