Previous studies on occupational risk for chronic kidney disease (CKD) have analyzed a limited
range of occupations and focused on nephrotoxins. The primary purpose of this study was to examine
the relative risk for the occurrence of CKD between different occupations in the US adult
Materials and methods:
This was a population-based survey study of 91,340 participants in the US, who completed the
National Health Interview Survey, 2004 through 2008. The outcome variable, CKD, was defined as
having weakening/failing kidneys in the past 12 months, as diagnosed by a physician. The predictor
variable, occupation, was obtained using the census occupational codes, regrouped according to North
American Industrial Classification System.
After controlling for age, gender, hypertension, and education, and with the category Life,
Physical, and Social Science Occupations as a reference group, the likelihood of developing CKD was
4.3 times higher in respondents working in Building, Grounds Cleaning and Maintenance Occupations,
4.4 times higher in Healthcare Practitioners and Technical Occupations, 4.7 times higher in
Transportation and Material Moving Occupations and in Computer and Mathematical Occupations, 4.8
times higher in Production Occupations, 5.3 times higher in Food Preparation and Serving Related
Occupations, and 6.1 times higher in Healthcare Support Occupations and in Legal Occupations.
This study identified occupation groups in US adult population with increased risk for CKD.
Alleviation of workplace stress is suggested as a goal for behavioral intervention in high-risk