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1.  A model for community health service development in depressed rural areas in China 
To introduce a model of community health service organization (as implemented in urban areas) to less developed rural areas in China and evaluate the impact of this model on health care utilization.
The intervention involved developing leadership at county level, training rural health practitioners, providing clinical management guidelines and standards, encouraging clinic improvements and providing access to subsidies for public health work. We chose 7 townships and 49 administrative villages in Chongyi County as the intervention sites; 3 townships and 9 administrative villages in Luxi County as the comparison sites. Officers from county health bureaus and postgraduates from School of Public Health, Nanchang University visited each township hospital and village clinic in field together and made observations and interviewed clinic staff.
There was little change in health facilities or workforce in the two areas. However, there was an increase in the use of public health services at township and village level in the intervention sites in Chongyi. In these, the proportion of clinics which had developed a child health (under the age of 3) management system, maternal postpartum visit and chronic disease management increased from 53%, 51% and 47% to 78%, 73%, and 71% respectively. There was no significant change in the comparison sites.
The trial demonstrated that it was feasible to implement a model of community health service delivery that was adapted to depressed rural areas because it required little organizational change, additional funding or personnel. The model had a positive impact on the provision of public health programs, a finding which has implications for efforts to improve access to primary health care in rural China.
PMCID: PMC3548693  PMID: 23244489
Primary health care; Community health services; Rural health; Economically depressed; Public health
2.  Anxiolytic-Like Effects of Compound Zhi Zhu Xiang in Rats 
The purpose of this study was to determine whether compound zhi zhu xiang (CZZX) exerts anxiolytic-like effects in rats. The animals were orally administered CZZX (0.75, 1.5, and 3 g/kg daily) for 10 days and tested in the elevated plus maze (EPM), Vogel conflict test (VCT), and open field. Repeated treatment with CZZX (3 g/kg/day, p.o.) significantly increased the percentage of both entries into and time spent on the open arms of the EPM compared with saline controls. In the VCT, repeated treatment with CZZX (1.5 and 3 g/kg/day, p.o.) significantly increased the number of punished licks. The drug did not change the total entries into the open arms of the EPM or interfere with water consumption or nociceptive threshold, discarding potential confounding factors in the two tests. In the open field, locomotion was not reduced, discarding the possible sedative effect of CZZX. In the binding assay, the binding of [3H] Ro 15-1788 (flumazenil) to the benzodiazepine binding site in washed crude synaptosomal membranes from rat cerebral cortex was affected by CZZX. These data indicate an anxiolytic-like profile of action for CZZX without sedative side effects, and this activity may be mediated by benzodiazepine binding site modulation at γ-aminobutyric acid-A receptors.
PMCID: PMC3368380  PMID: 22690249
3.  Parafalx angioleiomyoma: a case report and review of the literature 
BMJ Case Reports  2009;2009:bcr10.2008.1167.
Angioleiomyomas (ALMs) involving the central nervous system are exceedingly rare, and no ALM involving the parafalx region has ever been clinically reported. We report the first case of ALM involving the parafalx region on its surgical procedure and radiological feature. A 50-year-old man had a 6 month history of frontal headache and occasional seizure attacks. The radiological examination showed a parafalx occupation similar to meningioma. The tumour was very hypointense on T1 weighted magnetic resonance imaging (MRI) and hyperintense on T2 weighted MRI, which enhanced homogeneously with intravenous administration of gadolinium. The tumour was removed totally by sinusoidal transverse scalp incision and bilateral parafalx approach. To our surprise, the tumour was prominently debulked using bipolar shrinkage to coagulate the tumour feeding vessels, resulting in less bleeding during total removal of the tumour.. The lesion was confirmed as ALM by histological examination. The prognosis was good for the patient after surgery during the 18 month follow-up.
PMCID: PMC3029828  PMID: 21785653

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