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1.  The split hand sign 
Amyotrophic Lateral sclerosis (ALS) is a disease characterized by pure motor asymmetric wasting of various muscles with associated upper motor neuron signs. The split hand sign, which is because of dissociated muscle weakness in the hands (thenar muscles disproportionately wasted as compared to the hypothenar muscles) is a useful clinical sign for bed side diagnosis of ALS.
PMCID: PMC3424792  PMID: 22919187
Amyotrophic lateral sclerosis; dissociated intrinsic hand muscle weakness; split hand sign
2.  Innovative approach for prevention and treatment of post subarachnoid hemorrhage vasospasm: A preliminary report 
Asian Journal of Neurosurgery  2012;7(2):78-80.
More than one third of patients with subarachnoid hemorrhage (SAH) develop clinically significant vasospasm, as a leading morbidity and mortality factor for these patients. It is widely accepted that a) Degradation products of blood are the causative factors of vasospasm b) The amount of subarachnoid blood seen on admission CT is correlated to the risk of vasospasm c) Reducing the subarachnoid clot burden at the time of surgery reduces the risk of vasospasm. But there is no existing method to clear the blood from subarachnoid spaces satisfactorily. We have evaluated safety and feasibility of fluid exchange catheter system in SAH, to achieve this goal. We were successful in clearing cisternal blood in three patients with aneurysmal rupture with fluid exchange catheter system. Baseline CT scan of brain was performed immediately after the surgery and then at the end of irrigation. The amount of subarachnoid blood was evaluated. This innovative, fluid exchange catheter system infuses and aspirates micro volumes of drug solution in a cyclic mode, ensuring isobaric exchange of fluids. The result is good clearance of blood in subarachnoid spaces were seen in all the patients. Also, significant improvement in neurological deficits secondary to vasospasm was seen. We conclude that the fluid exchange catheter system is safe and adoptable in neurosurgical practice.
PMCID: PMC3410165  PMID: 22870156
Cisternal blood; flux irrigation system; subarachnoid hemorrhage; vasospasm
3.  Idiopathic Calcinosis Cutis of Nasal Dorsum 
A 23-year-old lady presented with a slowly progressing firm mass on the nasal dorsum since 8 months. Her biochemical, haematological and collagen vascular disease screening tests were normal. Radiographs of the nasal bones showed a subcutaneous calcifying lesion with no evidence of nasal bone erosion. A diagnosis of idiopathic calcinosis cutis (ICC) was made. The mass was excised and soft tissue defect was augmented with silicone prosthesis. The histopathology with the haematoxylin and eosin staining and von Kossa stain confirmed the diagnosis of calcinosis cutis. This is an unusual presentation of ICC involving the nasal dorsum requiring surgery and nasal dorsal augmentation with silicone prosthesis.
PMCID: PMC3339131  PMID: 22557858
Calcinosis cutis; idiopathic; nasal dorsum
4.  Minerva 
BMJ : British Medical Journal  2007;334(7584):102.
PMCID: PMC1767289
5.  Hormone replacement therapy  
BMJ : British Medical Journal  2002;325(7374):1243.
PMCID: PMC1124702  PMID: 12446549

Results 1-5 (5)