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1.  Design of a Clinical Information Management System to Support DNA Analysis Laboratory Operation 
The LabDirector system has been developed at the Oregon Health Sciences University to support the operation of our clinical DNA analysis laboratory. Through an iterative design process which has spanned two years, we have produced a system that is both highly tailored to a clinical genetics production laboratory and flexible in its implementation, to support the rapid growth and change of protocols and methodologies in use in the field. The administrative aspects of the system are integrated with an enterprise schedule management system. The laboratory side of the system is driven by a protocol modeling and execution system. The close integration between these two aspects of the clinical laboratory facilitates smooth operations, and allows management to accurately measure costs and performance. The entire application has been designed and documented to provide utility to a wide range of clinical laboratory environments.
PMCID: PMC3206267
5.  Demonstration of a Client/Server System for Remote Diagnosis of Cardiac Arrhythmias 
Health care practitioners are often faced with the task of interpreting complex heart rhythms from electrocardiograms (ECGs) produced by 12-lead ECG machines, ambulatory (Holter) monitoring systems, and intensive-care unit monitors. Usually, the practitioner caring for the patient does not have specialized training in cardiology or in ECG interpretation; and commercial programs that interpret 12-lead ECGs have been well-documented in the medical literature to perform poorly at analyzing cardiac rhythm. We believe that a system capable of providing comprehensive ECG interpretation as well as access to online consultations will be beneficial to the health care system. We present a client-server based telemedicine system capable of providing access to (1) an on-line knowledge-based system for remote diagnosis of cardiac arrhythmias and (2) an on-line cardiologist for real-time interactive consultation using readily available resources on the Internet.
PMCID: PMC2579882
telemedicine; knowledge-based systems; model-based diagnosis; cardiac arrhythmias; Internet
14.  Internet-Based Support for a Collaborative Genome Center to Map Human Chromosome 12 
We will demonstrate a shared database (DB/12) and a set of software tools developed for a genome center to map human chromosome 12. The approach involves an internet-based client-server architecture to support collaborating laboratories at the Albert Einstein College of Medicine and at Yale.
PMCID: PMC2579873
15.  Harnessing SNOMED: A Relational Database Design for the Computerized Patient Record (CPR) 
A CPR model that supports SNOMED cross-references was designed for a relational database query language. The model is compatible with a subsequent migration to an advanced object-oriented database design using predicate logic or a semantic network.
PMCID: PMC2579872
17.  A Pen-Based System for the Psychiatric Emergency Room 
Translating paper based clinical assessment forms to computer based forms for a Psychiatric Emergency Room was facilitated by the use of a computer using Windows for Pen® system and a familiar database. Offering a smooth transition from paper to electronic forms was the primary goal for this busy metropolitan Psychiatric Emergency Room.
PMCID: PMC2579870
19.  Case-Oriented Design of the Radiology Educational Resource 
Digital Case Library (DCL) is a relational database of neuroradiology cases. DCL is a resource for three educational modules: the Case-Based Differential Diagnosis, Teaching Files, and Quiz. The Case-Based Differential Diagnosis module can be searched through the controlled vocabulary of radiologic findings to find images that match feature description. Using the Teaching File module, the user can browse preselected images that are grouped according to pathology, anatomy, and modality. The Quiz module is a self-assessment program that provides the user with randomly selected images with hidden captions.
PMCID: PMC2579868
20.  Simulating the Clinical Care of Patients: A Comprehensive Mathematical Model of Human Pathophysiology 
A comprehensive mathematical model of human pathophysiology has been combined with a clinically realistic computer interface in order to allow users to develop and refine clinical skills. Users apply medical diagnostic and treatment maneuvers that impact patient clinical and cost outcomes. The computer system will critique performance on several levels and allow users to replay the simulation to improve clinical insight.
PMCID: PMC2579867

Results 1-25 (4087)