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1.  Effect of Kuberaksha Patra Churna, Vriddhadaru Mula Churna and Kandughna Taila in Shlipada (Manifested filariasis) 
Ayu  2012;33(1):102-109.
At present there are effective drugs in eradicating microfilariae but treatments to control the progression of manifested filariasis, periodic adenolymphangitis (ADL) and lymphedema are not available in conventional system of medicine. So far National Ayurveda Research Institute for Vector-borne diseases, Vijayawada, has conducted many clinical trails on manifested filariasis patients with the classical Ayurvedic herbal, herbo-mineral drugs and found significant results on ADL, lymphedema and other acute and chronic clinical manifestations. An effort has been made to find the effect of Kuberaksha Patra Churna [Caesalpinia bonduc (L.) Roxb.], Vriddhadaru Mula Churna [Argyreia nervosa (Burm.f.) Boj.] and Kandughna Taila (oil prepared from 10 Ayurvedic drugs) in manifested filarial patients. Based on inclusion criteria 133 patients were included in three groups (45 in Gr.I, 45 in Gr.II and 43 in Gr.III) and 120 patients completed the study (40 in each group). In Gr. I Argyreia nervosa (Burm.f.) Boj. root powder, Caesalpinia bonduc (L.) Roxb. leaf powder mixed equally was given in the dose of 5 g twice a day for 30 days. In Gr.II along with Gr. I internal drugs Kandughna Taila was applied externally in sufficient quantity once a day for 30 days. Gr. III is a control study with Ayurvedic established drug ‘Nityananda Rasa’ 1 tablet thrice daily for 30 days. Group I and II drugs showed highly significant effect on lymphedema, lymphadenitis, lymphangitis, pain, tenderness, heaviness, deformity, fever and rigors (P<0.0001). Group III drug showed highly significant (P<0.0001) effect on lymphedema, deformity and heaviness; statistically significant (P=0.0018) on pain and tenderness; Significant effect on fever (P=0.0290), rigor (P=0.0290) and in lymphangitis (P=0.0384) and non-significant effect on lymphadenitis (P=0.1033). On statistical analysis effect of treatment on Hb and eosinophil count was found non-significant in three groups. On ESR, effect of treatment was found significant in Gr. III and non-significant in Gr. I and Gr. II.
doi:10.4103/0974-8520.100324
PMCID: PMC3456846  PMID: 23049193
Argyreia nervosa; Caesalpinia bonduc; fever; filariasis; lymphadenitis; lymphangitis; lymphedema; Shlipada
2.  Analytical study of Kuberaksha/Kantaki Karanja Patra Churna [Caesalpinia Bonduc (L.) Roxb. leaf powder] 
Ayu  2010;31(2):251-254.
Caesalpinia bonduc (L.) Roxb. (Kuberaksha) is an Ayurvedic herb used in the management of malaria, liver disorders, worms, edematous conditions, etc. Based on classical Ayurvedic textual indications and recent pharmacological studies, its leaf powder was selected for studying its effect clinically on filaria. Before conducting the clinical trails, this leaf powder was subjected to certain chemical studies to find the pH, ash value, extractive values, High Performance Thin Layer Chromatography (HPTLC), etc. for standardization of the drug.
doi:10.4103/0974-8520.72410
PMCID: PMC3215374  PMID: 22131720
Acid insoluble ash; analytical study; Caesalpinia bonduc; Kuberaksa leaf powder; loss on drying; pH value; total ash
3.  Historical perspective on the usage of perfumes and scented Articles in ancient Indian literatures 
Ancient Science of Life  2008;28(2):33-39.
In India perfumes and scented articles were in use from pre Vedic and Vedic periods for religious practices, social customs, and domestic rituals and later gradually became part and parcel of human life. Perfumes were also used in cosmetics and beauty aids. Medicinal values of many perfumes were well known to ancient Indians and were used in both rituals and to treat diseases. Medicated fumigation (dhupan) was an advanced method for medicinal purposes. Medicated oils, collyriums, powders were prepared from perfumes used externally in many diseases. Perfumes were also anointed in various body parts (Anulepan). Chewing betel leaves along with fragrant material like nutmeg, mace, etc. (Tambulam) was used with a view to rendering mouth clean and fragrant. usage of scented oils to massage body(Abhyanga) which keeps the skin smooth, healthy and invigorating; Udvartanam, massaging various body parts; Udgarshanam, scrubbing; Utsadanam rubbing with scented powders etc., were some of the health protective and disease eliminating procedures. Scented drugs and perfumes enhance the quality, activity and pleasantness of these processes.
PMCID: PMC3336354  PMID: 22557310
4.  Netra darpanamu - A Unique book on eye diseases 
Ancient Science of Life  2007;27(2):44-49.
Netra Darpanamu is the only book written exclusively on Eye diseases in Telugu. This Ayurvedic book, which is famous in Andhra Pradesh, was first published in 1908 in Eluru. The book is written in chaste Telugu poetry, comprising the types of treatment followed by 36 recipes. This book contains names of various eye diseases, treatment procedures like bandages, plasters, collyriums and regimen of food and behaviour. This article aims to highlight the importance of this book in treating various eye diseases.
PMCID: PMC3330849  PMID: 22557269
5.  CONTRIBUTION OF KAUTILYA ARTHASASHTRA TOWARDS DRAVYAGUNA, RASASASTRA AND BHAISHAJYAKALPANA BRANCHES OF AYURVEDIC MEDICINE 
Ancient Science of Life  2006;26(1-2):26-38.
It is believed Kautilya, whose name was Vishnugupta and is popular as Chanakya (The son of Chanaka) wrote Arthasastra. This article is mainly based on Kautilya's Arthasastra, translated by R. Shamasastry. In the preface of 1st to 5th edition of this text, the translator Dr. R. Shamasastry tried to clarify the uncertainty regarding the name of the author and the time of the text. Kamandaka and Dandi quotation support the time of this treatise somewhere between 321 and 300 B.C. These quotations also support the authorship of Vishnugupta. According to Kadambari, the author of Arthasastra was Kautilya and according to Manu and Dharmasastras, Chanakya had written this Arthasastra. Though there are some controversies regarding the name of the author and time of this text, translator R. Shamasastry tried his level best in providing proper support for naming this text as Kautilya's Arthasastra as the original available manuscript contains the name of Kautilya at the end of each of the hundred and fifty chapters of the work. Still there is controversy regarding the exact time of this text. If views of many scholars is considered, time of the text can be placed between 3rd century B.C. to 3rd century A.D. This translated original text contains 15 books (Basic discussions of the text), 150 chapters, 180 sections and 6000 Slokas (Thirty two syllables are considered as one Sloka).
PMCID: PMC3335230  PMID: 22557221
6.  A CONTEMPORARY SCIENTIFIC SUPPORT ON ROLE OF ANCIENT AYURVEDIC DIET AND CONCEPTS IN DIABETES MELLITUS (MADHUMEHA) 
Ancient Science of Life  2006;25(3-4):84-91.
Diabetes Mellitus (Madhumeha) is a well-known clinical syndrome since antiquity. First time the role of Diet in the prevention, etiology and treatment of Diabetes was mentioned in Ayurveda under the heading of Prameha and Madumeha. Caraka Samhita, Susruta Samhita and other Ayurvedic classics have appropriate descriptions on the role of diet, habits and life style in Prameha and Madhumeha, which is akin to Diabetes. Recent modern (contemporary) Researches and statistics support these descriptions. Aim of this article is to alarm people regarding role of diet and lifestyle in Diabetes through Ayurvedic approach and contemporary scientific correlation with support of clinical and statistical data.
PMCID: PMC3335207  PMID: 22557212
7.  SOME IMPORTANT ASPECTS OF NADIPARIKSHA FROM BASAVARAJIYAM 
Ancient Science of Life  2004;24(1):27-29.
Nadi Pariksha has been said as one of the important Ashta sthana parikshas. Though, there are some physicians who are doing miracles just by examining Nadi, this system of examination in many views has became extinct now a days. The main reason for this is, now a days very little research and practice is going on regarding this technique. So, many resent samhitas and Chikitsa granthas like Sarangadhara, Yogaratnakara, etc., have highlighted Nadi pariksha. Basavarajiyam is also one of those resent treatises (19th century), which has highlighted this ancient type of examination of the patient. Basavarajiyam is a popular Ayurvedic heritage of Andhra Pradesh written by Basavaraju, son of Namahshivaya and disciple of Ramadeshika. The author has referred many books and collected many slokas from various ancient granthas and quoted them in 25 Prakaranas along with his own views and quotations. This book was translated in Telugu language by Puvvada surya Narayana Rao and lppublished by A.B.S.publications, Rajahmundry A.P. In this paper Nadi sthanas (Location), Nadi types, Nadi Pareeksha vidhi (examination of Nadi) and its utilities in different aspects of the disease are dealt, which have been mentioned in Basavarajeeyam.
PMCID: PMC3330914  PMID: 22557147

Results 1-8 (8)