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1.  Presentation of two patients with malignant granulosa cell tumors, with a review of the literature 
Granulosa cell tumors (GCTs) of the ovary account for 2 to 5 of ovarian malignancies. We present two patients with malignant ovarian adult GCT. In one patient, a combination of bleomycin, etoposide, and cisplatin was effective after initial surgery for malignant GCT. In the other, an aromatase inhibitor was effective for recurrent malignant GCT. We also review the literature for further management of this tumor. Because GCT of the ovary is rare, it will be necessary to elucidate the clinical phenotype and establish treatment protocols by accumulating and analyzing more patients.
doi:10.1186/1477-7819-10-185
PMCID: PMC3490972  PMID: 22963202
Ovarian malignant granulosa cell tumor; BEP combination therapy; Aromatase inhibitor

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