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author:("cathy, B")
3.  Antimicrobial resistance to benzylpenicillin in invasive pneumococcal disease in Belgium, 2003–2010: the effect of altering clinical breakpoints 
Epidemiology and Infection  2012;141(3):490-495.
The Belgian data (2003–2010) for the European Antimicrobial Resistance Surveillance Network (EARS-Net) showed a significant decreasing trend in the proportion of penicillin non-susceptible Streptococcus pneumoniae (9·4% to <1%) from blood and CSF isolates. We found that 75% of this decrease was explained by a change in Clinical and Laboratory Standards Institute (CLSI) breakpoints as the trend disappeared if only the new breakpoints were applied. Applying only European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints also resulted in a relatively stable proportion of penicillin non-susceptibility (average 5%), but this proportion was 7–13 times higher than with the new CLSI breakpoints. When the new CLSI breakpoints alone are used, fewer than 1% of bacteraemia isolates were penicillin non-susceptible during the entire period, but the proportion of non-susceptible meningitis isolates rose from 6·3% in 2003 to 15·9% between 2003 and 2010. Changing breakpoints should lead to retrospective analysis of historical data to minimize wrongly interpreting resistance trends.
PMCID: PMC3566593  PMID: 22677465
Antibiotic resistance; clinical microbiology; Streptococcus pneumoniae (pneumococcus); surveillance system
4.  Achievements of BSI hospital-wide surveillance in Belgium 
BMC Proceedings  2011;5(Suppl 6):P234.
PMCID: PMC3239660
5.  The fate of orally available antimicrobials 
BMC Proceedings  2011;5(Suppl 6):P44.
PMCID: PMC3239777
6.  Timeliness of syndromic influenza surveillance through work and school absenteeism 
Archives of Public Health  2010;68(3):115-120.
In this paper, we investigate the usefulness of work and school absenteeism surveillance as an early warning system for influenza. In particular, time trends in daily absenteeism rates collected during the A(H1N1)2009 pandemic are compared with weekly incidence rates of influenza-like illness (ILI) obtained from the Belgian Sentinel General Practitioner (SGP) network. The results indicate a rise in absenteeism rates prior to the onset of the influenza epidemic, suggesting that absenteeism surveillance is a promising tool for early warning of influenza epidemics. To convincingly conclude on the usefulness of absenteeism data for early warning, additional data covering several influenza seasons is needed.
PMCID: PMC3463027
School absenteeism; worker absenteeism; influenza; influenza A virus; H1N1 subtype
7.  Surveillance of influenza-like illness in Belgian nursing homes 
Archives of Public Health  2010;68(3):100-108.
PMCID: PMC3463032
Nursing homes; surveillance; influenza; A(H1N1)2009; influenza-like illness; seasonal flu

Results 1-8 (8)