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1.  Retinal image registration and comparison for clinical decision support 
The Australasian Medical Journal  2012;5(9):507-512.
Background
For eye diseases, such as glaucoma and age-related macular degeneration (ARMD), involved in long-term degeneration procedure, longitudinal comparison of retinal images is a common step for reliable diagnosis of these kinds of diseases.
Aims
To provide a retinal image registration approach for longitudinal retinal image alignment and comparison.
Method
Two image registration solutions were proposed for facing different image qualities of retinal images to make the registration methods more robust and feasible in a clinical application system.
Results
Thirty pairs of longitudinal retinal images were used for the registration test. The experiments showed both solutions provided good performance for the accurate image registrations with efficiency.
Conclusion
We proposed a set of retinal image registration solutions for longitudinal retinal image observation and comparison targeting a clinical application environment.
doi:10.4066/AMJ.2012.1364.
PMCID: PMC3477780  PMID: 23115586
Retinal image registration; Glaucoma; ARMD; clinical decision support

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