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1.  XXIV World Allergy Congress 2015 
Lee, Heung-Man | Park, Il-Ho | Shin, Jae-Min | Yoon, Hyun-Sun | Park, Gyeong Yul | Zeher, Margit | Matsui, Katsuhiko | Tamai, Saki | Ikeda, Reiko | Suri, Drsushil | Suri, Dranu | Arani, Marzieh Heidarzadeh | Lubis, Azwin | Endaryanto, Anang | Koga, Shinichiro | Suk, Lee Ju | Tsuzuki, Yasunobu | Kim, Seo Hyeong | Shin, Jung U. | Noh, Ji Yeon | Jin, Shan | Jin, Shan | Lee, Hemin | Lee, Jungsoo | Park, Chang Ook | Lee, Kwang Hoon | Lee, Kwang Hoon | Tepetam, Fatma Merve | Park, Chun Wook | Son, Jee Hee | Cho, Soo Ick | Cho, Yong Se | Byun, Yun Sun | Yang, Yoon Seok | Chung, Bo Young | Kim, Hye One | Cho, Hee Jin | Katada, Yoshinori | Tanaka, Toshio | Nakabayashi, Akihiko | Nishida, Koji | Aoyagi, Kenichi | Tsukamoto, Yuki | Konma, Kazushi | Matsuura, Motoo | Park, Jung-Won | Harada, Yoshinori | Jeong, Kyoung Yong | Yura, Akiko | Yoshimura, Maiko | Kyung, Tae-Suk | Kim, Young Hyo | Park, Chang-Shin | Jang, Tae Young | Heo, Min-Jeong | Jung, Ah-Yeoun | Yang, Seung-Chan | Kim, Hye One | Cho, Yong Se | Byun, Yun Sun | Yang, Yoon Seok | Chung, Bo Young | Son, Jee Hee | Park, Chun Wook | Cho, Hee Jin | Pfaar, Oliver | Sager, Angelika | Agarwal, Amit | Singh, Meenu | Chatterjee, Bishnupda | Chauhan, Anil | Striz, Ilja | Cecrdlova, Eva | Petrickova, Katerina | Kolesar, Libor | Sekerkova, Alena | Svachova, Veronika | Petricek, Miroslav | Kwon, Hyuck Hoon | Kim, Kyu Han | Kumar, Suman | Manzon, Lou Ver Leigh Arciaga | Andaya, Pilar Agnes Gonzalez | Lew, Bark-Lynn | Oh, Youngjun | Suh, Dongwoo | Sim, Woo-Young | Jeong, Kyoung Yong | Yi, Myung-Hee | Son, Mina | Lyu, Dongpyo | Lee, Jae-Hyun | Yong, Tai-Soon | Hong, Chein-Soo | Park, Jung-Won | Jeong, Kyoung Yong | Yi, Myung-Hee | Son, Mina | Lyu, Dongpyo | Lee, Jae-Hyun | Yong, Tai-Soon | Hong, Chein-Soo | Park, Jung-Won | Siavashi, Mohammadreza | Yun, Hey Suk | Kang, Ha-Na | Oh, Jae-Won | Choi, Young Jin | Oh, Jae-Won | Choi, Young Jin | Kang, Ha-Na | Sentsova, Tatiana | Vorozhko, Ilya | Chernyak, Olga | Revyakina, Vera | Timopheeva, Anna | Donnikov, Andrey | Sentsova, Tatiana | Vorozhko, Ilya | Chernyak, Olga | Revyakina, Vera | Timopheeva, Anna | Lee, Ji Hyun | Park, Young Min | Choi, Sang Soo | Han, Kyung Do | Jung, Han Mi | Youn, Young Hoon | Lee, Jun Young | Park, Yong Gyu | Lee, Seung-Hwan | Li, Jing | Feng, Mulin | Roponen, Marjut | Schaub, Bianca | Wong, Gary W. K. | Yang, Zhaowei | Choi, Young Jin | Kang, Ha-Na | Oh, Jae-Won | Sun, Baoqing | Zheng, Peiyan | Park, Yoon-Sung | Son, Sang Wook | Kose, Sukran | Kiraz, Kemal | Yalcin, Arzu Didem | Yune, Sehyo | Paeng, Jae-Won | Oh, Mi-Jung | Lee, Byung-Jae | Choi, Dong-Chull | Lim, Young Hee | Ha, Kyoung Won | Lee, Jin-Young | Yamamoto-Hanada, Kiwako | Narita, Masami | Futamura, Masaki | Ohya, Yukihiro | Kim, Jihyun | Choi, Jinwha | Kim, Kwanghoon | Choi, Jaehee | Ahn, Kangmo | Chang, Sun-Ho/Brian | Li, Lisha | Adachi, Yu-Ichi | Kanatani, Kumiko Tsuji | Narabayashi, Shigeyuki | Okafuji, Ikuo | Tanaka, Yuya | Tsuruta, Satoru | Takamatsu, Nobue | Kim, Soo Whan | Kim, Do Hyun | Yoon, Jong-Seo | Kim, Jin Tack | Kim, Hwan Soo | Chun, Yoon Hong | Kim, Hyun Hee | Won, Sul Mui | Hon, Kam Lun E. | Chow, Chung Mo | Leung, Ting Fan | Kim, Do Hyun | Kim, Soo Whan | Esguerra, Gemmalyn | Resurreccion, Emily | Kionisala, Kristine Elisa | Dela Cruz, Jenni Rose | Imran, Muhammad | Choe, Yun Seon | Kim, Kyu Han | Choi, Mira | Kim, Byung Soo | Lee, Hyun-Joo | Kim, Jeong-Min | Kim, Jeong-Min | Kim, Gun-Wook | Mun, Je-Ho | Mun, Je-Ho | Kim, Hoon-Soo | Song, Margaret | Ko, Hyun-Chang | Ko, Hyun-Chang | Kim, Moon-Bum | Yoon, Sun-Young | Kandhare, Amit | Yahiro, Noriko | Agarwal, Amit | Singh, Meenu | Kaur, Jasleen | Pawankar, Ruby | Pant, Pankaj | Singh, Sukhmanjeet | Kim, Hwan Soo | Yoon, Jong-Seo | Won, Sul Mui | Chun, Yoon Hong | Kim, Jin Tack | Kim, Hyun Hee | Kim, Hwan Soo | Won, Sul Mui | Chun, Yoon Hong | Yoon, Jong-Seo | Kim, Hyun Hee | Kim, Jin Tack | Kampitak, Thatchai | Kim, So Min | Lee, Hyun Joo | Kim, Hei Sung | Lee, Jeong Deuk | Cho, Sang Hyun | Godse, Kiran | Soekarno, Juwita | Ratnasari, Sarie | Datau, E. Alwi | Surachmanto, Eko | Matheos, JC | Leung, Ting Fan | Kwok, Jamie Sui-Lam | Tung, Christine Kit-Ching | Tang, Man Fung | Tsui, Stephen Kwok-Wing | Wong, Gary WK | Hon, Kam Lun Ellis | Tam, Wing Hung | Sy, Hing Yee | Lee, Sohee | Shin, Hyun-Woo | Lee, Mingyu | Kim, Dae Woo | Khalmuratova, Roza | Kim, Mi Yeoung | Jeong, Jaewon | Park, Chansun | Wai, Christine Yee Yan | Leung, Patrick S. C. | Leung, Nicki Y. H. | Chu, Ka Hou | Lee, Hee Seon | Lee, Kyung Eun | Hong, Jung Yeon | Kim, Mi Na | Kim, Min Jung | Kim, Yoon Hee | Sol, In Suk | Yoon, Seo Hee | Kim, Kyung Won | Sohn, Myung Hyun | Kim, Kyu-Earn | Kim, Ji Hye | Park, Hae-Sim | Shin, Yoo Seob | Ye, Young Min | Seo, Daehong | Yoon, Moon Gyeong | Lee, Young Mok | Seo, Daehong | Kim, Ji Hye | Lee, Young-Mok | Ye, Young Min | Park, Hae-Sim | Ban, Ga Young | Cho, Kumsun | Kim, Seung-Hyun | Kwon, Yong Eun | Yoon, Moon Gyeong | Kim, Ji Hye | Shin, Yoo Seob | Ye, Young Min | Nahm, Dong-Ho | Park, Hae-Sim | Andaya, Pilar Agnes Gonzalez | Andaya, Pilar Agnes Gonzalez | Ban, Ga Young | Jung, Chang Gyu | Lee, Seung-Ihm | Le Pham, Duy | Suh, Dong-Hyeon | Yang, Eun-Mi | Ye, Young Min | Shin, Yoo Seob | Park, Hae-Sim | Wang, Wan Jun | Xian, MO | Xie, Yan Qing | Zheng, Jing Ping | Li, Jing | Savilahti, Emma Merike | Mäkitie, Outi | Kukkonen, Anna Kaarina | Andersson, Sture | Viljakainen, Heli | Savilahti, Erkki | Kuitunen, Mikael | Godse, Kiran | Le Pham, Duy | Ban, Ga Young | Kim, Seung-Hyun | Yang, Eun-Mi | Park, Hae-Sim | Lee, Ji-Ho | Chwae, Yong-Joon | Chin, Li-Ming | Shieh, Chi-Chang | Kim, Ji Hye | Yoo, Hye-Soo | Yoon, Moon Gyeong | Ban, Ga Young | Ban, Ga Young | Shin, Yoo Seob | Ye, Young Min | Park, Hae-Sim | Sung, Myong Soon | Choi, Jin Uck | Kim, Sung Won | Hwang, Yong Jin | Park, Arum | Lee, Eun | Yang, Song-I | Cho, Hyun-Ju | Yu, Jinho | Lee, Dong Hun | Kim, Eun Ju | Kim, Yeon Kyung | Doh, Eun Jin | Eun, Hee Chul | Chung, Jin Ho | Lee, Young Mee | Jin, Seon Pil | Li, Xingnan | Kaminski, Naftali | Wenzel, Sally | Bleecker, Eugene | Meyers, Deborah | Huasong, Zeng | Mo, Ji-Hun | Samivel, Ramachandran | Kim, Eun-Hee | Kim, Ji-Hye | Bae, Jun-Sang | Chung, Young-Jun | Kim, Dae Woo | Lee, Eun | Lee, Si Hyeon | Kim, Young-Ho | Cho, Hyun-Ju | Yu, Ho-Sung | Kang, Mi-Jin | Yang, Song-I | Jung, Young-Ho | Kim, Hyung Young | Seo, Ju-Hee | Kim, Byoung-Ju | Kim, Hyo-Bin | Lee, So-Yeon | Kwon, Ho-Jang | Hong, Soo-Jong | Palikhe, Sailesh | Park, Hae-Sim | Kim, Seung-Hyun | Kim, Ji Hye | Yang, Eun-Mi | Sibunruang, Suda | Klaewsongkram, Jettanong | Sentsova, Tatiana | Vorozhko, Ilya | Timopheeva, Anna | Chernyak, Olga | Revyakina, Vera | Sokolnikov, Andrey | Nisihino, Makoto | Okada, Yu | Yanagida, Noriyuki | Ebisawa, Motohiro | Sato, Sakura | Ogura, Kiyotake | Asaumi, Tomoyuki | Nagakura, Kenichi | Manabe, Tetsuharu | Unno, Hirotoshi | Rodrigues, Pedro M. | Schrama, Denise | Mohamed, Gadija | Hüsselmann, Lizex | Hüsselmann, Lizex | Ndimba, Bongani | Shim, Jae-Uoong | Koh, Young Il | Rhee, Joon Haeng | Jeong, Ji-Ung | Van Nguyen, Dinh | Chu, Hieu Chi | Tran, Mui Thi | Vidal, Christopher | Fernando, Suran | Van Nunen, Sheryl | Van Than, Sy | Feng, Mulin | Li, Jing | Kim, Dong-Kyu | Hong, Seung-No | Eun, Kyoung Mi | Jin, Hong Ryul | Kim, Dae Woo | Bao, Jun | Bao, Yi-Xiao | Podder, Sanjoy | Kumar, Goutam | Dutta, Shampa | Ghosh, Amlan | Saha, Goutam Kumar | Podder, Sanjoy | Gupta, Salil Kumar | Trinh, Tu/Hoang Kim | Shin, Yoo Seob | Park, Hae-Sim | Liu, Jing-Nan | Le Pham, Duy | Ko, Hyun-Chang | Kim, Byung Soo | Kim, Moon-Bum | Özbudak, Ömer | Üzer, Fatih | Al-Ahmad, Mona | Alowayesh, Maryam | Carroll, Norman | Singh, Anand Bahadur | Pérez-Llano, Yordanis | Lorenzo, María Del Carmen Luzardo | González, Wendy Ramírez | Cruz, Carlos Calcines | Quintana, Rady Laborde | Morejón, Alain | Bourg, Virgilio | Stoker, Marilé Hechavarría | Bae, Jun-Sang | Samivel, Ramachandran | Kim, Eun-Hee | Kim, Ji-Hye | Mo, Ji-Hun | Hanaoka, Keiko | Hide, Michihiro | Tanaka, Akio | Hiragun, Makiko | Kawai, Mikio | Kim, Kwanghoon | Kim, Hye-Young | Kim, Jihyun | Ahn, Kangmo | Han, Youngshin | Kim, Gun-Wook | Ko, Hyun-Chang | Kim, Byung Soo | Kim, Moon-Bum | Song, Margaret | Matsubara, Takeshi | Iwamoto, Hiroshi | Nakazato, Yuki | Namba, Kazuyoshi | Takeda, Yasuhiro | Lee, Jae Hoon | Bae, Woo Yong | De Schryver, Els | Calus, Lien | Gevaert, Philippe | Van Zele, Thibaut | Bachert, Claus | Mori, Akio | Kouyama, Satoshi | Yamaguchi, Miyako | Iijima, Yo | Abe-Ohtomo, Akemi | Hayashi, Hiroaki | Watai, Kentaroh | Mitsui, Chihiro | Oshikata, Chiyako | Sekiya, Kiyoshi | Tsuburai, Takahiro | Ohtomo, Mamoru | Fukutomi, Yuma | Taniguchi, Masami | Kang, Ju Wan | Kim, Jeong Hong | Kim, Jeong Hong | Lee, Keun-Hwa | Lee, Hye-Sook | Hong, Seong-Chul | Lee, Jaechun | Seo, Ji Won | Lee, Jae Hoon | Bae, Woo Yong | Kuznecovs, Ivans Sergejs | Kuznecova, Galina | Bergmann, Karl-Christian | Zuberbier, Torsten | Salame, Joseph | Sehlinger, Torsten | Bölke, Georg | Kim, Yoo Suk | Chang, Jung Hyun | Kim, Jeong Hong | Kang, Ju Wan | Hong, Seung-No | Han, Doo Hee | Rhee, Chae-Seo | Ko, Young-Joo | Kim, Young Hyo | Kim, Dae-Young | Jang, Tae Young | Yokooji, Tomoharu | Hirano, Taiki | Matsuo, Hiroaki | Kuznecova, Galina | Kuznecovs, Ivans Sergejs | Wani, Roohi Rasool | Syed, Shafia Alam | Hassan, Ghulam | Gul, Ayaz | Nissar, Saniya | Shah, Zaffar Amin | Pereira, Marilyn Urrutia | Fernandez, Carmen | Sole, Dirceu | Neto, Herberto Jose Chong | Acosta, Veronica | Cepeda, Alfonso Mario | Castello, Mirta Alvarez | Almendarez, Claudia | Saenz, Jose Santos Lozano | Sisul, Juan C. | Filho, Nelson Rosario | Castillo, Antonio | Rostan, Marylin Valentin | Avila, Jennifer | Badellino, Hector | Manotas, Maria Carolina | Almarales, Raúl Lázaro Castro | León, Mayda González | Kim, Woo Kyung | Yoon, Hae-Sun | Kobayashi, Takehito | Noguchi, Tooru | Soma, Tomoyuki | Nakagome, Kazuyuki | Nakamoto, Hidetomo | Kita, Hirohito | Nagata, Makoto | Pereira, Marilyn Urrutia | Sole, Dirceu | Neto, Herberto Jose Chong | Cepeda, Alfonso Mario | Almarales, Raúl Lázaro Castro | Sisul, Juan C. | Rostan, Marylin Valentin | Badellino, Hector | Avalos, Miguel Alejandro Medina | Castillo, Antonio | Almendarez, Claudia | Filho, Nelson Rosario | Silot, Caridad Sanchez | Avila, Jennifer | Rodriguez, Felicia Berroa | Saenz, Jose Santos Lozano | Castello, Mirta Alvarez | Fernandez, Carmen | Soh, Wai Tuck | Jacquet, Alain | Ruxrungtham, Kiat | Nony, Emmanuel | Le Mignon, Maxime | Lee-Wong, Mary | McClelland, Suzanne | McClelland, Suzanne | Silverberg, Nanette B. | Song, Christian E. | Yang, Zhaowei | Zhang, Jiukai | Zheng, Wentao | Zhong, Nanshan | Li, Jing | Bae, Jung Ho | Cho, Young Joo | Kim, Joo Yeon | Vourdas, Dimitrios | Grigoreas, Christos | Petalas, Konstantinos | Zhang, Yuan | Shin, Seung-Heon | Ye, Mi-Kyung | Kim, Jeong-Kyu | Feng, Yong | Shang, Yunxiao | Seo, Sungchul | Choung, Ji Tae | Kim, Dohyeong | Yoo, Young | Lim, Hyunwook | Zhu, Wenjing | Liu, Chuanhe | Sha, Li | Chang, Li | Zhao, Min | Zhao, Linqing | Qian, Yuan | Chen, Yuzhi | Kim, Min-Hye | Cho, Young Joo | Rho, Mina | Kim, Jung-Won | Kang, Yeon-Mi | Yum, Kyung-Eun | Choi, Hyeon-Il | Choi, Jun-Pyo | Park, Han-Ki | Min, Taek-Ki | Pyun, Bok-Yang | Kim, Yoon-Keun | Wang, Xueyan | Kim, Woo Kyung | Nam, Yu Ran | Nam, Joo Hyun | Kim, Jung-Won | Kim, Min-Hye | Rho, Mina | Kang, Yeon-Mi | Yum, Kyung-Eun | Choi, Hyeon-Il | Choi, Jun-Pyo | Park, Han-Ki | Min, Taek-Ki | Cho, Young Joo | Pyun, Bok-Yang | Kim, Yoon-Keun | Narita, Hiroshi | Hirose, Junko | Kizu, Kumiko | Matsunaga, Ayu | Li, Jingyun | Zhang, Yuan | Zhang, Luo | Choi, Yean Jung | Shin, Hye Lim | Yang, Song-I | Lee, So-Yeon | Kwon, Sung-Ok | Jung, Young-Ho | Kwon, Ji-Won | Kim, Hyung Young | Seo, Ju-Hee | Kim, Byoung-Ju | Kim, Hyo-Bin | Oh, Se-Young | Kwon, Ho-Jang | Lee, Eun | Kang, Mi-Jin | Hong, Soo-Jong | Lee, Yun-Jeong | Kim, Joonil | Choi, Joon Young | Kang, Ji Young | Kim, Seok Chan | Kim, Sei Won | Kim, Seung Joon | Kim, Young Kyoon | Rhee, Chin Kook | Lee, Hea Yon | Lee, Hwa Young | Lee, Sook Young | Koh, Tae Kyung | Kim, Sung Wan | Lee, Kun Hee | Kwon, Chul | Jo, Joong-Saeng | Dong, Sung-Hwa | Byun, Young Seok | Song, Charles | Kang, Ji Young | Lee, Hwa Young | Kim, In Kyoung | Kim, Sei Won | Rhee, Chin Kook | Kim, Seung Joon | Kim, Seok Chan | Lee, Sook Young | Kim, Young Kyoon | Kwon, Soon Seog | Choi, Joon Young | Park, Pona | Jin, Hong Ryul | Kim, Dong-Kyu | Kim, Dae Woo | Hogenkamp, Astrid | Knippels, Leon | Van Esch, Betty C.a.m. | Van Bilsen, Jolanda | Jeurink, Prescilla V. | Gros, Marjan | Garssen, Johan | Smit, Joost J. | Pieters, Raymond H. H. | Kim, Boo-Young | Kim, Soo Whan | Lleonart, Ramon | Lay, Christophe | Benamor, Kaouther | Chen, Chua Mei | Knol, Jan | Chew, Charmaine | Chongsrisawat, Voranush | Goh, Anne | Chiang, Wen Chin | Rao, Rajeshwar | Chaithongwongwatthana, Surasith | Khemapech, Nipon | Yhi, Ji Young | Kim, Sang-Heon | Park, Dong Won | Moon, Ji-Yong | Kim, Tae Hyung | Sohn, Jang Won | Shin, Dong Ho | Yoon, Ho Joo | Cho, Seok Hyun | Kim, Sang-Heon | Moon, Ji-Yong | Lee, Jae-Hyun | Ban, Ga Young | Kim, Sujeong | Kim, Mi-Ae | Kim, Joo-Hee | Kim, Min-Hye | Park, Chan-Sun | Kwon, Hyouk-Soo | Kwon, Jae-Woo | Jung, Jae Woo | Kang, Hye-Ryun | Park, Jong-Sook | Kim, Tae-Bum | Park, Heung Woo | Cho, You Sook | Yoo, Kwang-Ha | Oh, Yeon-Mok | Lee, Sang-Rok | Julge, Kaja | Vasar, Maire | Vasar, Maire | Voor, Tiia | Rebane, Tiina | Kim, Yu Jin | Lee, Sang Min | Kang, Shin Myung | Kim, Sojeong | Kyung, Sun Young | Jeong, Sung Hwan | Park, Jeong-Woong | Hwang, Hyunjung | Seon, Yong Han | Park, Sanghui | Lee, Sang Pyo | Iordache, Marius | Jeong, Yeongsang | Eun, Sohee | Choi, Byung Min | Choung, Ji Tae | Seo, Wonhee | Zhang, Liang | Pawankar, Ruby | Nonaka, Manabu | Hayashi, Miyuki | Yamanishi, Shingo | Suzaki, Harumi | Itoh, Yasuhiko | Watanabe, So | Kobayashi, Hitome | Zotter, Zsuzsanna | Farkas, Henriette | Varga, Lilian | Veszeli, Nora | Imreh, Eva | Kovacs, Gabor | Nallbani, Marsel | Zheleznov, Semen | Urzhumtseva, Galina | Petrova, Natalia | Sarsaniia, Zhanna | Didkovskii, Nikolai | Zuberbier, Torsten | Gerdabi, Nader Dashti | Khodadadi, Ali | Abdoli, Zahra | Ghafourian, Mehri | Assarehzadegan, Mohammad Ali | Ghorban, Khodayar | Kim, Hyo-Bin | Zhou, Hui | Kim, Jeong Hee | Habre, Rima | Bastain, Theresa | Gilliland, Frank | Bae, Jong-Wook | Han, Kyu-Hyung | Jee, Young-Koo | Choi, Misoo | Hong, Seung-Phil | Kim, Seung-Hyun | Kim, Hee-Kyoo | Choi, Gil-Soon | Heo, Jeonghoon | Kim, Young-Ho | Park, Eun-Kee | Inoue, Takashi | Ogura, Kiyotake | Yanagida, Noriyuki | Unno, Hirotoshi | Nagakura, Kenichi | Manabe, Tetsuharu | Asaumi, Tomoyuki | Sato, Sakura | Okada, Yu | Ebisawa, Motohiro | Kim, Min-Gu | Cho, You Sook | Kim, Tae-Bum | Moon, Hee-Bom | Kim, Jung-Hyun | Kim, Hyo-Jung | Park, So-Young | Seo, Bomi | Kwon, Hyouk-Soo | Lee, Jaemoon | Lee, Taehoon | Yoo, Hye-Soo | Kim, Jieun | Kim, Inok | Kim, Haejin | Chang, Younhee | Park, Hae-Sim | Lee, Sooyoung | Lee, Sooyoung | Kuzume, Kazuyo | Koizumi, Munemitsu | Nishimura, Koji | Okamoto, Michiko | Kim, Seung-Hyun | Ye, Young Min | Hur, Gyu Young | Park, Hae-Sim | Kim, Sang-Heon | Jee, Young-Koo | Kim, Seung-Hyun | Choi, Hyunna | Ye, Young Min | Park, Hae-Sim | Van Khanh, Bui | Chu, Hieu Chi | Nguyet, Nguyen Nhu | Phuong, Nguyen Hoang | Roh, Joo Young | Kim, Hyun Jeong | Kim, Jung Eun | Lew, Bark-Lynn | Lee, Kyung Ho | Hong, Seung-Phil | Jang, Yong Hyun | Park, Kui Young | Seo, Seong Jun | Bae, Jung Min | Choi, Eung Ho | Suhr, Ki Beom | Lee, Seung Chul | Ko, Hyun-Chang | Park, Young Lip | Son, Sang Wook | Seo, Young Jun | Lee, Yang Won | Cho, Sang Hyun | Park, Chun Wook | Lee, Kun Hee | Kim, Sung Wan | Chu, Chia-Yu | Aw, Derrick | Ye, Young-Min | Bader, Giovanni | Dolfi, Fabrizio | Oliveira, Nathalie | Choi, Jae Chol | Jung, Jae Woo | Kang, Hye-Ryun | Kim, Kijeong | Choi, Byoung Whui | Shin, Jong Wook | Jung, Jae Woo | Choi, Jae Chol | Park, In Won | Choi, Byoung Whui | Kim, Jae Yeol | Lee, Jin-Young | Ha, Kyoung Won | Jeung, Yun-Jin | Yune, Sehyo | Lee, Byung-Jae | Choi, Dong-Chull | Oh, Mi-Jung | Lim, Young Hee | Lee, Eui Jun | Suh, Dongin | Suh, Dongin | Woo, Sung-Il | Woo, Sung-Il | Cho, Hwa Jin | Cho, Hwa Jin | Chung, Eun Hee | Chung, Eun Hee | Chung, Soo Youn | Shah, Ashok | Gera, Kamal | Ha, Kyoung Won | Oh, Mi-Jung | Lim, Young Hee | Yune, Sehyo | Paeng, Jae-Won | Jang, Mi-Jin | Lee, Byung-Jae | Choi, Dong-Chull | Lee, Jin-Young | Jang, Mi-Jin | Paeng, Jae-Won | Jeung, Yun-Jin | Lim, Young Hee | Oh, Mi-Jung | Ha, Kyoung Won | Lee, Byung-Jae | Choi, Dong-Chull | Yune, Sehyo | Lee, Jin-Young | Ito, Takahiro | Lee, Jin-Young | Yune, Sehyo | Lee, Byung-Jae | Choi, Dong-Chull | Jang, Mi-Jin | Paeng, Jae-Won | Kim, Young Eun | Kim, Young Nam | Lee, Yongseok | Kim, Jihye | Lee, Hwa Young | Lee, Sook Young | Kwon, Soon Seog | Kim, Young Kyoon | Rhee, Chin Kook | Kim, Sei Won | Lee, Hea Yon | Choi, Joon Young | Kim, In Kyoung | Aranzabal, Maria Ascension | Joral, Alejandro | Lizarza, Susana | Echenagusia, Miguel | Lasa, Eva Maria | Navarro, Jose Antonio | Jo, Eun-Jung | Jang, Sun-Mi | Song, Seung-Eon | Na, Hae-Jung | Kim, Chang-Hoon | Lee, Woo-Seop | Park, Hye-Kyung | Miyauchi, Sachiko | Uchida, Yoshitaka | Soma, Tomoyuki | Yamazaki, Susumu | Noguchi, Toru | Kobayashi, Takehito | Nakagome, Kazuyuki | Nagata, Makoto | Oh, Hea Lin | Kim, Do Kyun | Suh, Dongin | Koh, Young Yull | Lee, Jin-Young | Lee, Byung-Jae | Choi, Dong-Chull | Paeng, Jae-Won | Jang, Mi-Jin | Kim, Jihye | Kim, Young Nam | Yune, Sehyo | Kim, Sang-Hoon | Sohn, Jang Won | Yoon, Ho Joo | Shin, Dong Ho | Lee, Jae Hyung | Lee, Byoung Hoon | Kim, Youn-Seup | Park, Jae-Seuk | Jee, Young-Koo | Kim, Sang-Heon | Lee, Jin-Young | Paeng, Jae-Won | Jang, Mi-Jin | Choi, Dong-Chull | Lee, Byung-Jae | Lee, Yongseok | Kim, Young Eun | Yune, Sehyo | Yoon, Jisun | Zhang, Li | Cai, Xuxu | Feng, Yong | Yoon, Jong-Seo | Jeong, Kyunguk | Yoo, Hye-Soo | Lee, Sooyoung | Lee, Sooyoung | Lee, Hae-Jin | Lee, Noo Ri | Kim, Bo-Kyung | Jung, Minyoung | Kim, Dong Hye | Moniaga, Catharina S. | Kabashima, Kenji | Choi, Eung Ho | Yanagida, Noriyuki | Sato, Sakura | Sugizaki, Chizuko | Ebisawa, Motohiro | Kiehm, Jamie | Ponda, Punita | Farzan, Sherry | Weiss, Jared | Elera, Claudia | Destio, Catherine | Sison, Cristina | Lee, Annette | Ri, Soo Hyun | Lim, Chang Hoon | Pulido, Iñaki Izquierdo | Taubel, Jorg | Ferber, Georg | Masdeu, Eva Santamaria | Khayatzadeh, Alireza | Movahedi, Masoud | Ebisawa, Motohiro | Gharagozlou, Mohammad | Atasoy, Ulus | Techasintana, Patsharaporn | Gubin, Matt | Glascock, Jacqueline | Ridenhour, Suzanne | Magee, Joseph | Filho, Nelson Rosario | Neto, Herberto Jose Chong | Wandalsen, Gustavo Falbo | Dela Bianca, Ana Caroline | Aranda, Carolina | Sole, Dirceu | Mallol, Javier | Garcia-Marcos, Luis | Garcia-Marcos, Luis | Toh, Jennifer | Lee, Yoomie | Huang, Joyce | Jerschow, Elina | Shliozberg, Jenny | Satitsuksanoa, Pattraporn | Suratannon, Narissara | Wongpiyabovorn, Jongkonnee | Chatchatee, Pantipa | Ruxrungtham, Kiat | Jacquet, Alain | Yang, Min Suk | Lee, Jin Yong | Kim, Ja Yeun | Park, Han-Ki | Kim, Ju-Young | Song, Woo-Jung | Kang, Hye-Ryun | Park, Heung Woo | Chang, Yoon-Seok | Cho, Sang-Heon | Min, Kyung-up | Park, Chang-Han | Chang, Suk-Il | Song, Sook-Hee | Kim, Si-Heon | Choi, Gil-Soon | Kim, Su-Chin | Kim, Ji Hye | Ban, Ga Young | Shin, Yoo Seob | Park, Hae-Sim | Ye, Young Min | Hwang, Yoon Ha | Sim, Da Woon | Park, Kyung Hee | Park, Kyung Hee | Park, Hye Jung | Park, Hye Jung | Park, Jung-Won | Park, Jung-Won | Lee, Jae-Hyun | Lee, Jae-Hyun | Allen, Katrina | Beck, Cara | Koplin, Jennifer | Matheson, Melanie | Tang, Mimi | Ponsonby, Anne-Louise | Gurrin, Lyle | Dharmage, Shyamali | Wake, Melissa | Mcwilliam, Vicki | Liu, Xiaoying | Wang, Jing | Xiang, Li | Wang, Qun | Lee, Ji-Eun | Kim, Dong-Young | Rhee, Chae-Seo | Rhee, Chae-Seo | Vazquez-Nava, Francisco | Cho, Sang-Heon | Jeong, Jaewon | Perng, Diahn-Warng | Price, David | Neira, Glenn | Lin, Jiangtao | Semernik, Olga | Kim, Ha-Su | Jung, Jin-a | Jung, Ji-in | Miao, Qing | Xiang, Li | Cho, Sang-Heon | Jeong, Jaewon | Perng, Diahn-Warng | Lin, Jiangtao | Price, David | Neira, Glenn | Lee, Hyun Young | Park, Hae-Sim | Ye, Young Min | Kim, Su Chin | Farrokhi, Shokrollah | Gheiby, Mohammadkazem | Kim, Sang-Heon | Park, Heung Woo | Kim, Sang-Hoon | Jee, Young-Koo | Park, Sunjoo | Moon, Keun Ai | Kwon, Hyouk-Soo | Kim, Tae-Bum | Cho, You Sook | Moon, Hee-Bom | Lee, Kyoung Young | Hong, Gyong Hwa | Ha, Eun Hee | Han, Heejae | Park, Hye Jung | Park, Yoon Hee | Kim, Yoon-Jo | Lee, Kangtaek | Park, Jung-Won | Lee, Jae-Hyun | Slavyanskaya, Tatiana | Derkach, Vladislava | Park, Hye Jung | Hong, Chein-Soo | Lee, Jae-Hyun | Kim, Sungryeol | Park, Kyung Hee | Lee, Choong-Kun | Kang, Beodeul | Beom, Seung-Hoon | Shin, Sang Joon | Jung, Minku | Park, Jung-Won | Kim, Eun-Hee | Kim, Ji-Hye | Mo, Ji-Hun | Chung, Young-Jun | Kim, Mi-Ae | Park, Hae-Sim | Yoon, Moon Gyeong | Lee, Young-Soo | Kim, Ji Hye | Ban, Ga Young | Yoo, Hye-Soo | Shin, Yoo Seob | Ye, Young Min | Nahm, Dong-Ho | Miao, Qing | Xiang, Li | Li, Ying-Ji | Shimizu, Takako | Inagaki, Hirofumi | Hirata, Yukiyo | Takizawa, Hajime | Azuma, Arata | Yamamoto, Masayuki | Kawada, Tomoyuki | Kim, Min-Gu | Hong, Gyong Hwa | Lee, Kyoung Young | Ha, Eun Hee | Moon, Keun Ai | Park, Sunjoo | Kwon, Hyouk-Soo | Kim, Tae-Bum | Moon, Hee-Bom | Cho, You Sook | Kim, Jung-Hyun | Kim, Hyo-Jung | Park, So-Young | Seo, Bomi | Kim, Ji-Hye | Samivel, Ramachandran | Kim, Eun-Hee | Chung, Young-Jun | Mo, Ji-Hun | Soumya, M. S. | Inbaraj, G. | Chellaa, R. | Pawankar, Ruby | Choi, Wonsun | Park, Hae-Sim | Ye, Young Min | Kim, Ji Hye | Ban, Ga Young | Shin, Yoo-Seob | Braber, Saskia | Verheijden, Kim | Kraneveld, Aletta | Garssen, Johan | Folkerts, Gert | Willemsen, Linette | Eichhorn, Stephanie | Ferreira, Fatima | Pablos, Isabel | Kastner, Bianca | Schweidler, Bettina | Wildner, Sabrina | Briza, Peter | Park, Jung-Won | Arora, Naveen | Vieths, Stefan | Gadermaier, Gabriele | Park, Sung-Min | Lee, Won-Ku | Kim, Jeong-Min | Kim, Gun-Wook | Mun, Je-Ho | Kim, Hoon-Soo | Song, Margaret | Ko, Hyun-Chang | Kim, Moon-Bum | Kim, Byung Soo | Kim, Young Nam | Yune, Sehyo | Lee, Jin-Young | Kim, Jihye | Kim, Young Eun | Paeng, Jae-Won | Jang, Mi-Jin | Choi, Dong-Chull | Lee, Byung-Jae | Lee, Yongseok | Goh, Si Hui | Lee, Bee Wah | Soh, Jian Yi | Kang, Hyungoo | Kim, Hyunhee | Yum, Hye-Yung | Ye, Young Min | Park, Hae-Sim | Ban, Ga-Young | Kim, Ji Hye | Shin, Yoo Seob | Takizawa, Takumi | Tabata, Masahiko | Aizawa, Akira | Yagi, Hisako | Nishida, Yutaka | Arakawa, Hirokazu | Morikawa, Akihiro | Orosoo, Solongo | Braber, Saskia | Bol-Schoenmakers, Marianne | Akbari, Peyman | Jeurink, Prescilla V. | Jeurink, Prescilla V. | De Graaff, Priscilla | Smit, Joost J. | Van Esch, Betty C. A. M. | Garssen, Johan | Garssen, Johan | Fink-Gremmels, Johanna | Pieters, Raymond H. H. | Kim, Gun-Woo | Jo, Eun-Jung | Kim, Sujeong | Song, Woo-Jung | Chang, Yoon-Seok | Faruqi, Shoaib | Kim, Ju-Young | Kang, Mingyu | Kim, Min-Hye | Plevkova, Jana | Park, Heung Woo | Cho, Sang-Heon | Morice, Alyn | Lee, So-Hee | Kim, Sun-Sin | Lee, Seoung-Eun | Gemicioglu, Bilun | Misirligil, Zeynep | Cimrin, Arif Hikmet | Gunen, Hakan | Ozlu, Tevfik | Cilli, Aykut | Akyildiz, Levent | Bayram, Hasan | Uzaslan, Esra | Abadoglu, Oznur | Suerdem, Mecit | Kainuma, Keigo | Kim, Hyun-a | Kim, Ha-Su | Bae, Woo Yong | Jung, Jin-a | Kamenwa, Rose | Macharia, William | Said, Nusrat | Nerurkar, Vidya | Patel, Meenal | Bhatia, Simi | Choi, Inseon S. | Kim, Soo-Jeong | Won, Joo-Min | Park, Myeong-Soo | Nagao, Mizuho | Park, Dong Won | Sohn, Jang Won | Yhi, Ji Young | Moon, Ji-Yong | Kim, Sang-Heon | Kim, Tae Hyung | Shin, Dong Ho | Yoon, Ho Joo | Hyo, Yukiyoshi | Lee, Jaechun | Kim, Su Hee | Lee, Eunkyoung | Jung, Hahn Jin | Lim, Jaehyun | Hong, Seung-No | Han, Doo Hee | Rhee, Chae-Seo | Lee, Kun Song | Lee, Jaechun | Yang, Sun Young | Ahn, Mi Young | Lee, Jong Hoo | Golez, Jasmina | Tian, Hui-Qin | Cheng, Lei | Chen, Xin-Yuan | Moon, Ji-Yong | Kim, Sang-Heon | Kim, Tae Hyung | Yhi, Ji Young | Yoon, Ho Joo | Sohn, Jang Won | Shin, Dong Ho | Park, Dong Won | Cho, Won Im | Choi, Jong Sub | Suh, Dongin | Kang, Gyeong Hoon | Moon, Jin Soo | Ko, Jae Sung | Lee, Kyung Jae | Choi, Shin Jie | Luo, Wenting | Sun, Baoqing | Gao, Qi | Xiang, Li | Shen, Kunling | Jang, Yong Hyun | Bergmann, Karl-Christian | Sehlinger, Torsten | Bölke, Georg | Berger, Uwe | Zuberbier, Torsten | Kolodziejczyk, Joanna | Wojciechowska, Milena | Hnatyszyn-Dzikowska, Anna | Chojnacki, Micha | Bartuzi, Zbigniew | Masaki, Katsunori | Fukunaga, Koichi | Kamatani, Takashi | Ohtsuka, Kengo | Tanosaki, Takae | Matsusaka, Masako | Mochimaru, Takao | Kabata, Hiroki | Ueda, Soichiro | Suzuki, Yusuke | Kamei, Katsuhiko | Asano, Koichiro | Betsuyaku, Tomoko | Trafford, Karlee | Bulut, Ismet | Ozseker, Zeynep Ferhan | Horimukai, Kenta | Morita, Hideaki | Narita, Masami | Niizeki, Hironori | Matsumoto, Kenji | Ohya, Yukihiro | Saito, Hirohisa | Kabashima, Shigenori | Kondo, Mai | Inoue, Eisuke | Siebers, Robert | Wu, Francis F. S. | Siebers, Robert | Wu, Francis F. S. | Ting, Ming-Hui | Laio, Hung-En | Kuo, Tsung-Huai | Lee, Pei-Yuan | Maddox, Daniel Eugene | Ryu, Gwanghui | Kim, Hyo Yeol | Dhong, Hun-Jong | Hong, Sang Duk | Chung, Seung-Kyu | Higuchi, Osamu | Adachi, Yu-Ichi | Itazawa, Toshiko | Adachi, Yoko | Hamamichi, Miki | Nakabayashi, Motokazu | Ito, Yasunori | Wada, Takuya | Murakami, Gyoukei | Takao, Miki | Yamamoto, Junko | Jin, Hyun Jung | Yoon, Moon Gyeong | Ye, Young Min | Shin, Yoo-Seob | Kim, Seung-Hyun | Park, Hae-Sim | Min, Taek-Ki | Pyun, Bok-Yang | Lee, So-Yeon | Kim, Hyun Hee | Jang, Gwang-Cheon | Yu, Jinho | Suh, Dongin | Lee, Sooyoung | Park, Yong Mean | Kim, Jeong Hee | Yum, Hye-Yung | Kim, Kyung Won | Yang, Hyeon-Jong | Ahn, Kangmo | Kwon, Ji-Won | Sohn, Myung Hyun | Lee, Hae Ran | Kwon, Jung Hyun | Kim, Kyu-Earn | Hong, Soo-Jong | Cho, Su-Mi | Nahm, Dong-Ho | Kim, Myoung-Eun | Lee, Jin Hwa | Rhee, Chin Kook | Park, Hye Yun | Kim, Woo Jin | Park, Yong Bum | Yoo, Kwang-Ha | Kang, Heejeong | Yang, Hyeon-Jong | Min, Taek-Ki | Pyun, Bok-Yang | Suk, Lee Ju | Kim, Cheol Hong | Kwon, Jung Hyun | Lee, Sang Hyun | Seo, Wonhee | Kim, Kang-in | Park, Young Cheon | Yang, Hyeon-Jong | Min, Taek-Ki | Pyun, Bok-Yang | Kim, Sujeong | Jin, Sun | Lee, Jong-Myung | Jung, Hye-Jin | Park, Jung-Wha | Kim, Hyo-Jung | Kim, Tae-Bum | Cho, You Sook | Moon, Hee-Bom | Kwon, Hyouk-Soo | Park, So Young | Park, So-Young | Kim, Jung-Hyun | Seo, Bomi | Kim, Min-Gu | Kim, Youn Yee | Lee, Yena | Min, Taek-Ki | Yang, Hyeon-Jong | Pyun, Bok-Yang | Han, Suk Hee | Park, Suyeon | Lee, Jeongho | Hahn, Won-Ho | Jeon, Youhoon | Kim, Joo-Hee | Shin, Tae-Rim | Kim, Cheol-Hong | Hyun, In-Gyu | Choi, Jeong-Hee | Jang, Sun-Mi | Na, Hae-Jung | Song, Seung-Eon | Park, Hye-Kyung | Jo, Eun-Jung | Lee, Dong Hun | Lee, Jin-Young | Park, Yang | Oh, Jae-Won | Lee, Mi Hee | Hong, Soo-Jong | Hong, Soo-Jong | Lee, So-Yeon | Park, Joon Soo | Nahm, Dong-Ho | Yum, Hye-Yung | Yum, Hye-Yung | Choi, Kyu Young | Kim, Dong-Young | Palapinyo, Sirinoot | Klaewsongkram, Jettanong | Chen, Xing | Jin, Yuting | Hou, Xiaoming | Liu, Fengqin | Guo, Chunyan | Wang, Yulin | Okafuji, Ikuo | Tanaka, Yuya | Narabayashi, Shegeyuki | Tsuruta, Satoru | Jang, Yong Hyun | Ahn, Jun-Hong | Lee, Dong-Won | Chung, Jin Hong | Jin, Hyun Jung | Sohn, Min-Su | Park, Young a | Jeong, Kyunguk | Kim, Yoon Hee | Sol, In Suk | Yoon, Seo Hee | Kim, Kyung Won | Sohn, Myung Hyun | Kim, Kyu-Earn | Lee, Sooyoung | Kim, Ho | Kim, Ja Yeun | Lee, So-Yeon | Min, Taek-Ki | Song, Tae-Won | Ahn, Kangmo | Kim, Jihyun | Jang, Gwang-Cheon | Yang, Hyeon-Jong | Pyun, Bok-Yang | Kwon, Ji-Won | Sohn, Myung Hyun | Kim, Kyu-Earn | Yu, Jinho | Hong, Soo-Jong | Kwon, Jung-Hyun | Kim, Sung-Won | Lee, Sooyoung | Kim, Woo Kyung | Kim, Hyung Young | Kim, Hye-Young | Jeon, Youhoon | Lim, Chang Hoon | Jeong, Yeongsang | Kim, Su Jung | Chang, Hun Soo | Heo, Jeong-Seok | Bae, Da-Jeong | Lee, Jong-Uk | Kim, Ji-Na | Min, Chang-Gi | Song, Hyun Ji | Park, Jong-Sook | Kim, Soo Hyun | Park, Choon-Sik | Liu, Jing-Nan | Choi, Youngwoo | Shin, Yoo Seob | Park, Hae-Sim | Rezaei, Nima | Mahneh, Sedigheh Bahrami | Rezaei, Arezou | Sadr, Maryam | Movahedi, Masoud | Gang, Jun Seak | Park, Joon Soo | Kim, Seung Soo | Bang, Hyun Ho | Park, Kyeong Bae | Kim, Hye Sun | Kim, Tae Ho | Hwangbo, Young | Lee, Hyun Jung | Yoo, Gyeong Hee | Kim, Young Chang | Sato, Sakura | Yanagida, Noriyuki | Ebisawa, Motohiro | Palikhe, Sailesh | Park, Hae-Sim | Kim, Seung-Hyun | Kim, Ri-Yeon | Yang, Eun-Mi | Lee, Li Yuan Gabriella Nadine | Aw, Marion | Aw, Marion | Lee, Bee Wah | Lee, Bee Wah | Loo, Evelyn Xiu Ling | Chan, Yiong Huak | Shek, Lynette | Shek, Lynette | Kuo, I-Chun | Kuo, I-Chun | Quah, Phaik Ling | Quah, Phaik Ling | Llanora, Genevieve | Irvin, Gerez | Jung, Joo Hyun | Kang, Il Gyu | Kim, Seon Tae | Park, Hyoungmin | Kim, Seon Tae | Jung, Joo Hyun | Kang, Il Gyu | Park, Hyoungmin | Ko, Kwang-Pil | Lee, Jungsoo | Chu, Howard | Lee, Hemin | Shin, Jung U. | Park, Chang Ook | Lee, Kwang Hoon | Lee, Kwang Hoon | Kang, Hong Kyu | Lee, Dong Chang | Kim, Geun Jeon | Hwang, Jae Hyung | Ha, Jin Bu | Jeong, Su Hee | Kim, Ho | Hwang, Shinha | Lee, Whahee | Bazarsad, Enkhbayar | Narantsetseg, Logii | Sonomjamts, Munkhbayarlakh | Jang, Gwang-Cheon | Lee, Hyun-Hee | Lee, Chang-Jong | Lim, Huynsun | Soh, Ji-Eun | Song, Dae-Jin | Kwon, Ji-Won | Kim, Hyung Young | Seo, Ju-Hee | Kim, Byoung-Ju | Kim, Hyo-Bin | Lee, So-Yeon | Jang, Gwang-Cheon | Kim, Woo Kyung | Jung, Young-Ho | Hong, Soo-Jong | Shim, Jung Yeon | Bazarsad, Enkhbayar | Narantsetseg, Logii | Sonomjamts, Munkhbayarlakh | Pv, Prabhakarrao | Nadendla, Ranjitha | Fang, Juan | Zhao, Jing | Song, Dae-Jin | Seo, Sungchul | Yoo, Young | Kim, Yu-Ri | Choung, Ji Tae | Lee, Jee Hoo | Berings, Margot | De Ruyck, Natalie | Bachert, Claus | Gevaert, Philippe | Holtappels, Gabriële | Lee, Pureun-Haneul | Kim, Byeong-Gon | Park, Choon-Sik | Leikauf, George D. | Jang, An-Soo | Kimc, Byeong-Gon | Lee, Pureun-Haneul | Park, Choon-Sik | Jang, An-Soo | Park, Yang | Sohn, Min-Su | Jin, Hyun Jung | Lee, Dong-Won | Ahn, Jun-Hong | Chung, Jin Hong | Kim, Sae-in | Park, Han-Ki | Kim, Do-Yeon | Rho, Mina | Choi, Jun-Pyo | Kim, Yoon-Keun | Kamchaisatian, Wasu | Hiranras, Thitikul | Wongpun, Surinda | Chiraphorn, Phornthip | Tantachun, Anupan | Wongrassamee, Wannipa | Vatanasurkitt, Planee | Somboonkul, Naratip | Juthacharoenwong, Nattipat | Techapaitoon, Surangkana | Tuchinda, Montri | An, Sejin | Lee, Jae Ho | Shin, Ji-Hyeon | Kim, Soo Whan | Kim, Si Won | Kang, Jun Myung | Kim, Boo-Young | Kim, Byung-Guk | Kwon, Ji-Won | Kim, Woo Kyung | Kim, Hyung Young | Kim, Hyo-Bin | Seo, Ju-Hee | Lee, So-Yeon | Jang, Gwang-Cheon | Jung, Young-Ho | Hong, Soo-Jong | Kim, Byoung-Ju | Song, Dae-Jin | Shim, Jung Yeon | Lee, Jung-Won | Kim, Kyung Ho | Yoo, Young | Yoon, Won Suck | Seo, Sungchul | Kang, In Soon | Choi, Jae Won | Lim, Hye-Young | Choung, Ji Tae | Buela, Michelle | Nishimura, Koji | Park, Sang Chul | Chung, Hyo Jin | Kim, Chang-Hoon | Kang, Ju Wan | Hong, Seong-Chul | Lee, Keun-Hwa | Lee, Jaechun | Lee, Hye-Sook | Kim, Jeong Hong | Logii, Narantsetseg | Nyamdavaa, N. | Enkhbayar, B. | Oyuntsatsral, B. | Munkhbayarlakh, S. | Bazarsad, Enkhbayar | Sonomjamts, Munkhbayarlakh | Omarjee, Bashir | Li, Shuo | Hayashi, Miyuki | Pawankar, Ruby | Yamanishi, Shingo | Igarashi, Toru | Itoh, Yasuhiko | Gantulga, B. | Enkhbayar, B. | Munkhbayarlakh, S. | Narantsetseg, L. | Batsaikhan, Oyuntsatsral | Chen, Pei-Chi | Wang, Jiu-Yao | Leung, Nicki Y. H. | Wai, Christine Yee Yan | Leung, Patrick S. C. | Chu, Ka Hou | Doh, Eun Jin | Lee, Dong Hun | Choi, Mira | Yoon, Hyun-Sun | Kim, Kyu Han | Lim, Ji Soo | Baek, Ji Hyeon | Han, Man Yong | Lee, Seung Jin | Jeon, Youhoon | Lee, Kyung Suk | Jung, Young-Ho | Jee, Hye Mi | Shin, Youn Ho | Jiang, Yi | Liu, Miao | Naing, Chaw Su | Tan, Tze Chin | Chong, Yong Yeow | Kim, Young-Ho | Lee, Eun | Yang, Song-I | Cho, Hyun-Ju | Kim, Hyung Young | Kwon, Ji-Won | Jung, Young-Ho | Kim, Byoung-Ju | Seo, Ju-Hee | Kwon, Ho-Jang | Kim, Hyo-Bin | Lee, So-Yeon | Hong, Soo-Jong | Kim, Soo Hyun | Joseph, Jacqueline Elizabeth | Soumya, M. S. | Pawankar, Ruby | Kumar, Harshitha | Yang, Sohyoung | Woo, Sung-Il | Rezaei, Nima | Kose, Sukran | Serin, Basak Gol | Yalcin, Arzu Didem | Senger, Süheyla Serin | Erden, Mehmet | Serin, Ertan | Leung, Ting Fan | Leung, Agnes Sze-Yin | Kumar, Harshitha | Soumya, M. S. | Joseph, Jacqueline Elizabeth | Pawankar, Ruby | Chung, Eun Hee | Kim, Eunji | Yoo, Young | Yoo, Young | Choung, Ji Tae | Choung, Ji Tae | Seo, Sungchul | Seo, Sungchul | Kang, In Soon | Lee, Jue Seong | Hwang, Ji Hyen | Lee, Sang Min | Jung, Joo Hyun | Choi, Seung Joon | Joe, Eugene | Hwang, Hyunjung | Kang, Shin Myung | Kim, Yu Jin | Kyung, Sun Young | Park, Jeong-Woong | Jeong, Sung Hwan | Lee, Sang Pyo | Gaisina, Alina | Shilovskiy, Igor | Nikonova, Aleksandra | Kamyshnikov, Oleg | Khaitov, Musa | Mitin, Alexander | Viktoriya, Komogorova | Litvina, Marina | Sharova, Nina | Faiah, M. J. | Ismail, Intan H. | Miles, E. A. | Jamli, Faizah Mohamed | Choi, Jun-Pyo | Choi, Han-Byul | Kim, Yoon-Keun | Choi, Hyeon-Il | Yoon, Da-Il | Kang, Mingyu | Kim, Mi Yeoung | Kim, Sujeong | Jo, Eun-Jung | Lee, Seoung-Eun | Song, Woo-Jung | Lee, Sang Min | Park, Chansun | Chang, Yoon-Seok | Lee, Jaechun | Jee, Young-Koo | Choi, Inseon S. | Min, Kyung-up | Cho, Sang-Heon | Cho, Sang-Heon | Laskin, Anton | Kamyshnikov, Oleg | Babakhin, Alexander | Berzhets, Valentina | Khaitov, Musa | Lee, Jae Ho | An, Sejin | Chang, Yoon-Seok | Min, Kyung-up | Cho, Sang-Heon | Kim, Sae-Hoon | Kwon, Yong Eun | Jee, Young-Koo | Kim, Tae-Bum | Moon, Hee-Bom | Park, Hye-Kyung | Kang, Sung-Yoon | Choi, Jun-Pyo | Park, Han-Ki | Lee, Ji-Hyun | Kim, Yoon-Keun | Kim, Sang-Yoon | Hwang, Hyunjung | Joe, Eugene | Lee, Sang Min | Choi, Seung Joon | Jung, Joo Hyun | Seon, Yong Han | Kang, Shin Myung | Kim, Yu Jin | Kyung, Sun Young | Park, Jeong-Woong | Jeong, Sung Hwan | Lee, Sang Pyo | Khramykhoverchenko, Natalya | Sultana, Asma | Halwani, Rabih | Bahammam, Ahmed | Al Muhsen, Saleh | Kim, Sun Kyung | Nam, Kwang Il | Yang, Hyung Chae | Kim, Jeong-Eun | Lee, Ju Suk | Lee, Ji Hyun | Kang, Kyung Woo | Kim, Je-Kyung | Hahn, Youn-Soo | Jung, Jae-Yub | Baba, Yosuke | Yamazaki, Sususmu | Inage, Eisuke | Mori, Mari | Ohtsuka, Yoshikazu | Kantake, Masato | Shimizu, Toshiaki | Honjoh, Asuka | Yokokura, Tomoaki | Elhassan, Shaza Ali Mohammed | Beck, Caroline | Adeli, Mehdi | Baek, Heysung | Lee, Seung Jin | Baek, Ji Hyeon | Yoon, Jungwon | Choi, Sun Hee | Jung, Young-Ho | Shin, Youn Ho | Han, Man Yong | Na, Min Sun | Compalati, Enrico | Marogna, Maurizio | Huang, Huimin | Sun, Baoqing | Bai, Mingyu | Huo, Yiting | Zheng, Peiyan | Wei, Nili | Luo, Wenting | Andiappan, Anand | Minisini, Rosalba | Rötzschke, Olaf | Boggio, Elena | Gigliotti, Luca | Clemente, Nausicaa | Chiocchetti, Annalisa | Dianzani, Umberto | Pirisi, Mario | Villa, Elisa | Yamaide, Fumiya | Yonekura, Syuji | Shimojo, Naoki | Inoue, Yuzaburo | Okamoto, Yoshitaka | Setyoningrum, Retno Asih | Setiawati, Landia | Sumei, Sri | Iskandar, Deddy | Kompiyang, Indriyani Sang Ayu | Oguma, Tsuyoshi | Tanaka, Jun | Tomomatsu, Katsuyoshi | Asano, Koichiro | Uno, Keisuke | Matsuwaki, Yoshinori | Omura, Kazuhiro | Hayashi, Eika | Tatsumi, Norifumi | Kita, Hirohito | Otori, Nobuyoshi | Kojima, Hiromi | Khorasgani, Mohammadreza Fatemi | Lew, Dukhee/Betty | Lemessurier, Kim/S. | Moore, Joseph/a | Park, Jeoung-Eun | Yi, Ae-Kyung | Song, Chi/Young | Malik, Kafait/U | Kim, Ja Kyoung | Yang, Hyeon-Jong | Kim, Bong-Seong | Shin, Youn Ho | Lee, So-Yeon | Park, Geunhwa | Kim, Woo Kyung | Kim, Hyo-Bin | Baek, Heysung | Lim, Dae Hyun | Lim, Dae Hyun | Kim, Jin Tack | Suh, Dongin | Nano, Aimee Lou Manalo | Sun, Baoqing | Luo, Wenting | Nacaroglu, Hikmet Tekin | Erdem, Semiha Bahceci | Sumer, Ozlem | Karaman, Sait | Karkiner, Canan Sule Unsal | Asilsoy, Suna | Gunay, Ilker | Can, Demet | Kiers, Danielle | Wang, Jiu-Yao | Yin, Hsu Han | Kaplan, Allen | Joseph, Kusumam | Tholanikunnel, Baby G. | Dudek, Radim | Bilgin, Gulden | Surer, Hatice | Kilinc, Aytun Sadan | Yucel, Dogan | Lee, Ji Young | Kim, Jihyun | Yang, Hea-Kyoung | Kim, Minji | Lee, Sang-Il | Ahn, Kangmo | Moon, Sung Do | Kim, Byung-Keun | Cho, Sang-Heon | Min, Kyung-up | Chang, Yoon-Seok | Park, Heung Woo | Kang, Hye-Ryun | Song, Woo-Jung | Kang, Min-Koo | Kim, Ju-Young | Sohn, Kyonghee | Won, Ha Kyung | Lee, Seoung-Eun | Kim, Kyung-Mook | Bachert, Claus | Hsieh, Miao-Hsi | Wang, Jiu-Yao | Smith, Helen | Brown, Clare | Jones, Christina | Davies, Mark | Yoon, Won Suck | Lee, Hemin | Chu, Howard | Lee, Jungsoo | Shin, Jung U. | Park, Chang Ook | Lee, Kwang Hoon | Lee, Kwang Hoon | Kim, Seo Hyeong | Kim, Seo Hyeong | Noh, Ji Yeon | Kim, Ji Hye | Kim, Ji Hye | Yoon, Won Suck | L’huillier, Jean-Pierre | Autegarden, Jean-Eric | Bertrand, Catherine | Tardy, Dominique | Ismail, Intan Hakimah | Tang, Mimi | Licciardi, Paul | Oppedisano, Frances | Boyle, Robert | Robins-Browne, Roy | Yagi, Hisako | Koyama, Harumi | Nishida, Yutaka | Takizawa, Takumi | Arakawa, Hirokazu | Kang, Hong Kyu | Lee, Hemin | Lee, Jungsoo | Shin, Jung U. | Lee, Kwang Hoon | Lee, Kwang Hoon | Chu, Howard | Park, Chang Ook | Yoon, Na Young | Lee, Hyeyoung | Seo, Seong Jun | Choi, Eunhee | Wang, Hye-Young | Jung, Minyoung | Choi, Eung Ho | Kim, Dong Hye | Kim, Joo-Hee | Jang, Young-Sook | Choi, Jeong-Hee | Park, Sunghoon | Hwang, Young Il | Jang, Seung Hun | Jung, Ki-Suck | Kang, Mi-Jin | Suh, Dongin | Lee, Eun | Choi, Kil Yong | Jung, Young-Ho | Yang, Song-I | Kim, Bong-Soo | Kim, Ha-Jung | Koh, Juneyoung | Kim, Hyun-Jin | Ahn, Kangmo | Shin, Youn Ho | Cho, Hyun-Ju | Kim, Byoung-Ju | Kim, Young-Ho | Jung, Yean | Mamura, Mizuko | Yoon, Jeong-Hwan | Nakae, Susumu | Lee, Inkyu | Matsumoto, Isao | Sumida, Takayuki | Han, Jin Soo | Sudo, Katsuko | Ju, Ji Hyeon | Yap, Gaik Chin | Liu, Wen Tso | Oh, Seungdae | Hong, Pei Ying | Huang, Chiung Hui | Aw, Marion | Shek, Lynette | Lee, Bee Wah | Byun, Young Seok | Kim, Sung Wan | Koh, Tae Kyung | Jo, Joong-Saeng | Lee, Kun Hee | Kwon, Chul | Dong, Sung-Hwa | Kim, Myung Shin | Park, Chansun | Cho, Han Seok | Kim, Min-Ju | Kim, Min Ji | Park, Young Ok | Lee, Hye Yeong | Kim, Hee Seong | Lee, Eun | Cho, Hyun-Ju | Yu, Jinho | Hong, Soo-Jong | Hwang, Keum Hee | Kim, Jung-Hyun | Cho, You Sook | Kim, Sae-Hoon | Kwon, Hyouk-Soo | Yoo, Mira | Kim, Hyo-Jung | Park, So-Young | Shin, Bomi | Park, So Young | Seo, Bomi | Kim, Min-Gu | Moon, Hee-Bom | Park, Jin-Ah | Kim, Tae-Bum | Lee, Jaemoon | Jeong, Jin Hyeok | Kang, Tae Wook | Yoo, Han Seok | Cho, Yong Hee | Cho, Seok Hyun | Kim, Kyung Rae | Lee, Jue Seong | Kee, Sun-Ho | Kim, Sewon | Yoo, Young | Na, Heung Sik | Back, Seung Keun | Lee, Seung Jin | Seo, Bo Seon | Baek, Ji Hyeon | Lee, Kyung Suk | Jung, Young-Ho | Jee, Hye Mi | Shin, Youn Ho | Han, Man Yong | Kim, Mi-Ae | Nam, Young-Hee | Jeon, Dong Sub | Lee, Soo-Keol | Park, Jisun | Moon, Seung Hyun | Lin, Rong Jun | Guan, Ren Zheng | Park, Gyeong Yul | Yoon, Hyun-Sun | Choi, Woo-Hyeok | Baek, Heysung | Park, Jin-Sung | Kwon, Eunmi | Callaway, Zac | Kim, Chang-Keun | Fujisawa, Takao | Zhang, Qingling | Qiu, Rihuang | Li, Naijian | Yang, Zhaowei | Li, Jing | Chung, Kian Fan | Zhong, Nanshan | Hon, Kam Lun E. | Tsang, Yin Ching K. | Leung, Ting Fan | Jang, Yoon Young | Chung, Hai Lee | Lee, Seung Gook | Na, Ji Hyun | Lee, Jong Hoon | Nam, Young-Hee | Jeon, Dong Sub | Lee, Soo-Keol | Yamamoto, Mikita | Sato, Sakura | Yanagida, Noriyuki | Ogawa, Ayako | Ogura, Kanako | Takahashi, Kyohei | Nagakura, Kenichi | Emura, Shigehito | Asaumi, Tomoyuki | Iikura, Katsuhito | Ebisawa, Motohiro | Okada, Yu | Luo, Jiaying | Lan, Xiao | Sun, Baoqing | Chen, Zhao | Sun, Guiyuan | Li, Shimin | Hu, Jiaqing | Choi, Woo-Hyeok | Baek, Heysung | Nam, Young-Hee | Jeon, Dong Sub | Nam, Hee-Joo | Noh, Yeo Myeong | Kim, Sang Hee Kim | Park, Ye Suel | Lee, Soo-Keol | Choi, Yean Jung | Lee, Si Hyeon | Kim, Young-Ho | Kang, Mi-Jin | Cho, Hyun-Ju | Lee, Eun | Yang, Song-I | Shin, Youn Ho | Ahn, Kangmo | Kim, Kyung Won | Kim, Yoon Hee | Lee, So-Yeon | Chang, Hyoung Yoon | Choi, In Ae | Lee, Kyung-Sook | Shin, Yee-Jin | Kim, Yoon Hee | Kim, Min Jung | Sol, In Suk | Yoon, Seo Hee | a Park, Young | Kim, Kyung Won | Sohn, Myung Hyun | Kim, Kyu-Earn | Lee, Yong Ju | Sol, In Suk | Kim, Kyu-Earn | Kim, Yoon Hee | Kim, Min Jung | Yoon, Seo Hee | Lee, Yong Ju | Kim, Kyung Won | a Park, Young | Sohn, Myung Hyun | Park, Sung Joo | Kwon, Ji-Won | Kim, Woo Kyung | Kim, Hyung Young | Kim, Hyo-Bin | Seo, Ju-Hee | Lee, So-Yeon | Jang, Gwang-Cheon | Jung, Young-Ho | Hong, Soo-Jong | Kim, Byoung-Ju | Song, Dae-Jin | Yang, Yun Seok | Shim, Jung Yeon | Jang, Yoon Young | Chung, Hai Lee | Kim, Ji Hye | Lee, Hyun Seok | Lee, Chang Ho | Cho, Changbum | Lim, Yun-Kyu | Kim, Kyu Rang | Kim, Mijin | Kim, Baek-Jo | Kim, Young-Min | Han, Youngshin | Kim, Jihyun | Cheong, Hae-Kwan | Jeon, Byoung-Hak | Ahn, Kangmo | Ming, Chuang/Yao | Wang, Jiu-Yao | Ling, Ye/Yi | Huang, Huimin | Sun, Baoqing | Chen, Yun | Zheng, Peiyan | Wei, Nili | Luo, Wenting | Lee, Do Hyeong | Choi, Gil-Soon | Kim, Hee-Kyoo | Park, Han Su | Park, So-Young | Kim, Hyo-Jung | Seo, Bomi | Kim, Jung-Hyun | Kim, Min-Gu | Kwon, Hyouk-Soo | Cho, You Sook | Moon, Hee-Bom | Kim, Tae-Bum | Lee, Yoon Su | Shin, Eun-Soon | Tanaka, Akio | Morioke, Satoshi | Ohya, Yukihiro | Shimojo, Naoki | Akasawa, Akira | Hide, Michihiro | Shizukawa, Hiroko | Watanabe, Naoto | Shin, Meeyong | Jang, Myeong Sun | Nam, Young-Hee | Noh, Yeo Myeong | Jeon, Dong Sub | Nam, Hee-Joo | Kim, Sang Hee Kim | Park, Ye Suel | Lee, Soo-Keol | Jung, Ji-in | Kim, Ha-Su | Kim, Hyun-a | Jung, Jin-a | Goh, Anne | Rao, Rajeshwar | Nandanan, Bindu | Van Elburg, Ruurd | Chien, Chua Mei | Jo, Juandy | Garssen, Johan | Garssen, Johan | Knippels, Leon | Sandalova, Elena | Chiang, Wen Chin | Nam, Young-Hee | Juong, Ji Young | Kim, Soo Jin | Kim, Eun Young | Lee, Su Mi | Son, Young Ki | Nam, Hee-Joo | Kim, Ki-Ho | Lee, Soo-Keol | Park, Da-Eun | Kang, Hye-Ryun | Park, Heung Woo | Lee, Hyun Seung | Chang, Yoon-Seok | Park, Jung-Won | Cho, Sang-Heon | Min, Kyung-up | Song, Woo-Jung | Lim, Hyunwook | Seo, Sungchul | Choung, Ji Tae | Yoo, Young | Park, Jun-Sik | Kim, Byung Kwan | Won, Ha Kyeong | Kang, Hye-Ryun | Kim, Byung-Keun | Moon, Sung Do | Kim, Ju-Young | Lee, So-Hee | Song, Woo-Jung | Park, Heung Woo | Kang, Min-Koo | Kim, Sun-Sin | Cho, Sang-Heon | Min, Kyung-up | Chang, Yoon-Seok | Sohn, Kyoung Hee | Kim, Kyung-Mook | Kim, Ki-Woong | Jang, Hak Chul | Nam, Young-Hee | Jeon, Dong Sub | Nam, Hee-Joo | Noh, Yeo Myeong | Kim, Sang Hee Kim | Park, Ye Suel | Lee, Soo-Keol | Leung, Ting Fan | Tang, Man Fung | Sy, Hing Yee | Chan, Wa Cheong | Tam, Wilson Wai San | Chung, Seung Kyu | Kim, Sujin | Hong, Sang Duk | Kim, Hyo Yeol Kim Hyo Yeol | Dhong, Hun-Jong | Jeong, Jong in | Nam, Young-Hee | Jeon, Dong Sub | Lee, Soo-Keol | Lee, Ji Won | Kang, Mingyu | Kim, Soon-Hee | Bae, Boram | Kim, Sujeong | Kang, Hye-Ryun | Chang, Yoon-Seok | Song, Woo-Jung | Park, Da-Eun | Lee, Hyun Seung | Park, Heung Woo | Park, Han-Ki | Park, Jung-Won | Nam, Young-Hee | Jeon, Dong Sub | Nam, Hee-Joo | Noh, Yeo Myeong | Kim, Sang Hee Kim | Park, Ye Suel | Lee, Soo-Keol | Hou, Yung-I | Wang, Jiu-Yao | Kim, Ja Hyeong | Hee, Seol Jae | Ha, Eun-Hee | Park, Hyesook | Ha, Mina | Hong, Yun-Chul | Kim, Yangho | Chang, Namsoo | Soma, Yuta | Watanabe, So | Pawankar, Ruby | Suzaki, Harumi | Kobayashi, Hitome | Nam, Young-Hee | Park, Chansun | Lee, Soo-Keol | Lee, Jongrok | Roh, Jooyoung | Ryu, Haryeong | Kim, Cheol-Woo | Cho, Jae Hwa | Eom, Mi Ra | Kang, Ji Young | Lee, Hye Gyeung | Choi, Hae Young | Lee, Hye Jin | Woo, Ju Yun | Byun, Ji Yeon | Choi, You Won | Kim, Ja Hyeong | Ha, Eun-Hee | Park, Hyesook | Ha, Mina | Hong, Yun-Chul | Kim, Yangho | Chang, Namsoo | Kwon, Jae-Woo | Chang, Hun Soo | Heo, Jeong-Seok | Lee, Jong-Uk | Park, Jong-Sook | Kim, Eusom | Kim, Soo Hyun | Park, Choon-Sik | Choi, Hae Young | Byun, Ji Yeon | Woo, Ju Yun | Choi, You Won | Jin, Hyun-Ju | Son, Jin-Hwa | Kim, Jeong-Min | Kim, Gun-Wook | Mun, Je-Ho | Song, Margaret | Ko, Hyun-Chang | Kim, Moon-Bum | Kim, Hoon-Soo | Kim, Byung Soo | Van Nunen, Sheryl | Van Nguyen, Dinh | Elias, Anthony | Lauer, Susannah Olivia | Lee, Seung-Chul | Lee, Ho-June | Bae, Jung Min | Ono, Emi | Dong, Sung-Hwa | Koh, Tae Kyung | Byun, Young Seok | Kim, Sung Wan | Jo, Joong-Saeng | Kwon, Chul | Lee, Kun Hee | Liu, Li-Fan | Lee, Sunghee | Chen, Wei-Leng | Wang, Jiu-Yao | Bae, Youin | Park, Gyeong-Hun | Kim, Suk Yeon | Lee, Hyun Seung | Song, Woo-Jung | Kang, Mingyu | Park, Han-Ki | Park, Da-Eun | Kang, Hye-Ryun | Park, Heung Woo | Chang, Yoon-Seok | Kim, Hye-Young | Min, Kyung-up | Cho, Sang-Heon | Lee, Ji-Won | Bae, Boram | Park, Jung-Won | Suzuki, Yasuhiro | Bulut, Ismet | Ozseker, Zeynep Ferhan | Ismail, Intan Hakimah | Boyle, Robert | Licciardi, Paul | Oppedisano, Frances | Robins-Browne, Roy | Tang, Mimi | Lee, Ji Won | Lee, Hyun Seung | Kang, Mingyu | Park, Da-Eun | Park, Han-Ki | Kim, Soon-Hee | Song, Woo-Jung | Kang, Hye-Ryun | Park, Heung Woo | Chang, Yoon-Seok | Park, Chang-Han | Chang, Suk-Il | Song, Sook-Hee | Min, Kyung-up | Cho, Sang-Heon | Bae, Boram | Shieh, Grace | Kim, Min Jung | Hong, Jung Yeon | Yoon, Seo Hee | Shim, Doo Hee | Sol, In Suk | Kim, Yoon Hee | Kim, Mi Na | Lee, Kyung Eun | Kim, Kyung Won | Sohn, Myung Hyun | Kim, Kyu-Earn | Lee, Jae Myun | Chng, Hiok Hee | Kim, Dong Chan | Yang, Song-I | Lee, Hae Ran | Seo, An Deok | Lee, So Yeon | Artesani, Maria Cristina | Francalanci, Paola | Dahdah, Lamia | Schreiner, Thomas | Fiocchi, Alessandro | Chakraborty, Kaushik | Won, Ha Kyeong | Kim, Ju-Young | Jo, Eun-Jung | Sohn, Kyoung Hee | Kim, Kyung-Mook | Park, Heung Woo | Chang, Yoon-Seok | Cho, Sang-Heon | Song, Woo-Jung | Kim, Byung-Keun | Yonekura, Syuji | Okamoto, Yoshitaka | Hur, Gyu Young | Ye, Young Min | Kim, Joo-Hee | Jung, Ki-Suck | Kim, Junga | Shim, Jae Jeong | Park, Hae-Sim | Sekimoto, Kazuhiro | Sugai, Kazuko | Tsuchimoto, Keiji | Uehara, Hiromi | Ikeda, Masanori | Chung, Euncho | Park, Kang Seo | Choi, Yean Jung | Park, Jeewon | Hong, Soo-Jong | Lee, So Yeon | Jacquet, Alain | Buaklin, Arun | Malainual, Nat | Roopashree, S. | Kim, Kyu Rang | Kim, Mijin | Cho, Changbum | Kim, Baek-Jo | Oh, Jae-Won | Han, Mae Ja | Cho, Hyun-Ju | Shin, Youn Ho | Lee, Eun | Kim, Young-Ho | Lee, Darae | Kang, Mi-Jin | Yang, Song-I | Ahn, Kangmo | Kim, Kyung Won | Kim, Yoon Hee | Won, Hye-Sung | Kim, Soo Hyun | Choi, Suk-Joo | Kim, Young Han | Jun, Jong Kwan | Kim, Eun-Jin | Lee, Jeom Gyu | Lee, So-Yeon | Hong, Soo-Jong | Suh, Dongin | Amagai, Yosuke | Tanaka, Akane | Matsuda, Hiroshi | Mösges, Ralph | Dieterich, Pauline | Astvatsatourov, Anatoli | Hüser, Christoph | Singh, Jaswinder | Shah-Hosseini, Kija | Allekotte, Silke | Compalati, Enrico | Sohn, Kyoung Hee | Song, Woo-Jung | Kim, Byung-Keun | Kim, Ju-Young | Yang, Min Suk | Lee, So-Hee | Kim, Sae-Hoon | Kang, Hye-Ryun | Park, Heung Woo | Kim, Sun-Sin | Min, Kyung-up | Cho, Sang-Heon | Chang, Yoon-Seok | Chang, Woo-Sung | Do, Ji-Hye | Kim, Yeon-Seop | Yoon, Dankyu | Lim, Hye-Sun | Lee, Jeom-Kyu | Kim, Eun-Jin | Thong, Bernard | Cheng, Yew Kuang | Hou, Jinfeng | Leong, Khai Pang | Tan, Justina | Chia, Faith | Chan, Grace | Tan, Sze-Chin | Tan, Teck Choon | Tang, Chwee Ying | Chng, Hiok Hee | Park, Chan-Sun | Kim, Mi Yeoung | Kim, Eun-Young | Shin, Jae-Gook | Choi, Jae-Hyeog | Park, Saegwang | Kim, Yeonye | Lim, Kyung-Hwan | Jung, Jae Woo | Kang, Mingyu | Kim, Ju-Young | Kim, Ju-Young | Kim, Hyun Jeong | Woo, Yeon-Ju | Jung, Soo-Youn | Kang, Hye-Ryun | Kang, Hye-Ryun | Porée, Thierry | Boukhettala, Nabile | Furon, Emeline | Bullimore, Alan David | Heath, Matthew | Hewings, Simon | Skinner, Murray | Kurowski, Marcin | Krysztofiak, Hubert | Wardzynska, Aleksandra | Jarzebska, Marzanna | Jurczyk, Janusz | Kowalski, Marek L. | Kim, So Ri | Lee, Yong Chul | Kim, Dong Im | Rhee, Yang Keun | Lee, Heung Bum | Park, Seoung Ju | Choe, Yeong Hun Choe | Park, Seung Yong | Kim, Joo-Hee | Park, Sunghoon | Hwang, Young Il | Jang, Seung Hun | Jung, Ki-Suck | Min, Jiang | Guang-Min, Nong | Nag, Nalin | Indawati, Wahyuni | Bullimore, Alan David | Heath, Matthew | Skinner, Murray | Seo, Seong Jun | Oh, Won Jong | Bullimore, Alan David | Skinner, Murray | Heath, Matthew | Bell, Andrew | Hasanzadeh, Hournaz | Sadeghzade, Salman | Rezaei, Nima | Zarebidoki, Alireza | Cho, Kyu-Sup | Oh, Moo-Young | Kim, Sung-Woo | Koizumi, Munemitsu | Kuzume, Kazuyo | Park, Kui Young | Oh, Won Jong | Babaie, Delara | Nabavi, Mohammad | Zandieh, Fariborz | Moini, Mehrdad Amir | Chavoshzadeh, Zahra | Seifi, Hamideh | Sahragard, Mitra | Mesdaghi, Mehrnaz | Bemanian, Mohammad Hassan | Choi, Sun Young | No, Yeon a | Kiedik, Dorota | Muszynska, Agnieszka | Pirogowicz, Iwona | Fal, Andrzej M. | Motomura, Chikako | Wakatsuki, Masatoshi | Akamine, Yuko | Iwata, Mihoko | Matsuzaki, Hiroshi | Taba, Naohiko | Murakami, Yoko | Odajima, Hiroshi | Ghrahani, Reni | Takaoka, Yuri | Lee, Jong-Uk | Heo, Jeong-Seok | Bae, Da-Jeong | Song, Hyun Ji | Park, Choon-Sik | Park, Jong-Sook | Cho, Jae Hoon | Choi, Ji Ho | Febriana, Fiska | Ghrahani, Reni | Sapartini, Gartika | Setiabudiawan, Budi | Nam, Young-Hee | Kim, Mi Yeoung | Choi, Gil-Soon | Park, Chan-Sun | Huang, Chiung-Hui | Soh, Jian Yi | Shek, Lynette | Shek, Lynette | Delsing, Dianne J. | Lee, Bee Wah | Lee, Bee Wah | Goh, Si Hui | Chiang, Wen Chin | Loh, Wenyin | Yang, Hea-Kyoung | Lee, Ji Young | Kim, Minji | Ahn, Kangmo | Kim, Jihyun | Kim, Young-Min | Kim, Hye-Young | Park, Yong Mean | Kim, Woo Kyung | Lee, So-Yeon | Jeong, Jongin | Hong, Sang Duk | Chung, Seung Kyu | Dhong, Hun-Jong | Kim, Hyo Yeol | Kim, Sujin | Bak, Hana | Son, Hye-Rim | Lee, Si-Eun | Kim, Kwang-Jin | Lim, Young-Wook | Kim, Ho-Hyun | Lee, Yong-Won | Han, Man Yong | Jung, Young-Ho | Jee, Hye Mi | Lee, Seung Jin | Lee, Kyung Suk | Kim, Mi-Ae | Lee, Jaechun | Lee, Eunkyoung | Golez, Jasmina | Bae, Da-Jeong | Min, Chang-Gi | Lee, Jong-Uk | Park, Jong-Sook | Chang, Hun Soo | Park, Choon-Sik | Jang, An-Soo | Kim, Ha-Jung | Kim, Young-Joon | Jung, Bok Kyoung | Lee, Seung-Hwa | Kang, Mi-Jin | Jeong, Sekyoo | Lee, Eun | Cho, Hyun-Ju | Kim, Young-Ho | Yang, Song-I | Kim, Seo Hee | Hong, Soo-Jong | Halwani, Rabih | Al Muhsen, Saleh | Sultana, Asma | Al-Faraj, Achraf | Kanana, Rosan | Afzal, Sibtain | Al Kufaidi, Roaa | Kim, Hee-Kyoo | Oak, Chul-Ho | Choi, Gil-Soon | Moon, Ye-Jin | Park, Eun-Kee | Abrari, Mina | Amirzargar, Ali Akbar | Zarebidoki, Alireza | Ha, Mina | Hong, Soo-Jong | Seo, Ju-Hee | Kang, Mingyu | Cho, Byung-Ha | Park, Han-Ki | Park, Han-Ki | Kim, Kyung-Mook | Park, Chang-Han | Park, Heung Woo | Park, Heung Woo | Chang, Yoon-Seok | Chang, Yoon-Seok | Chang, Yoon-Seok | Song, Sook-Hee | Kim, Mi-Kyeong | Kim, Mi-Kyeong | Cho, Sang-Heon | Chang, Suk-Il | Min, Kyung-up | Min, Kyung-up | Morice, Alyn | Choi, Jungi | Han, Yusok | Park, Jin-Sung | Kwon, Eunmi | Kim, Chang-Keun | Sapartini, Gartika | Kim, Ji-Na | Shin, Seungwoo | Chang, Hun Soo | Shim, Eun-Young | Jun, Ji Ah | Lee, Hyeonju | Park, Jong-Sook | Park, Choon-Sik | Sepiashvili, Revaz | Khachapuridze, Darejan | Gamkrelidze, Sofio | Chikhladze, Manana | Lee, Seung-Eun | Kim, Yun-Seong | Jeon, Doo-Soo | Cho, Woo-Hyun | Yeo, Hye-Ju | Yoon, Seong-Hoon | Kim, Seung-Hyun | Lee, Taehyeong | Song, Hyun Ji | Park, Choon-Sik | Jun, Ji Ah | Park, Jong-Sook | Yoon, Dankyu | Kim, Yeon-Seop | Chang, Woo-Sung | Kang, Mi-Jin | Hong, Soo-Jong | Lee, Jeom-Kyu | Kim, Eun-Jin | Park, Minkee | Lee, Nanju Alice | Rost, Johanna | Muralidharan, Sridevi | Campbell, Dianne | Mehr, Sam | Lee, Seung-Hwa | Yoon, Seon-Joo | Kim, Ha-Jung | Lee, Eun | Yang, Song-I | Jung, Young-Ho | Yu, Ho-Sung | Kim, Hee-Suk | Park, Yeon Hee | Lee, So-Yeon | Park, Jun-Sung | Jun, Hyun Ok | Won, Ha Kyeong | Kang, Min-Koo | Moon, Sung Do | Kim, Byung-Keun | Kim, Ju-Young | Cho, Sang-Heon | Kang, Hye-Ryun | Shim, Ji-Su | Chung, Soo Jie | Choi, Jaehee | Ahn, Kangmo | Kim, Kwanghoon | Kim, Jihyun | Lee, Jiyoung | Park, Bo Bae | Nho, In Young | Park, Chang-Han | Kim, Jang Min | Chang, Suk-Il | Kim, Sun Kyung | Yang, Hyung Chae | Nam, Kwang Il | Lee, Jeongmin | Lee, Sooyoung | Jeong, Kyunguk | Jeon, Se-Ah | Fujiwara, Midori | Shindo, Shoko | Murota, Hiroyuki | Tahara, Mayuko | Takahashi, Aya | Katayama, Ichiro | Jung, Jae Woo | Song, Hyun Ji | Lee, Taehyeong | Jang, An-Soo | Park, Jong-Sook | Chang, Hun Soo | Park, Choon-Sik | Choi, Byoung Whui | Kim, Min-Hye | Bae, Da-Jeong | Song, Hyun Ji | Lee, Taehyeong | Jun, Ji Ah | Park, Jong-Sook | Jang, An-Soo | Chang, Hun Soo | Cho, Young Joo | Park, Choon-Sik | Mun, Sue Jean | Kuroda, Etsushi | Ozasa, Koji | Ishii, Ken | Kim, Sunmi | Park, Gyeong-Hun | Song, Hyun Ji | Lee, Taehyeong | Jun, Ji Ah | Chang, Hun Soo | Park, Jong-Sook | Park, Choon-Sik | Kim, Mi-Ae | Shin, Seungwoo | Park, Jong-Sook | Chang, Hun Soo | Cho, You Sook | Park, Hae-Sim | Park, Choon-Sik | Min, Zhang | Yoon, Seo Hee | Sol, In Suk | a Park, Young | Kim, Yoon Hee | Kim, Min Jung | Kim, Kyung Won | Sohn, Myung Hyun | Kim, Kyu-Earn | Shiquan, Wu | Lee, Yongwon | Bak, Hana | Ching, Maricar Wisco | Ramos, John Donnie | Jeong, Kyunguk | Lee, Sooyoung | Ahn, Kangmo | Sohn, Myung Hyun | Kim, Kyung Won | Lee, So-Yeon | Song, Tae Won | Jeon, Youhoon | Kim, Jihyun | Min, Taek Ki | Kim, Kyu-Earn | Pyun, Bok-Yang | Yang, Hyeon-Jong | Lee, Hae Ran | Ahn, Youngmin | Kwon, Ji-Won | Lim, Dae Hyun | Kim, Jeong Hee | Suh, Dongin | Ki, Hyung Young | Jeong, Kyunguk | Park, Byeong Sub | Lee, Sooyoung | Jeon, Se-Ah | Park, Kyu Jung | Yang, Song-I | Lee, Eun | Cho, Hyun-Ju | Kim, Young-Ho | Kang, Mi-Jin | Choi, Yean Jung | Choi, Kil Yong | Shin, Youn Ho | Ahn, Kangmo | Kim, Kyung Won | Kim, Byoung-Ju | Lee, So-Yeon | K, Eun-Jin | Dario, Roccatello | Liao, Jing | Feng, Yong | Shang, Yunxiao | Lee, Yongwon | Bak, Hana | Kim, Hyung Young | Kim, Byoung-Ju | Kwon, Ji-Won | Seo, Ju-Hee | Lee, Eun | Lee, So-Yeon | Yang, Song-I | Jung, Young-Ho | Kim, Hyo-Bin | Kwon, Ho-Jang | Park, Hee Ju | Min, Zhang | Guang-Min, Nong | Min, Jiang | Hur, Gyu Young | Sim, Eun Jung | Yoon, Sora | Choi, Juwhan | Kim, Junga | Sim, Jae Keom | Oh, Jee Youn | Jeong, Kyunguk | Park, Byeong Sub | Lee, Jeong-Min | Lee, Sooyoung | Cheon, Eunjae | Na, Youngjoo | Park, Kyu Jung | Lee, Eunjoo | Yang, William | Kelly, Suzanne | Perrins, Rob | Yang, Jimmy | Yang, William | Kelly, Suzanne | Perrins, Rob | Karsh, Jacob | Yang, Jimmy | Badellino, Hector | Teijeiro, Alvaro | Cuello, Mabel | Pereira, Marilyn Urrutia | Egues, Gustavo | Aktas, Ayse | Chun, Jin-Kyong | Mujuru, Hilda Angela | Sibanda, Elopy N. | Popescu, Andreea Ioana | Greblescu, Raluca | Rahman, Suheyla | Aktas, Ayse | Tataurshchikova, Nataly | Dissanayake, Eishika | Inoue, Yuzaburo | Shimojo, Naoki | Nakano, Taiji | Tanjung, Conny | Jensen-Jarolim, Erika | Fazekas, Judit | Singer, Josef | Lukschal, Anna | Horvat, Reinhard | Achatz-Straussberger, Gertrude | Achatz, Gernot | Fujita, Yuji | Ikegami, Shuji | Nakamura, Yoshitaka | Inoue, Yuzaburo | Shimojo, Naoki | Kohno, Yoichi | Suzuki, Shuichi | Ozawa, Naoko | Kubota, Takayuki | Nonaka, Ken | Ohara, Osamu | Masuda, Kentaro | Rhee, Chin Kook | Lee, Sook Young | Lee, Hwa Young | Lee, Hea Yon | Kang, Ji Young | Kim, Sei Won | Kwon, Soon Seog | Kim, Young Kyoon | Kim, Gun-Woo | Kim, Ju-Young | Cho, Sang-Heon | Cho, Sang-Heon | Kang, Hye-Ryun | Kang, Hye-Ryun | Kim, Hyo-Soo | Han, Jung Gyu | Lee, Jin | Lee, Ji Young | Go, Ji Young | Park, So Jung | Kim-Chang, Julie | Love, Cassandra | Lugar, Patricia | Citraresmi, Endah | Kaswandani, Nastiti | Utami, Cynthia | Said, Mardjanis | Jung, Young-Ho | Yang, Song-I | Kim, Byoung-Ju | Kwon, Ji-Won | Kim, Hwan-Cheol | Leem, Jong-Han | Seo, Ju-Hee | Kim, Hyung Young | Lee, So-Yeon | Kwon, Ho-Jang | Kim, Hyo-Bin | Cho, Hyun-Ju | Yamazaki, Susumu | Nakano, Nobuhiro | Honjoh, Asuka | Inage, Eisuke | Baba, Yosuke | Ohtsuka, Yoshikazu | Shimizu, Toshiaki | M., Ishaq | Khan, Sameera M. I. | Khan, Imran | Khan, Sabeen | Loo, Evelyn Xiu Ling | Goh, Anne | Teoh, Oon Hoe | Chan, Yiong Huak | Saw, Seang Mei | Kwek, Kenneth | Gluckman, Peter D | Godfrey, Keith M | Van Bever, Hugo | Chong, Yap Seng | Lee, Bee Wah | Shek, Lynette | Lee, Alison Joanne | Rossi, Daniela | Nemeth, Agnes | Sehlinger, Torsten | Bergmann, Karl-Christian | Goergen, Frank | Ehlayel, Mohammad S. | Bener, Abdul Bari | Chu, Hieu Chi | Do, Nga Thi Quynh | Van Nguyen, Dinh | Nguyen, Ha Thi Thu | Le, Huong Thi Minh | Van Nunen, Sheryl | Vidal, Christopher | Fernando, Suran | Psarros, Fotis | Syrigou, Ekaterini | Politi, Ekaterini | Chrysoulakis, Spyridon | Vourdas, Dimitrios | Petalas, Konstantinos | Saha, Mouli | Bhattacharya, Kashinath | Jain, Subir | Song, Xiaolian | Lin, Haiyan | Nishikawa, Kyohei | Shimada, Takashi | Yasueda, Hiroshi | Enomoto, Tadao | Aizawa, Daisuke | Kobayashi, Takayoshi | R., Chellaa | Jain, Subir | Jain, Subir | Yudina, Marina | M., Ishaq | Khan, Sameera M. I. | Khan, Imran | Khan, Sabeen | Saito, Mayako | Sari, Nurul Iman Nilam | Kim, Jae Young | Song, Jaechul | Kim, Inah | Lee, Kyeong Joon | Park, Soo Jin | Roh, Soo Yong | Billamay, Somxay | Udin, Muchammad Fahrul | Han, Mae Ja | Oh, Jae-Won | Kim, Kyu Rang | Kim, Baek-Jo | Mazza, Jorge A. | Ko, Jason Kangeun | Huang, David J. T. | Furuya, Kanae | Kainuma, Keigo | Ito, Takahiro | Nagao, Mizuho | Fujisawa, Takao | Hirayama, Junya | Kuwahara, Yu | Qualizza, Rosanna | Incorvaia, Cristoforo | Maraschini, Anna | Hasnain, Syed Mohammed | Al-Frayh, Abdulrahman | Hartog, Anita | Bastiaans, Jacqueline | Loonstra, Reinilde | Rutten, Lieke | Harthoorn, Lucien | Van Bergenhenegouwen, Jeroen | Garssen, Johan | Yoo, Kwang-Ha | Cho, Sang-Heon | Ghoshal, AG | Muttalif, Abdul Razak Bin Abdul | Lin, Horng- Chyuan | Thanaviratananich, Sanguansak | Bagga, Shalini | Faruqi, Rab | Baidya, Santwona | Taylor, Colman | Wang, De Yun | Ahn, Hae-Ryun | Hong, Soon-Kwan | Kim, Jong-Woong | Nam, Gui-Hyun | Kim, Mee-Ja | Park, Jae-Kyoung | Yi, Myung-Hee | Jeong, Kyoung Yong | Kim, Ju-Yeong | Yong, Tai-Soon | Kim, Bum Joon | Joo, Hs | Lim, Kj | Lee, Jae-Hyun | Park, Jung-Won | Yoon, Kh | Choi, DS | Joo, Hanseung | Kim, Bum Joon | Lim, Kj | Kim, MJ | Choi, DS | Yoon, Kh | Kim, Bum Joon | Joo, Hanseung | Jung, Woo Sang | Lim, Kj | Choi, DS | Lee, Ji-Hoon | Kwon, Soon-Chan | Lee, Soo-Jin | Roh, Soo Yong | Kim, Hogil | Lee, Kyeong Joon | Van De Loo, Aurora | Fernstrand, Amanda | Garssen, Johan | Verster, Joris | Van De Loo, Aurora | Garssen, Johan | Verster, Joris | Golez, Jasmina | Ozasa, Koji | Kuroda, Etsushi | Ishii, Ken | Imran, Muhammad | Gierer, Selina | Martinez, John | Wong, Lydia | Lee, Bee Wah | Yap, Gaik Chin | Llanora, Genevieve | Thong, Bernard | Shek, Lynette | Ehlayel, Mohammad S. | Soliman, Ashraf | Martins, Pedro | Marques, João | Gomes-Belo, Joana | Palmeiro, Teresa | Caires, Iolanda | Belo, Joana | Botelho, Maria Amália | Leiria-Pinto, Paula | Neuparth, Nuno | Suratannon, Narissara | Mekaroonkamol, Jaichat | Ngamphaiboon, Jarungchit | Lertchanaruengrith, Piyawadee | Chatchatee, Pantipa | Kardar, Gholamali | Majd, Ahmad | Shahali, Youcef | Ghahremaninejad, Farrokh | Pourpak, Zahra | Mousavi, Fateme | Sadeghi-Shabestari, Mahnaz | Van Bilsen, K. | Manusama, O. | Dik, W.a. | Van Der Burg, M. | Van Der Velden, V. H. J. | Dalm, V.a.S. H. | Van Hagen, P. M. | Liu, Yongping | Jeong, Yi Yeong | Kim, Ji Hye | Yoon, Moon Gyeong | Ye, Young Min | Shin, Yoo Seob | Ban, Ga Young | Park, Hae-Sim | Jung, Hye Min | Roh, Soo Yong | Song, Jaechul | Lee, Ji-Hoon | Kim, Hogil | Kim, Jae Young | Lee, Kyeong Joon | Wong, Lydia | Rajakulendran, Mohana | Santhanam, Haripriya | Shek, Lynette | Lim, Tow Keang | Kim, Hogil | Lee, Soo-Jin | Lee, Ji-Hoon | Roh, Soo Yong | Kwon, Soon-Chan | Wistiani, Ani | H, Galuh | Kardar, Gholam Ali | Sharifshoushtari, Maryam | Majd, Ahmad | Nejadsattari, Taher | Pourpak, Zahra | Moin, Mostafa | Kim, Ji Hye | Seo, Daehong | Ye, Young Min | Park, Hae-Sim | Park, Jung-Won | Lee, Jae-Hyun | Shin, Yoo Seob | Kowalski, Marek L. | Wardzynska, Aleksandra | Kurowski, Marcin | Pawelczyk, Malgorzata/Ewa | Wysokinski, Adam | Kloszewska, Iwona | Grzegorczyk, Janina | Piotrowski, Wojciech | Makowska, Joanna | Kwon, Soon-Chan | Song, Jaechul | Kim, Yong-Kyu | Bostanci, Ilknur | Emeksiz, Zeynep Sengul | Ertugrul, Aysegul | Ozmen, Serap | Sahin, Soner | Kim, Sang-Ha | Lee, Myoung Kyu | Lee, Won Yeon | Yong, Suk Joong | Lee, Seok Jeong | Jung, Ye-Ryung | Kim, Myung Shin | Park, Jong-Sook | Jang, An-Soo | Park, Choon-Sik | Wulandari, Diah Asri | Kartasasmita, Cissy | Yani, Finny Fitry | Machmud, Rizanda | Lestari, Dhina Lydia | Rusdi, Rusdi | Yurmalina, Yurmalina | Darwin, Eryati | Bostanci, Ilknur | Karacan, Gulin | Ercan, Nazli | Colak, Asuman | Alisik, Murat | Basarir, Gulay | Erel, Ozcan | Bostanci, Ilknur | Keskin, Yasemin | Lopata, Andreas/Ludwig | Zenger, Kyall | Nugraha, Roni | Kamath, Sandip | Bielory, Leonard | Georgopoulos, Panos | Zhang, Yong | Mi, Wheat | Cai, Ting | Xian, MO | Li, Jing | Feng, Mulin
Table of Contents
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
Jae-Min Shin, Heung-Man Lee, Il-Ho Park
A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines
Hyun-Sun Yoon, Gyeong Yul Park
A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome
Margit Zeher
A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendritic cells
Katsuhiko Matsui, Saki Tamai, Reiko Ikeda
A5 An evaluation of variousallergens in cases of allergic bronchial asthma at lucknow and neighbouring districts by intradermal skintest
Drsushil Suri, Dranu Suri
A6 Evaluation ferqency of ADHD in childhood asthma
Marzieh Heidarzadeh Arani
A7 Steven johnson syndrome caused by typhoid fever in a child
Azwin Lubis, Anang Endaryanto
A8 Chronic Bronchitis with Radio Contrast Media Hypersensitivity: A Case with Hypothesized GINA Step 1 Asthma
Shinichiro Koga
A9 The association between asthma and depression in Korean adult : An analysis of the fifth korea national health and nutrition examination survey (2010-2012)
Lee Ju Suk
A10 Management of allergic disease exacerbations in pregnancy
Yasunobu Tsuzuki
A11 Subcutaneous immunotherapy mouse model for atopic dermatitis
Seo Hyeong Kim, Jung U Shin, Ji Yeon Noh, Shan Jin, Shan Jin, Hemin Lee, Jungsoo Lee, Chang Ook Park, Kwang Hoon Lee, Kwang Hoon Lee
A12 Atopic disease and/or atopy are risk factors for local anesthetic allergy in patients with history of hypersensitivity reactions to drugs?
Fatma Merve Tepetam
A13 Food hypersensitivity in patients with atopic dermatitis in Korea
Chun Wook Park, Jee Hee Son, Soo Ick Cho, Yong Se Cho, Yun Sun Byun, Yoon Seok Yang, Bo Young Chung, Hye One Kim, Hee Jin Cho
A14 Anaphylaxis caused by an ant (Brachyponera chinensis) in Japan
Yoshinori Katada, Toshio Tanaka, Akihiko Nakabayashi, Koji Nishida, Kenichi Aoyagi, Yuki Tsukamoto, Kazushi Konma, Motoo Matsuura, Jung-Won Park, Yoshinori Harada, Kyoung Yong Jeong, Akiko Yura, Maiko Yoshimura
A15 Anti-allergic effect of anti-IL-33 by suppression of immunoglobulin light chain and inducible nitric oxide synthase
Tae-Suk Kyung, Young Hyo Kim, Chang-Shin Park, Tae Young Jang, Min-Jeong Heo, Ah-Yeoun Jung, Seung-Chan Yang
A16 Food hypersensitivity in patients with chronic urticaria in Korea
Hye One Kim, Yong Se Cho, Yun Sun Byun, Yoon Seok Yang, Bo Young Chung, Jee Hee Son, Chun Wook Park, Hee Jin Cho
A17 Dose optimizing study of a depigmented polymerized allergen extract of phleum pollen by means of conjunctival provocation test (CPT)
Angelika Sager, Oliver Pfaar
A18 Correlation of cutaneous sensitivity and cytokine response in children with asthma
Amit Agarwal, Meenu Singh, Bishnupda Chatterjee, Anil Chauhan
A19 Colabomycin E, a Streptomycete-Derived Secondary Metabolite, Inhibits Proinflammatory Cytokines in Human Monocytes/Macrophages
Ilja Striz, Eva Cecrdlova, Katerina Petrickova, Libor Kolesar, Alena Sekerkova, Veronika Svachova, Miroslav Petricek
A20 Intravenous immunoglobluin treatment in a child with resistant atopic dermatitis: A brief review on this therapeutic regimen
Hyuck Hoon Kwon, Kyu Han Kim
A21 Wheat allergy is difficult to diagnose then other food allergens
Suman Kumar
A22 The effects of spirulina (Arthrospira platensis) dietary supplement as an adjunct therapy for children aged 7 to 14 years old with asthma: A randomized - double blind placebo controlled clinical trial
Lou Ver Leigh Arciaga Manzon, Pilar Agnes Gonzalez Andaya
A23 The study about cause and clinicopathological findings of injection induced dermatitis
Bark-Lynn Lew, Youngjun Oh, Dongwoo Suh, Woo-Young Sim
A24 IgE reactivity of recombinant allergen pac c 3 of the Asian needle ant pachycondyla chinensis
Kyoung Yong Jeong, Myung-Hee Yi, Mina Son, Dongpyo Lyu, Jae-Hyun Lee, Tai-Soon Yong, Chein-Soo Hong, Jung-Won Park
A25 Characterization of specific IgE antibody related to antigen 5 of echinococcus granulosus
Mohammadreza Siavashi
A26 Development of binary forecast model of asthma exacerbation: Asthma index
Hey Suk Yun, Ha-Na Kang, Jae-Won Oh, Young Jin Choi
A27 Different levels in rantes, IL-5 and TNF-á between the nasal polyps of adolescents with allergic, local allergic and non-allergic rhinitis
Ha-Na Kang, Jae-Won Oh, Young Jin Choi
A28 Tgfβ1 level is associated with VDR gene polymorphism in children with allergy diseases
Tatiana Sentsova, Ilya Vorozhko, Olga Chernyak, Vera Revyakina, Anna Timopheeva, Andrey Donnikov
A29 Dynamics of immunological biomarkers in children with food allergy fed goat milk formula
Tatiana Sentsova, Ilya Vorozhko, Olga Chernyak, Vera Revyakina, Anna Timopheeva
A30 Association between obesity, abdominal obesity and adiposity and the prevalence of atopic dermatitis in young Korean adults: The korea national health and nutrition examination survey, 2008–2010
Ji Hyun Lee, Young Min Park, Sang Soo Choi, Kyung Do Han, Han Mi Jung, Young Hoon Youn, Jun Young Lee, Yong Gyu Park, Seung-Hwan Lee
A31 Associations of natural history and environmental factors with asthma among children in rural and urban areas of guangdong, China
Zhaowei Yang, Jing Li, Mulin Feng, Marjut Roponen, Bianca Schaub, Gary WK Wong
A32 The effect of CO2-enriched atmospheres to producing of allergenic pollen by ragweed
Young Jin Choi, Ha-Na Kang, Jae-Won Oh
A33 Application evaluation of house dust mite and components specific-IgE and IgG4 in specific immunotherapy with allergic diseases
Baoqing Sun, Peiyan Zheng
A34 Effect of Asian dust events on asthma according to the socioeconomic status using claim data in KOREA
Yoon-Sung Park
A35 TSLP downregulates human â-defensin 2 through STAT3-dependent pathway in keratinocytes
Sang Wook Son
A36 Effects of anti-IgE on IL-4, IL-5, IL-17, and CD19,20,200 in a case of netherton syndrome (SPINK5 mutation)
Arzu Didem Yalcin, Sukran Kose, Kemal Kiraz
A37 Augmentation of arginase 1 expression exacerbates airway inflammation in murine asthma models
Jin-Young Lee, Sehyo Yune, Jae-Won Paeng, Mi-Jung Oh, Byung-Jae Lee, Dong-Chull Choi, Young Hee Lim, Kyoung Won Ha
A38 Caregivers of children with no food allergy – their experiences and perception of the condition
Kiwako Yamamoto-Hanada, Masami Narita, Masaki Futamura, Yukihiro Ohya
A39 Evaluation of Drug Provocation Tests in Korean Children: A Single Center Experience
Jihyun Kim, Jinwha Choi, Kwanghoon Kim, Jaehee Choi, Kangmo Ahn
A40 Danyoung classification 2015 update by digital HD endoscopic evaluation
SUN-HO/Brian Chang
A41 Effect on quality of life of the mixed house dust mite/weed pollen extract immunotherapy in polysensitized patients
Lisha Li
A42 Ambient desert dust and allergic symptoms: A time series analysis from a national birth cohort (JECS)
Kumiko Tsuji Kanatani, Yu-Ichi Adachi
A43 Individuals Allergic to Cow’s Milk Should be Vigilant When Consuming Beef Because It May be Injected Beef
Shigeyuki Narabayashi, Ikuo Okafuji, Yuya Tanaka, Satoru Tsuruta, Nobue Takamatsu
A44 Quality of life of chronic rhinosinusitis patients with or without nasal polyps in Korea
Soo Whan Kim, Do Hyun Kim
A45 House dust mite sensitization and exacerbation of asthma in the fall in children
Jong-Seo Yoon, Jin Tack Kim, Hwan Soo Kim, Yoon Hong Chun, Hyun Hee Kim, Sul Mui Won
A46 Evidence-based health advice for childhood eczema and household pets
Kam Lun E. Hon, Chung Mo Chow, Ting Fan Leung
A47 Relationship between allergic rhinitis and mental health in korea
Do Hyun Kim, Soo Whan Kim
A48 Oscillometric bronchodilator response in 3 to 5 years old healthy and asthmatic Filipino children
Gemmalyn Esguerra, Emily Resurreccion, Kristine Elisa Kionisala, Jenni Rose Dela Cruz
A49 The use of aeroallergen immunotherapy to treat eosinophilic esophagitis
Muhammad Imran
A50 A study of the eczema herpeticum in Korean
Yun Seon Choe, Kyu Han Kim, Mira Choi
A51 Specific sublingual immunotherapy in Korean patients with atopic dermatitis
Byung Soo Kim, Hyun-Joo Lee, Jeong-Min Kim, Jeong-Min Kim, Gun-Wook Kim, Je-Ho Mun, Je-Ho Mun, Hoon-Soo Kim, Margaret Song, Hyun-Chang Ko, Hyun-Chang Ko, Moon-Bum Kim
A52 Association between polymorphisms in bitter taste receptors genes and clinical features in Korean asthmatics
Sun-Young Yoon
A53 Effect of glycosides based standardized fenugreek seed extract in bleomycin-induced pulmonary fibrosis in rats
Amit Kandhare
A54 A kampo formula, ogi-kenchu-to, decreases side-effects of steroid ointment for infantile atopic dermatitis: Three cases report
Noriko Yahiro
A55 To test use of jet nebulizers NE-C802 as a drug delivery system in the children with asthma
Amit Agarwal, Meenu Singh, Jasleen Kaur, Ruby Pawankar, Pankaj Pant, Sukhmanjeet Singh
A56 Immunoglobulin e to allergen components of house dust mite in Korean children with allergic disease
Hwan Soo Kim, Jong-Seo Yoon, Sul Mui Won, Yoon Hong Chun, Jin Tack Kim, Hyun Hee Kim
A57 Effectiveness of premedication and rapid desensitization in hypersensitivity to l-asparaginase
Hwan Soo Kim, Sul Mui Won, Yoon Hong Chun, Jong-Seo Yoon, Hyun Hee Kim, Jin Tack Kim
A58 Angioedema with Eosinophilia: The First Report from Thailand
Thatchai Kampitak
A59 Evaluation of anti-pruritic and anti-inflammatory effects of Korean red ginseng extract on atopic dermatitis murine model
So Min Kim, Hyun Joo Lee, Hei Sung Kim, Jeong Deuk Lee, Sang Hyun Cho
A60 Subcutaneous autologous serum therapy in chronic urticaria
Kiran Godse
A61 Allergic bronchopulmonary aspergillosis in asthma and lung tuberculosis
Juwita Soekarno, Sarie Ratnasari, E. Alwi Datau, Eko Surachmanto, JC Matheos
A62 Infantile eczema is associated with campylobacter and roseburia subpopulations but not microbial diversity in stool samples of Chinese newborns
Ting Fan Leung, Jamie Sui-Lam Kwok, Christine Kit-Ching Tung, Man Fung Tang, Stephen Kwok-Wing Tsui, Gary WK Wong, Kam Lun Ellis Hon, Wing Hung Tam, Hing Yee Sy
A63 Association between serum chitinase level and toll-like receptor polymorphisms in bakery workers
Sohee Lee
A64 IFN-gamma contributes to nasal polypogenesis by inducing epithelial-to-mesenchymal transition via non-smad pathway
Hyun-Woo Shin, Mingyu Lee, Dae Woo Kim, Roza Khalmuratova
A65 Management and education status of anaphylaxis patients who visit our emergency room (ER)
Mi Yeoung Kim, Jaewon Jeong, Chansun Park
A66 Hypoallergen-Encoding DNA Plasmids As Immunoprophylactic Vaccines of Shrimp Tropomyosin Hypersensitivity
Christine Yee Yan Wai, Patrick S.C. Leung, Nicki Y.H. Leung, Ka Hou Chu
A67 The relationship between sputum pentraxin 3 levels and childhood asthma
Hee Seon Lee, Kyung Eun Lee, Jung Yeon Hong, Mi Na Kim, Min Jung Kim, Yoon Hee Kim, In Suk Sol, Seo Hee Yoon, Kyung Won Kim, Myung Hyun Sohn, Kyu-Earn Kim
A68 The role of local antibody responses in the nasal inflammation of allergic rhinitis (AR) patients
Ji Hye Kim, Hae-Sim Park, Yoo Seob Shin, Young Min Ye, Daehong Seo, Moon Gyeong Yoon, Young Mok Lee
A69 A case of ofloxacin-induced anaphylaxis by non-IgE, but specific IgG4-mediated responses
Daehong Seo, Ji Hye Kim, Young-Mok Lee, Young Min Ye, Hae-Sim Park
A70 Serum LTE4 metabolite as a biomarker for aspirin exacerbated respiratory disease
Ga Young Ban, Kumsun Cho, Seung-Hyun Kim, Yong Eun Kwon, Moon Gyeong Yoon, Ji Hye Kim, Yoo Seob Shin, Young Min Ye, Dong-Ho Nahm, Hae-Sim Park
A71 Local and systemic reactions of dust mite subcutaneous immunotherapy (SCIT) among children in a tertiary care hospital
Pilar Agnes Gonzalez Andaya
A72 Effects of carboxymethyl glucan (CM-glucan) in children with allergic rhinitis and asthma: A randomized controlled trial
Pilar Agnes Gonzalez Andaya
A73 Autophagy mechanisms in patients with severe asthma: A new therapeutic target
Ga Young Ban, Chang Gyu Jung, Seung-Ihm Lee, Duy Le Pham, Dong-Hyeon Suh, Eun-Mi Yang, Young Min Ye, Yoo Seob Shin, Hae-Sim Park
A74 Aggravation of airway inflammation and hypperresponsiveness following nasal challenge with dermatophagoides pteronyssinus in perennial allergic rhinitis patients without symptoms of asthma
Wan Jun Wang, MO Xian, Yan Qing Xie, Jing Ping Zheng, Jing Li
A75 Serum 25-hydroxyvitamin d in early childhood is non-linearly associated with allergy
Emma Merike Savilahti, Outi Mäkitie, Anna Kaarina Kukkonen, Sture Andersson, Heli Viljakainen, Erkki Savilahti, Mikael Kuitunen
A76 Fric test in dermographism
Kiran Godse
A77 Neutrophil autophagy and extracellular trap could contribute to asthma severity
Duy Le Pham, Ga Young Ban, Seung-Hyun Kim, Eun-Mi Yang, Hae-Sim Park, Ji-Ho Lee, Yong-Joon Chwae
A78 Redox Modulation for the Treatment of Toluene Diisocyanates-Induced Lung Inflammation
Li-Ming Chin, Chi-Chang Shieh
A79 A case of occupational asthma and rhinitis with anaphylaxis to Korean ginseng and sanyak
Ji Hye Kim, Hye-Soo Yoo, Moon Gyeong Yoon, Ga Young Ban, Ga Young Ban, Yoo Seob Shin, Young Min Ye, Hae-Sim Park
A80 Factors of influencing epidermal permeability barrier defects in atopic dermatitis children
Myong Soon Sung, Jin Uck Choi, Sung Won Kim, Yong Jin Hwang
A81 Innate type 2 response to aspergillusfumigatus in a murine model of atopic dermatitis-like skin inflammation
Arum Park, Eun Lee, Song-I Yang, Hyun-Ju Cho, Jinho Yu
A82 Activin a receptor 1C may implicate in the development of sensitive skin
Dong Hun Lee, Eun Ju Kim, Yeon Kyung Kim, Eun Jin Doh, Hee Chul Eun, Jin Ho Chung, Young Mee Lee, Seon Pil Jin
A83 Genetic association and eQTL analyses of genes associated with allergy in atopic/non-atopic asthma
Xingnan Li, Naftali Kaminski, Sally Wenzel, Eugene Bleecker, Deborah Meyers
A84 Gastroscope feature and clinical characteristics in 172 cases of children with henoch-schonlein purpura
Zeng Huasong
A85 The role of TRPV1 in CD4+ t cell mediated inflammatory response of allergic rhinitis
Ji-Hun Mo, Ramachandran Samivel, Eun-Hee Kim, Ji-Hye Kim, Jun-Sang Bae, Young-Jun Chung, Dae Woo Kim
A86 A Phenotype of Rhinitis from School Children Is Associated with the Development of Bronchial Hyperresponsiveness
Eun Lee, Si Hyeon Lee, Young-Ho Kim, Hyun-Ju Cho, Ho-Sung Yu, Mi-Jin Kang, Song-I Yang, Young-Ho Jung, Hyung Young Kim, Ju-Hee Seo, Byoung-Ju Kim, Hyo-Bin Kim, So-Yeon Lee, Ho-Jang Kwon, Soo-Jong Hong
A87 Increased basal activation status was noted in adult anaphylaxis patients
Sailesh Palikhe, Hae-Sim Park, Seung-Hyun Kim, Ji Hye Kim, Eun-Mi Yang
A88 Clinical values of interferon-gamma enzyme-linked immunospot assays for management of antibiotic hypersensitivity in hospitalized patients
Suda Sibunruang, Jettanong Klaewsongkram
A89 VDR gene polymorphism and 25-hydroxy vitamin d levels in children with food allergy
Tatiana Sentsova, Ilya Vorozhko, Anna Timopheeva, Olga Chernyak, Vera Revyakina, Andrey Sokolnikov
A90 An analysis of 145 oral almond challenge tests
Makoto Nisihino, Yu Okada, Noriyuki Yanagida, Motohiro Ebisawa, Sakura Sato, Kiyotake Ogura, Tomoyuki Asaumi, Kenichi Nagakura, Tetsuharu Manabe, Hirotoshi Unno
A91 Effect of creatine supplementation in fish allergenic potential; A proteomics study
Pedro M Rodrigues, Denise Schrama, Gadija Mohamed, Lizex Hüsselmann, Lizex Hüsselmann, Bongani Ndimba
A92 Flagellin modulates the function of invariant NKT cells via dendritic cells in asthma patients
Jae-Uoong Shim, Young Il Koh, Joon Haeng Rhee, Ji-Ung Jeong
A93 Clinical and subclinical manifestations of allopurinol – induced severe cutaneous adverse reactions in Vietnam
Dinh Van Nguyen, Hieu Chi Chu, Mui Thi Tran, Christopher Vidal, Suran Fernando, Sheryl Van Nunen, Sy Van Than
A94 Time course of serum inhibitory activity for facilitated allergen-IgE binding during house dust mite immunotherapy
Mulin Feng, Jing Li
A95 Periostin is a novel biomarker in eosinophilic nasal polyps of chronic rhinosinusitis
Dong-Kyu Kim, Seung-No Hong, Kyoung Mi Eun, Hong Ryul Jin, Dae Woo Kim
A96 Dominance of Th1-response in children with refractory mycoplasma pneumoniae pneumonia
Jun Bao, Yi-Xiao Bao
A97 Studies on the role of CD14 polymorphism among pollen and mold induced asthmatics of kolkata, India
Sanjoy Podder, Goutam Kumar, Shampa Dutta, Amlan Ghosh
A98 House dust mite allergy – Indian perspective
Goutam Kumar Saha, Sanjoy Podder, Salil Kumar Gupta
A99 Increased expression of purinergic (P2Y12) receptor and cysteinyl leukotriene receptors in the lung tissue of a mouse model of allergic asthma
Tu/Hoang Kim Trinh, Yoo Seob Shin, Hae-Sim Park, Jing-Nan Liu, Duy Le Pham
A100 Autologous serum skin test in chronic idiopathic urticaria - relationship with autoimmune markers and disease severity
Hyun-Chang Ko, Byung Soo Kim, Moon-Bum Kim
A101 Anxiety and depression levels in severe asthma patients treated with omalizumab
Ömer Özbudak, Fatih Üzer
A102 Economic burden of refractory chronic spontaneous urticaria on Kuwait health system
Mona Al-Ahmad, Maryam Alowayesh, Norman Carroll
A103 IgE-mediated maize allergy in India: A 28 kd protein responsible for food-induced allergic reaction
Anand Bahadur Singh
A104 Liposomal encapsulation of house dust mite allergens and dexamethasone modulates allergic response in a murine model of asthma
Yordanis Pérez-Llano, María Del Carmen Luzardo Lorenzo, Wendy Ramírez González, Carlos Calcines Cruz, Rady Laborde Quintana, Alain Morejón, Virgilio Bourg, Marilé Hechavarría Stoker
A105 Immune Suppressive Effects of Tonsil-Derived Mesenchymal Stem Cells for Eosinophilic Rhinosinusitis with Nasal Polyps in a Mouse Model
Jun-Sang Bae, Ramachandran Samivel, Eun-Hee Kim, Ji-Hye Kim, Ji-Hun Mo
A106 Second line treatments of dermographic urticaria refractory to antihistamines
Keiko Hanaoka, Michihiro Hide, Akio Tanaka, Makiko Hiragun, Mikio Kawai
A107 Diagnostic Value of Specific IgE to Peanut and Ara h 2 in Korean Children with Peanut Allergy
Kwanghoon Kim, Kwanghoon Kim, Hye-Young Kim, Jihyun Kim, Kangmo Ahn, Youngshin Han
A108 Inappropriate amounts of topical tacrolimus applied on Korean patients with eczema
Gun-Wook Kim, Hyun-Chang Ko, Byung Soo Kim, Moon-Bum Kim, Margaret Song
A109 Identification of an IgG1-mediated anaphylaxis marker and its application in evaluating the antigenicity of infant formulas
Takeshi Matsubara, Hiroshi Iwamoto, Yuki Nakazato, Kazuyoshi Namba, Yasuhiro Takeda
A110 Nitric oxide as a screening tool for evaluation of postoperative state of chronic rhinosinusitis
Jae Hoon Lee, Woo Yong Bae
A111 Comparison of different medical treatment options for crswnp: Doxycycline, methylprednisolone, mepolizumab, omalizumab
Els De Schryver, Lien Calus, Philippe Gevaert, Thibaut Van Zele, Claus Bachert
A112 Successful treatment of steroid resistant asthma model by blocking CD28 signal
Akio Mori, Satoshi Kouyama, Miyako Yamaguchi, Yo Iijima, Akemi Abe-Ohtomo, Hiroaki Hayashi, Kentaroh Watai, Chihiro Mitsui, Chiyako Oshikata, Kiyoshi Sekiya, Takahiro Tsuburai, Mamoru Ohtomo, Yuma Fukutomi, Masami Taniguchi
A113 Serum periostin levels was not associated with allergic rhinitis and allergic sensitization in Korean children
Ju Wan Kang, Jeong Hong Kim, Jeong Hong Kim, Keun-Hwa Lee, Hye-Sook Lee, Seong-Chul Hong, Jaechun Lee
A114 Roles of ADAM10 and ADAM17 in allergic rhinitis
Ji Won Seo, Jae Hoon Lee, Woo Yong Bae
A115 Mechanism of oral and topical polyprenol action in atopic dermatitis
Ivans Sergejs Kuznecovs, Galina Kuznecova
A116 Technical and clinical validation of a mobile chamber for allergen exposure tests
Karl-Christian Bergmann, Torsten Zuberbier, Joseph Salame, Torsten Sehlinger, Georg Bölke
A117 The association between serum lead level and total immunoglobulin e according to allergic sensitization
Yoo Suk Kim, Jung Hyun Chang, Jeong Hong Kim, Ju Wan Kang
A118 Clinical and laboratory characteristics of nasal obstruction dominant allergic sensitization
Seung-No Hong, Doo Hee Han, Chae-Seo Rhee
A119 Nasal provocation test is useful for the diagnoses of allergic, non- allergic, and local allergic rhinitis
Young-Joo Ko, Young Hyo Kim, Dae-Young Kim, Tae Young Jang
A120 Aspirin facilitates the intestinal absorption and oral sensitization of food allergens in rats
Tomoharu Yokooji, Taiki Hirano, Hiroaki Matsuo
A121 Gestational Secondhand Smoke Exposure Could Affect Maternal n-Glycosylation and Cause Filaggrin Loss in Children with Atopic Dermatitis
Galina Kuznecova, Ivans Sergejs Kuznecovs
A122 Allergen specific immunotherapy in the treatment of allergic rhinitis and asthma--a randomized prospective study from kashmir valley-north of India
Roohi Rasool Wani, Shafia Alam Syed, Ghulam Hassan, Ayaz Gul, Saniya Nissar, Zaffar Amin Shah
A123 Sleep disorders in latin-American children with asthma and/or allergic rhinitis and normal controls
Marilyn Urrutia Pereira, Carmen Fernandez, Dirceu Sole, Herberto Jose Chong Neto, Veronica Acosta, Alfonso Mario Cepeda, Mirta Alvarez Castello, Claudia Almendarez, Jose Santos Lozano Saenz, Juan C. Sisul, Nelson Rosario Filho, Antonio Castillo, Marylin Valentin Rostan, Jennifer Avila, Hector Badellino, Maria Carolina Manotas, Raúl Lázaro Castro Almarales, Mayda González León
A124 Association between respiratory symptoms and exhaled nitric oxide in Afghanistan
Woo Kyung Kim, Hae-Sun Yoon
A125 ATP, a danger signal, activates human eosinophils via P2 purinergic receptors
Takehito Kobayashi, Tooru Noguchi, Tomoyuki Soma, Kazuyuki Nakagome, Hidetomo Nakamoto, Hirohito Kita, Makoto Nagata
A126 Atopic dermatitis and sleep disorders in latin American children
Marilyn Urrutia Pereira, Dirceu Sole, Herberto Jose Chong Neto, Alfonso Mario Cepeda, Raúl Lázaro Castro Almarales, Juan C. Sisul, Marylin Valentin Rostan, Hector Badellino, Miguel Alejandro Medina Avalos, Antonio Castillo, Claudia Almendarez, Nelson Rosario Filho, Caridad Sanchez Silot, Jennifer Avila, Felicia Berroa Rodriguez, Jose Santos Lozano Saenz, Mirta Alvarez Castello, Carmen Fernandez
A127 Der p 23: A Major House Dust Mite Allergen in Spite of Limited Release from Fecal Pellets and Prominent Protease Sensitivity
Wai Tuck Soh, Alain Jacquet, Kiat Ruxrungtham, Emmanuel Nony, Maxime Le Mignon
A128 Anaphylactic Reaction After Inhalation of Budesonide
Mary Lee-Wong, Suzanne McClelland, Suzanne McClelland, Nanette B. Silverberg, Christian E. Song
A129 Lipidomic analysis of mattress dust from urban and rural schoolchildren in China
Zhaowei Yang, Jiukai Zhang, Wentao Zheng, Nanshan Zhong, Jing Li
A130 Improvements in quality of life in children with allergic rhinitis after adenotonsillectomy
Jung Ho Bae, Young Joo Cho, Joo Yeon Kim
A131 The seasonal variation of asthma exacerbations in patients allergic to pollens in Greece
Konstantinos Petalas, Dimitrios Vourdas, Christos Grigoreas
A132 Whole-genome sequencing study in allergic rhinitis nuclear families
Yuan Zhang
A133 Effect of the production of extracellular matrix from nasal fibroblasts by eosinophils activated with airborne fungi
Seung-Heon Shin, Mi-Kyung Ye, Jeong-Kyu Kim
A134 The study of clinical characteristics, lung function and bronchodilator responsiveness in infants with RSV bronchiolitis
Yong Feng, Yunxiao Shang
A135 GIS-based association between PM10 and allergic diseases in seoul: Implication for health and environmental policy
Sungchul Seo, Ji Tae Choung, Dohyeong Kim, Young Yoo, Hyunwook Lim
A136 The relationship between rhinovirus and recurrent wheezing
Wenjing Zhu, Chuanhe Liu, Li Sha, Li Chang, Min Zhao, Linqing Zhao, Yuan Qian, Yuzhi Chen
A137 Dominancy of Staphylcoccus Aureus in the Skin of Atopic Dermatitis Patients Compared to Healthy Subjects through Metagenomic Analysis
Min-Hye Kim, Young Joo Cho, Mina Rho, Jung-Won Kim, Yeon-Mi Kang, Kyung-Eun Yum, Hyeon-Il Choi, Jun-Pyo Choi, Han-Ki Park, Taek-Ki Min, Bok-Yang Pyun, Yoon-Keun Kim
A138 Micronized Cellulose Powder Reduces the Dose of Locally Applied Glucocorticoids in Patients with Allergic Rhinitis
Xueyan Wang
A139 New strategy for atopic dermatitis therapy with modulation of calcium ion channels
Woo Kyung Kim, Yu Ran Nam, Joo Hyun Nam
A140 Difference in the Systemic Bacterial Composition of Atopic Dermatitis Patients Compared to Healthy Subjects through Metagenomic Analysis of Urine
Jung-Won Kim, Min-Hye Kim, Mina Rho, Yeon-Mi Kang, Kyung-Eun Yum, Hyeon-Il Choi, Jun-Pyo Choi, Han-Ki Park, Taek-Ki Min, Young Joo Cho, Bok-Yang Pyun, Yoon-Keun Kim
A141 Occurrence and physiological function of immune complexes of food proteins and IgA in human saliva
Hiroshi Narita, Junko Hirose, Kumiko Kizu, Ayu Matsunaga
A142 Association between DNA hypomethylation at IL13 gene and allergic rhinitis in house dust mite-sensitized subjects
Jingyun Li, Yuan Zhang, Luo Zhang
A143 Effect of dietary methyl donors on asthma and atopy is modified by MTHFR polymorphism
Yean Jung Choi, Hye Lim Shin, Song-I Yang, So-Yeon Lee, Sung-Ok Kwon, Young-Ho Jung, Ji-Won Kwon, Hyung Young Kim, Ju-Hee Seo, Byoung-Ju Kim, Hyo-Bin Kim, Se-Young Oh, Ho-Jang Kwon, Eun Lee, Mi-Jin Kang, Soo-Jong Hong, Yun-Jeong Lee, Joonil Kim
A144 The effect of TSLP in a murine model of allergic asthma
Joon Young Choi, Ji Young Kang, Seok Chan Kim, Sei Won Kim, Seung Joon Kim, Young Kyoon Kim, Chin Kook Rhee, Hea Yon Lee, Hwa Young Lee, Sook Young Lee
A145 Evaluation of Aspirin Hypersensitivity in Chronic Rhinosinusitis Patients
Tae Kyung Koh, Sung Wan Kim, Kun Hee Lee, Chul Kwon, Joong-Saeng Jo, Sung-Hwa Dong, Young Seok Byun
A146 Chronic cough without wheezing in young children as a manifestation of chronic sinusitis
Charles Song
A147 Expression of muscarinic receptors and effect of tiotropium bromide on chronic asthma according to age in a murine model
Ji Young Kang, Hwa Young Lee, In Kyoung Kim, Sei Won Kim, Chin Kook Rhee, Seung Joon Kim, Seok Chan Kim, Sook Young Lee, Young Kyoon Kim, Soon Seog Kwon, Joon Young Choi
A148 Discrimination between non-eosinophilic and eosinophilic chronic rhinosinusitis with nasal polyps
Pona Park, Hong Ryul Jin, Dong-Kyu Kim, Dae Woo Kim
A149 Significant reduction in allergic features in the offspring of mice supplemented with specific non-digestible oligosaccharides during lactation
Astrid Hogenkamp
A150 Allergenicity assessment of hydrolysed infant formula; A multicenter comparison of a mouse model and a Guinea pig model for cow’s milk allergy
Leon Knippels, Betty C.a.m. Van Esch, Jolanda Van Bilsen, Prescilla V. Jeurink; Marjan Gros, Johan Garssen, Joost J Smit, Raymond H.H. Pieters
A151 Clinical significance between the allergic test and serum eosinophil cationic protein
Boo-Young Kim, Soo Whan Kim
A152 Hydroclorothiazide-induced acute non-cardiogenic pulmonary edema
Ramon Lleonart
A153 A Synbiotic Mixture of Scgos/Lcfos and Bifidobacterium Breve M-16V Is Able to Restore the Delayed Colonization of Bifidobacterium Observed in C-Section Delivered Infants
Christophe Lay, Kaouther Benamor, Chua Mei Chen, Jan Knol, Charmaine Chew, Voranush Chongsrisawat, Anne Goh, Wen Chin Chiang, Rajeshwar Rao, Surasith Chaithongwongwatthana, Nipon Khemapech
A154 Atopic characteristics of patients with asthma-COPD overlap syndrome
Ji Young Yhi, Sang-Heon Kim, Dong Won Park, Ji-Yong Moon, Tae Hyung Kim, Jang Won Sohn, Dong Ho Shin, Ho Joo Yoon, Seok Hyun Cho
A155 Perceptions and practices of severe asthma and asthma-COPD overlap syndrome among specialists: A questionnaire survey
Sang-Heon Kim, Ji-Yong Moon, Jae-Hyun Lee, Ga Young Ban, Sujeong Kim, Mi-Ae Kim, Joo-Hee Kim, Min-Hye Kim, Chan-Sun Park, Hyouk-Soo Kwon, Jae-Woo Kwon, Jae Woo Jung, Hye-Ryun Kang, Jong-Sook Park, Tae-Bum Kim, Heung Woo Park, You Sook Cho, Kwang-Ha Yoo, Yeon-Mok Oh
A156 A case of surgical diagnosed eosinophilic enteritis with intussusception in adult patient
Sang-Rok Lee
A157 Reference values of total IgE in estonian children
Kaja Julge, Maire Vasar, Tiia Voor, Tiina Rebane
A158 A case of eosinophilic granulomatosis with polyangiitis accompanied by rapidly progressive glomerulonephritis
Yu Jin Kim, Sang Min Lee, Shin Myung Kang, Sojeong Kim, Sun Young Kyung, Sung Hwan Jeong, Jeong-Woong Park, Hyunjung Hwang, Yong Han Seon, Sanghui Park, Sang Pyo Lee
A159 Associations Between Infectious Diseases and Urticaria
Marius Iordache
A160 Sleep in infants in korea – finding of bisq survey
Yeongsang Jeong, Sohee Eun, Byung Min Choi, Ji Tae Choung, Wonhee Seo
A161 Increased Expression of Filaggrin, TSLP, Periostin, IL13 and IL-33 in Nasal Polyps
Liang Zhang, Ruby Pawankar, Manabu Nonaka, Miyuki Hayashi, Shingo Yamanishi, Harumi Suzaki, Yasuhiko Itoh, So Watanabe, Hitome Kobayashi
A162 Asymptomatic bacteruria increases the risk of edematous attacks in patients with hereditary angioedema due to C1 inhibitor deficency (C1-INH-HAE)
Zsuzsanna Zotter, Henriette Farkas, Lilian Varga, Nora Veszeli, Eva Imreh, Gabor Kovacs, Marsel Nallbani
A163 Gastric Erosions Cause Spontaneous Urticaria Independent of Helicobacter Pylori
Semen Zheleznov, Galina Urzhumtseva, Natalia Petrova, Zhanna Sarsaniia, Nikolai Didkovskii, Torsten Zuberbier
A164 The Effect of G2 Vaccine on the Gene Expression NKG2D and Receptor Presenting on the Surface of NK Cells in Peripheral Blood
Nader Dashti Gerdabi, Ali Khodadadi, Zahra Abdoli, Mehri Ghafourian, Mohammad Ali Assarehzadegan, Khodayar Ghorban
A165 Ethnic differences in lifetime prevalence and indoor environmental factors for childhood eczema
Hyo-Bin Kim, Hui Zhou, Jeong Hee Kim, Rima Habre, Theresa Bastain, Frank Gilliland
A166 A case of methazolamide-induced toxic epidermal necrolysis
Jong-Wook Bae, Kyu-Hyung Han, Young-Koo Jee, Misoo Choi, Seung-Phil Hong, Seung-Hyun Kim
A167 Inflammatory responses of human adipose-tissue derived stem cells to LPS and nanoparticles
Hee-Kyoo Kim, Gil-Soon Choi, Jeonghoon Heo, Young-Ho Kim, Eun-Kee Park
A168 Analysis of 71 Cashew Nut Oral Challenge Tests
Takashi Inoue, Kiyotake Ogura, Noriyuki Yanagida, Hirotoshi Unno, Kenichi Nagakura, Tetsuharu Manabe, Tomoyuki Asaumi, Sakura Sato, Yu Okada, Motohiro Ebisawa
A169 Fungal sensitization is associated with asthma exacerbation
Min-Gu Kim, You Sook Cho, Tae-Bum Kim, Hee-Bom Moon, Jung-Hyun Kim, Hyo-Jung Kim, So-Young Park, Bomi Seo, Hyouk-Soo Kwon, Jaemoon Lee, Taehoon Lee
A170 Individual therapeutic patient education and consultation in children with atopic dermatitis
Hye-Soo Yoo, Jieun Kim, Inok Kim, Haejin Kim, Younhee Chang, Hae-Sim Park, Sooyoung Lee
A171 Utility of Alpha-Lactalbumin Specific IgE Levels Using Immulite 2000 3gAllergy in Predicting Clinical Severity of Milk Allergy
Kazuyo Kuzume, Munemitsu Koizumi, Koji Nishimura, Michiko Okamoto
A172 Isoniazid/rifampicin-specific t-cell responses in patients with anti-tuberculosis –induced dress syndrome
Seung-Hyun Kim, Young Min Ye, Gyu Young Hur, Hae-Sim Park, Sang-Heon Kim, Young-Koo Jee
A173 Genetic biomarkers associated with aspirin-exacerbated respiratory disease (AERD) phenotype based on genome-wide association study
Seung-Hyun Kim, Hyunna Choi, Young Min Ye, Hae-Sim Park
A174 Assessment of ORAL drug provocation test in the diagnosis of NON-steroidal ANTI-inflammatory drugs hypersensitivity
Bui VAN Khanh, Hieu Chi Chu, Nguyen Nhu Nguyet, Nguyen Hoang Phuong
A175 Korean treatment guideline of atopic dermatitis
Joo Young Roh, Hyun Jeong Kim, Jung Eun Kim, Bark-Lynn Lew, Kyung Ho Lee, Seung-Phil Hong, Yong Hyun Jang, Kui Young Park, Seong Jun Seo, Jung Min Bae, Eung Ho Choi, Ki Beom Suhr, Seung Chul Lee, Hyun-Chang Ko, Young Lip Park, Sang Wook Son, Young Jun Seo, Yang Won Lee, Sang Hyun Cho, Chun Wook Park
A176 Systemic side reaction of subcutaneous immunotherapy(SCIT) for perennial allergic rhinitis
Kun Hee Lee, Sung Wan Kim
A177 Clinical baseline characteristics of Asian patients suffering from refractory chronic spontaneous urticaria (CSU) in three phase 3 omalizumab clinical trials
Chia-Yu CHU, Derrick Aw, Young-Min Ye, Giovanni Bader, Fabrizio Dolfi, Nathalie Oliveira
A178 A metagenomic approach through t-RFLP to the microbiome of asthma
Jae Chol Choi, Jae Woo Jung, Hye-Ryun Kang, Kijeong Kim, Byoung Whui Choi
A179 Clinical characteristics and ten-year trend of peripheral blood eosinophilia among health screening program recipients at a tertiary hospital of South Korea
Jong Wook Shin, Jae Woo Jung, Jae Chol Choi, In Won Park, Byoung Whui Choi, Jae Yeol Kim
A180 The prevalence of toxocariasis and diagnostic value of serologic tests in asymptomatic Korean adults
Jin-Young Lee, Kyoung Won Ha, Yun-Jin Jeung, Sehyo Yune, Byung-Jae Lee, Dong-Chull Choi, Mi-Jung Oh, Young Hee Lim
A181 Cutaneous Drug Hypersensitivity Reaction in Korean Children: An Analysis of KAERS Database on 2012-2013
Eui Jun Lee, Dongin Suh, Sung-Il Woo, Hwa Jin Cho, Eun Hee Chung, Soo Youn Chung
A182 Comparison of clinical characteristics, quality of life and sleep in patients with allergic rhinitis when categorised as “sneezers and runners” and “blockers”
Kamal Gera, Ashok Shah
A183 Role of s-nitrosoglutathione reductase (GSNOR) in the murine strain differences of airway hyperresponsiveness
Jin-Young Lee, Kyoung Won Ha, Mi-Jung Oh, Young Hee Lim, Sehyo Yune, Jae-Won Paeng, Mi-Jin Jang, Byung-Jae Lee, Dong-Chull Choi
A184 Protection from airway bronchoconstriction by gsno
Jin-Young Lee, Mi-Jin Jang, Jae-Won Paeng, Yun-Jin Jeung, Young Hee Lim, Mi-Jung Oh, Kyoung Won Ha, Byung-Jae Lee, Dong-Chull Choi, Sehyo Yune
A185 Does EIA-targeted asthma treatment improve daily physical activity of children?
Takahiro Ito
A186 Wheezing as a clue to the diagnosis of cough variant asthma and nonasthmatic eosinophilic bronchitis
Jihye Kim, Jin-Young Lee, Sehyo Yune, Byung-Jae Lee, Dong-Chull Choi, Mi-Jin Jang, Jae-Won Paeng, Young Eun Kim, Young Nam Kim, Yongseok Lee
A187 Antagonism of microRNA-21 suppressed the airway inflammation in a mouse model of bronchial asthma
Hwa Young Lee, Sook Young Lee, Soon Seog Kwon, Young Kyoon Kim, Chin Kook Rhee, Sei Won Kim, Hea Yon Lee, Joon Young Choi, In Kyoung Kim
A188 Chlorhexidine anaphylaxis: A report of two cases
Jose Antonio Navarro, Maria Ascension Aranzabal, Alejandro Joral, Susana Lizarza, Miguel Echenagusia, EVA Maria Lasa
A189 Effects of Particulate Matter on Respiratory Allergic Diseases Considering Meteorological Factors in Busan, Korea
Eun-Jung Jo, Sun-Mi Jang, Seung-Eon Song, Hae-Jung Na, Chang-Hoon Kim, Woo-Seop Lee, Hye-Kyung Park
A190 Clinical characteristics of neutrophilic asthma
Sachiko Miyauchi, Yoshitaka Uchida, Tomoyuki Soma, Susumu Yamazaki, Toru Noguchi, Takehito Kobayashi, Kazuyuki Nakagome, Makoto Nagata
A191 Current Practice of Infants and Children with Acute Urticaria at a Single Wide Regional Emergency Medical Center
Hea Lin Oh, Do Kyun Kim, Dongin Suh, Young Yull Koh
A192 Discordance between sputum eosinophilia and exhaled nitric oxide
Sehyo Yune, Jin-Young Lee, Byung-Jae Lee, Dong-Chull Choi, Jae-Won Paeng, Mi-Jin Jang, Jihye Kim, Young Nam Kim
A193 Association between genetic polymorphisms of costimulatory molecules and antituberculosis drugs induced hepatitis
Sang-Heon Kim, Sang-Hoon Kim, Jang Won Sohn, Ho Joo Yoon, Dong Ho Shin, Jae Hyung Lee, Byoung Hoon Lee, Youn-Seup Kim, Jae-Seuk Park, Young-Koo Jee
A194 The prevalence of gastroesophageal reflux disease in chronic unexplained cough
Sehyo Yune, Jin-Young Lee, Jae-Won Paeng, Mi-Jin Jang, Dong-Chull Choi, Byung-Jae Lee, Yongseok Lee, Young Eun Kim
A195 Risk Factors of Allergic Rhinitis in Preschool Children and Clinical Utility of Feno
Jisun Yoon
A196 Relationship between serum 25-hydroxyvitamin d and asthma exacerbation severity in children
Yong Feng, Li Zhang, Xuxu Cai
A197 Usefulness of Specific IgE Antibody Levels to Wheat, Gluten and Ï-5 Gliadin for Wheat Allergy in Korean Children
Jong-Seo Yoon, Kyunguk Jeong, Hye-Soo Yoo, Sooyoung Lee, Sooyoung Lee
A198 Neutralization of stratum corneum accelerates the progress from atopic dermatitis to asthma-like lesion in flaky tail mice treated by house dust mite allergen
Hae-Jin Lee, Noo Ri Lee, Bo-Kyung Kim, Minyoung Jung, Dong Hye Kim, Catharina S. Moniaga, Kenji Kabashima, Eung Ho Choi
A199 Trends in oral food challenges in Japan: A six-year prospective study
Noriyuki Yanagida, Sakura Sato, Chizuko Sugizaki, Motohiro Ebisawa
A200 The Gut Microbiome in the Food Allergic Host
Jamie Kiehm, Punita Ponda, Sherry Farzan, Jared Weiss, Claudia Elera, Catherine Destio, Cristina Sison, Annette Lee
A201 Cord blood cytokines and maternal environmental exposure during pregnancy
Soo Hyun Ri, Chang Hoon Lim
A202 Rupatadine pharmacokinetics in Japanese healthy volunteers after single and repeated oral doses of 10, 20 and 40 mg
Iñaki Izquierdo Pulido, Jorg Taubel, Georg Ferber, Eva Santamaria Masdeu
A203 A safe and effective method to desensitize patients with wheat allergy
Alireza Khayatzadeh, Masoud Movahedi, Motohiro Ebisawa, Mohammad Gharagozlou
A204 RNA Binding Protein Hur Regulates CD4+ T Cell Differentiation and Is Required for Allergic Airway Inflammation and Normal IL-2 Homeostasis
Ulus Atasoy, Patsharaporn Techasintana, Matt Gubin, Jacqueline Glascock, Suzanne Ridenhour, Joseph Magee
A205 Time Trends in the Epidemiology of Recurrent Wheezing in Infants from South America
Nelson Rosario Filho; Herberto Jose Chong Neto, Gustavo Falbo Wandalsen, Ana Caroline Dela Bianca, Carolina Aranda, Dirceu Sole, Javier Mallol, Luis Garcia-Marcos, Luis Garcia-Marcos
A206 Successful Cyclophosphamide Desensitization in a Pediatric Patient with Systemic Lupus Erythematosus
Jennifer Toh, Yoomie Lee, Joyce Huang, Elina Jerschow, Jenny Shliozberg
A207 The Fatty Acid Binding Protein Der p 13 Is a Minor House Dust Mite Allergen Able to Activate Innate Immunity
Pattraporn Satitsuksanoa, Narissara Suratannon, Jongkonnee Wongpiyabovorn, Pantipa Chatchatee, Kiat Ruxrungtham, Alain Jacquet
A208 Epidemiology of Stevens-Johnson Syndrome and Toxic Epidemal Necrolysis: An Administrative Database Study
Min Suk Yang; Jin Yong Lee, Ja Yeun Kim, Han-Ki Park, Ju-Young Kim, Woo-Jung Song, Hye-Ryun Kang, Heung Woo Park, Yoon-Seok Chang, Sang-Heon Cho, Kyung-up Min, Chang-Han Park, Suk-Il Chang, Sook-Hee Song
A209 Regional Differences of Vitamin D and Food-Induced Anaphylaxis in Korea
Si-Heon Kim, Gil-Soon Choi, Su-Chin Kim, Ji Hye Kim, Ga Young Ban, Yoo Seob Shin, Hae-Sim Park, Young Min Ye
A210 Triggering Factors of Atopic Dermatitis By Severity
Yoon Ha Hwang
A211 Clinical Features of Adverse Drug Reactions of Monoclonal Antibodies in Korea
Da Woon Sim, Kyung Hee Park, Kyung Hee Park, Hye Jung Park, Hye Jung Park, Jung-Won Park, Jung-Won Park, Jae-Hyun Lee, Jae-Hyun Lee
A212 Food Allergy with Eczema Is Associated with Reduced Growth in the First Four Years of Life
Katrina Allen, Cara Beck, Jennifer Koplin, Melanie Matheson, Mimi Tang, Anne-Louise Ponsonby, Lyle Gurrin, Shyamali Dharmage, Melissa Wake, Vicki Mcwilliam
A213 The Preliminary Study on Clinical Efficacy and Impact Factors of One Year’s Dust Mite Specific Immunotherapy in Allergic Asthma and Rhinitis Children Sensitized to Dust Mite
Xiaoying Liu, Jing Wang, Li Xiang, Qun Wang
A214 Lipopolysaccharide Signaling through Toll- like Receptor 4 Could be Augmented By Dermatophagoides Farinae in the Human Middle Ear Epithelial Cell
Ji-Eun Lee, Dong-Young Kim, Chae-Seo Rhee, Chae-Seo Rhee
A215 Drug Allergy in Pregnant Adolescents: Relation with Familial and Personal Atopy, and Substances Use
Francisco Vazquez-Nava
A216 Patients and Physicians Concept of Well-Controlled Asthma: Findings from Realise Asia
Sang-Heon Cho, Jaewon Jeong, Diahn-Warng Perng, David Price, Glenn Neira, Jiangtao Lin
A217 The Role of Vasoactive Intestinal Peptide in the Pathophysiology of Acute Asthma
Olga Semernik
A218 Comparison of Serum Cytokine Levels According to the Severity in Atopic Dermatitis
Ha-Su Kim, Jin-a Jung, Ji-in Jung
A219 The Different Influence on the Regulatory T Cell Response Between Subcutanous Immnuotherapy(SCIT) and Sublingual Immunotherapy(SLIT) in Children with Asthma
Qing Miao, Li Xiang
A220 Asthma State of Affairs in Asia: Seeing through Physicians’ and Patients’ Lenses
Sang-Heon Cho, Jaewon Jeong, Diahn-Warng Perng, Jiangtao Lin, David Price
A221 Identification of Aspirin Exacerbated Respiratory Disease (AERD) Phenotypes Using Two Step Cluster Analysis
Hyun Young Lee, Hae-Sim Park, Young Min Ye, Su Chin Kim
A222 Dusty Air Pollution Are Associated with an Increase Risk of Allergic Diseases in General Population
Shokrollah Farrokhi, Mohammadkazem Gheiby
A223 A Genome-Wide Association Study of Antituberculosis Drugs-Induced Hepatitis
Sang-Heon Kim; Heung Woo Park, Sang-Hoon Kim, Young-Koo Jee
A224 The Role of peroxiredoxin6 of Bronchial Epithelial Cells in Regulating Mitochondrial Function Under Oxidative Stress By Translocation to Outside Mitochondrial Membrane
Sunjoo Park, Keun Ai Moon, Hyouk-Soo Kwon, Tae-Bum Kim, You Sook Cho, Hee-Bom Moon, Kyoung Young Lee, Gyong Hwa Hong, Eun Hee Ha
A225 Toxic and Adjuvant Effects of 3 Types of Silica Nanoparticles on Airway System
Heejae Han, Hye Jung Park, Yoon Hee Park, Yoon-Jo Kim, Kangtaek Lee, Jung-Won Park, Jae-Hyun Lee
A226 Procedure for Diagnostic and Selection of Immunotherapy Method for Children with Different Immunopathogenetic Phenotypes of Atopic Dermatitis
Tatiana Slavyanskaya, Vladislava Derkach
A227 Prediction of the Success of Our Desensitization Protocol with Symptoms and Results of a Skin Prick Test in Patients with Hypersensitivity to Platinum-Based Chemotherapy
Hye Jung Park, Chein-Soo Hong, Jae-Hyun Lee, Jae-Hyun Lee, Sungryeol KIM, Sungryeol KIM, Kyung Hee Park, Kyung Hee Park, Choong-Kun Lee, Beodeul Kang, Seung-Hoon Beom, Sang Joon Shin, Minku Jung, Jung-Won Park, Jung-Won Park
A228 Anti-Allergic Effect of Intralymphatic Injection of OVA-Flagelin Mixture in Mouse Model of Allergic Rhinitis
Eun-Hee Kim, Ji-Hye Kim, Ji-Hun Mo, Young-Jun Chung
A229 Serum Periostin Level Is Higher in Respiratory Type of NSAID Hypersensitivity Than Cutaneous Type
Mi-Ae Kim, Hae-Sim Park, Moon Gyeong Yoon, Young-Soo Lee, Ji Hye Kim, Ga Young Ban, Hye-Soo Yoo, Yoo Seob Shin, Young Min Ye, Dong-Ho Nahm
A230 A Retrospective Analysis of Allergy Blood Testing in Beijing Children’s Hospital in the Year of 2013: A Single-Center Research
Qing Miao, Li Xiang
A231 Role of Nrf2 in the Allergic Airway Inflammation Differ Between BALB/c and C57BL/6 Mice
Ying-Ji Li, Takako Shimizu, Hirofumi Inagaki, Yukiyo Hirata, Hajime Takizawa, Arata Azuma, Masayuki Yamamoto, Tomoyuki Kawada
A232 Effect of Human Mesenchymal Stem Cell on Neutrophilic Asthma Model
Min-Gu Kim, Gyong Hwa Hong, Kyoung Young Lee, Eun Hee Ha, Keun Ai Moon, Sunjoo Park, Hyouk-Soo Kwon, Tae-Bum Kim, Hee-Bom Moon, You Sook Cho, Jung-Hyun Kim, Hyo-Jung Kim, So-Young Park, Bomi Seo
A233 Immunomodulatory Effect of Tonsil Derived Mesenchymal Stem Cells in a Mouse Model of Allergic Rhinitis
Ji-Hye Kim, Ramachandran Samivel, Eun-Hee Kim, Young-Jun Chung, Ji-Hun Mo
A234 Alternative Therapy Such As Yoga May be a Low Cost Tool for Improving the Quality of Life of Patient’s with Allergic Rhinitis and Asthma
Soumya M. S., G. Inbaraj, R. Chellaa, Ruby Pawankar
A235 Substantial Impairment of the Quality of Life in Adult Patients with Chronic Urticaria
Wonsun Choi, Hae-Sim Park, Young Min Ye, Ji Hye Kim, Ga Young Ban, Yoo-Seob Shin
A236 Dietary Galacto-Oligosaccharides Reduce Airway Eosinophilia and Enhance the Th2 Suppressive Effect of Budesonide in House Dust Mite-Induced Asthma in Mice
Saskia Braber, Kim Verheijden, Aletta Kraneveld, Johan Garssen, Linette Willemsen, Gert Folkerts
A237 Production and Characterization of Recombinant Periplaneta americana Allergens for Component Resolved Diagnosis
Stephanie Eichhorn, Fatima Ferreira, Isabel Pablos, Bianca Kastner, Bettina Schweidler, Sabrina Wildner, Peter Briza, Jung-Won Park, Naveen Arora, Stefan Vieths, Gabriele Gadermaier
A238 Assessment of Characteristics of Itch in Patients with Hand Eczema
Sung-Min Park, Won-Ku Lee, Jeong-Min Kim, Gun-Wook Kim, Je-Ho Mun, Hoon-Soo Kim, Margaret Song, Hyun-Chang Ko, Moon-Bum Kim, Byung Soo Kim
A239 The Hidden Culprit: A Case of Repeated Anaphylaxis from Cremophor Hypersensitivity.
Young Nam Kim, Sehyo Yune, Jin-Young Lee, Jihye Kim, Young Eun Kim, Jae-Won Paeng, Mi-Jin Jang, Dong-Chull Choi, Byung-Jae Lee, Yongseok Lee
A240 Spectrum of Anaphylaxis in Children and Adults at Emergency Departments in Singapore
Si Hui Goh, Bee Wah Lee, Jian Yi Soh
A241 Improved Quality of Life through an Integrated Health Care Service for Children with Atopic Dermatitis
Hyungoo Kang; Hyunhee Kim; Hye-Yung Yum
A242 Criteria Combining Autologous Serum Skin Test and Clusterin for Predicting Antihistamine-Refractoriness in Patients with Chronic Spontaneous Urticaria
Young Min Ye; Hae-Sim Park; Ga-Young Ban; Ji Hye Kim; Yoo Seob Shin
A243 Urinary Leukotriene E4 Levels in Wheezing Infants
Takumi Takizawa, Masahiko Tabata, Akira Aizawa, Hisako Yagi, Yutaka Nishida, Hirokazu Arakawa, Akihiro Morikawa, Solongo Orosoo
A244 Allergic Sensitization to Whey in Mice Is Facilitated By the Mycotoxin Deoxynivalenol (DON)
Saskia Braber, Marianne Bol-Schoenmakers, Peyman Akbari, Prescilla V. Jeurink, Prescilla V. Jeurink, Priscilla De Graaff, Joost J. Smit, Betty C. A. M. Van Esch, Johan Garssen, Johan Garssen, Johanna Fink-Gremmels, Raymond H. H. Pieters
A245 How to Define Chronic Cough: Based on a Systematic Review of the Epidemiological Literature
Gun-Woo Kim, Eun-Jung Jo, Sujeong Kim, Woo-Jung Song, Yoon-Seok Chang, Shoaib Faruqi, Ju-Young Kim, Mingyu Kang, Min-Hye Kim, Jana Plevkova, Heung Woo Park, Sang-Heon Cho, Alyn Morice, So-Hee Lee, Sun-Sin Kim, Seoung-Eun Lee
A246 Asko Study: Comparison of Behavior and Habits in Diagnosis and Treatment of Adult Asthma and COPD Patients
Bilun Gemicioglu, Zeynep Misirligil, Arif Hikmet Cimrin, Hakan Gunen, Tevfik Ozlu, Aykut Cilli, Levent Akyildiz, Hasan Bayram, Esra Uzaslan, Oznur Abadoglu, Mecit Suerdem
A247 Changes in Pulmonary Function in the Treatment of Obesity in Children
Keigo Kainuma
A248 Changes of Feno and Nasal Feno Levels after Treatment in Pediatric Allergic Rhinitis
Hyun-a Kim, Ha-Su Kim, Woo Yong Bae, Jin-a Jung
A249 Prevalence of Vitamin D Deficiency in Exclusively Breastfed Infants in Kenya
Rose Kamenwa, William Macharia, Nusrat Said
A250 In-Vitro Screening of Atopy in the Indian Population: Are Current Methods Adequate, Keeping Local IgE Seroprevalence for Common Food & Inhalant Allergens in Mind?
Vidya Nerurkar, Meenal Patel, Simi Bhatia
A251 Usefulness of House Dust Mites Nasal Provocation Test in Asthma
Inseon S Choi, Soo-Jeong Kim, Joo-Min Won, Myeong-Soo Park
A252 Biomarker-Based Treatment Option for Preschool Children with Recurrent Wheeze
Mizuho Nagao
A253 Anti-Tuberculosis Drugs-Induced Liver Injury in Patients with Connective Tissue Diseases
Dong Won Park, Jang Won Sohn, Ji Young Yhi, Ji-Yong Moon, Sang-Heon Kim, Tae Hyung Kim, Dong Ho Shin, Ho Joo Yoon
A254 Ocular Symptoms of Cedar Pollinosis in Otolaryngology Patients
Yukiyoshi Hyo
A255 The Clinical Characteristics of Adverse Drug Reactions Reported in a Regional University Hospital for 6 Years and the Suggestions for the Reporting System
Jaechun Lee, Su Hee Kim, Eunkyoung Lee
A256 Changes in Skin Prick Test Results over 3 Years in School-Aged Children
Hahn Jin Jung, Jaehyun Lim, Seung-No Hong, Doo Hee Han, Chae-Seo Rhee
A257 The Analysis of Risk Factors and Features of Food Allergy in Korean Children: Nationwide Cross-Sectional Survey
Kun Song Lee
A258 A Sequential Indirect-Direct Bronchial Provocation Test for Diagnosis of Asthma: A Pilot Study
Jaechun Lee, Sun Young Yang, Mi Young Ahn, Jong Hoo Lee, Jasmina Golez
A259 Association of VDR and CYP2R1 Polymorphisms with Persistent Allergic Rhinitis in a Han Chinese Population
Hui-Qin Tian, Lei Cheng, Xin-Yuan Chen
A260 Associations of Metabolic Syndrome with Asthma and Atopy in Korean Adults
Ji-Yong Moon, Sang-Heon Kim, Tae Hyung Kim, Ji Young Yhi, Ho Joo Yoon, Jang Won Sohn, Dong Ho Shin, Dong Won Park
A261 Clinical Manifestation and Treatment Outcome of Eosinophilic Gastroenteritis in Korean Children
Won Im Cho, Jong Sub Choi, Dongin Suh, Gyeong Hoon Kang, Jin Soo Moon, Jae Sung Ko, Kyung Jae Lee, Shin Jie Choi
A262 The Sensitization Model and Correlation of Bermuda and Timothy Grass Pollen Allergen in Allergic Patients in Southern China
Wenting Luo, Baoqing Sun
A263 A Pilot Study on the Outcomes of Respiratory Allergic Diseases at Pre-School Age in Chinese Infants with Atopic Dermatitis
Qi Gao, Li Xiang, Kunling Shen
A264 Activation of Toll like Receptor 1 and 6 By House Dust Mite Enhances the Expression of Tight Junction Protein in Epidermal Keratinocytes
Yong Hyun Jang
A265 Pollen Exposure in a Mobile Exposure Chamber: Comparing Real-Life Symptoms with Exposure Symptoms
Karl-Christian Bergmann, Torsten Sehlinger, Georg Bölke, Uwe Berger, Torsten Zuberbier
A266 Retrospective Analysis of the Incidence of Allergy in Patients with Contact Eczema
Joanna Kolodziejczyk, Milena Wojciechowska, Anna Hnatyszyn-Dzikowska, Micha Chojnacki, Zbigniew Bartuzi
A267 Effect of Fungal Sensitization in Patients with Severe Asthma
Katsunori Masaki, Koichi Fukunaga, Takashi Kamatani, Kengo Ohtsuka, Takae Tanosaki, Masako Matsusaka, Takao Mochimaru, Hiroki Kabata, Soichiro Ueda, Yusuke Suzuki, Katsuhiko Kamei, Koichiro Asano, Tomoko Betsuyaku
A268 SCIg Patient Preference Pump Versus Push
Karlee Trafford
A269 Fixed Drug Eruption Induced By Ornidazole and Diclofenac
Ismet Bulut, Zeynep Ferhan Ozseker
A270 Transepidermal Water Loss Measurement during Infancy Can Predict the Subsequent Development of Atopic Dermatitis
Kenta Horimukai, Hideaki Morita, Masami Narita, Hironori Niizeki, Kenji Matsumoto, Yukihiro Ohya, Hirohisa Saito, Shigenori Kabashima, Mai Kondo, Eisuke Inoue
A271 Inhalant Allergens on Soft Toys: A Literature Review
Robert Siebers, Francis FS Wu
A272 Fractional Exhaled Nitric Oxide in Elderly Asthmatics
Robert Siebers, Francis FS Wu, Ming-Hui Ting, Hung-En Laio, Tsung-Huai Kuo, Pei-Yuan Lee
A273 Dye and Preservative Challenge in Meal-Associated Urticaria and Angioedema: A Low-Yield Diagnostic Maneuver
Daniel Eugene Maddox
A274 The Changes of Allergic Sensitization with Age in Children with Allergic Rhinitis
Gwanghui RyuHyo Yeol Kim, Hun-Jong Dhong, Sang Duk Hong, Seung-Kyu Chung
A275 Component-Specific IgE and IgG4 Levels in Milk Allergy Children Tolerated Baked Milk Products
Osamu Higuchi, Yu-Ichi Adachi, Toshiko Itazawa, Yoko Adachi, Miki Hamamichi, Motokazu Nakabayashi, Yasunori Ito, Takuya Wada, Gyoukei Murakami, Miki Takao, Junko Yamamoto
A276 Serum Surfactant Protein(SP)-D Level: A Potential Biomarker for Aspirin-Exacerbated Respiratory Disease
Hyun Jung Jin, Moon Gyeong Yoon, Young Min Ye, Yoo-Seob Shin, Seung-Hyun Kim, Hae-Sim Park
A277 Clinical Characteristics of Anaphylaxis in Korean Children
Taek-Ki Min, Bok-Yang Pyun, So-Yeon Lee, Hyun Hee Kim, Gwang-Cheon Jang, Jinho Yu, Dongin Suh, Sooyoung Lee, Yong Mean Park, Jeong Hee Kim, Hye-Yung Yum, Kyung Won Kim, Hyeon-Jong Yang, Kangmo Ahn, Ji-Won Kwon, Myung Hyun Sohn, Hae Ran Lee, Jung Hyun Kwon, Kyu-Earn Kim, Soo-Jong Hong
A278 Immunological Changes Induced By Intramuscular Injections of Autolologous Immunoglobulin in Patients with Severe Atopic Dermatitis
Su-Mi Cho
A279 Identification of Subtypes in Subjects with Mild to Moderate Airflow Limitation and Their Clinical and Socioeconomic Implications
Jin Hwa Lee, Chin Kook Rhee, Hye Yun Park, Woo Jin Kim, Yong Bum Park, Kwang-Ha Yoo
A280 Cephalosporin-Induced Dress (Drug Rash with Eosinophilia and Systemic Symptoms) Syndrome in a 7-Year-Old Boy
Heejeong Kang, Hyeon-Jong Yang, Taek-Ki Min, Bok-Yang Pyun
A281 Maternal Depression Is Associated with Children’s Asthma : An Analysis of the Fifth Korea National Health and Nutrition Examination Survey (2010-2012)
Lee Ju Suk, Cheol Hong Kim
A282 Increased Length of Hospitalization Associated with Infiltration on Chest Radiography in Pediatric Asthma Patients
Jung Hyun Kwon, Sang Hyun Lee, Wonhee Seo
A283 A Case of 16-Year-Old Boy with Smoking-Induced Acute Eosinophilic Pneumonia
Kang-in Kim, Young Cheon Park, Hyeon-Jong Yang, Taek-Ki Min; Bok-Yang Pyun
A284 A Case of Pranlukast Induced Anaphylactic Shock
Sujeong Kim, Sun Jin, Jong-Myung Lee, Hye-Jin Jung, Jung-Wha Park
A285 Comparison of Asthma-Related Outcomes Between Metabolically Healthy Obese and Metabolically Unhealthy Obese Asthma Patients
Hyo-Jung Kim, Tae-Bum Kim, You Sook Cho, Hee-Bom Moon, Hyouk-Soo Kwon, So Young Park, So-Young Park, Jung-Hyun Kim, Bomi Seo, Min-Gu Kim, Youn Yee Kim
A286 Rick Factors Associated with Longer Length of Stay in Infants Hospitalized with Respiratory Syncytial Virus Bronchiolitis
Yena Lee, Taek-Ki Min, Hyeon-Jong Yang, Bok-Yang Pyun, Suk Hee Han, Suyeon Park, Jeongho Lee, Won-Ho Hahn
A287 Urinary Excretion of 9α, 11Î2-Prostaglandin F2 and Leukotriene E4 in Patients with Exercise-Induced Bronchoconstriction
Youhoon Jeon, Joo-Hee Kim, Tae-Rim Shin, Cheol-Hong Kim, In-Gyu Hyun, Jeong-Hee Choi
A288 The Aeroallergen Sensitization Pattern and Effect on Airway Hyperresponsiveness in Busan, Korea
Sun-Mi Jang, Hae-Jung Na, Seung-Eon Song, Hye-Kyung Park, Eun-Jung Jo
A289 Multicenter Questionnaires on Current Management of Atopic Dermatitis Among Korean Patients and Caregivers
Dong Hun Lee, Jin-Young Lee, Yang Park, Jae-Won Oh, Mi Hee Lee, Soo-Jong Hong, Soo-Jong Hong, So-Yeon Lee, Joon Soo Park, Dong-Ho Nahm, Hye-Yung Yum, Hye-Yung Yum
A290 Der p 1, Der p 2 and Der p 10 IgE Reactivities in Allergic Rhinitis Patients in Korea
Kyu Young, Dong-Young Kim
A291 De-Labeling Beta-Lactam Hypersensitivity: An Experience from a Tertiary Care Hospital in Thailand
Sirinoot Palapinyo; Jettanong Klaewsongkram
A292 Sonic Hedgehog Signaling: Evidence for Its Protective Role in Endotoxin Induced Acute Lung Injury Mouse Model
Xing Chen, Yuting Jin, Xiaoming Hou, Fengqin Liu, Chunyan Guo, Yulin Wang
A293 Analyses of the Factors behind the Negative Attitudes Toward the Administration of Adrenaline Auto-Injectors in School Settings
Ikuo Okafuji, Yuya Tanaka, Shegeyuki Narabayashi, Satoru Tsuruta
A294 Low Vitamin D Levels Are Related to High House Dust Mite Sensitization in Patients with Severe Atopic Dermatitis
Yong Hyun Jang
A295 Appendicular Skeletal Muscle Mass Index: A Potential Predictor of Skeletal Muscle Abnormality According to the Severity Airflow Limitation of COPD
Jun-Hong Ahn, Dong-Won Lee, Jin Hong Chung, Hyun Jung Jin, Min-Su Sohn
A296 Etiology and Clinical Feature of Oral Allergy Syndrome in Children
Young a Park, Kyunguk Jeong, Yoon Hee Kim, In Suk Sol, Seo Hee Yoon, Kyung Won Kim, Myung Hyun Sohn, Kyu-Earn Kim, Sooyoung Lee
A297 Traffic-Related Pollution Levels and Poorly Controlled Asthma in Adults
Ho Kim, Ja Yeun Kim
A298 Anaphylaxis in Korean Children, 2009-2013 : Triggers of Anaphylaxis By Age Groups
So-Yeon Lee, Taek-Ki Min, Tae-Won Song, Kangmo Ahn, Jihyun Kim, Gwang-Cheon Jang, Hyeon-Jong Yang, Bok-Yang Pyun, Ji-Won Kwon, Myung Hyun Sohn, Kyu-Earn Kim, Jinho Yu, Soo-Jong Hong, Jung-Hyun Kwon, Sung-Won Kim, Sooyoung Lee, Woo Kyung Kim, Hyung Young Kim, Hye-Young Kim, Youhoon Jeon
A299 Maternal Allergy Is Associated with Acute Bronchiolitis Severity in Infant
Chang Hoon Lim, Yeongsang Jeong, Su Jung Kim
A300 Evaluation of Inflammatory Mediator Profiles in Sputum of Asthmatics As an Endotype for Refractory Asthma
Hun Soo Chang, Jeong-Seok Heo, Da-Jeong Bae, Jong-Uk Lee, Ji-Na Kim, Chang-Gi Min, Hyun Ji Song, Jong-Sook Park, Soo Hyun Kim, Choon-Sik Park
A301 Autophagy Is Associated with the Severity of Asthma in an Ovalbumin-Specific Mouse Model of Allergic Asthma
Jing-Nan Liu, Youngwoo Choi, Yoo Seob Shin, Hae-Sim Park
A302 Interleukin-9 and Interleukin-33 Levels in Children with Asthma
Nima Rezaei, Sedigheh Bahrami Mahneh, Arezou Rezaei, Maryam Sadr, Masoud Movahedi
A303 Pediatric Anaphylaxis at a University Hospital in Cheonan, Korea, 2013~2014
Jun Seak Gang, Joon Soo Park, Seung Soo Kim, Hyun Ho Bang, Kyeong Bae Park, Hye Sun Kim, Tae Ho Kim, Young Hwangbo, Hyun Jung Lee, Gyeong Hee Yoo, Young Chang Kim
A304 Initial Antigen-Specific IgE Levels Predict Clinical Outcome of Rush Oral Immunotherapy for Food Anaphylaxis
Sakura Sato, Noriyuki Yanagida, Motohiro Ebisawa
A305 ABCC4 gene Polymorphism Is Associated with High Periostin Levels in Asthmatic Patients
Sailesh Palikhe, Hae-Sim Park, Seung-Hyun Kim, Ri-Yeon Kim, Eun-Mi Yang
A306 The Role of Clinical Phenotype and Allergen Sensitization at 2 Years As Predictors of Atopic Disorders at 5 Years
Li Yuan Gabriella Nadine Lee, Marion Aw, Marion Aw, Bee Wah Lee, Bee Wah Lee, Evelyn Xiu Ling Loo, Yiong Huak Chan, Lynette Shek, Lynette Shek, I-Chun Kuo, I-Chun Kuo, Phaik Ling Quah, Phaik Ling Quah, Genevieve Llanora, Gerez Irvin
A307 The Effect of Korean Red Ginseng (KRG) on Rhinovirus Infection in Human Nasal Epithelial Cells
Joo Hyun Jung, Il Gyu Kang, Seon Tae Kim, Hyoungmin Park
A308 The Effect of Korean Red Ginseng on the Symptoms and Allergic Inflammation in Patients with Allergic Rhinitis
Seon Tae Kim, Joo Hyun Jung, Il Gyu Kang, Hyoungmin Park, Kwang-Pil Ko
A309 Validation of the Newly Developed Multiple Allergen Simultaneous Test in Korea
Jungsoo Lee, Howard Chu, Hemin Lee, Jung U Shin, Chang Ook Park, Kwang Hoon Lee, Kwang Hoon Lee, Hong Kyu Kang
A310 Assessment of Symptoms Severities of Allergic Rhinitis Patients Sensitive to Multiple Allergens in Skin Prick Test
Dong Chang Lee, Geun Jeon Kim, Jae Hyung Hwang, Jin Bu Ha, Su Hee Jeong
A311 Diurnal Temperature Range and Emergency Department Visits for Asthma in Korea 6 Cities
Ho Kim, Shinha Hwang, Whahee Lee
A312 Mannan-Binding Lectin Serum Levels in Atopic Mongolian Adults
Enkhbayar Bazarsad, Logii Narantsetseg, Munkhbayarlakh Sonomjamts
A313 Prevalence of Doctor Diagnosed Atopic Eczema, during 2003-2014 in KOREA ; Using Big Data of 48.1 Million South Korean Health-Care Records
Gwang-Cheon Jang, Hyun-Hee Lee, Chang-Jong Lee, Huynsun Lim
A314 Association of Recurrent Wheeze with Lung Function and Airway Inflammation in Preschool Children
Ji-Eun Soh, Dae-Jin Song, Ji-Won Kwon, Hyung Young Kim, Ju-Hee Seo, Byoung-Ju Kim, Hyo-Bin Kim, So-Yeon Lee, Gwang-Cheon Jang, Woo Kyung Kim, Young-Ho Jung, Soo-Jong Hong, Jung Yeon Shim
A315 Mannan-Binding Lectin Serum Levels in Healthy Mongolian Adults
Enkhbayar Bazarsad, Logii Narantsetseg, Munkhbayarlakh Sonomjamts
A316 Rotanebuliser
Prabhakarrao Pv, Ranjitha Nadendla
A317 The Level of Serum Interleukin 13 and Interleukin 17A and Its Effect Factors in Children with Asthma
Juan Fang, Jing Zhao
A318 Is Vitamin D Insufficiency Also Involved in Childhood Asthma in South Korea?
Dae-Jin Song, Sungchul Seo, Young Yoo, Yu-Ri Kim, Ji Tae Choung, Jee Hoo Lee
A319 Collection of Nasal Secretions for Measurement of Local IgE: A Quest for the Best Method
Margot Berings, Natalie De Ruyck, Claus Bachert, Philippe Gevaert, Gabriële Holtappels
A320 The Role of Claudin 5 in a Murine Model of Asthma
Pureun-Haneul Lee, Byeong-Gon Kim, Choon-Sik Park, George D Leikauf, An-Soo Jang
A321 Claudin-4 in a Murine Model of Asthma: Modulation By Acrolein, a Highly Reactive Unsaturated Aldehyde
Byeong-Gon Kim, Pureun-Haneul Lee, Choon-Sik Park, An-Soo Jang
A322 Efficacy and Safety of Sublingual Immunotherapy in House Dust Mite Sensitized Children with Allergic Rhinitis
Yang Park
A323 The Association of Vitamine D Deficiency and Skeletal Muscle Dysfunction in Chronic Airway Disease
Min-Su Sohn, Hyun Jung Jin, Dong-Won Lee, Jun-Hong Ahn, Jin Hong Chung
A324 Bacteria Derived Extracellular Vesicles in Indoor Dust Is Closely Associated with Airway Disease and Lung Cancer: Analysis of Indoor Dust’s Microbiome and IgG Sensitization of Indoor Bacteria Derived Extracellular Vesicles
Sae-in Kim, Han-Ki Park, Do-Yeon Kim, Mina Rho, Jun-Pyo Choi, Yoon-Keun Kim
A325 Clinical Care Program for Childhood Asthma (CCP-Childhood Asthma); A Multidisciplinary Team Care at Samitivej International Children’s Hospital
Wasu Kamchaisatian, Thitikul Hiranras, Surinda Wongpun, Phornthip Chiraphorn, Anupan Tantachun, Wannipa Wongrassamee, Planee Vatanasurkitt, Naratip Somboonkul, Nattipat Juthacharoenwong, Surangkana Techapaitoon, Montri Tuchinda
A326 Continuous B Cell Stimulation with CD40 Ligand Induce IgE Isotype Switching
Jae Ho Lee, Sejin An
A327 Effects of Interleukin-9 on Allergen-Specific Immunotherapy in a Mouse Model of Allergic Rhinitis
Ji-Hyeon Shin, Soo Whan Kim, Si Won Kim, Jun Myung Kang, Boo-Young Kim, Byung-Guk Kim
A328 Usefulness of Exhaled Nitric Oxide for Evaluating Wheeze and Airway Hyperresponsiveness in Preschool Children
Jung-Won Lee, Ji-Won Kwon, Woo Kyung Kim, Hyung Young Kim, Hyo-Bin Kim, Ju-Hee Seo, So-Yeon Lee, Gwang-Cheon Jang, Young-Ho Jung, Soo-Jong Hong, Byoung-Ju Kim, Dae-Jin Song, Jung Yeon Shim
A329 Systemic Cyclosporine Treatment in Hand Eczema Patients
Kyung Ho Kim
A330 Lipid Profiles and Adipokines in Korean Children with Atopic Dermatitis
Young Yoo, Won Suck Yoon, Sungchul Seo, In Soon Kang, Jae Won Choi, Hye-Young Lim, Ji Tae Choung
A331 Validation of Montelukast and Levocetirizine Combination Tablet Versus Individual Tablets in the Treatment of Moderate to Severe Persistent Allergic Rhinitis Among Adult Filipinos Seen at the Philippine General Hospital-Outpatient Department
Michelle Buela
A332 Efficacy of Makyokansekito on Treatment of Wheezing Lower Respiratory Tract Infection in Children: A Retrospective Study of 68 Patients
Koji Nishimura
A333 Serum Eosinophilia and Total IgE Are Associated with the Risk of Allergic Sensitization and Allergic Symptoms in Two Years Follow-up, Respectively
Sang Chul Park, Hyo Jin Chung, Chang-Hoon Kim, Ju Wan Kang, Seong-Chul Hong, Keun-Hwa Lee, Jaechun Lee, Hye-Sook Lee, Jeong Hong Kim
A334 The Sensitization to Russian Thistle on Mongolian Patients
Narantsetseg Logii
A335 The Association Between Air Pollution, Allergic Sensitization to Inhalant Allergens and Airway Hyperresponsiveness in Ulaanbaatar, Mongolia
Munkhbayarlakh Sonomjamts, Enkhbayar Bazarsad
A336 Pre-Coseasonal Treatment with a 5-Grass Pollen Sublingual Tablet in Adults Demonstrated a Reduction on Asthma Symptoms in Réunion Island
Bashir Omarjee
A337 Peak Expiratory Flow Rate Reference Values for Children Aged 5-14 Years Old in Beijing Urban Area
Shuo LI
A338 Soybean Storage Proteins As the Main Allergen in a Patient with Food-Dependent Exercise-Induced Anaphylaxis Due to Tofu
Miyuki Hayashi, Ruby Pawankar, Shingo Yamanishi, Toru Igarashi, Yasuhiko Itoh
A339 A Study of Allergy Skin Prick Test with Weed Pollen
Oyuntsatsral Batsaikhan, B. Gantulga, B. Enkhbayar, S. Munkhbayarlakh, L.Narantsetseg
A340 The Role of Neurotrophin in a Murine Model of House Dust Mite Induced Allergic Rhinitis
Pei-Chi Chen, Jiu-Yao Wang
A341 Mimotopes of the Major Shellfish Allergen Tropomyosin Suppress Splenocyte Proliferation and Local Cytokine Expression in a Mouse Model of Shellfish Allergy
Nicki Y. H. Leung, Christine Yee Yan Wai, Patrick S.C. Leung, Ka Hou Chu
A342 A Questionnaire Survey on Understanding of Atopic Dermatitis Among Korean Patients and Caregivers
Eun Jin Doh, Dong Hun Lee, Mira Choi, Hyun-Sun Yoon, Kyu Han Kim, Ji Soo Lim
A343 Comparison of the Dosage of Bronchodilators in the Bronchodilator Response Test in Children
Ji Hyeon Baek, Man Yong Han, Seung Jin Lee, Youhoon Jeon, Kyung Suk Lee, Young-Ho Jung, Hye Mi Jee, Youn Ho Shin
A344 The Expression and Effect of Natural Killer T Lymphocytes in Chidren with Asthma
Yi Jiang, Miao Liu
A345 Oral Provocation Test in Non-Steroidal Anti-Inflammatory Drug Hypersensitive Patients Referred to Singapore General Hospital
Chaw Su Naing, Tze Chin Tan, Yong Yeow Chong
A346 Different Phenotypes of Bhr (bronchial hyperresponsiveness) By Natural Course in Children and It’s Characteristics
Young-Ho Kim, Eun Lee, Song-I Yang, Hyun-Ju Cho, Hyung Young Kim, Ji-Won Kwon, Young-Ho Jung, Byoung-Ju Kim, Ju-Hee Seo, Ho-Jang Kwon, Hyo-Bin Kim, So-Yeon Lee, Soo-Jong Hong, Soo Hyun Kim
A347 Spectrum of Allergens Causing Allergic Rhinitis and Asthma in Urban Bangalore, India − a Study of 120 Patients
Jacqueline Elizabeth Joseph, Soumya M. S, Ruby Pawankar, Harshitha Kumar
A348 High Prevalence of Wheezing Illness and Risk Factor of Atopic Asthma Progression in Korean Preschool Children
Sohyoung Yang, Sung-Il Woo
A349 Clinical and Laboratory Screening of Primary Immunodeficiency Diseases: International Effects
Nima Rezaei
A350 The Effect of Helicobacter Pylori Infection in Atopic Individuals
Sukran Kose, Basak Gol Serin, Arzu Didem Yalcin, Süheyla Serin Senger, Mehmet Erden, Ertan Serin
A351 Clinical Spectrum and Natural History of Chronic Urticaria in Hong Kong Children
Agnes Sze-Yin Leung, Ting Fan Leung
A352 Skin Prick Test Reactivity to Common Pollen Aeroallergens in Patients with Allergic Rhinitis − in Urban Bangalore, India
Harshitha Kumar, Soumya M.S., Jacqueline Elizabeth Joseph, Ruby Pawankar
A353 Seasonal Patterns of Asthma-Related ED Visits and Admissions in Children and Adolescents Who Visited Emergency Rooms of Korea in 2007-2012
Eun Hee Chung
A354 Prevalence of Atopic Dermatitis and Its Associated Risk Factors in Elementary School Children: A Cross-Sectional Study in Gyeonggi-Do, South Korea
Eunji Kim, Young Yoo, Ji Tae Choung, Sungchul Seo, In Soon Kang, Jue Seong Lee, Ji Hyen Hwang
A355 Intralymphatic Immunotherapy for Dermatophagoides Farinae, Dermatophagoides Pteronyssinus, Cat, and/or Dog Allergy in Patients with Allergic Rhinitis: 1 Year Follow-up
Sang Min Lee, Joo Hyun Jung, Seung Joon Choi, Eugene Joe, Hyunjung Hwang, Shin Myung Kang, Yu Jin Kim, Sun Young Kyung, Jeong-Woong Park, Sung Hwan Jeong, Sang Pyo Lee
A356 Respiratory Syncytial Virus Regulates IL-33 Expression in Bronchoalveolar Cells and Lung Tissue in Vivo
Alina Gaisina, Igor Shilovskiy, Aleksandra Nikonova, Oleg Kamyshnikov, Musa Khaitov, Alexander Mitin, Komogorova Viktoriya, Marina Litvina, Nina Sharova
A357 The Prevalence of Parent-Perceived Food Hypersensitivity in Pre-School Children Attending a Tertiary Care Hospital in Malaysia
Faizah Mohamed Jamli
A358 Th2 Dominant Airway Inflammation Induced By House Dust Mite Chitin Is Dependent on TNF-a and NKT Cell
Da-Il Yoon, Jun-Pyo Choi, Han-Byul Choi, Yoon-Keun Kim, Hyeon-Il Choi
A359 Geographic Variations in the Patterns of Sensitization to Aeroallergens in Korean Adults: A Multi-Center Study
Mingyu Kang, Mi Yeoung Kim, Sujeong Kim, Eun-Jung Jo, Seoung-Eun Lee, Woo-Jung Song, Sang Min Lee, Chansun Park, Yoon-Seok Chang, Jaechun Lee, Young-Koo Jee, Inseon S Choi, Kyung-up Min, Sang-Heon Cho
A360 Experimental Mouse Model of Asthma Induced By Dust Mite Dermatophagoides Pteronyssinus allergenic Extract
Anton Laskin, Oleg Kamyshnikov, Alexander Babakhin, Valentina Berzhets, Musa Khaitov
A361 Severe Refractory Pulmonary Complications in Children with Mycoplasma Pneumoniae Pneumonia
Sejin An, Jae Ho Lee
A362 Usefulness of Interactive e-Learning Education Program for Asthma Guideline
Sung-Yoon Kang, Yoon-Seok Chang, Kyung-up Min, Sang-Heon Cho, Sae-Hoon Kim, Yong Eun Kwon, Young-Koo Jee, Tae-Bum Kim, Hee-Bom Moon, Hye-Kyung Park
A363 Airway Inflammation Induced By House Dust Mite Derived Vesicles Is Mainly Induced By LPS Derived from Gram Negative Bacteria in Dust Mite.
Sang-Yoon Kim, Jun-Pyo Choi, Han-Ki Park, Ji-Hyun Lee, Yoon-Keun Kim
A364 Changes in the Recognition of Causal Allergen, Its Avoidance, and Allergen Specific Immunotherapy after Skin Prick Test / Intradermal Test, Nasal Provocation Test, and Intralymphatic Immunotherapy in Patients with Allergic Rhinitis: 1 Year Follow-up
Hyunjung Hwang, Eugene Joe, Sang Min Lee, Seung Joon Choi, Joo Hyun Jung, Yong Han Seon, Shin Myung Kang, Yu Jin Kim, Sun Young Kyung, Jeong-Woong Park, Sung Hwan Jeong, Sang Pyo Lee
A365 Laboratory Diagnostic of Staphylococcal Sensitization
Natalya Khramykhoverchenko
A366 Th-17 Regulatory Cytokines Enhance Neutrophil Production of IL-17 during Asthma
Saleh Al Muhsen, Asma Sultana, Rabih Halwani, Ahmed Bahammam
A367 Diagnostic Value of Serum Total IgE and Prediction of Cut-Off Value to Recommend Mast in Allergic Rhinitis
Hyung Chae Yang, Sun Kyung Kim, Kwang Il Nam
A368 Diagnostic Value of an Increase in FEV1 and/or FVC >12% and >200 mL from Baseline after Bronchodilators for Diagnosis of Asthma
Jeong-Eun Kim, Ju Suk Lee, Ji Hyun Lee, Kyung Woo Kang
A369 Combined Use of Fractional Exhaled Nitric Oxide and Bronchodilator Response in Predicting Future Loss of Asthma Control Among Children with Atopic Asthma
Je-Kyung Kim, Youn-Soo Hahn, Jae-Yub Jung
A370 Antigen-Specific IgA Plays an Important Role in Mucosal Immune Response in Allergic Children : Measurement of Secretory IgA and Antigen-Specific IgA
Yosuke Baba, Sususmu Yamazaki, Eisuke Inage, Mari Mori, Yoshikazu Ohtsuka, Masato Kantake, Toshiaki Shimizu, Asuka Honjoh, Tomoaki Yokokura
A371 Why Teaching Pediatrics Trainees about Anaphylaxis and Its Acute Management Is Essential: Cross Sectional Survey.
Mehdi Adeli, Shaza Ali Mohammed Elhassan, Caroline Beck
A372 Prevalence and Clinical Characteristics of Local Allergic Rhinitis in Children
Min Sun Na, Heysung Baek, Seung Jin Lee, Ji Hyeon Baek, Jungwon Yoon, Sun Hee Choi, Young-Ho Jung, Youn Ho Shin, Man Yong Han
A373 House Dust Mites Sublingual Immunotherapy Can Influence the Long-Term Evolution of Severe Atopic Dermatitis and the Progression to Respiratory Allergy.
Enrico Compalati, Maurizio Marogna
A374 The Positive Distribution Characteristics of 90 Food Specific IgG in Patients with Allergic Diseases
Huimin Huang, Baoqing Sun, Mingyu BAI, Yiting Huo, Peiyan Zheng, Nili Wei, Wenting Luo
A375 Evaluation of Serum Levels of Osteopontin As a Potential Biomarker of Immune Activation in Patients with Allergic Diseases
Elisa Villa, Anand Andiappan, Rosalba Minisini, Olaf Rötzschke, Elena Boggio, Luca Gigliotti, Nausicaa Clemente, Annalisa Chiocchetti, Umberto Dianzani, Mario Pirisi
A376 Prevalence of Allergic Rhinitis in 3-6-Year-Old (preschool) Children in Chiba City (urban area), Japan
Fumiya Yamaide, Syuji Yonekura, Naoki Shimojo, Yuzaburo Inoue, Yoshitaka Okamoto
A377 Comparative Efficacy of Combination Nebulized Salbutamol and Fluticasone Propionate and Nebulized Salbutamol in Children with Mild Moderate Asthma Attack
Retno Asih Setyoningrum, Landia Setiawati, Sri Sumei, Deddy Iskandar
A378 Characteristics of Children Hospitalized with Asthma in West Nusa Tenggara General Hospital Mataram Indonesia
Indriyani Sang Ayu Kompiyang
A379 Identification of Phenotypes in Allergic Bronchopulmonary Aspergillosis Using Cluster Analysis
Tsuyoshi Oguma, Jun Tanaka, Katsuyoshi Tomomatsu, Koichiro Asano
A380 The Roles of Type 2 Innate Lymphoid Cells (ILC2) in Chronic Rhinosinusitis (CRS)
Keisuke Uno, Yoshinori Matsuwaki, Kazuhiro Omura, Eika Hayashi, Norifumi Tatsumi, Hirohito Kita, Nobuyoshi Otori, Hiromi Kojima
A381 Respiratory Symptoms, Signs and Spirometry Indexes Comparision in 7-12 Years Old Girls in Esfahan Metropolis and Its Far Suburb
Mohammadreza Fatemi Khorasgani
A382 Induction of Kruppel-like Transcription Factor (KLF4&5) By Baker’s Yeast Mannan in Human Bronchial Epithelial and Smooth Muscle Cells
Dukhee/Betty Lew, Kim/S. Lemessurier, Joseph/a Moore, Jeoung-Eun Park, Ae-Kyung Yi, Chi/Young Song, Kafait/U Malik
A383 Korean Profile in Childhood Asthma Severity Classification
Dongin Suh, Ja Kyoung Kim, Hyeon-Jong Yang, Bong-Seong Kim, Youn Ho Shin, So-Yeon Lee, Geunhwa Park, Woo Kyung Kim, Hyo-Bin Kim, Heysung Baek, Dae Hyun Lim, Dae Hyun Lim, Jin Tack Kim
A384 Prevalence of Food Sensitization, IgE-Mediated and Non-IgE-Mediated Food Allergy Among Pediatric Patients Diagnosed with Autism Spectrum Disorders
Aimee Lou Manalo Nano
A385 Component-Resolved Diagnostic Study of Dermatophagoides Pteronyssinus Major Allergen Molecules in a Southern China
Wenting Luo, Baoqing Sun
A386 Risk Factors for Systemic and Local Reactions to Subcutaneous Allergen Immunotherapy
Hikmet Tekin Nacaroglu, Semiha Bahceci Erdem, Ozlem Sumer, Sait Karaman, Canan Sule Unsal Karkiner, Suna Asilsoy, Ilker Gunay, Demet Can
A387 Literature Review and Current Treatment Options for Cyclical Anaphylaxis
Danielle Kiers
A388 The Effect of Surfactant Protein D in Acute Lung Injury and Pulmonary Fibrosis Induced By Bleomycin
Hsu Han Yin, Jiu-Yao Wang
A389 Activation of Endothelial Cells to Release Hsp90, an Activator of the Prekallikrein-High Molecular Weight Kininogen (HK) Complex
Allen Kaplan, Kusumam Joseph, Baby G. Tholanikunnel
A390 The Effect of Climatic Treatment in 51 Asthmatic Children from Areas Severely Polluted Environment of Northern Moravia, Czech Republic
Radim Dudek
A391 Comparison of Some Vitamin Groups in Asthmatic Patients
Gulden Bilgin, Hatice Surer, Aytun Sadan Kilinc, Dogan Yucel
A392 Sensitization in Children with Atopic Dermatitis: A Single Center Study
Ji Young Lee, Jihyun Kim, Hea-Kyoung Yang, Minji Kim, Sang-Il Lee, Kangmo Ahn
A393 Staphylococcal Enterotoxin IgE Sensitization: A Risk Factor for COPD Overlap in the Elderly Asthma?
Sung Do Moon, Byung-Keun Kim, Sang-Heon Cho, Kyung-up Min, Yoon-Seok Chang, Heung Woo Park, Hye-Ryun Kang, Woo-Jung Song, Min-Koo Kang, Ju-Young Kim, Kyonghee Sohn, Ha Kyung Won, Seoung-Eun Lee, Kyung-Mook Kim, Claus Bachert
A394 The Effects of Probiotics and PparÎ3 on the Murine Model of Allergic Asthma
Miao-Hsi Hsieh, Jiu-Yao Wang
A395 Adult Patients’ Views on the Design of Adrenaline Autoinjectors
Helen Smith, Clare Brown, Christina Jones, Mark Davies
A396 CCL22 miRNA modulated Th1 responses and induced therapeutic effects on OVA-induced mouse model of asthma
Won Suck Yoon
A397 Clinical, Histological, and Skin Microbiome Characteristics of Head and Neck Dermatitis in Atopic Dermatitis
Hemin Lee, Howard Chu, Jungsoo Lee, Jung U Shin, Chang Ook Park, Kwang Hoon Lee, Seo Hyeong Kim, Ji Yeon Noh, Ji Hye Kim
A398 MicroRNA-432 modulates Th1 responses and induced therapeutic effects in atopic like murine model.
Won Suck Yoon
A399 Case Report of Near-Fatal Asthma Due to Snail Allergy in a House Dust Mite-Allergic Adult
Jean-Pierre L’huillier, Jean-Eric Autegarden, Catherine Bertrand, Dominique Tardy
A400 Relationship Between Gut Microbiota in the First 3 Months of Life and Infant Immune Function at Age 12 Months
Intan Hakimah Ismail, Mimi Tang, Paul Licciardi, Frances Oppedisano, Robert Boyle, Roy Robins-Browne
A401 A Pediatric Case of Food-Dependent Exercise-Induced Anaphylaxis Due to Spice Allergy
Hisako Yagi, Harumi Koyama, Yutaka Nishida, Takumi Takizawa, Hirokazu Arakawa
A402 Correlations Between Objective Severity Score and Each of the Subjective Severity Intensity in Atopic Dermatitis
Hong Kyu Kang, Hemin Lee, Jungsoo Lee, Jung U Shin, Kwang Hoon Lee, Kwang Hoon Lee, Howard Chu, Chang Ook Park
A403 Barrier Related Gene Mutations in Atopic Dermatitis
Na Young Yoon, Hyeyoung Lee, Seong Jun Seo, Eunhee Choi, Hye-Young Wang, Minyoung Jung, Eung Ho Choi, Dong Hye Kim
A404 Clinical Utility of Basophil Activation Test (BAT) in the Diagnosis of Drug Induced Anaphylaxis
Joo-Hee KimYoung-Sook Jang, Jeong-Hee Choi, Sunghoon Park, Young Il Hwang, Seung Hun Jang, Ki-Suck Jung
A405 Feeding Shapes the Colonization of Gut Microbiota and Associated with Total IgE in Infant
Mi-Jin KangDongin Suh, Eun Lee, Kil Yong Choi, Young-Ho Jung, Song-I Yang, Bong-Soo Kim, Ha-Jung Kim, Juneyoung Koh, Hyun-Jin Kim, Kangmo Ahn, Youn Ho Shin, Hyun-Ju Cho, Byoung-Ju Kim, Young-Ho Kim, Yean Jung
A406 CD8+T Cell-Intrinsic Smad4 Suppresses Th2 Responses in the Pathogenesis of Contact Hypersensitivity
Mizuko Mamura, Jeong-Hwan Yoon, Susumu Nakae, Inkyu Lee, Isao Matsumoto, Takayuki Sumida, Jin Soo Han, Katsuko Sudo, Ji Hyeon Ju
A407 Immune-Modulatory Genomic Properties Differentiate Gut Microbiotas of Infants with and without Eczema
Gaik Chin Yap, Wen Tso Liu, Seungdae Oh, Pei Ying Hong, Chiung Hui Huang, Marion Aw, Lynette Shek, Bee Wah Lee
A408 The Effect of Medication in OSA Patients with Allergic Rhinitis
Young Seok Byun, Sung Wan Kim, Tae Kyung Koh, Joong-Saeng Jo, Kun Hee Lee, Chul Kwon, Sung-Hwa Dong
A409 A Case of Generalized Pustular Psoriasis Mimicking Acute Generalized Exanthematous Pustulosis
Myung Shin Kim, Chansun Park
A410 Anaphylaxis Caused By Gummy Jelly Ingestion: A Case Report
Han Seok Cho, Min-Ju Kim, Min Ji Kim, Young Ok Park, Hye Yeong Lee, Hee Seong Kim, Eun Lee, Hyun-Ju Cho, Jinho Yu, Soo-Jong Hong, Keum Hee Hwang
A411 Serum Folliculin As a Novel Biomarker for Asthma
Jung-Hyun Kim, You Sook Cho, Sae-Hoon Kim, Hyouk-Soo Kwon, Mira Yoo, Hyo-Jung Kim, So-Young Park, Bomi Shin, So Young Park, Bomi Seo, Min-Gu Kim, Hee-Bom Moon, Jin-Ah Park, Tae-Bum Kim, Jaemoon Lee
A412 Corticosteroid Nasal Irrigations after Endoscopic Sinus Surgery in the Management of Chronic Rhinosinusitis with Asthma
Jin Hyeok Jeong, Tae Wook Kang, Han Seok Yoo, Yong Hee Cho, Seok Hyun Cho, Kyung Rae Kim
A413 Capsaicin Injection in Neonatal Period Potentiates Intensity and Duration of Atopic Dermatitis of Rats.
Jue Seong Lee, Sun-Ho Kee, Sewon Kim, Young Yoo, Heung Sik Na, Seung Keun Back
A414 Comparison Between the Impulse Oscillometry System, Spirometry, Feno, Lung Clearance Index and Asthma Control and Exacerbation Status.
Seung Jin Lee, Bo Seon Seo, Ji Hyeon Baek, Kyung Suk Lee, Young-Ho Jung, Hye Mi Jee, Youn Ho Shin, Man Yong Han, Mi-Ae Kim
A415 The Association of Exhaled Nitric Oxide and Airway Hyperresponsiveness in Patients with and without Asthma
Young-Hee Nam, Dong Sub Jeon, Soo-Keol Lee
A416 Effects of Air Pollution on Allergic Rhinitis in Korea
Jisun Park
A417 Exhaled Nitric Oxide in Korean Children with Allergic Rhinitis
Seung Hyun Moon
A418 A Questionnaire of Children with Asthma or Asthma and Allergic Rhinitis
Rong Jun Lin, Ren Zheng Guan
A419 A Case of Trimebutine-Induced Morbilliform Skin Eruption
Gyeong Yul Park, Hyun-Sun Yoon
A420 Comparison of Methacholine and Mannitol to Predict Exercise-Induced Bronchoconstriction in Children with Asthma
Woo-Hyeok Choi, Heysung Baek
A421 Different Inflammatory Mechanisms of Human Metapneumovirus and Respiratory Syncytial Virus
Jin-Sung Park, Eunmi Kwon, Zac Callaway, Chang-Keun Kim, Takao Fujisawa
A422 Sputum Microbiota in Chinese Adults with Eosinophilic Versus Non-Eosinophilic Asthma
Qingling Zhang, Rihuang Qiu, Naijian Li, Zhaowei Yang, Jing Li, Kian Fan Chung, Nanshan Zhong
A423 Which Clinical Features Are Useful in Predicting Presence of Staphylococcus Aureus colonization/Infection in Childhood Atopic Dermatitis?
Kam Lun E. Hon, Yin Ching K. Tsang, Ting Fan Leung
A424 Clinical Significance of Increased VEGF, TGF-Î21, and YKL-40, a Chitinase like Protein, in Serum of the Children with Asthma
Yoon Young Jang, Hai Lee Chung, Seung Gook Lee, Ji Hyun Na, Jong Hoon Lee
A425 Analysis of Follow-up Results of Mannitol Challenge Test in Asthma Patients
Young-Hee Nam, Dong Sub Jeon, Soo-Keol Lee
A426 Analysis of 68 Oral Walnut Challenge Tests
Mikita Yamamoto, Sakura Sato, Noriyuki Yanagida, Ayako Ogawa, Kanako Ogura, Kyohei Takahashi, Kenichi Nagakura, Shigehito Emura, Tomoyuki Asaumi, Katsuhito Iikura, Motohiro Ebisawa, Yu Okada
A427 Effectiveness of Air Filters Intervention in Allergic Rhinitis
Jiaying Luo, Xiao Lan, Baoqing Sun, Zhao Chen, Guiyuan Sun, Shimin Li, Jiaqing Hu
A428 The Relationship Between Airway Hyperresponsiveness to Mannitol and Atopy in Asthmatic Children
Woo-Hyeok Choi, Heysung Baek
A429 Anaphylactoid Reactions to N-Acetylcysteine in the Treatment of Aacetaminophen Overdose
Young-Hee Nam, Dong Sub Jeon, Hee-Joo Nam, Yeo Myeong Noh, Sang Hee Kim Kim, Ye Suel Park, Soo-Keol Lee
A430 Effect of Prenatal Maternal Distress and GSDMB Polymorphism on the Development of Recurrent Wheezing in Early Childhood: COCOA Study
Yean Jung Choi, Si Hyeon Lee, Young-Ho Kim, Mi-Jin Kang, Hyun-Ju Cho, Eun Lee, Song-I Yang, Youn Ho Shin, Kangmo Ahn, Kyung Won Kim, Yoon Hee Kim, So-Yeon Lee, Hyoung Yoon Chang, In Ae Choi, Kyung-Sook Lee, Yee-Jin Shin
A431 Vitamin D Level in Allergic Rhinitis: A Systemic Review and Meta-Analysis
Yoon Hee Kim, Min Jung Kim, In Suk Sol, Seo Hee Yoon, Young a Park, Kyung Won Kim, Myung Hyun Sohn, Kyu-Earn Kim, Yong Ju Lee
A432 Implication of Inspiratory and Expiratory Resistance and Reactance in Children with Asthma
In Suk Sol, Kyu-Earn Kim, Yoon Hee Kim, Min Jung Kim, Seo Hee Yoon, Yong Ju Lee, Kyung Won Kim, Young a Park, Myung Hyun Sohn
A433 The Association of Asthma Predictive Index with Asthma in Preschool Children with Recurrent Wheeze
Sung Joo Park, Ji-Won Kwon, Woo Kyung Kim, Hyung Young Kim, Hyo-Bin Kim, Ju-Hee Seo, So-Yeon Lee, Gwang-Cheon Jang, Young-Ho Jung, Soo-Jong Hong, Byoung-Ju Kim, Dae-Jin Song, Yun Seok Yang, Jung Yeon Shim
A434 Clinical Significance of Serum Total IgE Levels in Children with RSV-Associated Lower Respiratory Illness
Yoon Young Jang, Hai Lee Chung, Ji Hye Kim, Hyun Seok Lee, Chang Ho Lee
A435 Development of a Oak Pollen Emission and Transport Modeling Framework in South Korea
Changbum Cho, Yun-Kyu Lim, Kyu Rang Kim, Mijin Kim, Baek-Jo Kim
A436 Temperature, Humidity, and Air Pollution Affect Atopic Dermatitis Symptoms in Infants and Young Children
Young-Min Kim, Youngshin Han, Jihyun Kim, Hae-Kwan Cheong, Byoung-Hak Jeon, Kangmo Ahn
A437 Effects of Compound V on Pulmonary Fibrosis Model
Chuang/Yao Ming, Jiu-Yao Wang, Ye/Yi Ling
A438 Vitamin D Level and the Correlation with IgE in Children with Allergic Respiratory Diseases in Guangzhou China
Huimin Huang, Baoqing Sun, Yun Chen, Peiyan Zheng, Nili Wei, Wenting Luo
A439 Two Case Reports of Eosinophilic Gastroenteritis Associated with Allergic Disease
Do Hyeong Lee, Gil-Soon Choi, Hee-Kyoo Kim, Han Su Park
A440 Genome-Wide Association Study (GWAS) May Identify Common Genetic Variations Both in Immediate and Delayed Drug
So-Young Park, Hyo-Jung Kim, Bomi Seo, Jung-Hyun Kim, Min-Gu Kim, Hyouk-Soo Kwon, You Sook Cho, Hee-Bom Moon, Tae-Bum Kim, Yoon Su Lee
A441 Development of a Questionnaire for Secular Change of Atopic Dermatitis from Birth to 19-Year-Old.
Akio Tanaka, Satoshi Morioke, Yukihiro Ohya, Naoki Shimojo, Akira Akasawa, Michihiro Hide, Hiroko Shizukawa
A442 Evaluation of the Adherence Starts with Knowledge-20 (ASK-20) to Inhaled Drug in Patients with Bronchial Asthma
Naoto Watanabe
A443 The Epidemiology and Clinical Manifestation of Hmpv Infection in Children during Recent 4 Years: 2011-2014
Meeyong Shin, Myeong Sun Jang
A444 Neutropenia Induced By Intravenous Immunoglobulin
Young-Hee Nam, Yeo Myeong Noh, Dong Sub Jeon, Hee-Joo Nam, Sang Hee Kim Kim, Ye Suel Park, Soo-Keol Lee
A445 A First Case of Lymphocytic Interstitial Pneumonitis in Healthy Child
Ji-in Jung, Ha-Su Kim, Hyun-a Kim, Jin-a Jung
A446 Cytokine Production upon House Dust Mite Stimulation of Cord Blood Mononuclear Cells from Caesarean Section-Delivered Singaporean Infants
Anne Goh, Rajeshwar Rao, Bindu Nandanan, Ruurd Van Elburg, Chua Mei Chien, Juandy Jo, Johan Garssen, Johan Garssen, Leon Knippels, Elena Sandalova, Wen Chin Chiang
A447 Dress Syndrome with Acute Interstitial Nephritis Caused By Quinolone and Nonsteroidal Anti-Inflammatory Drugs
Young-Hee Nam, Ji Young Juong, Soo Jin Kim, Eun Young Kim, Su Mi Lee, Young Ki Son, Hee-Joo Nam, Ki-Ho Kim, Soo-Keol Lee
A448 IL-23 Roles in the Development of House Dust Mite Allergic Sensitization and Asthma
Da-Eun Park, Hye-Ryun Kang, Heung Woo Park, Hyun Seung Lee, Yoon-Seok Chang, Jung-Won Park, Sang-Heon Cho, Kyung-up Min, Woo-Jung Song
A449 Exposure Profile of Indoor Risk Factors in Dwellings of Children with Atopic Dermatitis
Hyunwook Lim, Sungchul Seo, Ji Tae Choung, Young Yoo, Jun-Sik Park, Byung Kwan Kim
A450 Epidemiological Characterization of Blood Eosinophils in the Elderly Population
Ha Kyeong Won, Hye-Ryun Kang, Byung-Keun Kim, Sung Do Moon, Ju-Young Kim, So-Hee Lee, Woo-Jung Song, Heung Woo Park, Min-Koo Kang, Sun-Sin Kim, Sang-Heon Cho, Kyung-up Min, Yoon-Seok Chang, Kyoung Hee Sohn, Kyung-Mook Kim, Ki-Woong Kim, Hak Chul Jang
A451 Stevens-Johnson Syndrome Caused By Methotrexate in the Treatment of Psoriasis
Young-Hee Nam, Dong Sub Jeon, Hee-Joo Nam, Yeo Myeong Noh, Sang Hee Kim Kim, Ye Suel Park, Soo-Keol Lee
A452 Genetic Determinants for Lung Function Growth in Asthmatic Children
Ting Fan Leung, Man Fung Tang, Hing Yee Sy, Wa Cheong Chan, Wilson Wai San Tam
A453 The Power of Allergen Specific Ig E in the Classification of Rhinitis, Korean National Hanes 2010
Seung Kyu Chung, Sujin Kim, Sang Duk Hong, Hyo Yeol Kim Hyo Yeol Kim, Hun-Jong Dhong, Jong in Jeong
A454 Analysis of Allergen Immunotherapy Practice and Patients’ Knowledge and Attitude about Allergen Immunotherapy in a Single Tertiary Hospital in Korea
Young-Hee Nam, Dong Sub Jeon, Soo-Keol Lee
A455 Roles of Staphylococcal Enterotoxin B in House Dust Mite-Induced Acute Asthma Models
Ji Won Lee, Mingyu Kang, Soon-Hee Kim
A456 A Clinical Comparison of Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome in a Single Tertiary Hospital in Korea
Young-Hee Nam, Dong Sub Jeon, Hee-Joo Nam, Yeo Myeong Noh, Sang Hee Kim Kim, Ye Suel Park, Soo-Keol Lee
A457 The Beneficial Effect of Lactobacillus Gasseri PM-A0005 and Its Immunoregulatory Protein PMA5P40 on Milk-Induced Allergic Enteritis
Yung-I Hou, Jiu-Yao Wang
A458 Relationship Between Serum Folate Levels and Risks of Allergic and Respiratory Diseases in Early Childhood: The Mothers and Children’s Environmental Health Study
Ja Hyeong Kim, Seol Jae Hee, Eun-Hee Ha, Hyesook Park, Mina Ha, Yun-Chul Hong, Yangho Kim, Namsoo Chang
A459 Effects of Vitamin D in Patients with Chronic Rhinosinusitis
Yuta Soma, So Watanabe, Ruby Pawankar, Ruby Pawankar, Harumi Suzaki, Harumi Suzaki, Hitome Kobayashi
A460 Clinical Features of Systemic Contact Dermatitis from Ingestion of Rhus
Young-Hee Nam, Chansun Park, Soo-Keol Lee
A461 Sublingual Immunotherapy Efficacy in Patients with Atopic Dermatitis in Korea
Jongrok Lee, Jooyoung Roh, Haryeong Ryu
A462 Characteristics of Serious Adverse Drug Reactions in a Tertiary University Hospital
Cheol-Woo Kim, Jae Hwa Cho, Mi Ra Eom, Ji Young Kang, Hye Gyeung Lee
A463 Eyelid Dermatitis: Patch Test Results during a 15-Year Period in Korea and Evaluation of Metal Contents in Eye Shadows
Hae Young Choi, Hye Jin Lee, Ju Yun Woo, Ji Yeon Byun, You Won Choi
A464 Relationship Between Lipid Levels and Risks of Allergic and Respiratory Diseases in Early Childhood: The Mothers and Children’s Environmental Health Study
Ja Hyeong Kim, Eun-Hee Ha, Hyesook Park, Mina Ha, Yun-Chul Hong, Yangho Kim, Namsoo Chang
A465 IL-32 in the Induced Sputum of Patients with Asthma
Jae-Woo Kwon, Hun Soo Chang, Jeong-Seok Heo, Jong-Uk Lee, Jong-Sook Park, Eusom Kim, Soo Hyun Kim, Choon-Sik Park
A466 Clinical Characteristics of Patients with Chromium Allergy in a Single University Hospital in Korea
Hae Young Choi, Ji Yeon Byun, Ju Yun Woo, You Won Choi
A467 Efficacy and Safety of Oral Acitretin in Chronic Hand Eczema
Hyun-Ju Jin, Jin-Hwa Son, Jeong-Min Kim, Gun-Wook Kim, Je-Ho Mun, Margaret Song, Hyun-Chang Ko, Moon-Bum Kim, Hoon-Soo Kim, Byung Soo Kim
A468 Atypical Antipsychotics and Anticholinergic Agents Mimicking Anaphylaxis
Sheryl Van Nunen, Dinh Van Nguyen, Anthony Elias, Susannah Olivia Lauer
A469 Introducing Reach (Reliable Estimation of Atopic dermatitis in ChildHood): Novel, Questionnaire-Based Diagnostic Criteria for Childhood Atopic Dermatitis
Seung-Chul Lee, Ho-June Lee, Jung Min Bae
A470 Comprehensive Assessment to Identify the Causative Factors in Oral Allergy Syndrome
Emi Ono
A471 Comparison of Interpretation Methods in Allergic Skin Test
Sung-Hwa Dong, Tae Kyung Koh, Young Seok Byun, Sung Wan Kim, Joong-Saeng Jo, Chul Kwon, Kun Hee Lee
A472 Refraining Aminophylline Use Increases Hospitalization Among Children with Acute Asthma: A 10-Years Retrospective Cohort Study
Li-Fan Liu
A473 The Prevalence and Risk Factors of Atopic Dermatitis from Nationwide Study for Korean School Students
Sunghee Lee
A474 Probiotic Recombination Protein Effect on Atopic Dermatitis
Wei-Leng Chen, Jiu-Yao Wang
A475 Allergic Sensitization Status in Various Inflammatory Skin Diseases
Youin Bae, Gyeong-Hun Park
A476 Two Cases of Good’s Syndrome: A Rare Acquired Immunodeficiency Associated with Thymoma
Suk Yeon Kim
A477 IL-23 Has a Role to Play in the Development of Asthma in Short-Term Cigarette Smoke Exposure-Induced House-Dust Mite Allergic Model
Hyun Seung Lee, Woo-Jung Song, Mingyu Kang, Han-Ki Park, Da-Eun Park, Hye-Ryun Kang, Heung Woo Park, Yoon-Seok Chang, Hye-Young Kim, Kyung-up Min, Sang-Heon Cho, Ji-Won Lee, Boram Bae, Jung-Won Park
A478 The Relationship Between the Relevance of Allergic Disease and the Value of Non-Specific IgE
Yasuhiro Suzuki
A479 Two Caces of Prawn Allergy in Adult Patients
Ismet Bulut, Zeynep Ferhan Ozseker
A480 Early Gut Bifidobacterium Breve and B. Catenulatum Colonisation Differentially Modulate Eczema Risk in Children at High-Risk of Developing Allergic Disease
Intan Hakimah Ismail, Robert Boyle, Paul Licciardi, Frances Oppedisano, Roy Robins-Browne, Mimi Tang
A481 Effects of Chronic Repeated Exposure of Staphylococcal Enterotoxin B on Allergic Asthma Model in Mice
Ji Won Lee, Hyun Seung Lee, Mingyu Kang, Da-Eun Park, Han-Ki Park, Soon-Hee Kim, Woo-Jung Song, Hye-Ryun Kang, Heung Woo Park, Yoon-Seok Chang, Chang-Han Park, Suk-Il Chang, Sook-Hee Song, Kyung-up Min, Sang-Heon Cho, Boram Bae
A482 Skin Prick Test Result and Allergen Immunotherapy in Children with Allergic Rhinitis
Grace Shieh
A483 Role of Brp-39 in RSV-Induced Airway Inflammation in Mice
Min Jung Kim, Jung Yeon Hong, Seo Hee Yoon, Doo Hee Shim, In Suk Sol, Yoon Hee Kim, Mi Na Kim, Kyung Eun Lee, Kyung Won Kim, Myung Hyun Sohn, Kyu-Earn Kim, Jae Myun Lee
A484 Long-Term Outcomes of Twenty-Four Adults with Primary Immunodeficiency from a Single Centre in Singapore
Hiok Hee Chng
A485 Breast Feeding Increases the Risk of Food Sensitization but Does Not Affect Food Allergy in Young Children with Atopic Dermatitis
Dong Chan Kim, Song-I Yang, Hae Ran Lee, An Deok Seo, So Yeon Lee
A486 IgE Immunoadsorption Knocks Down Anaphylaxis.
Alessandro Fiocchi, Maria Cristina Artesani, Paola Francalanci, Lamia Dahdah, Thomas Schreiner
A487 Burden and Correlates of Cigarette Smoking and Respiratory Airway Obstruction: An Observation in Urban Adult Population of West Bengal (India)
Kaushik Chakraborty
A488 Blood Eosinophils Could Predict Sputum Eosinophilia? : A Comparison Between Asthma and Non-Asthmatic Chronic Cough in the Elderly
Ha Kyeong Won, Ju-Young Kim, Eun-Jung Jo, Kyoung Hee Sohn, Kyung-Mook Kim, Heung Woo Park, Yoon-Seok Chang, Sang-Heon Cho, Woo-Jung Song, Byung-Keun Kim
A489 Complementary and Alternative Medicine for Allergic Rhinitis in Japan
Syuji Yonekura, Yoshitaka Okamoto
A490 Impact of Cognitive Impairment on Asthma Control Status in Elderly Asthmatics
Gyu Young Hur, Young Min Ye, Joo-Hee Kim, Ki-Suck Jung, Junga Kim, Jae Jeong Shim, Hae-Sim Park
A491 The Association Between Respiratory Tract Infection and Reactive Oxygen Stress
Kazuhiro Sekimoto, Kazuko Sugai, Keiji Tsuchimoto, Hiromi Uehara, Masanori Ikeda
A492 The Risk Factors and Lung Function of Current Allergic Rhinitis Due to Dust Mite Sensitization
Euncho Chung, Kang Seo Park, Yean Jung Choi, Jeewon Park, Soo-Jong Hong, So Yeon Lee
A493 Cloning and Expression of Recombinant Blomia Tropicalis Dust Mite Allergen Blo t 7
Alain Jacquet, Arun Buaklin, Nat Malainual
A494 Seasonal Variations of Airborne Pollen in Bangalore, India
Roopashree S
A495 Pollen Observation and Use of Data
Kyu Rang Kim, Mijin Kim, Changbum Cho, Baek-Jo Kim, Jae-Won Oh, Mae Ja Han
A496 The Effect of Cord Serum 25-Hydroxyvitamin D (25(OH)D) on the Development of Atopic Dermatitis in First 3 Years of Life : Cocoa Study
Hyun-Ju Cho, Youn Ho Shin, Eun Lee, Young-Ho Kim, Darae Lee, Mi-Jin Kang, Song-I Yang, Kangmo Ahn, Kyung Won Kim, Yoon Hee Kim, Hye-Sung Won, Soo Hyun Kim, Suk-Joo Choi, Young Han Kim, Jong Kwan Jun, Eun-Jin Kim, Jeom Gyu Lee, So-Yeon Lee, Soo-Jong Hong, Dongin Suh
A497 Contribution of Stem Cell Factor Autocrine/Paracrine Mechanism to Aberrant Proliferation of Mast Cells
Yosuke Amagai, Akane Tanaka, Hiroshi Matsuda
A498 A Randomized Dbpc Dose-Finding Multicenter Trial of Sublingual Immunotherapy (SLIT) Allergoid Tablets in House Dust Mites (HDM) Allergic Patients
Ralph Mösges, Pauline Dieterich, Anatoli Astvatsatourov, Christoph Hüser, Jaswinder Singh, Kija Shah-Hosseini, Silke Allekotte, Enrico Compalati
A499 Depression and Allergy in the Elderly: A Community Population Analysis
Kyoung Hee Sohn, Woo-Jung Song, Byung-Keun Kim, Ju-Young Kim, Min Suk Yang, So-Hee Lee, Sae-Hoon Kim, Hye-Ryun Kang, Heung Woo Park, Sun-Sin Kim, Kyung-up Min, Sang-Heon Cho, Yoon-Seok Chang
A500 The Integrated Analysis of Correlation Between Total IgE and Other Immunological Factors in Allergic Diseases
Woo-Sung Chang, Ji-Hye Do, Yeon-Seop Kim, Dankyu Yoon, Hye-Sun Lim, Jeom-Kyu Lee, Eun-Jin Kim
A501 Pattern of Allergic Diseases Among Military Servicemen Referred to a Clinical Immunology/Allergy Service in Singapore
Bernard Thong, Yew Kuang Cheng, Jinfeng Hou, Khai Pang Leong, Justina Tan, Faith Chia, Grace Chan, Sze-Chin Tan, Teck Choon Tan, Chwee Ying Tang, Hiok Hee Chng
A502 A Case of Rifampicin-Induced Hypersensitivity Diagnosed By the Lymphocyte Activation Test with Successful Desensitization
Chan-Sun Park, Mi Yeoung Kim, Eun-Young Kim, Jae-Gook Shin, Jae-Hyeog Choi, Saegwang Park, Yeonye Kim
A503 Analysis of Individual Case Safety Reports of Drug-Induced Anaphylaxis Based on Korea Adverse Event Reporting System Database
Kyung-Hwan Lim, Jae Woo Jung, Mingyu Kang, Ju-Young Kim, Ju-Young Kim, Hyun Jeong Kim, Yeon-Ju Woo, Soo-Youn Jung, Hye-Ryun Kang, Hye-Ryun Kang
A504 Impact of Processes Certification on the Liability of Anti-Dust Mites Bed Covers
Thierry Porée, Nabile Boukhettala, Emeline Furon
A505 Localisation Kinetics of Aluminium after Subcutaneous Injection in a Rat Model
Alan David Bullimore, Matthew Heath, Simon Hewings, Murray Skinner
A506 Periostin Levels in Exhaled Breath Condensate of Competitive Athletes, Asthmatics and Healthy Subjects - Associations with Outdoor Ambient Conditions
Marcin Kurowski, Hubert Krysztofiak, Aleksandra Wardzynska, Marzanna Jarzebska, Janusz Jurczyk, Marek L. Kowalski
A507 The Role of PKR Pathway in Acute Exacerbation of Severe Bronchial Asthma
So Ri Kim, Yong Chul Lee, Dong Im Kim, Yang Keun Rhee, Heung Bum Lee, Seoung Ju Park, Yeong Hun Choe Choe, Seung Yong Park
A508 Diversity of Clinical Manifestations and Treatment Responses for Idiopathic Hypereosinophilic Syndrome
Joo-Hee Kim, Sunghoon Park, Young Il Hwang, Seung Hun Jang, Ki-Suck Jung
A509 Effect of Dexamethasone in Th17 Cell Mediating Neutrophilic Asthma
Nong Guang-Min, Jiang Min
A510 Allergen Profile for Asthma/Rhinitis and Eczema Among Patients in North India: An Immunocap Allergen Specific IgE Antibodies Assay Based Study
Nalin Nag
A511 Clinical Profile of Allergic Rhinitis in Children in Jakarta
Wahyuni Indawati
A512 Preclinical Study on the Use of Micro Crystalline Tyrosine (MCT) Adjuvants in Allergy Immunotherapy
Alan David Bullimore, Matthew Heath, Murray Skinner
A513 Genetic Diversity of Filaggrin Mutation and Its Clinical Implication in East Asian Atopic Dermatitis Patients
Seong Jun Seo, Won Jong Oh
A514 Protein and MPL Adsorption Capacities for MCT in Candidate Therapeutic Formulations for Use in Immunotherapy, Compared Against Existing Adjuvants
Alan David Bullimore, Murray Skinner, Matthew Heath, Andrew Bell
A515 Interleukin-22 Gene Variation in Inflammatory Bowel Disease
Alireza Zarebidoki, Hournaz Hasanzadeh, Salman Sadeghzade, Nima Rezaei
A516 Immunomodulatory Effects of Adipose-Derived Stem Cell Secretome in a Mouse Model of Asthma
Kyu-Sup Cho
A517 Diffuse Alveolar Hemorrhage with Positive Anti-Neutrophil Cytoplasmic Antibody in a Child : A Case Report
Sung-Woo Kim, Moo-Young Oh
A518 Clinical Analys the Serum TARC Levels As the Condition Index of Atopic Dermatitis in the Early Infancy
Munemitsu Koizumi, Kazuyo Kuzume
A519 An Analysis of the Filaggrin Gene Polymorphism in Korean Atopic Dermatitis Patients
Kui Young Park, Won Jong Oh
A520 A New Protocol for Wheat Oral Immunotherapy in Patients with Anaphylaxis
Delara Babaie, Mohammad Nabavi, Fariborz Zandieh, Mehrdad Amir Moini, Zahra Chavoshzadeh, Hamideh Seifi, Mitra Sahragard, Mehrnaz Mesdaghi, Mohammad Hassan Bemanian
A521 Clinical Characteristics of Filaggrin-Related Atopic Dermatitis Patients in Korea
Sun Young Choi, Yeon a No
A522 Early Allergy Diagnosis in Children - Self- Administered Questionnaire Vs Medical Verification
Andrzej M. Fal, Dorota Kiedik, Agnieszka Muszynska, Iwona Pirogowicz
A523 Asthma Impact on Children with Food Induced Anaphylaxis
Chikako Motomura, Masatoshi Wakatsuki, Yuko Akamine, Mihoko Iwata, Hiroshi Matsuzaki, Naohiko Taba, Yoko Murakami, Hiroshi Odajima
A524 Case Reports of Stevens-Johnson Syndrome and Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis in Systemic Lupus Erythematosus
Reni Ghrahani
A525 The Effectiveness of Oral Tolerance Induction for Wheat Allergy Using Two Different Intake Levels
Yuri Takaoka
A526 Association of Plasma Interleukin-25 Levels with Development of Aspirin Induced Airway Spasm in Asthma
Jong-Uk Lee, Jeong-Seok Heo, Da-Jeong Bae, Hyun Ji Song, Choon-Sik Park, Jong-Sook Park
A527 Transition of Allergic and Nonallergic Rhinitis after 2 Years in Korean Children: Preliminary Study
Jae Hoon Cho, Ji Ho Choi
A528 Early Onset of Psoriasis Juvenile Idiopathic Arthritis
Budi Setiabudiawan, Fiska Febriana, Reni Ghrahani, Gartika Sapartini
A529 Clinical Features of Immediate Hypersensitivity to Histamine H2 Antagonists and Their Cross Reactivity
Chan-Sun Park, Young-Hee Nam, Mi Yeoung Kim, Gil-Soon Choi
A530 Detection of Galacto-Oligosaccharide Specific IgE in Vitro
Chiung-Hui Huang, Chiung-Hui Huang, Jian Yi Soh, Lynette Shek, Lynette Shek, Dianne J. Delsing, Bee Wah Lee, Bee Wah Lee, Si Hui Goh, Wen Chin Chiang, Wenyin Loh
A531 The Association Between Serum Vitamin D Levels and Allergic Diseases in Elementary Schoolchildren
Hea-Kyoung Yang, Ji Young Lee, Minji Kim, Kangmo Ahn, Jihyun Kim, Young-Min Kim, Hye-Young Kim, Yong Mean Park, Woo Kyung KIM, So-Yeon Lee
A532 Serum Levels Specific IgE to Toxic Shock Syndrome Toxin Type 1 in Eosinophilic Chronic Rhinosinusitis with Nasal Polyp in Korean
Jongin Jeong, Sang Duk Hong, Seung Kyu Chung, Hun-Jong Dhong, Hyo Yeol Kim Hyo Yeol Kim, Sujin KIM
A533 Impacts of Rhizosphere Cleaning Effects of Potted Indoor Plants on the Symptoms and Stress of Students with Allergic Rhinitis in Newly Built Schools
Yong-Won Lee, Hana Bak, Hye-Rim Son, Si-Eun Lee, Kwang-Jin Kim, Young-Wook Lim, Ho-Hyun Kim
A534 A Case of Multiple Food Allergies with Recurrent Anaphylaxis Successively Controlled By Omalizumab
Mi-Ae Kim, Man Yong Han, Young-Ho Jung, Hye Mi Jee, Seung Jin Lee, Kyung Suk Lee
A535 Bepotastine-Induced Urticaria, Cross-Reactive with Other Antihistamines
Jasmina Golez, Jaechun Lee, Eunkyoung Lee
A536 Role of SLC26a4 in Ozone - Induced Airway Reactivity and Inflammation
Da-Jeong Bae, Chang-Gi Min, Jong-Uk Lee, Jong-Sook Park, Hun Soo Chang, Choon-Sik Park, An-Soo Jang
A537 PAR2-Antagonist Suppresses Protease-Induced Allergic Inflammation Mediated By Degradation of Lung Epithelial Tight Junction and Generation of ROS
Young-Joon Kim, Bok Kyoung Jung, Seung-Hwa Lee, Mi-Jin Kang, Sekyoo Jeong, Eun Lee, Hyun-Ju Cho, Young-Ho Kim, Song-I Yang, Seo Hee Kim, Soo-Jong Hong
A538 Novel Anti-IL-4Ra Nanocarrier Approach for the Efficient Control of Lung Tissue Inflammation during Asthma
Rabih Halwani, Saleh Al Muhsen, Asma Sultana, Achraf Al-Faraj, Rosan Kanana, Sibtain Afzal, Roaa Al Kufaidi
A539 Clinical Factors for Improved Allergen Reactivities Induced By Subcutaneous Allergen Specific Immunotherapy with House Dust Mites during 1 Year Period
Hee-Kyoo Kim, Chul-Ho Oak, Gil-Soon Choi, Ye-Jin Moon, Eun-Kee Park
A540 Cytokine Gene Polymorphisms in Iranian Patients with Kidney Acute Rejection
Alireza Zarebidoki, Mina Abrari, Ali Akbar Amirzargar
A541 Phthalate Exposure and Obesity in Atopic Dermatitis of Korean Children and Adolescents
Ju-Hee Seo, Mina Ha, Soo-Jong Hong
A542 Which Drives Chronicity of Cough in Adults: Based on the Knhanes 2010-2012
Mingyu Kang, Byung-Ha Cho, Han-Ki Park, Han-Ki Park, Kyung-Mook Kim, Chang-Han Park, Heung Woo Park, Heung Woo Park, Yoon-Seok Chang, Yoon-Seok Chang, Yoon-Seok Chang, Sook-Hee Song, Mi-Kyeong Kim, Mi-Kyeong Kim, Sang-Heon Cho, Suk-Il Chang, Kyung-up Min, Kyung-up Min, Alyn Morice
A543 Elevated Airway CD45RO Memory Cells in Wheezing Children with Lower Respiratory Infection
Jungi Choi, Yusok Han, Jin-Sung Park, Eunmi Kwon, Chang-Keun Kim
A544 Quality of Life in Obese Children with or without Atopic Disease
Gartika Sapartini
A545 Relation of Human microRNA in Sputum of Asthma with Influenza A Virus Infection-Induced Exacerbation
Ji-Na Kim, Seungwoo Shin, Hun Soo Chang, Eun-Young Shim, Ji Ah Jun, Hyeonju Lee, Jong-Sook Park, Choon-Sik Park
A546 Aeropolinologic Monitoring and Distribution of Allergoallergens in Western Georgia
Revaz Sepiashvili, Darejan Khachapuridze, Sofio Gamkrelidze, Manana Chikhladze
A547 Extracorporeal Membrane Oxygenation As Emergency Treatment for Patients with Near-Fatal Status Asthmaticus
Seung-Eun Lee, Yun-Seong Kim, Doo-Soo Jeon, Woo-Hyun Cho, Hye-Ju Yeo, Seong-Hoon Yoon, Seung-Hyun Kim
A548 Relationship of S100calcium Binding Protein A9 with Neutophilic Inflammation in Murine Asthma Model
Taehyeong Lee, Hyun Ji Song, Choon-Sik Park, Ji Ah Jun, Jong-Sook Park
A549 Whole-Exome Sequencing of Aatopic Dermatitis in Korean Childhood
Dankyu Yoon, Yeon-Seop Kim, Woo-Sung Chang, Mi-Jin Kang, Soo-Jong Hong, Jeom-Kyu Lee, Eun-Jin Kim
A550 A Case of Generalized Molluscum Contagiosum in an Adult Patient with Severe Atopic Dermatitis
Minkee Park
A551 Discovery of Putative Macadamia Nut Allergens By Patient IgE Binding and a Label-Free Shotgun Proteomics Approach
Nanju Alice Lee, Johanna Rost, Sridevi Muralidharan, Dianne Campbell, Sam Mehr
A552 Anti-FcÎμri Antibody Inhibits Allergic March in Mice By Suppressing Th17 Pathway Via Suppression of FcÎμri-Mediated Mast Cells Activation
Seung-Hwa Lee, Seon-Joo Yoon, Ha-Jung Kim, Eun Lee, Song-I Yang, Young-Ho Jung, Ho-Sung Yu, Hee-Suk Kim, Yeon Hee Park, So-Yeon Lee, Jun-Sung Park
A553 Clinical Characteristics and the Associated Factors of ATG Hypersensitivity Reaction
Ha Kyeong Won, Min-Koo Kang, Sung Do Moon, Byung-Keun Kim, Ju-Young Kim, Sang-Heon Cho, Hye-Ryun Kang, Ji-Su Shim, Soo Jie Chung
A554 Reference Value and Utility of Total Serum Immunoglobulin E in Korean Schoolchildren
Jaehee Choi, Kangmo Ahn, Kwanghoon Kim, Jihyun Kim, Jiyoung Lee
A555 Two-Step Prescreening Skin Testing May be Useful for Reducing Immediate Hypersensitivity Reaction to Nonionic Contrast Media: Results of 7-Year Period in a Secondary Hospital
Bo Bae Park, In Young Nho, Chang-Han Park, Jang Min Kim, Suk-Il Chang
A556 Prevalence of Allergic Sensitization in Patients with Allergy Rhinitis; Gwangju, Jeonnam State Study
Sun Kyung Kim, Hyung Chae Yang, Kwang Il Nam
A557 Analysis of IgE Binding Components of Walnut in Korean Children Effect of Cooking Methods on the Allergenicity of Walnut Proteins
Jeongmin Lee, Jeongmin Lee, Sooyoung Lee, Kyunguk Jeong, Se-Ah Jeon
A558 Assessment of Autonomic Nervous Function in Subjects with Cholinergic Urticaria Associated with Acquired Idiopathic Generalized Anhidrosis
Midori Fujiwara, Shoko Shindo, Hiroyuki Murota, Mayuko Tahara, Aya Takahashi, Ichiro Katayama
A559 Interleukin 1 Beta in Sputum of Patients with Asthma: Relation with Airway Obstruction and Neutrophilc Inflammation
Jae Woo Jung, Hyun Ji Song, Taehyeong Lee, An-Soo Jang, Jong-Sook Park, Hun Soo Chang, Choon-Sik Park, Byoung Whui Choi
A560 Interleukin 8 in Sputum of Patients with Asthma: Relation with Neutrophilc Inflammation and Exacerbation
Min-Hye Kim, Da-Jeong Bae, Hyun Ji Song, Taehyeong Lee, Ji Ah Jun, Jong-Sook Park, An-Soo Jang, Hun Soo Chang, Young Joo Cho, Choon-Sik Park
A561 Prostaglandin E2 and Transforming Growth Factor-Î2 Play a Critical Role in Suppression of Allergic Airway Inflammation By Adipose-Derived Stem Cells
Sue Jean Mun
A562 Inhalation of Fine Particles Kill Alveolar Macrophages to Release IL-1alpha That Promote Inducible Bronchus-Associated Lymphoid Tissue (iBALT) Formation
Etsushi Kuroda, Koji Ozasa, Ken Ishii
A563 Association Between Smoking and Allergic Diseases in the Korean Adult General Population
Sunmi Kim, Gyeong-Hun Park
A564 Relationship of S100 Calcium Binding Protein A9 with Inflammasome Activation in Murine Asthma Model
Hyun Ji Song, Taehyeong Lee, Ji Ah Jun, Hun Soo Chang, Jong-Sook Park, Choon-Sik Park
A565 Cluster Analysis of Asthma Phenotypes to Predict Exacerbation in Korean Population
Mi-Ae Kim, Seungwoo Shin, Jong-Sook Park, Hun Soo Chang, You Sook Cho, Hae-Sim Park, Choon-Sik Park
A566 Effect of AG490 on the Expression of TH17 CELLS and Tregs in the MOUSE MODEL of Neutrophilic Asthma
Zhang Min
A567 Association Between the Clinical Characteristics and Disease Severity in Hospitalized Bronchiolitis Patients Younger Than Two Years Old
Seo Hee Yoon, In Suk Sol, Young a Park, Yoon Hee Kim, Min Jung Kim, Kyung Won Kim, Myung Hyun Sohn, Kyu-Earn Kim
A568 Comparison Between House Dust Mite and Aspergillosis Sensitization in Patients with High Level of Tige
Wu Shiquan
A569 The Prevalence of Metal Allergy in the Patients with Orthodontic Appliance
Yongwon Lee, Hana Bak
A570 Component Resolved Diagnosis and Single Nucleotide Polymorphism Analyses: Towards the Development of Specific Immunotherapy for Allergy
Maricar Wisco Ching, John Donnie Ramos
A571 Clinical Features of Anaphylaxis Caused By Peanut, Tree Nuts and Seeds in Children and Adolescents: Multi-Center Study with 126 Patients
Kyunguk Jeong, Sooyoung Lee, Kangmo Ahn, Myung Hyun Sohn, Kyung Won Kim, So-Yeon Lee, Tae Won Song, Youhoon Jeon, Jihyun Kim, Taek Ki Min, Kyu-Earn Kim, Bok-Yang Pyun, Hyeon-Jong Yang, Hae Ran Lee, Youngmin Ahn, Ji-Won Kwon, Dae Hyun Lim, Jeong Hee Kim, Dongin Suh, Hyung Young Ki
A572 A Report of Two Cases of Anaphylaxis Caused By Perilla Seed in Children
Kyunguk Jeong, Byeong Sub Park, Sooyoung Lee, Se-Ah Jeon, Kyu Jung Park
A573 Prenatal Fine Particulate Matter Affects Wheezing in Children with TLR4 Polymorphism: Cocoa Study
Song-I Yang, Eun Lee, Hyun-Ju Cho, Young-Ho Kim, Mi-Jin Kang, Yean Jung Choi, Kil Yong Choi, Youn Ho Shin, Kangmo Ahn, Kyung Won Kim, Byoung-Ju Kim, So-Yeon Lee, Eun-Jin K
A574 Intensified B Lymphocyte Depletion (IBLD) without Immunosuppressive Maintenance Treatment As a Rescue Therapy in Refractory Lupus Nephritis (LN): a 4-Year Observation.
Roccatello Dario
A575 Relationship Between Th17 Cells and Neutrophilic Airway Inflammation in Childhood Neutrophilic Asthma
Jing Liao
A576 Clinical Applications of Impulse Oscillometry in Asthma Management after Exacerbation in Preschool Children
Yong Feng, Yunxiao Shang
A577 Contact Allergy to Sodium Sulfite and Its Relationship to Facial Cosmetic Contact Dermatitis
Yongwon Lee, Hana Bak
A578 Effect of Exposure to Air Pollution on Asthma and Lung Function Development
Hyung Young Kim, Byoung-Ju Kim, Ji-Won Kwon, Ju-Hee Seo, Eun Lee, So-Yeon Lee, Song-I Yang, Young-Ho Jung, Hyo-Bin Kim, Ho-Jang Kwon, Hee Ju Park
A579 Role and Relational Mechanism of AG490 in Airwayinflammation in the Mouse Model of Neutrophilic Asthma
Zhang Min, Nong Guang-Min, Jiang Min
A580 Incidence of Adverse Reaction to Radioconstrast Media in a Single Tertiary Hospital
Gyu Young Hur, Eun Jung Sim, Sora Yoon, Juwhan Choi, Junga Kim, Jae Keom Sim, Jee Youn Oh
A581 Cow’s Milk Oral Food Challenge: Clinical and Laboratory Features in Korean Children
Kyunguk Jeong, Byeong Sub Park, Jeong-Min Lee, Sooyoung Lee, Eunjae Cheon, Youngjoo Na, Kyu Jung Park, Eunjoo Lee
A582 Validation of the Red Maple Trials Allergen Challenge Theatre for Ragweed Pollen Challenge
William Yang, Suzanne Kelly, Rob Perrins, Jimmy Yang
A583 Preliminary Evaluation of the Red Maple Trials Allergen Challenge Theatre for Grass Pollen
William Yang, Suzanne Kelly, Rob Perrins, Jacob Karsh, Jimmy Yang
A584 The Association Between Tobacco and the Risk of Asthma in Urban and Rural Children in San Francisco, Argentina
Hector Badellino, Alvaro Teijeiro, Mabel Cuello, Marilyn Urrutia Pereira, Gustavo Egues
A585 The Prevalence of Allergic Rhinitis in University Students in Manisa
Ayse Aktas
A586 Allergen Sensitization in Zimbabwean Children with Atopic Dermatitis
Jin-Kyong Chun, Hilda Angela Mujuru, Elopy N Sibanda
A587 Vitamin D Insufficiency in Asthmatic Patients
Andreea Ioana Popescu, Raluca Greblescu
A588 The Prevalence of Hypersensitivity Reactions Against Drugs Among University Students.
Suheyla Rahman, Ayse Aktas
A589 Sublingual Immunotherapy Among Problematic Patients, Suffering from Allergic Rhinitis.
Nataly Tataurshchikova
A590 A Novel Biomarker for Wheezing and Atopy in Early Infancy
Eishika Dissanayake, Yuzaburo Inoue, Naoki Shimojo, Taiji Nakano
A591 Prognostic Factors for Atopic Dermatitis in Spontaneously Born Babies from Low Socioeconomic Background
Conny Tanjung
A592 Higher IgE Antibody Levels Mediate Anti-Cancer Immunity in Transgenic KN1 Hyper-IgE Mice
Erika Jensen-Jarolim, Judit Fazekas, Josef Singer, Anna Lukschal, Reinhard Horvat, Gertrude Achatz-Straussberger, Gernot Achatz
A593 Fructooligosaccharides Intake during Pregnancy and Lactation Increases Gut Bifidobacterium and IL-27 in Breast Milk
Yuji Fujita, Shuji Ikegami, Yoshitaka Nakamura, Yuzaburo Inoue, Naoki Shimojo, Yoichi Kohno, Shuichi Suzuki, Naoko Ozawa, Takayuki Kubota, Ken Nonaka, Osamu Ohara, Kentaro Masuda
A594 Effect of Nintedanib on Asthma in Mouse Model
Chin Kook Rhee, Sook Young Lee, Hwa Young Lee, Hea Yon Lee, Ji Young Kang, Sei Won Kim, Soon Seog Kwon, Young Kyoon Kim
A595 Delayed Contrast Media Hypersensitivity after Coronary Angiography
Gun-Woo Kim, Ju-Young Kim, Sang-Heon Cho, Hye-Ryun Kang, Hyo-Soo Kim, Jung Gyu Han, Jin Lee, Ji Young Lee, Ji Young Go, So Jung Park
A596 Gene Expression Profiling in Patients with Chronic Idiopathic Urticaria Reveals Unique Gene Signature Distinct from Healthy Controls
Julie Kim-Chang, Cassandra Love, Patricia Lugar
A597 Failure to Recognize Lymphopenia in Newborn Leads to Undetectable Primary Immunodeficiency
Endah Citraresmi
A598 The Concordance Between Lung Function Test and Indonesian Version of Childhood Asthma Control Test (CACT)
Nastiti Kaswandani, Cynthia Utami, Mardjanis Said
A599 Synergistic Interaction Between Bronchiolitis and PM10 Is Modified By IL-13 Polymorphism on Asthma Development: Replication from Cheer Study
Young-Ho Jung, Song-I Yang, Byoung-Ju Kim, Ji-Won Kwon, Hwan-Cheol Kim, Jong-Han Leem, Ju-Hee Seo, Hyung Young Kim, So-Yeon Lee, Ho-Jang Kwon, Hyo-Bin Kim, Hyun-Ju Cho
A600 The Transcription Factor Ehf Is Involved in TGF-b-Induced Suppression of Fceri and c-Kit Expression and Fceri-Mediated Activation in Mast Cells
Susumu Yamazaki, Nobuhiro Nakano, Asuka Honjoh, Eisuke Inage, Yosuke Baba, Yoshikazu Ohtsuka, Toshiaki Shimizu
A601 The Follow up of the Potential Immunosuppressant Effects of Marijuana (MJA)
Ishaq M, Sameera MI Khan, Imran Khan, Sabeen Khan
A602 Risk Factors of Allergen Sensitization at 3 Years: Results from the Gusto Study
Evelyn Xiu Ling Loo, Anne Goh, Oon Hoe Teoh, Yiong Huak Chan, Seang Mei Saw, Kenneth Kwek, Peter D Gluckman, Keith M Godfrey, Hugo Van Bever, Yap Seng Chong, Bee Wah Lee, Lynette Shek, Alison Joanne Lee
A603 IL-6 Blockade As a Steroid-Sparing Treatment for Rhupus Patients
Daniela Rossi
A604 Examination of Late Pulmonary Toxicity in Children Treated for Malignancies
Agnes Nemeth
A605 Technical Validation of the Repurposing of a Personal Particle Sampler to Determine House Dust Mite Exposure in the Ambient Air
Torsten Sehlinger, Karl-Christian Bergmann, Frank Goergen
A606 Zinc Deficiency in Children with Severe Atopic Dermatitis: More Common Than Generally Thought
Mohammad S. Ehlayel, Abdul Bari Bener
A607 Strong Association Between HLA-B*5801 Allele and Allopurinol – Induced Severe Cutaneous Adverse Reactions in Vietnamese
Hieu Chi Chu, Nga Thi Quynh Do, Dinh Van Nguyen, Ha Thi Thu Nguyen, Huong Thi Minh Le, Sheryl Van Nunen, Christopher Vidal, Suran Fernando
A608 Successful Rapid Desensitization to Glatiramer Acetate: Report of 2 Cases
Fotis Psarros, Ekaterini Syrigou, Ekaterini Politi, Spyridon Chrysoulakis
A609 Asthma Exacerbations Seasonal Variation in Two Perennial Phenotypes during Twenty Years (1995-2014): House Dust Mite Monosensitized and Non Atopic Patients
Dimitrios Vourdas, Konstantinos Petalas
A610 Occupational Allergy to Fungal Spores Among the Farmers of Paddy Fields in West Bengal, India: An Aeromycological and Immunological Approach
Mouli SAHA, Kashinath Bhattacharya
A611 Study of Efficacy of Sublingual Immunotherapy (SLIT) in Cases of Severe Persistent Allergic Rhinitis
Subir Jain
A612 Mesenchymal Stem Cells Suppress Lung Inflammation and Airway Remodeling in Chronic Asthma Rat Model Via PI3K/Akt Signaling Pathway Mesenchymal Stem Cells Suppress Lung Inflammation and Airway Remodeling in Chronic Asthma Rat Model Via PI3K/Akt Signaling
Xiaolian Song, Haiyan Lin
A613 Development of Allergen ELISA Kits for Dust Mites, Pollen, and Pet Dander
Kyohei Nishikawa, Takashi Shimada, Hiroshi Yasueda, Tadao Enomoto, Daisuke Aizawa, Takayoshi Kobayashi
A614 Yoga As a Lifestyle Modification to Improve the Quality of Life in Smokers with Allergic Rhinitis
Chellaa R
A615 Study of Incidence of Severe Persistent Allergic Rhinitis in Different Age Groups,Sex Prevalance and Type of Allergen” Aeroallergen or Food Allergen” Responsible for Severe Persistent Allergic Rhinitis in Central India
Subir Jain
A616 Causative Allergens in Cases of Severe Persistent Allergic Rhinitis in Central India
Subir Jain
A617 Atopic Dermatitis: A New Data on the Mechanisms of Chronic Pruritus
Marina Yudina
A618 The Efficacy and Safety of Peanut Oral Immunotherapy in High-Dose with Predicting Factors
Ishaq M, Sameera MI Khan, Imran Khan, Sabeen Khan
A619 Evaluation of Long-Term Prognosis and Topical Corticosteroid Usage after One Year of Proactive Treatment for Children with Moderate-to-Severe Atopic Dermatitis
Mayako Saito
A620 Allergy Symptoms in the First Two Months of Life
Nurul Iman Nilam Sari
A621 Factors Related to the Seasonal Variation of Allergic Rhinitis
Jae Young Kim, Jaechul Song, Inah Kim, Kyeong Joon Lee, Soo Jin Park, Soo Yong Roh
A622 Allergic Risk Survey in Lao Children at out-Patient Department, Children’s Hospital, Vientiane Capital, Lao PDR
Somxay Billamay
A623 Correlation Between Food Allergy, Aeroinhalant Allergy, Allergic Rhinitis, Atopic Dermatitis, and Acute Upper Respiratory Tract Infections and Levels of Severity of Asthma in Pediatric Medicine Department Saiful Anwar Hospital Indonesia
Muchammad Fahrul Udin
A624 Comparative Study of Pine, Oak, and Ginkgo Pollen Counts in Korea during Last Four Years
Mae Ja Han, Jae-Won Oh, Kyu Rang Kim, Baek-Jo Kim
A625 Effectiveness of Allergy-Test Directed Elimination Diets in Eosinophilic Esophagitis
Jorge A Mazza, Jason Kangeun Ko, David JT Huang
A626 Comparison of Cut-Off Values and Probability Curves for Egg Specific IgE in Diagnosis of Egg Allergy in Young Children
Kanae Furuya, Keigo Kainuma, Takahiro Ito, Mizuho Nagao, Takao Fujisawa, Junya Hirayama, Yu Kuwahara
A627 A Case of Persistent Atopic Dermatitis Associated with Parasitic Infection
Rosanna Qualizza, Cristoforo Incorvaia, Anna Maraschini
A628 Aeroallergenic Profile of Indoor Allergens and Their Clinical Relevance in Allergy and Asthma Patients in Saudi Arabia
Syed Mohammed Hasnain, Abdulrahman Al-Frayh
A629 Oral Exposure to the Amino Acid Glycine Inhibits the Onset of Allergic Disorders
Anita Hartog, Jacqueline Bastiaans, Reinilde Loonstra, Lieke Rutten, Lucien Harthoorn, Jeroen Van Bergenhenegouwen, Johan Garssen, Johan Garssen
A630 Cough As a Key Symptom in Asthma, Allergic Rhinitis, COPD and Rhinosinusitis and Its Impact in Korea
Kwang-Ha Yoo, Sang-Heon Cho, AG Ghoshal, Abdul Razak Bin Abdul Muttalif, Horng- Chyuan Lin, Sanguansak Thanaviratananich, Shalini Bagga, Rab Faruqi, Santwona Baidya, Colman Taylor, De Yun Wang, Hae-Ryun Ahn, Soon-Kwan Hong, Jong-Woong Kim, Gui-Hyun Nam, Mee-Ja Kim, Jae-Kyoung Park
A631 Cysteine Protease Allergen Def f 1 Induces Th2 Cytokines in Mouse Bone Marrow Derived Basophils Via ERK and JNK Dependent Pathways
Myung-Hee Yi, Kyoung Yong Jeong, Ju-Yeong Kim, Tai-Soon Yong
A632 Novel Multiple Allergy Testing Kit Using Parallel Lines Array (PLA) Technology
Bum Joon Kim, Hs Joo, Kj Lim, Jae-Hyun Lee, Jung-Won Park, Kh Yoon, DS Choi
A633 Quantitative Rapid Kit for Human Immunoglobulin
Hanseung Joo, Bum Joon Kim, Kj Lim, MJ KIM, DS Choi, Kh Yoon
A634 Total IgE Measurement By Protia Allergy-Q: Comparison Study with Immunocap
Bum Joon Kim, Hanseung Joo, Woo Sang Jung, Kj Lim, DS Choi
A635 Prevalence and Risk Factors of Asthma Among Korean Farmers
Ji-Hoon Lee, Soon-Chan Kwon, Soo-Jin Lee, Soo Yong Roh, Hogil Kim, Kyeong Joon Lee
A636 Dietary Intake and Perceived Immune Status in Young Dutch Women
Aurora Van De Loo, Amanda Fernstrand, Johan Garssen, Joris Verster
A637 The Effects of Antihistamine Drugs on on-Road Driving Performance
Aurora Van De Loo, Johan Garssen, Joris Verster
A638 Grass Is Guilty: A Case of Anaphylactic Shock and Asthmatic Status in the Same Time in an Individual
Jasmina Golez
A639 Cyclic Gamp-AMP(cGAMP) Induces Allergic Inflammation
Koji Ozasa, Etsushi Kuroda, Ken Ishii, Ken Ishii
A640 Role of Omalizumab in the Setting of Recalcitrate Dermatitis with Extremely Elevated IgE Levels
Muhammad Imran, Selina Gierer, John Martinez
A641 Follow-up Study on the Natural History of Prawn Allergy
Lydia Wong, Bee Wah Lee, Gaik Chin Yap, Genevieve Llanora, Bernard Thong, Lynette Shek
A642 Protein-Losing Dermopathy Impairing Growth in Children with Severe Atopic Dermatitis
Mohammad S. Ehlayel, Ashraf Soliman
A643 Airways Assessment of Aged Nursing Homes Residents
Pedro Martins, João Marques, Joana Gomes-Belo, Teresa Palmeiro, Iolanda Caires, Joana Belo, Maria Amália Botelho, Paula Leiria-Pinto, Nuno Neuparth
A644 Use of Skin Prick Test, Specific IgE to Shrimp and Rpen a1 to Determine Clinical Reaction to Shrimp in Area with High Prevalence of House Dust Mite Sensitization
Narissara Suratannon, Jaichat Mekaroonkamol, Jarungchit Ngamphaiboon, Piyawadee Lertchanaruengrith, Pantipa Chatchatee
A645 Identification of Specific IgE-Binding Proteins in Tree of Heaven (Ailanthus altissima) Pollen
Gholamali Kardar, Ahmad Majd, Youcef Shahali, Farrokh Ghahremaninejad, Zahra Pourpak, Fateme Mousavi
A646 Allergy Immunotherapy Well Tolerated in Children
Mahnaz Sadeghi-Shabestari
A647 Steinert (DM1) Patients Have IgG1 Deficiency and Should be Screened for Immune Deficiency
K. Van Bilsen, O. Manusama, W.a. Dik, M. Van Der Burg, V. H. J. Van Der Velden, V.a.S. H. Dalm, P. M. Van Hagen
A648 The Change of Serous Sige and Three Evaluation before and after Sublingual Immunotherapy with Dermatophagoides Farinae for Persistent Allergic Rhinitis
Yongping Liu
A649 Garlic Extracts Reduce Histamine-Induced Proliferation and Migration of Human Asthmatic Bronchial Smooth Muscle Cells
Yi Yeong Jeong
A650 A Case of Occupational Contact Dermatitis Caused By N-Acetylcysteine
Ji Hye Kim, Moon Gyeong Yoon, Young Min Ye, Yoo Seob Shin, Ga Young Ban, Hae-Sim Park, Hye Min Jung
A651 The Association Between Pollen Change and Asthma Attacks
Soo Yong Roh, Jaechul Song, Ji-Hoon Lee, Hogil Kim, Jae Young Kim, Kyeong Joon Lee
A652 Incidence of Emergency Department Visits and Hospitalizations for Asthma Exacerbations during the Lunar Month in Singapore
Lydia Wong, Mohana Rajakulendran, Haripriya Santhanam, Lynette Shek, Tow Keang Lim
A653 The Prevalence of Positive Reaction for Skin Prick Test in Korean Farmers and Its Occupational Risk Factors
Hogil Kim, Soo-Jin Lee, Ji-Hoon Lee, Soo Yong Roh, Soon-Chan Kwon
A654 Drug Allergy in Children: A Three-Years Experience at Dr. Kariadi Hospital Semarang Indonesia
Wistiani, Galuh H, Ani Wistiani
A655 The Identification of Morphology, Structure and Study of Seasonal Variation of Airborne Fraxinus Excelsior Pollen Grains in the Tehran
Gholam Ali Kardar, Maryam Sharifshoushtari, Ahmad Majd, Taher Nejadsattari, Zahra Pourpak, Mostafa Moin
A656 Sublingual Immunotherapy in Elderly Rhinitis Patients Sensitized to House Dust Mites
Ji Hye Kim, Daehong Seo, Young Min Ye, Hae-Sim Park, Jung-Won Park, Jae-Hyun Lee, Yoo Seob Shin
A657 Healthy Ageing Research Center (HARC) As a Platform for Multidisciplinary Approaches to Respiratory Research in the Elderly
Marek L. Kowalski, Aleksandra Wardzynska, Marcin Kurowski, Malgorzata / Ewa Pawelczyk, Adam Wysokinski, Iwona Kloszewska, Janina Grzegorczyk, Wojciech Piotrowski, Joanna Makowska
A658 Estimation of Cases of Work-Related Asthma Using Capture-Recapture Methods
Soon-Chan Kwon, Jaechul Song, Yong-Kyu Kim
A659 Primary School Students’ Parents Reported ISAAC Questionnaire in a Low Income Area of Ankara
Ilknur Bostanci, Zeynep Sengul Emeksiz, Aysegul Ertugrul, Serap Ozmen, Soner Sahin
A660 Usefulness of PC20 Adenosine Monophosphate in Diagnosis and Treatment in Bronchial Asthma
Sang-Ha Kim, Myoung Kyu Lee, Won Yeon Lee, Suk Joong Yong, Seok Jeong Lee, Ye-Ryung Jung
A661 S100 Calcium Binding Protein A9 in Sputum of Patients with Steroid Naive Asthma: Relation with Airway Obstruction and Nneutrophilc Inflammation
Myung Shin Kim, Jong-Sook Park, An-Soo Jang, Choon-Sik Park
A662 Risk Factor Asthma in Pediatric Pneumonia Patients
Diah Asri Wulandari, Cissy Kartasasmita
A663 Prevalence and Risk Factors of Childhood Asthma and Allergic Disease at Exposed Area By Emission of Cement Padang Factory
Finny Fitry Yani, Rizanda Machmud, Dhina Lydia Lestari
A664 Association Between Serum Level of 25-Hydroxyvitamin D with Atopic Dermatitis Occurrence and Severity in Children
Rusdi Rusdi, Yurmalina Yurmalina, Eryati Darwin
A665 Thiol-Disulfide Balance in Children with Atopic Dermatitis
Ilknur Bostanci, Gulin Karacan, Nazli Ercan, Asuman Colak, Murat Alisik, Gulay Basarir, Ozcan Erel
A666 Recurrent Mouth Ulsers Caused By Braces after Developing a Nickel Allergy in Children
Ilknur Bostanci, Yasemin Keskin
A667 Anaphylactic Reaction to Famotidine with Pheniramine Hypersensitivity
Ilkay Koca Kalkan
A668 Novel Transcriptomic and Immunoproteotomic Approaches in Identifying Cross-Reactive Allergens Between Crustacean and Molluscs
Andreas/Ludwig Lopata, Kyall Zenger, Roni Nugraha, Sandip Kamath
A669 Pollen Season and Climate Change in the Continental United States (CONUS)
Leonard Bielory, Panos Georgopoulos, Yong Zhang, Wheat Mi, Ting Cai
A670 Differences of Change in Der p IgG4 and CD4+CD25+FoxP3+ Treg Cells Between Sublingual and Subcutaneous Immunotherapy with House Dust Mite in Chinese Patients with Allergic Rhinitis
MO Xian, Jing Li, Mulin Feng
doi:10.1186/s40413-016-0096-1
PMCID: PMC4896250
2.  Clinical Utility of Vitamin D Testing 
Executive Summary
This report from the Medical Advisory Secretariat (MAS) was intended to evaluate the clinical utility of vitamin D testing in average risk Canadians and in those with kidney disease. As a separate analysis, this report also includes a systematic literature review of the prevalence of vitamin D deficiency in these two subgroups.
This evaluation did not set out to determine the serum vitamin D thresholds that might apply to non-bone health outcomes. For bone health outcomes, no high or moderate quality evidence could be found to support a target serum level above 50 nmol/L. Similarly, no high or moderate quality evidence could be found to support vitamin D’s effects in non-bone health outcomes, other than falls.
Vitamin D
Vitamin D is a lipid soluble vitamin that acts as a hormone. It stimulates intestinal calcium absorption and is important in maintaining adequate phosphate levels for bone mineralization, bone growth, and remodelling. It’s also believed to be involved in the regulation of cell growth proliferation and apoptosis (programmed cell death), as well as modulation of the immune system and other functions. Alone or in combination with calcium, Vitamin D has also been shown to reduce the risk of fractures in elderly men (≥ 65 years), postmenopausal women, and the risk of falls in community-dwelling seniors. However, in a comprehensive systematic review, inconsistent results were found concerning the effects of vitamin D in conditions such as cancer, all-cause mortality, and cardiovascular disease. In fact, no high or moderate quality evidence could be found concerning the effects of vitamin D in such non-bone health outcomes. Given the uncertainties surrounding the effects of vitamin D in non-bone health related outcomes, it was decided that this evaluation should focus on falls and the effects of vitamin D in bone health and exclusively within average-risk individuals and patients with kidney disease.
Synthesis of vitamin D occurs naturally in the skin through exposure to ultraviolet B (UVB) radiation from sunlight, but it can also be obtained from dietary sources including fortified foods, and supplements. Foods rich in vitamin D include fatty fish, egg yolks, fish liver oil, and some types of mushrooms. Since it is usually difficult to obtain sufficient vitamin D from non-fortified foods, either due to low content or infrequent use, most vitamin D is obtained from fortified foods, exposure to sunlight, and supplements.
Clinical Need: Condition and Target Population
Vitamin D deficiency may lead to rickets in infants and osteomalacia in adults. Factors believed to be associated with vitamin D deficiency include:
darker skin pigmentation,
winter season,
living at higher latitudes,
skin coverage,
kidney disease,
malabsorption syndromes such as Crohn’s disease, cystic fibrosis, and
genetic factors.
Patients with chronic kidney disease (CKD) are at a higher risk of vitamin D deficiency due to either renal losses or decreased synthesis of 1,25-dihydroxyvitamin D.
Health Canada currently recommends that, until the daily recommended intakes (DRI) for vitamin D are updated, Canada’s Food Guide (Eating Well with Canada’s Food Guide) should be followed with respect to vitamin D intake. Issued in 2007, the Guide recommends that Canadians consume two cups (500 ml) of fortified milk or fortified soy beverages daily in order to obtain a daily intake of 200 IU. In addition, men and women over the age of 50 should take 400 IU of vitamin D supplements daily. Additional recommendations were made for breastfed infants.
A Canadian survey evaluated the median vitamin D intake derived from diet alone (excluding supplements) among 35,000 Canadians, 10,900 of which were from Ontario. Among Ontarian males ages 9 and up, the median daily dietary vitamin D intake ranged between 196 IU and 272 IU per day. Among females, it varied from 152 IU to 196 IU per day. In boys and girls ages 1 to 3, the median daily dietary vitamin D intake was 248 IU, while among those 4 to 8 years it was 224 IU.
Vitamin D Testing
Two laboratory tests for vitamin D are available, 25-hydroxy vitamin D, referred to as 25(OH)D, and 1,25-dihydroxyvitamin D. Vitamin D status is assessed by measuring the serum 25(OH)D levels, which can be assayed using radioimmunoassays, competitive protein-binding assays (CPBA), high pressure liquid chromatography (HPLC), and liquid chromatography-tandem mass spectrometry (LC-MS/MS). These may yield different results with inter-assay variation reaching up to 25% (at lower serum levels) and intra-assay variation reaching 10%.
The optimal serum concentration of vitamin D has not been established and it may change across different stages of life. Similarly, there is currently no consensus on target serum vitamin D levels. There does, however, appear to be a consensus on the definition of vitamin D deficiency at 25(OH)D < 25 nmol/l, which is based on the risk of diseases such as rickets and osteomalacia. Higher target serum levels have also been proposed based on subclinical endpoints such as parathyroid hormone (PTH). Therefore, in this report, two conservative target serum levels have been adopted, 25 nmol/L (based on the risk of rickets and osteomalacia), and 40 to 50 nmol/L (based on vitamin D’s interaction with PTH).
Ontario Context
Volume & Cost
The volume of vitamin D tests done in Ontario has been increasing over the past 5 years with a steep increase of 169,000 tests in 2007 to more than 393,400 tests in 2008. The number of tests continues to rise with the projected number of tests for 2009 exceeding 731,000. According to the Ontario Schedule of Benefits, the billing cost of each test is $51.7 for 25(OH)D (L606, 100 LMS units, $0.517/unit) and $77.6 for 1,25-dihydroxyvitamin D (L605, 150 LMS units, $0.517/unit). Province wide, the total annual cost of vitamin D testing has increased from approximately $1.7M in 2004 to over $21.0M in 2008. The projected annual cost for 2009 is approximately $38.8M.
Evidence-Based Analysis
The objective of this report is to evaluate the clinical utility of vitamin D testing in the average risk population and in those with kidney disease. As a separate analysis, the report also sought to evaluate the prevalence of vitamin D deficiency in Canada. The specific research questions addressed were thus:
What is the clinical utility of vitamin D testing in the average risk population and in subjects with kidney disease?
What is the prevalence of vitamin D deficiency in the average risk population in Canada?
What is the prevalence of vitamin D deficiency in patients with kidney disease in Canada?
Clinical utility was defined as the ability to improve bone health outcomes with the focus on the average risk population (excluding those with osteoporosis) and patients with kidney disease.
Literature Search
A literature search was performed on July 17th, 2009 using OVID MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, EMBASE, the Cumulative Index to Nursing & Allied Health Literature (CINAHL), the Cochrane Library, and the International Agency for Health Technology Assessment (INAHTA) for studies published from January 1, 1998 until July 17th, 2009. Abstracts were reviewed by a single reviewer and, for those studies meeting the eligibility criteria, full-text articles were obtained. Reference lists were also examined for any additional relevant studies not identified through the search. Articles with unknown eligibility were reviewed with a second clinical epidemiologist, then a group of epidemiologists until consensus was established. The quality of evidence was assessed as high, moderate, low or very low according to GRADE methodology.
Observational studies that evaluated the prevalence of vitamin D deficiency in Canada in the population of interest were included based on the inclusion and exclusion criteria listed below. The baseline values were used in this report in the case of interventional studies that evaluated the effect of vitamin D intake on serum levels. Studies published in grey literature were included if no studies published in the peer-reviewed literature were identified for specific outcomes or subgroups.
Considering that vitamin D status may be affected by factors such as latitude, sun exposure, food fortification, among others, the search focused on prevalence studies published in Canada. In cases where no Canadian prevalence studies were identified, the decision was made to include studies from the United States, given the similar policies in vitamin D food fortification and recommended daily intake.
Inclusion Criteria
Studies published in English
Publications that reported the prevalence of vitamin D deficiency in Canada
Studies that included subjects from the general population or with kidney disease
Studies in children or adults
Studies published between January 1998 and July 17th 2009
Exclusion Criteria
Studies that included subjects defined according to a specific disease other than kidney disease
Letters, comments, and editorials
Studies that measured the serum vitamin D levels but did not report the percentage of subjects with serum levels below a given threshold
Outcomes of Interest
Prevalence of serum vitamin D less than 25 nmol/L
Prevalence of serum vitamin D less than 40 to 50 nmol/L
Serum 25-hydroxyvitamin D was the metabolite used to assess vitamin D status. Results from adult and children studies were reported separately. Subgroup analyses according to factors that affect serum vitamin D levels (e.g., seasonal effects, skin pigmentation, and vitamin D intake) were reported if enough information was provided in the studies
Quality of Evidence
The quality of the prevalence studies was based on the method of subject recruitment and sampling, possibility of selection bias, and generalizability to the source population. The overall quality of the trials was examined according to the GRADE Working Group criteria.
Summary of Findings
Fourteen prevalence studies examining Canadian adults and children met the eligibility criteria. With the exception of one longitudinal study, the studies had a cross-sectional design. Two studies were conducted among Canadian adults with renal disease but none studied Canadian children with renal disease (though three such US studies were included). No systematic reviews or health technology assessments that evaluated the prevalence of vitamin D deficiency in Canada were identified. Two studies were published in grey literature, consisting of a Canadian survey designed to measure serum vitamin D levels and a study in infants presented as an abstract at a conference. Also included were the results of vitamin D tests performed in community laboratories in Ontario between October 2008 and September 2009 (provided by the Ontario Association of Medical Laboratories).
Different threshold levels were used in the studies, thus we reported the percentage of subjects with serum levels of between 25 and 30 nmol/L and between 37.5 and 50 nmol/L. Some studies stratified the results according to factors affecting vitamin D status and two used multivariate models to investigate the effects of these characteristics (including age, season, BMI, vitamin D intake, skin pigmentation, and season) on serum 25(OH)D levels. It’s unclear, however, if these studies were adequately powered for these subgroup analyses.
Study participants generally consisted of healthy, community-dwelling subjects and most excluded individuals with conditions or medications that alter vitamin D or bone metabolism, such as kidney or liver disease. Although the studies were conducted in different parts of Canada, fewer were performed in Northern latitudes, i.e. above 53°N, which is equivalent to the city of Edmonton.
Adults
Serum vitamin D levels of < 25 to 30 nmol/L were observed in 0% to 25.5% of the subjects included in five studies; the weighted average was 3.8% (95% CI: 3.0, 4.6). The preliminary results of the Canadian survey showed that approximately 5% of the subjects had serum levels below 29.5 nmol/L. The results of over 600,000 vitamin D tests performed in Ontarian community laboratories between October 2008 and September 2009 showed that 2.6% of adults (> 18 years) had serum levels < 25 nmol/L.
The prevalence of serum vitamin D levels below 37.5-50 nmol/L reported among studies varied widely, ranging from 8% to 73.6% with a weighted average of 22.5%. The preliminary results of the CHMS survey showed that between 10% and 25% of subjects had serum levels below 37 to 48 nmol/L. The results of the vitamin D tests performed in community laboratories showed that 10% to 25% of the individuals had serum levels between 39 and 50 nmol/L.
In an attempt to explain this inter-study variation, the study results were stratified according to factors affecting serum vitamin D levels, as summarized below. These results should be interpreted with caution as none were adjusted for other potential confounders. Adequately powered multivariate analyses would be necessary to determine the contribution of risk factors to lower serum 25(OH)D levels.
Seasonal variation
Three adult studies evaluating serum vitamin D levels in different seasons observed a trend towards a higher prevalence of serum levels < 37.5 to 50 nmol/L during the winter and spring months, specifically 21% to 39%, compared to 8% to 14% in the summer. The weighted average was 23.6% over the winter/spring months and 9.6% over summer. The difference between the seasons was not statistically significant in one study and not reported in the other two studies.
Skin Pigmentation
Four studies observed a trend toward a higher prevalence of serum vitamin D levels < 37.5 to 50 nmol/L in subjects with darker skin pigmentation compared to those with lighter skin pigmentation, with weighted averages of 46.8% among adults with darker skin colour and 15.9% among those with fairer skin.
Vitamin D intake and serum levels
Four adult studies evaluated serum vitamin D levels according to vitamin D intake and showed an overall trend toward a lower prevalence of serum levels < 37.5 to 50 nmol/L with higher levels of vitamin D intake. One study observed a dose-response relationship between higher vitamin D intake from supplements, diet (milk), and sun exposure (results not adjusted for other variables). It was observed that subjects taking 50 to 400 IU or > 400 IU of vitamin D per day had a 6% and 3% prevalence of serum vitamin D level < 40 nmol/L, respectively, versus 29% in subjects not on vitamin D supplementation. Similarly, among subjects drinking one or two glasses of milk per day, the prevalence of serum vitamin D levels < 40 nmol/L was found to be 15%, versus 6% in those who drink more than two glasses of milk per day and 21% among those who do not drink milk. On the other hand, one study observed little variation in serum vitamin D levels during winter according to milk intake, with the proportion of subjects exhibiting vitamin D levels of < 40 nmol/L being 21% among those drinking 0-2 glasses per day, 26% among those drinking > 2 glasses, and 20% among non-milk drinkers.
The overall quality of evidence for the studies conducted among adults was deemed to be low, although it was considered moderate for the subgroups of skin pigmentation and seasonal variation.
Newborn, Children and Adolescents
Five Canadian studies evaluated serum vitamin D levels in newborns, children, and adolescents. In four of these, it was found that between 0 and 36% of children exhibited deficiency across age groups with a weighted average of 6.4%. The results of over 28,000 vitamin D tests performed in children 0 to 18 years old in Ontario laboratories (Oct. 2008 to Sept. 2009) showed that 4.4% had serum levels of < 25 nmol/L.
According to two studies, 32% of infants 24 to 30 months old and 35.3% of newborns had serum vitamin D levels of < 50 nmol/L. Two studies of children 2 to 16 years old reported that 24.5% and 34% had serum vitamin D levels below 37.5 to 40 nmol/L. In both studies, older children exhibited a higher prevalence than younger children, with weighted averages 34.4% and 10.3%, respectively. The overall weighted average of the prevalence of serum vitamin D levels < 37.5 to 50 nmol/L among pediatric studies was 25.8%. The preliminary results of the Canadian survey showed that between 10% and 25% of subjects between 6 and 11 years (N= 435) had serum levels below 50 nmol/L, while for those 12 to 19 years, 25% to 50% exhibited serum vitamin D levels below 50 nmol/L.
The effects of season, skin pigmentation, and vitamin D intake were not explored in Canadian pediatric studies. A Canadian surveillance study did, however, report 104 confirmed cases1 (2.9 cases per 100,000 children) of vitamin D-deficient rickets among Canadian children age 1 to 18 between 2002 and 2004, 57 (55%) of which from Ontario. The highest incidence occurred among children living in the North, i.e., the Yukon, Northwest Territories, and Nunavut. In 92 (89%) cases, skin pigmentation was categorized as intermediate to dark, 98 (94%) had been breastfed, and 25 (24%) were offspring of immigrants to Canada. There were no cases of rickets in children receiving ≥ 400 IU VD supplementation/day.
Overall, the quality of evidence of the studies of children was considered very low.
Kidney Disease
Adults
Two studies evaluated serum vitamin D levels in Canadian adults with kidney disease. The first included 128 patients with chronic kidney disease stages 3 to 5, 38% of which had serum vitamin D levels of < 37.5 nmol/L (measured between April and July). This is higher than what was reported in Canadian studies of the general population during the summer months (i.e. between 8% and 14%). In the second, which examined 419 subjects who had received a renal transplantation (mean time since transplantation: 7.2 ± 6.4 years), the prevalence of serum vitamin D levels < 40 nmol/L was 27.3%. The authors concluded that the prevalence observed in the study population was similar to what is expected in the general population.
Children
No studies evaluating serum vitamin D levels in Canadian pediatric patients with kidney disease could be identified, although three such US studies among children with chronic kidney disease stages 1 to 5 were. The mean age varied between 10.7 and 12.5 years in two studies but was not reported in the third. Across all three studies, the prevalence of serum vitamin D levels below the range of 37.5 to 50 nmol/L varied between 21% and 39%, which is not considerably different from what was observed in studies of healthy Canadian children (24% to 35%).
Overall, the quality of evidence in adults and children with kidney disease was considered very low.
Clinical Utility of Vitamin D Testing
A high quality comprehensive systematic review published in August 2007 evaluated the association between serum vitamin D levels and different bone health outcomes in different age groups. A total of 72 studies were included. The authors observed that there was a trend towards improvement in some bone health outcomes with higher serum vitamin D levels. Nevertheless, precise thresholds for improved bone health outcomes could not be defined across age groups. Further, no new studies on the association were identified during an updated systematic review on vitamin D published in July 2009.
With regards to non-bone health outcomes, there is no high or even moderate quality evidence that supports the effectiveness of vitamin D in outcomes such as cancer, cardiovascular outcomes, and all-cause mortality. Even if there is any residual uncertainty, there is no evidence that testing vitamin D levels encourages adherence to Health Canada’s guidelines for vitamin D intake. A normal serum vitamin D threshold required to prevent non-bone health related conditions cannot be resolved until a causal effect or correlation has been demonstrated between vitamin D levels and these conditions. This is as an ongoing research issue around which there is currently too much uncertainty to base any conclusions that would support routine vitamin D testing.
For patients with chronic kidney disease (CKD), there is again no high or moderate quality evidence supporting improved outcomes through the use of calcitriol or vitamin D analogs. In the absence of such data, the authors of the guidelines for CKD patients consider it best practice to maintain serum calcium and phosphate at normal levels, while supplementation with active vitamin D should be considered if serum PTH levels are elevated. As previously stated, the authors of guidelines for CKD patients believe that there is not enough evidence to support routine vitamin D [25(OH)D] testing. According to what is stated in the guidelines, decisions regarding the commencement or discontinuation of treatment with calcitriol or vitamin D analogs should be based on serum PTH, calcium, and phosphate levels.
Limitations associated with the evidence of vitamin D testing include ambiguities in the definition of an ‘adequate threshold level’ and both inter- and intra- assay variability. The MAS considers both the lack of a consensus on the target serum vitamin D levels and assay limitations directly affect and undermine the clinical utility of testing. The evidence supporting the clinical utility of vitamin D testing is thus considered to be of very low quality.
Daily vitamin D intake, either through diet or supplementation, should follow Health Canada’s recommendations for healthy individuals of different age groups. For those with medical conditions such as renal disease, liver disease, and malabsorption syndromes, and for those taking medications that may affect vitamin D absorption/metabolism, physician guidance should be followed with respect to both vitamin D testing and supplementation.
Conclusions
Studies indicate that vitamin D, alone or in combination with calcium, may decrease the risk of fractures and falls among older adults.
There is no high or moderate quality evidence to support the effectiveness of vitamin D in other outcomes such as cancer, cardiovascular outcomes, and all-cause mortality.
Studies suggest that the prevalence of vitamin D deficiency in Canadian adults and children is relatively low (approximately 5%), and between 10% and 25% have serum levels below 40 to 50 nmol/L (based on very low to low grade evidence).
Given the limitations associated with serum vitamin D measurement, ambiguities in the definition of a ‘target serum level’, and the availability of clear guidelines on vitamin D supplementation from Health Canada, vitamin D testing is not warranted for the average risk population.
Health Canada has issued recommendations regarding the adequate daily intake of vitamin D, but current studies suggest that the mean dietary intake is below these recommendations. Accordingly, Health Canada’s guidelines and recommendations should be promoted.
Based on a moderate level of evidence, individuals with darker skin pigmentation appear to have a higher risk of low serum vitamin D levels than those with lighter skin pigmentation and therefore may need to be specially targeted with respect to optimum vitamin D intake. The cause-effect of this association is currently unclear.
Individuals with medical conditions such as renal and liver disease, osteoporosis, and malabsorption syndromes, as well as those taking medications that may affect vitamin D absorption/metabolism, should follow their physician’s guidance concerning both vitamin D testing and supplementation.
PMCID: PMC3377517  PMID: 23074397
3.  Skin Disorders Among Geriatric Population at a Tertiary Care Center in Uttarakhand 
Introduction
Ageing results in decline of normal functioning in all organ systems including skin. This predisposes the elderly persons to develop various skin ailments. A thorough knowledge of different diseases prevalent in this population in different geographic regions help the health care providers in better health care policy making.
Aim
This study was planned to know the common dermatological diseases prevalent in Uttarakhand region of India.
Materials and Methods
Hospital out patients records maintained in Department of Dermatology, Venereology & Leprosy were analysed and information regarding age, sex and diagnosis of patients were recorded. Descriptive statistics for prevalence of skin diseases in patients presenting to hospital were calculated.
Results
Out of the total 29,422 patients seen in dermatology department from August 2012 to 2014, 4.7% (1,380) were aged 60 years and above. Male to female ratio was 2:1. Erythemato-squamous disorders taken collectively constituted the major skin disorder seen in 38.9% patients. This was followed by infections and infestations (29.9%), senile pruritus (9.0%) and age related skin changes (3.7%). Benign neoplasms were seen in 1.1% patients followed by cutaneous malignancies in 0.8% and precancerous lesions in 0.4%. Fungal infections were the most common infections seen in 18% patients.
Conclusion
This study strengthens the opinion that infections, senile pruritus and eczema-dermatitis are the major dermatological disorders in elderly population.
doi:10.7860/JCDR/2016/17015.7500
PMCID: PMC4843367  PMID: 27134982
Ageing; Dermatoses; Pruritus; Senile
4.  Scabies Mites Alter the Skin Microbiome and Promote Growth of Opportunistic Pathogens in a Porcine Model 
Background
The resident skin microbiota plays an important role in restricting pathogenic bacteria, thereby protecting the host. Scabies mites (Sarcoptes scabiei) are thought to promote bacterial infections by breaching the skin barrier and excreting molecules that inhibit host innate immune responses. Epidemiological studies in humans confirm increased incidence of impetigo, generally caused by Staphylococcus aureus and Streptococcus pyogenes, secondary to the epidermal infestation with the parasitic mite. It is therefore possible that mite infestation could alter the healthy skin microbiota making way for the opportunistic pathogens. A longitudinal study to test this hypothesis in humans is near impossible due to ethical reasons. In a porcine model we generated scabies infestations closely resembling the disease manifestation in humans and investigated the scabies associated changes in the skin microbiota over the course of a mite infestation.
Methodology/Principal Findings
In a 21 week trial, skin scrapings were collected from pigs infected with S. scabies var. suis and scabies-free control animals. A total of 96 skin scrapings were collected before, during infection and after acaricide treatment, and analyzed by bacterial 16S rDNA tag-encoded FLX-titanium amplicon pyrosequencing. We found significant changes in the epidermal microbiota, in particular a dramatic increase in Staphylococcus correlating with the onset of mite infestation in animals challenged with scabies mites. This increase persisted beyond treatment from mite infection and healing of skin. Furthermore, the staphylococci population shifted from the commensal S. hominis on the healthy skin prior to scabies mite challenge to S. chromogenes, which is increasingly recognized as being pathogenic, coinciding with scabies infection in pigs. In contrast, all animals in the scabies-free cohort remained relatively free of Staphylococcus throughout the trial.
Conclusions/Significance
This is the first experimental in vivo evidence supporting previous assumptions that establishment of pathogens follow scabies infection. Our findings provide an explanation for a biologically important aspect of the disease pathogenesis. The methods developed from this pig trial will serve as a guide to analyze human clinical samples. Studies building on this will offer implications for development of novel intervention strategies against the mites and the secondary infections.
Author Summary
Scabies is a neglected, contagious skin disease caused by a parasitic mite Sarcoptes scabiei. It is highly prevalent world-wide, and now recognized as a possible underlying factor for secondary bacterial infections with potential serious downstream complications. There is currently few experimental data demonstrating directly that mite infestation promotes bacterial infections. Due to remarkable similarities in terms of immunology, physiology and skin anatomy between pigs and humans, we developed a sustainable porcine model enabling in vivo studies of scabies mite infestations. Here, we investigated the impact of the scabies mite infection on the normal pig skin microbiota in the inner ear pinnae in young piglets. Samples obtained prior to, during infection and after acaricide treatment were analyzed by sequencing of bacterial 16S rDNA. We report that scabies infestation has an impact on the host's skin microbiota. Staphylococcus abundance increased with the onset of infection and remained beyond treatment and healing. A shift from commensal to pathogenic Staphylococci was observed. This study supports the link between scabies and Staphylococcus infections, as seen in humans. It is the first in vivo demonstration of a mite induced shift in the skin microbiota, providing a basis for a similar study in humans.
doi:10.1371/journal.pntd.0002897
PMCID: PMC4038468  PMID: 24875186
5.  The pattern of skin diseases in the Qassim region of Saudi Arabia: What the primary care physician should know 
Annals of Saudi Medicine  2010;30(6):448-453.
BACKGROUND AND OBJECTIVES:
Epidemiological studies to determine the burden of skin diseases are important for proper health care planning. The purpose of this study was to find the pattern of skin diseases in our patients attending university-affiliated dermatologic clinics in the Qassim region.
METHODS:
We conducted a prospective study of all Saudi patients attending the Qassim University Medical College-affiliated dermatology clinics of the Ministry of Health for a period of 12 months from 1 March 2008 to 28 February 2009.
RESULTS:
The study included 3051 patients comprising 1786 (58.5%) males and 1265 (41.5%) females. Males outnumbered females (P<.05) (male-to-female ratio, 1.4:1). The mean age (standard error of the mean) of the patients was 25.3 (0.27) years. About 71% of the patients were between 5 and 34 years of age. The top five skin diseases were eczema/ dermatitis (19.5%), viral infections (16.6%), pilosebaceous disorders (14.4%), pigmentary lesions (11.2%) and hair disorders (7.6%). The major disorder in males was viral skin infections (20.0%), while eczema/dermatitis (20.7%) constituted the most prevalent skin disease in females. Seasonal variations were recorded in cases of pigmentary lesions, papulosquamous disorders and protozoal infections.
CONCLUSION:
Infectious skin diseases, eczema/dermatitis, pilosebaceous disorders, pigmentary lesions and hair disorders ranked as the top five skin diseases. Appropriate training programs for diagnosing and managing common skin diseases should be initiated for primary health care physicians and other general practitioners so as to decrease referrals to dermatology clinics.
doi:10.4103/0256-4947.72263
PMCID: PMC2994160  PMID: 21060156
6.  A Randomised Controlled Trial of Ion-Exchange Water Softeners for the Treatment of Eczema in Children 
PLoS Medicine  2011;8(2):e1000395.
In a randomized trial evaluating the effect of installation of ion-exchange water softeners in the households of children with eczema, the researchers found no evidence of improvement in eczema severity as compared to usual care in the study population.
Background
Epidemiological studies and anecdotal reports suggest a possible link between household use of hard water and atopic eczema. We sought to test whether installation of an ion-exchange water softener in the home can improve eczema in children.
Methods and Findings
This was an observer-blind randomised trial involving 336 children (aged 6 months to 16 years) with moderate/severe atopic eczema. All lived in hard water areas (≥200 mg/l calcium carbonate). Participants were randomised to either installation of an ion-exchange water softener plus usual eczema care, or usual eczema care alone. The primary outcome was change in eczema severity (Six Area Six Sign Atopic Dermatitis Score, SASSAD) at 12 weeks, measured by research nurses who were blinded to treatment allocation. Analysis was based on the intent-to-treat population. Eczema severity improved for both groups during the trial. The mean change in SASSAD at 12 weeks was −5.0 (20% improvement) for the water softener group and −5.7 (22% improvement) for the usual care group (mean difference 0.66, 95% confidence interval −1.37 to 2.69, p = 0.53). No between-group differences were noted in the use of topical corticosteroids or calcineurin inhibitors.
Conclusions
Water softeners provided no additional benefit to usual care in this study population. Small but statistically significant differences were found in some secondary outcomes as reported by parents, but it is likely that such improvements were the result of response bias, since participants were aware of their treatment allocation. A detailed report for this trial is also available at http://www.hta.ac.uk.
Trial registration
Current Controlled Trials ISRCTN71423189
Please see later in the article for the Editors' Summary
Editors' Summary
Background
Eczema (sometimes referred to as atopic dermatitis) is a chronic, inflammatory skin condition that affects about 20% of school children in developed countries. Eczema is often associated with other conditions, such as asthma, hay-fever and food allergy and can cause intractable itching leading to thickened skin, bleeding, secondary infection, sleep loss, poor concentration, and psychological distress. Current topical treatments for eczema have side effects, for example, topical corticosteroids may cause skin thinning and the long term safety of topical tacrolimus and pimecrolimus has yet to be determined. Therefore, there is a lot of interest in exploring the benefits of non-pharmacological treatments that have no apparent side effects.
Water hardness (≥200 mg/l calcium carbonate) has become a recent focus of attention.
Why Was This Study Done?
In addition to some epidemiological evidence linking increased water hardness with increased eczema prevalence, there have been widespread anecdotal reports of improvement in the skin of children with eczema when the family has moved from a hard to a soft water area. In addition, some patients report how their eczema symptoms have rapidly improved following the installation of a water softener. However, to date there have been no relevant published trials evaluating the potential benefit of water softeners for eczema. Given the lack of evidence, the high public interest in their potential benefit and the low risk of adverse effects, the researcher conducted a study to assess whether the installation of an ion-exchange water softener reduces the severity of eczema in children with moderate to severe eczema.
What Did the Researchers Do and Find?
The researchers did a pilot study that showed that it was not possible to blind participants to their treatment allocation using real and “dummy” water softener units because the softened water produced more soap suds. So the researchers conducted an observer-blind randomised controlled trial in which they used trained research nurses to conduct an objective assessment of every participant's skin. The researchers recruited 336 children who all lived in hard water areas in England. Eligible children were aged 6 months to 16 years who had a diagnosis of eczema (in line with the UK working party's diagnostic criteria) and an eczema severity score of 10 or over. Participants were randomised to either installation of an ion-exchange water softener plus usual eczema care, or usual eczema care alone. Trained research nurses examined each child's skin at baseline and at 6, 12, and 16 weeks to record changes in eczema severity. The researchers also analysed any changes in symptoms over the study period such as, sleep loss and itchiness, the amount of topical corticosteroid/calcineurin inhibitors used, the Dermatitis Family Impact questionnaire and the health related Quality of Life (children's version).
Although both treatment groups improved in disease severity during the course of the trial, the researchers found no difference between the treatment groups in the main outcome—eczema severity. Similar finding were found for night movement (scratching) and the use of topical medications (creams/ointments applied to the skin), both of which were blinded to intervention status. Nevertheless, parents in the trial did report small health benefits, and just over 50% chose to buy the water softener at the end of the trial because of perceived improvements in the eczema and the wider benefits of water softeners. It is unclear how much of this effect can be explained by prior belief in the effectiveness of the water softeners for the treatment of eczema.
What Do These Findings Mean?
The results of this study suggest that water softeners provide no additional clinical benefit to usual care in children with eczema so the use of ion-exchange water softeners for the treatment of moderate to severe eczema in children should not be recommended. However, it is up to each family to decide whether or not the wider benefits of installing a water softener in their home are sufficient to consider buying one.
Additional Information
Please access these Web sites via the online version of this summary at http://dx.doi.org/10.1371/journal.pmed.1000395.
The UK's NHS presents information on eczema for patients and families
MedlinePlus gives information for patients, families, and caregivers on eczema and other similar conditions
The National Eczema Society in the UK provides information and a helpline for eczema patients, families, and caregivers
Medinfo provides information for eczema patients
Wikipedia has more information about water softening (note that Wikipedia is a free online encyclopedia that anyone can edit; available in several languages)
doi:10.1371/journal.pmed.1000395
PMCID: PMC3039684  PMID: 21358807
7.  Skin-Derived TSLP Triggers Progression from Epidermal-Barrier Defects to Asthma 
PLoS Biology  2009;7(5):e1000067.
A skin-derived cytokine with high systemic availability provides a mechanistic explanation for atopic march and highlights a potential therapeutic target for preventing the development of asthma among people with atopic dermatitis.
Asthma is a common allergic lung disease frequently affecting individuals with a prior history of eczema/atopic dermatitis (AD); however, the mechanism underlying the progression from AD to asthma (the so-called “atopic march”) is unclear. Here we show that, like humans with AD, mice with skin-barrier defects develop AD-like skin inflammation and are susceptible to allergic asthma. Furthermore, we show that thymic stromal lymphopoietin (TSLP), overexpressed by skin keratinocytes, is the systemic driver of this bronchial hyper-responsiveness. As an AD-like model, we used mice with keratinocyte-specific deletion of RBP-j that sustained high systemic levels of TSLP. Antigen-induced allergic challenge to the lung airways of RBP-j–deficient animals resulted in a severe asthmatic phenotype not seen in similarly treated wild-type littermates. Elimination of TSLP signaling in these animals blocked the atopic march, demonstrating that high serum TSLP levels were required to sensitize the lung to allergic inflammation. Furthermore, we analyzed outbred K14-TSLPtg mice that maintained high systemic levels of TSLP without developing any skin pathology. Importantly, epidermal-derived TSLP was sufficient to trigger the atopic march, sensitizing the lung airways to inhaled allergens in the absence of epicutaneous sensitization. Based on these findings, we propose that in addition to early treatment of the primary skin-barrier defects, selective inhibition of systemic TSLP may be the key to blocking the development of asthma in AD patients.
Author Summary
Eczema (atopic dermatitis) is a common allergic skin inflammation that has a particularly high prevalence among children. Importantly, a large proportion of people suffering from eczema go on to develop asthma later in life. Although the susceptibility of eczema patients to asthma is well documented, the mechanism that mediates “atopic march”—the progression from eczema to asthma—is unclear. We used genetic engineering to generate mice with chronic skin-barrier defects and a subsequent eczema-like disorder. With these mice, we were able to investigate how skin-specific defects predisposed the lungs to allergic asthma. We identified thymic stromal lymphopoietin (TSLP), a cytokine that is secreted by barrier-defective skin into the systemic circulation, as the agent sensitizing the lung to allergens. We demonstrated that high systemic levels of skin-derived TSLP were both required and sufficient to render lung airways hypersensitive to allergens. Thus, these data suggest that early treatment of skin-barrier defects to prevent TSLP overexpression, and systemic inhibition of TSLP, may be crucial in preventing the progression from eczema to asthma.
doi:10.1371/journal.pbio.1000067
PMCID: PMC2700555  PMID: 19557146
8.  Pattern of Skin Diseases at University of Benin Teaching Hospital, Benin City, Edo State, South-South Nigeria: A 12 Month Prospective Study 
Global Journal of Health Science  2012;4(3):148-157.
Background and Objective:
This study aims to look at the pattern and incidence of skin diseases seen in Dermatology/Venereology clinic at the University of Benin Teaching Hospital, Benin City, Edo State, South-South Zone, Nigeria and compare it with other zones of Nigeria.
Materials and Methods:
This was a prospective study on pattern and incidence of skin diseases in new patients presenting at the Dermatology/Venereology outpatient clinic of the University of Benin Teaching Hospital, Benin City, Edo State, South-South, Nigeria, from September 2006 to August 2007. All patients were seen by the researchers. Diagnosis were made clinically and sometimes with the support of histopathology.
Results:
A total number of 4786 patients were seen during the study period and these comprised 2647 HIV/AIDS patients and 2112 pure Dermatological patients. Out of 4786 patients, 755 (15.8%) were new patients. The new patients comprised 96 (12.7%) children patients (< 15 years) and 659 (83.7%) adult patients (>15years). The ages of the patients ranged from 2 weeks to 80 years and more than two-third were < 40 years. There were 354 males (46.9%) and 401 females (53.1%). This represents female: male ratio of 1.1: 1. Eczematous dermatitis accounted for 20.9% of the skin diseases and was the most common of the skin diseases observed. This is consistent with observation from other zones in Nigeria. Other skin diseases observed in order of frequencies include: Papulosqamous disorder (9.0%), Infectious skin diseases like fungal, viral, bacterial and parasitic infestation, at 7.9%, 7.7%, 2.3% and 2.1% respectively. Pigmentary disorders (5.0%), hair disorders (4.2%) and Benign neoplastic skin disease (6.5%). All the patients that had neurofibromatosis were females (1.9%). HIV-related skin diseases were observed to have increased remarkably (7.9%) with Kaposi’s sarcoma, papular pruritic eruptions and drug eruptions being the commonest mode of presentation.
Conclusion:
The current pattern of skin diseases in Benin City, South-South Nigeria seems to follow a similar pattern observed in other Geo-political zones in Nigeria. The eczematous dermatitis took the lead and the impact of HIV-related skin diseases were vividly noticed to be on the increase. Connective tissue disorder and cutaneous malignancies were low in their occurrences. Our findings showed no major differences in the pattern of skin diseases when compared with other zones of Nigeria. Allergic skin diseases were observed to be on the increase in all the geo-political zones; possibly due to increase in urbanization and its attending socio-economic burden.
doi:10.5539/gjhs.v4n3p148
PMCID: PMC4776906  PMID: 22980241
skin diseases; eczematous dermatitis; infectious skin diseases
9.  Skin diseases in pediatric patients attending a tertiary dermatology hospital in Northern Tanzania: a cross-sectional study 
BMC Dermatology  2015;15:16.
Background
Skin diseases affect 21–87 % of children in developing countries in Africa. However, the spectrum of the skin diseases varies from region to region due to several factors such as genetics, socioeconomic and environmental. The aim of this study was to determine the spectrum of childhood skin diseases in Tanzania.
Methods
We conducted a prospective hospital- based cross-sectional study between September 2012 and August 2013 at a tertiary referral dermatology clinic. Children younger than 14 years presenting with new skin conditions were recruited. Diagnosis was mainly done clinically, but if the diagnosis was not clinically clear, further investigations were undertaken accordingly.
Results
A total of 340 patients were recruited of which 56 (16.5 %) had more than one skin condition. Both genders were equally affected. Infections and infestations accounted for the majority (43.5 %, n = 177) of the skin conditions followed by eczematous dermatitis (28.5 %, n = 116) and pigmentary disorders (7.4 %, n = 30). Among the 152 infectious skin diseases, fungal infections predominated (50.7 %, n = 77) in the infectious group followed by bacterial (29.6 %, n = 45), and viral (19.7 %, n = 30).
Conclusions
Skin infections are still the main cause of dermatological consultations in children although with a reduced prevalence. Inflammatory skin conditions are increasing and can be attributed to improved socioeconomic status and HIV pandemic.
doi:10.1186/s12895-015-0035-9
PMCID: PMC4566193  PMID: 26359248
Pediatric; Skin diseases; Africa
10.  Extracorporeal Photophoresis 
Executive Summary
Objective
To assess the effectiveness, safety and cost-effectiveness of extracorporeal photophoresis (ECP) for the treatment of refractory erythrodermic cutaneous T cell lymphoma (CTCL) and refractory chronic graft versus host disease (cGvHD).
Background
Cutaneous T Cell Lymphoma
Cutaneous T cell lymphoma (CTCL) is a general name for a group of skin affecting disorders caused by malignant white blood cells (T lymphocytes). Cutaneous T cell lymphoma is relatively uncommon and represents slightly more than 2% of all lymphomas in the United States. The most frequently diagnosed form of CTCL is mycosis fungoides (MF) and its leukemic variant Sezary syndrome (SS). The relative frequency and disease-specific 5-year survival of 1,905 primary cutaneous lymphomas classified according to the World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification (Appendix 1). Mycosis fungoides had a frequency of 44% and a disease specific 5-year survival of 88%. Sezary syndrome had a frequency of 3% and a disease specific 5-year survival of 24%.
Cutaneous T cell lymphoma has an annual incidence of approximately 0.4 per 100,000 and it mainly occurs in the 5th to 6th decade of life, with a male/female ratio of 2:1. Mycosis fungoides is an indolent lymphoma with patients often having several years of eczematous or dermatitic skin lesions before the diagnosis is finally established. Mycosis fungoides commonly presents as chronic eczematous patches or plaques and can remain stable for many years. Early in the disease biopsies are often difficult to interpret and the diagnosis may only become apparent by observing the patient over time.
The clinical course of MF is unpredictable. Most patients will live normal lives and experience skin symptoms without serious complications. Approximately 10% of MF patients will experience progressive disease involving lymph nodes, peripheral blood, bone marrow and visceral organs. A particular syndrome in these patients involves erythroderma (intense and usually widespread reddening of the skin from dilation of blood vessels, often preceding or associated with exfoliation), and circulating tumour cells. This is known as SS. It has been estimated that approximately 5-10% of CTCL patients have SS. Patients with SS have a median survival of approximately 30 months.
Chronic Graft Versus Host Disease
Allogeneic hematopoietic cell transplantation (HCT) is a treatment used for a variety of malignant and nonmalignant disease of the bone marrow and immune system. The procedure is often associated with serious immunological complications, particularly graft versus host disease (GvHD). A chronic form of GvHD (cGvHD) afflicts many allogeneic HCT recipients, which results in dysfunction of numerous organ systems or even a profound state of immunodeficiency. Chronic GVHD is the most frequent cause of poor long-term outcome and quality of life after allogeneic HCT. The syndrome typically develops several months after transplantation, when the patient may no longer be under the direct care of the transplant team.
Approximately 50% of patients with cGvHD have limited disease and a good prognosis. Of the patients with extensive disease, approximately 60% will respond to treatment and eventually be able to discontinue immunosuppressive therapy. The remaining patients will develop opportunistic infection, or require prolonged treatment with immunosuppressive agents.
Chronic GvHD occurs in at least 30% to 50% of recipients of transplants from human leukocyte antigen matched siblings and at least 60% to 70% of recipients of transplants from unrelated donors. Risk factors include older age of patient or donor, higher degree of histoincompatibility, unrelated versus related donor, use of hematopoietic cells obtained from the blood rather than the marrow, and previous acute GvHD. Bhushan and Collins estimated that the incidence of severe cGvHD has probably increased in recent years because of the use of more unrelated transplants, donor leukocyte infusions, nonmyeloablative transplants and stem cells obtained from the blood rather than the marrow. The syndrome typically occurs 4 to 7 months after transplantation but may begin as early as 2 months or as late as 2 or more years after transplantation. Chronic GvHD may occur by itself, evolve from acute GvHD, or occur after resolution of acute GvHD.
The onset of the syndrome may be abrupt but is frequently insidious with manifestations evolving gradually for several weeks. The extent of involvement varies significantly from mild involvement limited to a few patches of skin to severe involvement of numerous organ systems and profound immunodeficiency. The most commonly involved tissues are the skin, liver, mouth, and eyes. Patients with limited disease have localized skin involvement, evidence of liver dysfunction, or both, whereas those with more involvement of the skin or involvement of other organs have extensive disease.
Treatment
 
Cutaneous T Cell Lymphoma
The optimal management of MF is undetermined because of its low prevalence, and its highly variable natural history, with frequent spontaneous remissions and exacerbations and often prolonged survival.
Nonaggressive approaches to therapy are usually warranted with treatment aimed at improving symptoms and physical appearance while limiting toxicity. Given that multiple skin sites are usually involved, the initial treatment choices are usually topical or intralesional corticosteroids or phototherapy using psoralen (a compound found in plants which make the skin temporarily sensitive to ultraviolet A) (PUVA). PUVA is not curative and its influence on disease progression remains uncertain. Repeated courses are usually required which may lead to an increased risk of both melanoma and nonmelanoma skin cancer. For thicker plaques, particularly if localized, radiotherapy with superficial electrons is an option.
“Second line” therapy for early stage disease is often topical chemotherapy, radiotherapy or total skin electron beam radiation (TSEB).
Treatment of advanced stage (IIB-IV) MF usually consists of topical or systemic therapy in refractory or rapidly progressive SS.
Bone marrow transplantation and peripheral blood stem cell transplantation have been used to treat many malignant hematologic disorders (e.g., leukemias) that are refractory to conventional treatment. Reports on the use of these procedures for the treatment of CTCL are limited and mostly consist of case reports or small case series.
Chronic Graft Versus Host Disease
Patients who develop cGvHD require reinstitution of immunosuppressive medication (if already discontinued) or an increase in dosage and possibly addition of other agents. The current literature regarding cGvHD therapy is less than optimal and many recommendations about therapy are based on common practices that await definitive testing. Patients with disease that is extensive by definition but is indolent in clinical appearance may respond to prednisone. However, patients with more aggressive disease are treated with higher doses of corticosteroids and/or cyclosporine.
Numerous salvage therapies have been considered in patients with refractory cGvHD, including ECP. Due to uncertainty around salvage therapies, Bhushan and Collins suggested that ideally, patients with refractory cGvHD should be entered into clinical trials.
Two Ontario expert consultants jointly estimated that there may be approximately 30 new erythrodermic treatment resistant CTCL patients and 30 new treatment resistant cGvHD patients per year who are unresponsive to other forms of therapy and may be candidates for ECP.
Extracorporeal photopheresis is a procedure that was initially developed as a treatment for CTCL, particularly SS.
Current Technique
Extracorporeal photopheresis is an immunomodulatory technique based on pheresis of light sensitive cells. Whole blood is removed from patients followed by pheresis. Lymphocytes are separated by centrifugation to create a concentrated layer of white blood cells. The lymphocyte layer is treated with methoxsalen (a drug that sensitizes the lymphocytes to light) and exposed to UVA, following which the lymphocytes are returned to the patient. Red blood cells and plasma are returned to the patient between each cycle.
Photosensitization is achieved by administering methoxsalen to the patient orally 2 hours before the procedure, or by injecting methoxsalen directly ino the leucocyte rich fraction. The latter approach avoids potential side effects such as nausea, and provides a more consistent drug level within the machine.
In general, from the time the intravenous line is inserted until the white blood cells are returned to the patient takes approximately 2.5-3.5 hours.
For CTCL, the treatment schedule is generally 2 consecutive days every 4 weeks for a median of 6 months. For cGvHD, an expert in the field estimated that the treatment schedule would be 3 times a week for the 1st month, then 2 consecutive days every 2 weeks after that (i.e., 4 treatments a month) for a median of 6 to 9 months.
Regulatory Status
The UVAR XTS Photopheresis System is licensed by Health Canada as a Class 3 medical device (license # 7703) for the “palliative treatment of skin manifestations of CTCL.” It is not licensed for the treatment of cGvHD.
UVADEX (sterile solution methoxsalen) is not licensed by Health Canada, but can be used in Canada via the Special Access Program. (Personal communication, Therakos, February 16, 2006)
According to the manufacturer, the UVAR XTS photopheresis system licensed by Health Canada can also be used with oral methoxsalen. (Personal communication, Therakos, February 16, 2006) However, oral methoxsalen is associated with side effects, must be taken by the patient in advance of ECP, and has variable absorption in the gastrointestinal tract.
According to Health Canada, UVADEX is not approved for use in Canada. In addition, a review of the Product Monographs of the methoxsalen products that have been approved in Canada showed that none of them have been approved for oral administration in combination with the UVAR XTS photophoresis system for “the palliative treatment of the skin manifestations of cutaneous T-cell Lymphoma”.
In the United States, the UVAR XTS Photopheresis System is approved by the Food and Drug Administration (FDA) for “use in the ultraviolet-A (UVA) irradiation in the presence of the photoactive drug methoxsalen of extracorporeally circulating leukocyte-enriched blood in the palliative treatment of the skin manifestations of CTCL in persons who have not been responsive to other therapy.”
UVADEX is approved by the FDA for use in conjunction with UVR XTS photopheresis system for “use in the ultraviolet-A (UVA) irradiation in the presence of the photoactive drug methoxsalen of extracorporeally circulating leukocyte-enriched blood in the palliative treatment of the skin manifestations of CTCL in persons who have not been responsive to other therapy.”
The use of the UVAR XTS photopheresis system or UVADEX for cGvHD is an off-label use of a FDA approved device/drug.
Summary of Findings
The quality of the trials was examined.
As stated by the GRADE Working Group, the following definitions were used in grading the quality of the evidence.
Cutaneous T Cell Lymphoma
Overall, there is low-quality evidence that ECP improves response rates and survival in patients with refractory erythrodermic CTCL (Table 1).
Limitations in the literature related to ECP for the treatment of refractory erythrodermic CTCL include the following:
Different treatment regimens.
Variety of forms of CTCL (and not necessarily treatment resistant) - MF, erythrodermic MF, SS.
SS with peripheral blood involvement → role of T cell clonality reporting?
Case series (1 small crossover RCT with several limitations)
Small sample sizes.
Retrospective.
Response criteria not clearly defined/consistent.
Unclear how concomitant therapy contributed to responses.
Variation in definitions of concomitant therapy
Comparison to historical controls.
Some patients were excluded from analysis because of progression of disease, toxicity and other reasons.
Unclear/strange statistics
Quality of life not reported as an outcome of interest.
The reported CR range is ~ 16% to 23% and the overall reported CR/PR range is ~ 33% to 80%.
The wide range in reported responses to ECP appears to be due to the variability of the patients treated and the way in which the data were presented and analyzed.
Many patients, in mostly retrospective case series, were concurrently on other therapies and were not assessed for comparability of diagnosis or disease stage (MF versus SS; erythrodermic versus not erythrodermic). Blood involvement in patients receiving ECP (e.g., T cell clonality) was not consistently reported, especially in earlier studies. The definitions of partial and complete response also are not standardized or consistent between studies.
Quality of life was reported in one study; however, the scale was developed by the authors and is not a standard validated scale.
Adverse events associated with ECP appear to be uncommon and most involve catheter related infections and hypotension caused by volume depletion.
GRADE Quality of Studies – Extracorporeal Photopheresis for Refractory Erythrodermic Cutaneous T-Cell Lymphoma
Chronic Graft-Versus-Host Disease
Overall, there is low-quality evidence that ECP improves response rates and survival in patients with refractory cGvHD (Table 2).
Patients in the studies had stem cell transplants due to a variety of hematological disorders (e.g., leukemias, aplastic anemia, thalassemia major, Hodgkin’s lymphoma, non Hodgkin’s lymphoma).
In 2001, The Blue Cross Blue Shield Technology Evaluation Centre concluded that ECP meets the TEC criteria as treatment of cGvHD that is refractory to established therapy.
The Catalan health technology assessment (also published in 2001) concluded that ECP is a new but experimental therapeutic alternative for the treatment of the erythrodermal phase of CTCL and cGvHD in allogenic HPTC and that this therapy should be evaluated in the framework of a RCT.
Quality of life (Lansky/Karnofsky play performance score) was reported in 1 study.
The patients in the studies were all refractory to steroids and other immunosuppressive agents, and these drugs were frequently continued concomitantly with ECP.
Criteria for assessment of organ improvement in cGvHD are variable, but PR was typically defined as >50% improvement from baseline parameters and CR as complete resolution of organ involvement.
Followup was variable and incomplete among the studies.
GRADE Quality of Studies – ECP for Refractory cGvHD
Conclusion
As per the GRADE Working Group, overall recommendations consider 4 main factors.
The tradeoffs, taking into account the estimated size of the effect for the main outcome, the confidence limits around those estimates and the relative value placed on the outcome.
The quality of the evidence (Tables 1 and 2).
Translation of the evidence into practice in a specific setting, taking into consideration important factors that could be expected to modify the size of the expected effects such as proximity to a hospital or availability of necessary expertise.
Uncertainty about the baseline risk for the population of interest.
The GRADE Working Group also recommends that incremental costs of healthcare alternatives should be considered explicitly alongside the expected health benefits and harms. Recommendations rely on judgments about the value of the incremental health benefits in relation to the incremental costs. The last column in Table 3 is the overall trade-off between benefits and harms and incorporates any risk/uncertainty.
For refractory erythrodermic CTCL, the overall GRADE and strength of the recommendation is “weak” – the quality of the evidence is “low” (uncertainties due to methodological limitations in the study design in terms of study quality and directness), and the corresponding risk/uncertainty is increased due to an annual budget impact of approximately $1.5M Cdn (based on 30 patients) while the cost-effectiveness of ECP is unknown and difficult to estimate considering that there are no high quality studies of effectiveness. The device is licensed by Health Canada, but the sterile solution of methoxsalen is not licensed.
With an annual budget impact of $1.5 M Cdn (based on 30 patients), and the current expenditure is $1.3M Cdn (for out of country for 7 patients), the potential cost savings based on 30 patients with refractory erythrodermic CTCL is about $3.8 M Cdn (annual).
For refractory cGvHD, the overall GRADE and strength of the recommendation is “weak” – the quality of the evidence is “low” (uncertainties due to methodological limitations in the study design in terms of study quality and directness), and the corresponding risk/uncertainty is increased due to a budget impact of approximately $1.5M Cdn while the cost-effectiveness of ECP is unknown and difficult to estimate considering that there are no high quality studies of effectiveness. Both the device and sterile solution are not licensed by Health Canada for the treatment of cGvHD.
If all the ECP procedures for patients with refractory erythrodermic CTCL and refractory cGvHD were performed in Ontario, the annual budget impact would be approximately $3M Cdn.
Overall GRADE and Strength of Recommendation (Including Uncertainty)
PMCID: PMC3379535  PMID: 23074497
11.  The Prevalence of Scabies and Impetigo in the Solomon Islands: A Population-Based Survey 
PLoS Neglected Tropical Diseases  2016;10(6):e0004803.
Background
Scabies and impetigo are common, important and treatable skin conditions. Reports from several Pacific island countries show extremely high prevalence of these two conditions, but for many countries, including the Solomon Islands, there is a paucity of epidemiological data.
Methodology
Ten rural villages in the Western Province of the Solomon Islands were included in the study, chosen so that data collection could be integrated with an existing project investigating clinical and serological markers of yaws. All residents were eligible to participate, and 1908 people were enrolled. Participants were interviewed and examined by a paediatric registrar, who recorded relevant demographic information, and made a clinical diagnosis of scabies and/or impetigo, severity and distribution.
Principal Findings
The total unweighted prevalence of scabies was 19.2% (95% confidence interval [CI] 17.5–21.0), and age and gender weighted prevalence 19.2% (95%CI 16.7–21.9). The adult prevalence of scabies was 10.4% (95%CI 8.2–13.2), and the highest prevalence was found in infants < 1 year of age (34.1%, adjusted odds ratio [AOR] compared with adults: 3.6, 95%CI 2.2–6.0) and children aged 1–4 years (25.7%, AOR 2.6, 95%CI 1.7–3.9). Scabies affected two or more body regions in 80.9% of participants, and 4.4% of scabies cases were classified as severe. The total unweighted prevalence of active impetigo was 32.7% (95%CI 30.6–34.8), and age and gender weighted prevalence 26.7% (95%CI 24.2–29.5). The highest prevalence was found in children aged 1–4 years (42.6%, AOR compared with adults: 4.1, 95%CI 2.9–5.8). Scabies infestation was associated with active impetigo infection (AOR 2.0, 95%CI 1.6–2.6); with 41.1% of active impetigo cases also having scabies.
Conclusions and Significance
Scabies and impetigo are very common in the rural Western Province of the Solomon Islands. Scabies infestation is strongly associated with impetigo. Community control strategies for scabies may reduce the burden of both conditions and their downstream complications.
Author Summary
Scabies, a parasitic infection, and impetigo, a superficial bacterial infection, are treatable skin conditions found most commonly in resource-limited settings. Scabies is strongly associated with impetigo. Complications of impetigo include sepsis and invasive infections, and post-infective complications such as acute post streptococcal glomerulonephritis and acute rheumatic fever. Good data on scabies and impetigo prevalence are lacking for most countries, but existing evidence suggests the Pacific region has among the highest prevalence of these conditions in the world. Our study aimed to establish the prevalence of scabies and impetigo in the Western Province of the Solomon Islands, a South Pacific nation made up of over 900 islands and over 500,000 inhabitants. We assessed over 1900 people of all ages, and found a very high burden of skin infections, with scabies affecting one in five people, and active impetigo in one in three. Infants and children were affected more than adults. Scabies infestation was strongly associated with impetigo, supporting the hypothesis that community control strategies for scabies may be successful in reducing the burden of impetigo and its sequelae.
doi:10.1371/journal.pntd.0004803
PMCID: PMC4922659  PMID: 27348119
12.  High Prevalence of Skin Disorders among HTLV-1 Infected Individuals Independent of Clinical Status 
Background
Human T-cell lymphotropic virus type 1 (HTLV-1) infection can increase the risk of developing skin disorders. This study evaluated the correlation between HTLV-1 proviral load and CD4+ and CD8+ T cells count among HTLV-1 infected individuals, with or without skin disorders (SD) associated with HTLV-1 infection [SD-HTLV-1: xerosis/ichthyosis, seborrheic dermatitis or infective dermatitis associated to HTLV-1 (IDH)].
Methods
A total of 193 HTLV-1-infected subjects underwent an interview, dermatological examination, initial HTLV-1 proviral load assay, CD4+ and CD8+ T cells count, and lymphproliferation assay (LPA).
Results
A total of 147 patients had an abnormal skin condition; 116 (79%) of them also had SD-HTLV-1 and 21% had other dermatological diagnoses. The most prevalent SD-HTLV-1 was xerosis/acquired ichthyosis (48%), followed by seborrheic dermatitis (28%). Patients with SD-HTLV-1 were older (51 vs. 47 years), had a higher prevalence of myelopathy/tropical spastic paraparesis (HAM/TSP) (75%), and had an increased first HTLV-1 proviral load and basal LPA compared with patients without SD-HTLV-1. When excluding HAM/TSP patients, the first HTLV-1 proviral load of SD-HTLV-1 individuals remains higher than no SD-HTLV-1 patients.
Conclusions
There was a high prevalence of skin disorders (76%) among HTLV-1-infected individuals, regardless of clinical status, and 60% of these diseases are considered skin disease associated with HTLV-1 infection.
Author Summary
HTLV-1 infection may increase the risk of developing skin disorders. A total of 193 HTLV-1 infected subjects were studied, including asymptomatic carriers and HAM/TSP patients. Of the subjects, 76% had an abnormal skin condition, with a high prevalence both among HTLV-1 asymptomatic carriers and HAM/TSP patients. The most prevalent SD-HTLV-1 was xerosis/acquired ichthyosis (48%), followed by seborrheic dermatitis (28%). Patients with SD-HTLV-1 were older (51 vs. 47 years), had a higher prevalence of myelopathy/tropical spastic paraparesis (HAM/TSP) (75%) and an increased first HTLV-1 proviral load compared with patients without SD-HTLV-1. When excluding HAM/TSP patients, the first HTLV-1 proviral load of SD-HTLV-1 individuals remains higher than no SD-HTLV-1 patients. Thus, skin diseases are highly prevalent among HTLV-1-infected individuals.
doi:10.1371/journal.pntd.0002546
PMCID: PMC3820737  PMID: 24244779
13.  Ultraviolet Phototherapy Management of Moderate-to-Severe Plaque Psoriasis 
Executive Summary
Objective
The purpose of this evidence based analysis was to determine the effectiveness and safety of ultraviolet phototherapy for moderate-to-severe plaque psoriasis.
Research Questions
The specific research questions for the evidence review were as follows:
What is the safety of ultraviolet phototherapy for moderate-to-severe plaque psoriasis?
What is the effectiveness of ultraviolet phototherapy for moderate-to-severe plaque psoriasis?
Clinical Need: Target Population and Condition
Psoriasis is a common chronic, systemic inflammatory disease affecting the skin, nails and occasionally the joints and has a lifelong waning and waxing course. It has a worldwide occurrence with a prevalence of at least 2% of the general population, making it one of the most common systemic inflammatory diseases. The immune-mediated disease has several clinical presentations with the most common (85% - 90%) being plaque psoriasis.
Characteristic features of psoriasis include scaling, redness, and elevation of the skin. Patients with psoriasis may also present with a range of disabling symptoms such as pruritus (itching), pain, bleeding, or burning associated with plaque lesions and up to 30% are classified as having moderate-to-severe disease. Further, some psoriasis patients can be complex medical cases in which diabetes, inflammatory bowel disease, and hypertension are more likely to be present than in control populations and 10% also suffer from arthritis (psoriatic arthritis). The etiology of psoriasis is unknown but is thought to result from complex interactions between the environment and predisposing genes.
Management of psoriasis is related to the extent of the skin involvement, although its presence on the hands, feet, face or genitalia can present challenges. Moderate-to-severe psoriasis is managed by phototherapy and a range of systemic agents including traditional immunosuppressants such as methotrexate and cyclospsorin. Treatment with modern immunosuppressant agents known as biologicals, which more specifically target the immune defects of the disease, is usually reserved for patients with contraindications and those failing or unresponsive to treatments with traditional immunosuppressants or phototherapy.
Treatment plans are based on a long-term approach to managing the disease, patient’s expectations, individual responses and risk of complications. The treatment goals are several fold but primarily to:
1) improve physical signs and secondary psychological effects,
2) reduce inflammation and control skin shedding,
3) control physical signs as long as possible, and to
4) avoid factors that can aggravate the condition.
Approaches are generally individualized because of the variable presentation, quality of life implications, co-existent medical conditions, and triggering factors (e.g. stress, infections and medications). Individual responses and commitments to therapy also present possible limitations.
Phototherapy
Ultraviolet phototherapy units have been licensed since February 1993 as a class 2 device in Canada. Units are available as hand held devices, hand and foot devices, full-body panel, and booth styles for institutional and home use. Units are also available with a range of ultraviolet A, broad and narrow band ultraviolet B (BB-UVB and NB-UVB) lamps. After establishing appropriate ultraviolet doses, three-times weekly treatment schedules for 20 to 25 treatments are generally needed to control symptoms.
Evidence-Based Analysis Methods
The literature search strategy employed keywords and subject headings to capture the concepts of 1) phototherapy and 2) psoriasis. The search involved runs in the following databases: Ovid MEDLINE (1996 to March Week 3 2009), OVID MEDLINE In-Process and Other Non-Indexed Citations, EMBASE (1980 to 2009 Week 13), the Wiley Cochrane Library, and the Centre for Reviews and Dissemination/International Agency for Health Technology Assessment. Parallel search strategies were developed for the remaining databases. Search results were limited to human and English-language published between January 1999 and March 31, 2009. Search alerts were generated and reviewed for relevant literature up until May 31, 2009.
English language reports and human studies
Ultraviolet phototherapy interventions for plaque-type psoriasis
Reports involving efficacy and/or safety outcome studies
Original reports with defined study methodology
Standardized measurements on outcome events such as technical success, safety, effectiveness, durability, quality of life or patient satisfaction
Non-systematic reviews, letters, comments and editorials
Randomized trials involving side-to-side or half body comparisons
Randomized trials not involving ultraviolet phototherapy intervention for plaque-type psoriasis
Trials involving dosing studies, pilot feasibility studies or lacking control groups
Summary of Findings
A 2000 health technology evidence report on the overall management of psoriasis by The National Institute Health Research (NIHR) Health Technology Assessment Program of the UK was identified in the MAS evidence-based review. The report included 109 RCT studies published between 1966 and June 1999 involving four major treatment approaches – 51 on phototherapy, 32 on oral retinoids, 18 on cyclosporin and five on fumarates.. The absence of RCTs on methotrexate was noted as original studies with this agent had been performed prior to 1966.
Of the 51 RCT studies involving phototherapy, 22 involved UVA, 21 involved UVB, five involved both UVA and UVB and three involved natural light as a source of UV. The RCT studies included comparisons of treatment schedules, ultraviolet source, addition of adjuvant therapies, and comparisons between phototherapy and topical treatment schedules. Because of heterogeneity, no synthesis or meta-analysis could be performed. Overall, the reviewers concluded that the efficacy of only five therapies could be supported from the RCT-based evidence review: photochemotherapy or phototherapy, cyclosporin, systemic retinoids, combination topical vitamin D3 analogues (calcipotriol) and corticosteroids in combination with phototherapy and fumarates. Although there was no RCT evidence supporting methotrexate, it’s efficacy for psoriasis is well known and it continues to be a treatment mainstay.
The conclusion of the NIHR evidence review was that both photochemotherapy and phototherapy were effective treatments for clearing psoriasis, although their comparative effectiveness was unknown. Despite the conclusions on efficacy, a number of issues were identified in the evidence review and several areas for future research were discussed to address these limitations. Trials focusing on comparative effectiveness, either between ultraviolet sources or between classes of treatment such as methotrexate versus phototherapy, were recommended to refine treatment algorithms. The need for better assessment of cost-effectiveness of therapies to consider systemic drug costs and costs of surveillance, as well as drug efficacy, were also noted. Overall, the authors concluded that phototherapy and photochemotherapy had important roles in psoriasis management and were standard therapeutic options for psoriasis offered in dermatology practices.
The MAS evidence-based review focusing on the RCT trial evidence for ultraviolet phototherapy management of moderate-to-severe plaque psoriasis was performed as an update to the NIHR 2000 systemic review on treatments for severe psoriasis. In this review, an additional 26 RCT reports examining phototherapy or photochemotherapy for psoriasis were identified. Among the studies were two RCTs comparing ultraviolet wavelength sources, five RCTs comparing different forms of phototherapy, four RCTs combining phototherapy with prior spa saline bathing, nine RCTs combining phototherapy with topical agents, two RCTs combining phototherapy with the systemic immunosuppressive agents methotrexate or alefacept, one RCT comparing phototherapy with an additional light source (the excimer laser), and one comparing a combination therapy with phototherapy and psychological intervention involving simultaneous audiotape sessions on mindfulness and stress reduction. Two trials also examined the effect of treatment setting on effectiveness of phototherapy, one on inpatient versus outpatient therapy and one on outpatient clinic versus home-based phototherapy.
Conclusions
The conclusions of the MAS evidence-based review are outlined in Table ES1. In summary, phototherapy provides good control of clinical symptoms in the short term for patients with moderate-to-severe plaque-type psoriasis that have failed or are unresponsive to management with topical agents. However, many of the evidence gaps identified in the NIHR 2000 evidence review on psoriasis management persisted. In particular, the lack of evidence on the comparative effectiveness and/or cost-effectiveness between the major treatment options for moderate-to-severe psoriasis remained. The evidence on effectiveness and safety of longer term strategies for disease management has also not been addressed. Evidence for the safety, effectiveness, or cost-effectiveness of phototherapy delivered in various settings is emerging but is limited. In addition, because all available treatments for psoriasis – a disease with a high prevalence, chronicity, and cost – are palliative rather than curative, strategies for disease control and improvements in self-efficacy employed in other chronic disease management strategies should be investigated.
RCT Evidence for Ultraviolet Phototherapy Treatment of Moderate-To-Severe Plaque Psoriasis
Phototherapy is an effective treatment for moderate-to-severe plaque psoriasis
Narrow band PT is more effective than broad band PT for moderate-to-severe plaque psoriasis
Oral-PUVA has a greater clinical response, requires less treatments and has a greater cumulative UV irradiation dose than UVB to achieve treatment effects for moderate-to-severe plaque psoriasis
Spa salt water baths prior to phototherapy did increase short term clinical response of moderate-to-severe plaque psoriasis but did not decrease cumulative UV irradiation dose
Addition of topical agents (vitamin D3 calcipotriol) to NB-UVB did not increase mean clinical response or decrease treatments or cumulative UV irradiation dose
Methotrexate prior to NB-UVB in high need psoriasis patients did significantly increase clinical response, decrease number of treatment sessions and decrease cumulative UV irradiation dose
Phototherapy following alefacept did increase early clinical response in moderate-to-severe plaque psoriasis
Effectiveness and safety of home NB-UVB phototherapy was not inferior to NB-UVB phototherapy provided in a clinic to patients with psoriasis referred for phototherapy. Treatment burden was lower and patient satisfaction was higher with home therapy and patients in both groups preferred future phototherapy treatments at home
Ontario Health System Considerations
A 2006 survey of ultraviolet phototherapy services in Canada identified 26 phototherapy clinics in Ontario for a population of over 12 million. At that time, there were 177 dermatologists and 50 geographic regions in which 28% (14/50) provided phototherapy services. The majority of the phototherapy services were reported to be located in densely populated areas; relatively few patients living in rural communities had access to these services. The inconvenience of multiple weekly visits for optimal phototherapy treatment effects poses additional burdens to those with travel difficulties related to health, job, or family-related responsibilities.
Physician OHIP billing for phototherapy services totaled 117,216 billings in 2007, representing approximately 1,800 patients in the province treated in private clinics. The number of patients treated in hospitals is difficult to estimate as physician costs are not billed directly to OHIP in this setting. Instead, phototherapy units and services provided in hospitals are funded by hospitals’ global budgets. Some hospitals in the province, however, have divested their phototherapy services, so the number of phototherapy clinics and their total capacity is currently unknown.
Technological advances have enabled changes in phototherapy treatment regimens from lengthy hospital inpatient stays to outpatient clinic visits and, more recently, to an at-home basis. When combined with a telemedicine follow-up, home phototherapy may provide an alternative strategy for improved access to service and follow-up care, particularly for those with geographic or mobility barriers. Safety and effectiveness have, however, so far been evaluated for only one phototherapy home-based delivery model. Alternate care models and settings could potentially increase service options and access, but the broader consequences of the varying cost structures and incentives that either increase or decrease phototherapy services are unknown.
Economic Analyses
The focus of the current economic analysis was to characterize the costs associated with the provision of NB-UVB phototherapy for plaque-type, moderate-to-severe psoriasis in different clinical settings, including home therapy. A literature review was conducted and no cost-effectiveness (cost-utility) economic analyses were published in this area.
Hospital, Clinic, and Home Costs of Phototherapy
Costs for NB-UVB phototherapy were based on consultations with equipment manufacturers and dermatologists. Device costs applicable to the provision of NB-UVB phototherapy in hospitals, private clinics and at a patient’s home were estimated. These costs included capital costs of purchasing NB-UVB devices (amortized over 15-20 years), maintenance costs of replacing equipment bulbs, physician costs of phototherapy treatment in private clinics ($7.85 per phototherapy treatment), and medication and laboratory costs associated with treatment of moderate-to-severe psoriasis.
NB-UVB phototherapy services provided in a hospital setting were paid for by hospitals directly. Phototherapy services in private clinic and home settings were paid for by the clinic and patient, respectively, except for physician services covered by OHIP. Indirect funding was provided to hospitals as part of global budgeting and resource allocation. Home therapy services for NB-UVB phototherapy were not covered by the MOHLTC. Coverage for home-based phototherapy however, was in some cases provided by third party insurers.
Device costs for NB-UVB phototherapy were estimated for two types of phototherapy units: a “booth unit” consisting of 48 bulbs used in hospitals and clinics, and a “panel unit” consisting of 10 bulbs for home use. The device costs of the booth and panel units were estimated at approximately $18,600 and $2,900, respectively; simple amortization over 15 and 20 years implied yearly costs of approximately $2,500 and $150, respectively. Replacement cost for individual bulbs was about $120 resulting in total annual cost of maintenance of about $8,640 and $120 for booth and panel units, respectively.
Estimated Total Costs for Ontario
Average annual cost per patient for NB-UVB phototherapy provided in the hospital, private clinic or at home was estimated to be $292, $810 and $365 respectively. For comparison purposes, treatment of moderate-to-severe psoriasis with methotrexate and cyclosporin amounted to $712 and $3,407 annually per patient respectively; yearly costs for biological drugs were estimated to be $18,700 for alefacept and $20,300 for etanercept-based treatments.
Total annual costs of NB-UVB phototherapy were estimated by applying average costs to an estimated proportion of the population (age 18 or older) eligible for phototherapy treatment. The prevalence of psoriasis was estimated to be approximately 2% of the population, of which about 85% was of plaque-type psoriasis and approximately 20% to 30% was considered moderate-to-severe in disease severity. An estimate of 25% for moderate-to-severe psoriasis cases was used in the current economic analysis resulting in a range of 29,400 to 44,200 cases. Approximately 21% of these patients were estimated to be using NB-UVB phototherapy for treatment resulting in a number of cases in the range between 6,200 and 9,300 cases. The average (7,700) number of cases was used to calculate associated costs for Ontario by treatment setting.
Total annual costs were as follows: $2.3 million in a hospital setting, $6.3 million in a private clinic setting, and $2.8 million for home phototherapy. Costs for phototherapy services provided in private clinics were greater ($810 per patient annually; total of $6.3 million annually) and differed from the same services provided in the hospital setting only in terms of additional physician costs associated with phototherapy OHIP fees.
Keywords
Psoriasis, ultraviolet radiation, phototherapy, photochemotherapy, NB-UVB, BB-UVB PUVA
PMCID: PMC3377497  PMID: 23074532
14.  Epidemiology of Skin Disease in an Automobile Factory* 
A survey was made of a random sample of workers from the machine shops, assembly lines, and stock and store departments of an automobile factory. Among the 1,223 men seen, representing 97% of the sample, the prevalence of non-infective skin diseases was 14·5%. Skin diseases were classified into four groups: `dermatitis' and `folliculitis' of occupational origin, endogenous `eczemas', and miscellaneous skin diseases. Slightly more than half of all the skin diseases seen were considered to be occupational in origin.
In this population the prevalence of skin disease was more than four times that based on patients attending the factory medical department.
An unsuspected cause of allergic dermatitis was found on the assembly lines, where the incidence of dermatitis was significantly higher than among the non-production workers. The prevalence of folliculitis was significantly higher among production than non-production workers. There was no significant difference in the prevalence of `eczema' or the miscellaneous skin diseases in the various occupational groups.
Among European workers fair men were more prone to skin disease than darker men. In another factory, a West Indian and Asiatic group of workers had a significantly lower prevalence of skin diseases than a group of Europeans doing similar work.
Folliculitis was more prevalent among the younger workers and those recently employed in the factory; there was no obvious association between age and length of service and the occurrence of other types of skin disease.
PMCID: PMC1038403  PMID: 14249898
15.  Recurrent wheezing is associated with intestinal protozoan infections in Warao Amerindian children in Venezuela: a cross-sectional survey 
BMC Infectious Diseases  2014;14:293.
Background
While in developed countries the prevalence of allergic diseases is rising, inflammatory diseases are relatively uncommon in rural developing areas. High prevalence rates of helminth and protozoan infections are commonly found in children living in rural settings and several studies suggest an inverse association between helminth infections and allergies. No studies investigating the relationship between parasitic infections and atopic diseases in rural children of developing countries under the age of 2 years have been published so far. We performed a cross-sectional survey to investigate the association of helminth and protozoan infections and malnutrition with recurrent wheezing and atopic eczema in Warao Amerindian children in Venezuela.
Methods
From August to November 2012, 229 children aged 0 to 2 years residing in the Orinoco Delta in Venezuela were enrolled. Data were collected through standardized questionnaires and physical examination, including inspection of the skin and anthropometric measurements. A stool sample was requested from all participants and detection of different parasites was performed using microscopy and real time polymerase chain reaction (PCR).
Results
We observed high prevalence rates of atopic eczema and recurrent wheezing, respectively 19% and 23%. The prevalence of helminth infections was 26% and the prevalence of protozoan infections was 59%. Atopic eczema and recurrent wheezing were more frequently observed in stunted compared with non-stunted children in multivariable analysis (OR 4.3, 95% CI 1.3 – 13.6, p = 0.015 and OR 4.5, 95% CI 0.97 – 21.2, p = 0.055). Furthermore, recurrent wheezing was significantly more often observed in children with protozoan infections than in children without protozoan infections (OR 6.7, 95% CI 1.5 – 30.5).
Conclusions
High prevalence rates of atopic eczema and recurrent wheezing in Warao Amerindian children under 2 years of age were related to stunting and intestinal protozoan infections respectively. Helminth infections were not significantly associated with either atopic eczema or recurrent wheezing.
doi:10.1186/1471-2334-14-293
PMCID: PMC4045948  PMID: 24885094
Atopic eczema; Helminth; Indigenous children; Malnutrition; Protozoa; Recurrent wheezing
16.  Comparative Proteomic Profiling of Atopic Dermatitis Patients Based on History of Eczema Herpeticum Infection and Staphylococcus aureus Colonization 
Background
Atopic dermatitis is the most common inflammatory skin disorder in the general population worldwide and the majority of patients are colonized with Staphylococcus aureus. Eczema herpeticum is a disseminated herpes simplex virus infection that occurs in a small subset of patients.
Objectives
The goal was to conduct proteomic profiling of atopic dermatitis patients based on Staphylococcus aureus colonization status and history of eczema herpeticum. We hoped to identify new biomarkers for improved diagnosis and prediction of eczema herpeticum and Staphylococcus aureus susceptibility, and to generate new hypotheses regarding disease pathogenesis.
Methods
Skin taping was performed on nonlesional skin of non-atopic controls and on lesional and nonlesional skin of atopic dermatitis patients. Subjects were classified according to history of eczema herpeticum and Staphylococcus aureus colonization. Proteins were analyzed using mass spectrometry; diagnostic groups were compared for statistically significant differences in protein expression.
Results
Proteins related to the skin barrier (filaggrin-2, corneodesmosin, desmoglein-1, desmocollin-1, and transglutaminase-3) and generation of natural moisturizing factor (arginase-1, caspase-14, gamma-glutamyl cyclotransferase) were expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patients with and without history of eczema herpeticum; epidermal fatty acid binding protein was expressed at significantly higher levels in patients with methicillin resistant Staphylococcus aureus.
Conclusion
This non-invasive, semi-quantitative profiling method has revealed novel proteins likely involved in the pathogenesis of atopic dermatitis. The lower expression of skin barrier proteins and enzymes involved in the generation of the natural moisturizing factor could further exacerbate barrier defects and perpetuate water loss from the skin. The greater expression of epidermal fatty acid binding protein, especially in patients colonized with methicillin-resistant Staphylococcus aureus, may perpetuate the inflammatory response via eicosanoid signaling.
doi:10.1016/j.jaci.2010.10.033
PMCID: PMC3059191  PMID: 21211653
Atopic dermatitis; mass spectrometry; proteomics; natural moisturizing factor; eczema herpeticum; tape stripping; skin barrier; filaggrin-2; epidermal fatty acid binding protein; methicillin-resistant Staphylococcus aureus
17.  7th Drug hypersensitivity meeting: part two 
Elera, Javier Dionicio | Boteanu, Cosmin | Blanco, Maria Aranzazu Jimenez | Gonzalez-Mendiola, Rosario | García, Irene Carrasco | Alvarez, Antonio | Martinez, Jose Julio Laguna | Garrido, Jaume Martí | Barona, Carla Torán | Chorda, Carolina Perales | Salgueiro, Ramón López | Palacios, Miguel Díaz | De Rojas, Dolores Hernández Fernández | Acar, Emre Ali | Aktas, Ayse | Ermertcan, Aylin Türel | Temiz, Peyker | Lin, Chien-Yio | Hui, Chung-Yee Rosaline | Chang, Ya-Ching | Yang, Chih-Hsun | Chung, Wen-Hung | Carolino, Fabrícia | Silva, Diana | De Castro, Eunice Dias | Cernadas, Josefina R. | Ensina, Luis Felipe | Aranda, Carolina | Nunes, Ines Camelo | Lacerda, Alex | Martins, Ana Maria | Goudouris, Ekaterini | Ribeiro, Marcia | Da Silva Franco, José Francisco | Queiroz, Leandra | Solé, Dirceu | Dalgiç, Ceyda Tunakan | Sin, Aytül Zerrin | Günsen, Fatma Düsünür | Bulut, Gökten | Ardeniz, Fatma Ömür | Gülbahar, Okan | Gökmen, Emine Nihal Mete | Kokuludag, Ali | De Francisco, Ana M. Montoro | De Vicente Jiménez, Talía Mª | Mendoza Parra, Adriana M. | Burgos Pimentel, Angella M. | Luque, Amelia García | Amaral, Luis | Leão, Leonor Carneiro | Pinto, Nicole | Belo, Joana | Marques, João | Carreiro-Martins, Pedro | Leiria-Pinto, Paula | Chaabane, Amel | Romdhane, Haifa Ben | Fredj, Nadia Ben | Chadly, Zohra | Boughattas, Naceur A. | Aouam, Karim | Uyttebroek, Astrid P. | Bridts, Chris H. | Romano, Antonino | Ebo, Didier G. | Sabato, Vito | Lopes, Anabela | Cosme, Joana | Aguiar, Rita | Lourenço, Tatiana | Paes, Maria-João | Spínola-Santos, Amélia | Pereira-Barbosa, Manuel | Cruz, Cíntia Rito | Dos Reis, Rute Pereira | Tomaz, Elza | Pires, Ana Paula | Inácio, Filipe | Benito-Garcia, Filipe | Mota, Inês | Correia, Magna | Gaspar, Ângela | Chambel, Marta | Piedade, Susana | Morais-Almeida, Mário | Nakonechna, Alla | Antipkin, Yurij | Umanets, Tetiana | Pineda, Fernando | Arribas, Francisca | Lapshyn, Volodymyr | Miranda, Pablo Andrés | De La Cruz Hoyos, Bautista | Blanco, Aranzazu Jimenez | Del Pozo, Marta | Vultaggio, Alessandra | Nencini, Francesca | Pratesi, Sara | Matucci, Andrea | Maggi, Enrico | Cegec, Ivana | Nahal, Danica Juricic | Turk, Viktorija Erdeljic | Aumiler, Matea Radacic | Ausperger, Ksenija Makar | Kraljickovic, Iva | Simic, Iveta | Yamaguchi, Yukie | Watanabe, Tomoya | Satoh, Megumi | Tanegashima, Tomohiko | Oda, Kayoko | Wada, Hidefumi | Aihara, Michiko | Lee, Jaechun Jason | Choi, Jay Chol | Lee, Hwa Young | Fernandes, Rosa-Anita Rodrigues | Faria, Emília | Pita, Joana | Sousa, Nuno | Ribeiro, Carmelita | Carrapatoso, Isabel | Bom, Ana Todo | Rodolfo, Ana | Dias-Castro, Eunice | Voronova, Marina | Valle, Diana Kury | Coronel, Verónica Pacheco | Chordá, Carolina Perales | Madamba, Roselle Catherine Yu | Ferrer, Marta | Goikoetxea, Maria Jose | D’Amelio, Carmen | Bernad, Amalia | Vega, Olga | Gastaminza, Gabriel | Bibián, Beatriz Pola | Salazar, Marina Lluncor | Vilà-Nadal, Gemma | Roman, Ana María Fiandor | Ortega, Javier Dominguez | Muñoz, Miguel Gonzalez | Gancedo, Santiago Quirce | Moreno, Maria Rosario Cabañas | Hofmeier, Kathrin Scherer | Barzylovych, Vladyslava | Pola, Beatriz | Lluncor, Marina | Fiandor, Ana | Bellón, Teresa | Domínguez, Javier | Quirce, Santiago | Yang, Min-Suk | Kim, Sun-Sin | Kim, Sae-Hoon | Kang, Hye-Ryun | Park, Heung-Woo | Cho, Sang-Heon | Min, Kyung-Up | Chang, Yoon-Seok | Delahaye, Clémence | Flabbee, Jenny | Waton, Julie | Bauvin, Olivia | Barbaud, Annick | Fadhel, Najah Ben | Gulin, Sandra Jerkovic | Chiriac, Anca | Cardoso, Bárbara Kong | Viseu, Regina | Moreira, Ana | Cadinha, Susana | Neves, Ana Castro | Barreira, Patrícia | Malheiro, Daniela | Da Silva, J. P. Moreira | Jurakic-Toncic, Ružica | Ljubojevic, Suzana | Turcic, Petra | Gilissen, Liesbeth | Huygens, Sara | Goossens, An | Andreu, Inmaculada | Romero, Alicia Martinez | Cabezas, Pau Gomez | Parejo, Pedro Ayuso | Del Carmen Plaza-Serón, Maria | Doña, Inmaculada | Blanca-López, Natalia | Flores, Carlos |