Search tips
Search criteria

Results 1-2 (2)

Clipboard (0)

Select a Filter Below

more »
Year of Publication
Document Types
1.  Antileishmanial Activity of Some Plants Growing in Algeria: Juglans Regia, Lawsonia Inermis and Salvia Officinalis 
The current study was undertaken to evaluate in vitro the antileishmanial activity of three plants growing wild in Algeria : Juglans regia, Lawsonia inermis and Salvia officinalis. The hydroalcoholic extracts of these plants were tested on the growth of the promastigotes of Leishmania major. The plant extract effects were compared with three controls : CRL1 composed of 1 ml RPMI inoculated with 106 of promastigotes, CRL2 composed of 1 ml RPMI inoculated with 106 of promastigotes and 100 µl of hydroalcoholic solvent, CRL3 composed of 1 ml RPMI inoculated with 106 of promastigotes and 100 µl of Glucantim as a reference drug in the management of leishmaniasis. The results showed that both J. regia and L. inermis extracts reduced the promastigotes number significantly (P<0.01). however, S. officinalis showed a total inhibition of the Leishmania major growth.
PMCID: PMC3777582  PMID: 24146470
anti-leishmanial activity; Leishmania major; Juglans regia; Lawsonia inermis; Salvia officinalis
2.  Effect of Virgin Fatty Oil of Pistacia Lentiscus on Experimental Burn Wound's Healing in Rabbits 
This study aimed to assess the efficiency of the virgin fatty oil of Pistacia lentiscus (PLVFO) for burn wounds healing. It was carried out on 6 adult male New Zealand rabbits. Four burn wounds of deep third degree were made on the back of each animal. The first was not treated and served as control (CRL group); the others were covered immediately after burning procedure by 0.5g of one of the following products: Vaseline gel (VAS group), Madecassol® cream 1% (MAD group) or 1ml of PLVFO (PLVFO group). The treatments were repeated once daily until complete healing. For four days post burns, the percentage of wound contraction was assessed. Also, the different healing times were noted. The results showed that both PLVFO and Madecassol® significantly accelerated wound healing activity compared to wounds dressed with Vaseline and the untreated wounds. However, the level of wound contraction was significantly higher and the healing time was faster in PLVFO group than those of the MAD group, VAS group and CRL group. The different epithelization periods obtained in days were respectively: 30±3.94 (PLVFO group), 33.5±3.78 (MAD group), 34.66±3.88 (VAS group) and 37.16±3.54 (CRL group). We conclude that Pistacia lentiscus virgin fatty oil promotes significantly (p< 0.05) wound contraction and reduces epithelization period in rabbit model.
PMCID: PMC3025617  PMID: 21461154
Virgin fatty oil; Pistacia lentiscus; burn; wound healing; rabbits

Results 1-2 (2)