The title compound, C7H2ClF3O2, was prepared by the chlorination of 3-amino-2,4,5-trifluorobenzoic acid. The carboxyl group is twisted relative to the benzene ring by 6.8 (1)°. In the crystal, pairs of O—H⋯O hydrogen bonds link molecules into typical centrosymmetric carboxylic acid dimers. These dimers are arranged into sheets parallel to (-103).
doi:10.1107/S1600536812049446
PMCID: PMC3588316
PMID: 23476418
The title compound, C5H8ClNO3, was prepared by the nucleophilic substitution reaction of (2S)-2-chloropropanoyl chloride with glycine. The acetate group forms a dihedral angle of 84.6 (1)° with the mean plane of the C—NH—C=O fragment. In the crystal, the molecules are linked by N—H⋯O and O—H⋯O hydrogen bonds, generating a three-dimensional network, which consolidates the crystal packing.
doi:10.1107/S1600536812036720
PMCID: PMC3435838
PMID: 22969684
In the title compound, C29H26N2O4, the benzene ring is twisted by 73.5 (5) and 84.9 (3)° with respect to the mean planes of the two indole ring systems; the mean planes of the indole ring systems are oriented at a dihedral angle of 82.0 (5)°. In the crystal, molecules are linked by pairs of N—H⋯O hydrogen bonds into chains.
doi:10.1107/S1600536812036239
PMCID: PMC3435799
PMID: 22969645
In the title compound, C16H20FN3O3S, the pyrimidine and benzene rings are oriented at a dihedral angle of 38.8 (3)°. An intramolecular C—H⋯O hydrogen bond occurs. The crystal structure is stabilized by O—H⋯N hydrogen bonds. In addition, C—H⋯O interactions are also present.
doi:10.1107/S1600536811049051
PMCID: PMC3239065
PMID: 22199913
In the molecule of the title compound, C15H12ClF2NO3, the quinoline ring system is not planar, the dihedral angle between the pyridine and benzene rings being 3.55 (8)°. In the crystal, intermolecular C—H⋯O hydrogen bonds link the molecules into layers parallel to (101).
doi:10.1107/S160053681104205X
PMCID: PMC3247378
PMID: 22219996
In the title compound, C14H10N2O2, the dihedral angle between the heterocyclic ring system and the phenyl ring is 45.8 (5)°. Weak intermolecular C—H⋯N hydrogen bonding is present in the crystal structure.
doi:10.1107/S1600536811041006
PMCID: PMC3247312
PMID: 22219930
In the title molecule, C23H21NO, the dihedral angle between the planes of the indole ring and naphthalene ring system is 68.8 (5)°.
doi:10.1107/S1600536811016631
PMCID: PMC3120386
PMID: 21754743
The asymmetric unit of the title compound, C16H17FN2O4S, contains three independent molecules, in which the pyrimidine and benzene rings are oriented at dihedral angles of 41.72 (3)°, 26.21 (3)° and 36.49 (3)°. Intramolecular C—H⋯O hydrogen bonds result in the formation of two six- and one seven-membered non-planar rings, which have have twist conformations. In the crystal structure, intermolecular C—H⋯O hydrogen bonds link the molecules.
doi:10.1107/S1600536808013536
PMCID: PMC2961453
PMID: 21202638
In the title compound, C10H6FNO2S, the benzene and thiazolidine rings make a dihedral angle of 7.52 (3)°. Intramolecular C—H⋯O and C—H⋯S hydrogen bonds result in the formation of nearly planar five- and six-membered rings; the adjacent rings are nearly coplanar. In the crystal structure, intermolecular N—H⋯O hydrogen bonds link the molecules.
doi:10.1107/S1600536807068316
PMCID: PMC2960296
PMID: 21201543