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1.  Polyketides from a Marine-Derived Fungus Xylariaceae sp. 
Marine Drugs  2013;11(5):1718-1727.
Eighteen polyketides (1–18) including six citrinin derivatives, two phenol derivatives, one cyclopentenone, two naphthol derivatives, and seven tetralone derivatives were isolated from the culture broth of a marine-derived fungal strain Xylariaceae sp. SCSGAF0086. Five of these compounds (1, 2, 8, 9, and 10) were new, and their structures were determined by spectroscopic methods. Compounds 4, 6, 7, and 17 showed enzyme-inhibitory activities towards several tested enzymes, and 6 and 7 showed strong antifouling activity against Bugula neritina larvae settlement. This is the first time that the antifouling and enzyme-inhibitory activities of these compounds has been reported.
PMCID: PMC3707170  PMID: 23697953
Xylariaceae sp.; polyketide; enzyme-inhibitory activity; antifouling activity
2.  6,7,15,16-Tetra­hydro-5,14-dibutyl­benzo[1,2-c:4,5-c′]diacridine 
The unit cell of the title compound, C36H36N2, contains two independent mol­ecules which are located about inversion centers. In each molecule the quinoline rings are almost planar, with mean deviations of 0.0302 (1) and 0.0173 (1) Å. In the crystal, mol­ecules are linked by C—H⋯π inter­actions into a three-dimensional network.
PMCID: PMC3393907  PMID: 22798772
3.  Ethyl 8-chloro-1-cyclo­propyl-6,7-difluoro-4-oxo-1,4-dihydro­quinoline-3-carboxyl­ate 
In the mol­ecule of the title compound, C15H12ClF2NO3, the quinoline ring system is not planar, the dihedral angle between the pyridine and benzene rings being 3.55 (8)°. In the crystal, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into layers parallel to (101).
PMCID: PMC3247378  PMID: 22219996
4.  6-Benzyl-6,7-dihydro-5H-pyrrolo­[3,4-b]pyridine-5,7-dione 
In the title compound, C14H10N2O2, the dihedral angle between the heterocyclic ring system and the phenyl ring is 45.8 (5)°. Weak inter­molecular C—H⋯N hydrogen bonding is present in the crystal structure.
PMCID: PMC3247312  PMID: 22219930

Results 1-4 (4)