PMCC PMCC

Search tips
Search criteria

Advanced
Results 1-25 (386562)

Clipboard (0)
None

Related Articles

1.  Pharmacognostic and antifungal investigations of Elaeocarpus ganitrus (Rudrakasha) 
Rudrakasha is the dried bead obtained from the ripe fruit of Elaeocarpus ganitrus Roxb. (Family: Elaeocarpaceae). Microscopic studies revealed the presence of a hard endocarp with lignified isodiametric sclereids, seeds with membranous seed coat, which enclosed a dense cellular endosperm comprising of calcium oxalate druses. Physicochemical parameters showed that total ash was 1.36 times and 1.56 times more than the acid insoluble ash and water-soluble ash, respectively. Further, ethanol had a maximum extractable value of 2.4% and moisture content was found to be 9.7%. Different extracts, petroleum ether, chloroform, ethanol and water were prepared. Chemically the extracts showed the presence of phytosterols, fats, alkaloids, flavonoids, carbohydrates, proteins and tannins. The extracts were evaluated for antifungal activity on different fungal strains. Chlorofom and ethanol extracts have high antifungal activity against Candida albicans. Whereas, chloroform, ethanol and water extracts showed moderate inhibition against Aspergillus niger.
doi:10.4103/0250-474X.65021
PMCID: PMC2929793  PMID: 20838538
Rudrakasha; Elaeocarpus ganitrus; antifungal activity; Candida albicans; Aspergillus niger
2.  Pharmacognostical and physicochemical evaluation of Agasti leaf 
Sesbania grandiflora (L.) Pers., commonly known as Agasti, is widely used in Ayurveda for the treatment of diseases and for processing of various formulations in Rasashastra. It is used for its astringent, antihistaminic, anxiolytic, anticonvulsive and febrifugal activities. Moreover, because of its edible nature, the leaves and pods are used as flavoring items in the cuisine of South India. A detailed investigation of fresh and powder of leaves of Agasti was carried out. The diagnostic characters of this plant include stomatal characters, presence of resins, oil globules, appressed epidermal hair and mucilage cells. Physicochemical studies revealed loss on drying (0.6%), total ash (10.75%), acid insoluble ash (0.045%), alcohol-soluble extractive (21.7%), and water-soluble extractive (30.72%). Preliminary analysis for the presence of various functional groups revealed the presence of alkaloids, saponins, phenols and proteins. Thin layer chromatographic study of the alcoholic extract showed the presence of five, six and seven spots in short UV, long UV and after spraying developing reagent, respectively. The information generated by this particular study will provide relevant pharmacognostical and physicochemical data needed for proper identification and authentication of leaves of this particular species.
doi:10.4103/0974-7788.76787
PMCID: PMC3059446  PMID: 21455451
Pharmacognostical study; physicochemical study; thin layer chromatography
3.  Pharmacognostical and Phytochemical Evaluation of the leaves of Bauhinia purpurea Linn. 
Ancient Science of Life  2010;30(2):28-32.
Various pharmacognostic parameters including macroscopy, microscopy, chemomicroscopy and behaviour of powdered drug on treatment with different chemical reagents were studied on the leaves of Bauhinia purpurea Linn. (Family Caesalpinaceae). Phytochemical screening of the plant part with various solvents revealed the presence of phenolic compounds, tannins, flavonoids, phytosterols, saponins and glycosides in it.
PMCID: PMC3336273  PMID: 22557422
4.  Ficus hispida Linn.: A review of its pharmacognostic and ethnomedicinal properties 
Pharmacognosy Reviews  2011;5(9):96-102.
Ficus hispida (FH) Linn. is a moderate sized tree found throughout the year and is grown wild or cultivated for its edible fruits and folklore value. Traditionally, different parts of the plant have been used in the treatment of ulcers, psoriasis, anemia, piles jaundice, vitiligo, hemorrhage, diabetes, convulsion, hepatitis, dysentery, biliousness, and as lactagogue and purgative. FH contains wide varieties of bioactives from different phytochemical groups like alkaloids, carbohydrates, proteins and amino acids, sterols, phenols, flavonoids, gums and mucilage, glycosides, saponins, and terpenes. Various scientific works have been published to establish the scientific basis of traditional medicinal values attributed to FH. Furthermore, newer pharmacological activities like antineoplastic, cardioprotective, neuroprotective and anti-inflammatory effects were also reported recently. Till now, no work has been published to elaborate the pharmacognostic features of FH Linn. The present review is, therefore, an effort to give a detailed account on its pharmacognosy and phytochemistry, and an extensive survey on its pharmacological activities. Moreover, we are trying to establish the mechanism of action behind its earlier reported pharmacology. The review also looks at the future formulation based delivery approaches of its lipophilic bioactives, which is done to enhance its dissolution so as to increase its bioavailability, and thus the associated pharmacological action.
doi:10.4103/0973-7847.79104
PMCID: PMC3210011  PMID: 22096323
Bioavailability; ethnomedicinal properties; extraction method; Ficus hispida; pharmacognosy
5.  Pharmacognostic Standardization, Physico- and Phytochemical Evaluation of Amaranthus Spinosus Linn. Root 
Amaranthus spinosus Linn. (Amaranthaceae) is found throughout India. This tree species has been of interest to researchers because it is a medicinal plant employed in the Indian traditional system of medicine. Pharmacognostic standardization; physico-and phytochemical evaluation of the roots of Amaranthus spinosus was carried out, to determine its macro-and microscopical characters, and also some of its quantitative standards. Microscopical studies were done by using the trinocular microscope. Total ash, water-soluble ash, acid-insoluble ash, sulfated ash values, and alcohol-and water-soluble extractive values were determined for physico-chemical evaluations. A preliminary phytochemical screening was also done to detect different phytoconstituents. Microscopically, the root showed cork, cortex, stellar region, and calcium oxalate crystals. Powder microscopy showed anamalous secondary growth in between the xylem vessels and Calcium Oxalate crystals in the cortex region. Total ash was approximately three times more than acid insoluble and water soluble ash. The ethanol soluble extractive was approximately the same as the water soluble extractive. Thin Layer Chromatography (TLC) of the Petroleum-ether extract using Benzene : Ethyl acetate (6 : 1), showed six spots. In the chloroform extract, using Benzene : Ethyl acetate (4 : 1) nine spots were seen, and in the ethanol extract, using Chloroform: Methanol (93 : 7), only four spots were observed, using Iodine vapor as a viewing medium. Phytochemically, the root exhibited terpenes, alkaloids, glycosides, and sugars. These findings might be useful to supplement information with regard to its identification parameters, which are assumed significant in the way of acceptability of herbal drugs, in the present scenario, which lacks regulatory laws to control the quality of herbal drugs.
doi:10.4103/0975-1483.83770
PMCID: PMC3159276  PMID: 21897662
Amaranthus spinosus Linn.; pharmacognostic standardization; physicochemical evaluations
6.  Pharmacognostic standardization of leaves of Calotropis procera (Ait.) R. Br. (Asclepiadaceae) 
Calotropis procera, belonging to the Asclepidaceae family, is present more or less throughout India and in other warm, dry places such as, Warizistan, Afghanistan, Egypt, and tropical Africa. Its common names are Akra, Akanal, and Madar. The leaves of Calotropis procera are said to be valuable as an antidote for snake bite, sinus fistula, rheumatism, mumps, burn injuries, and body pain. The leaves of Calotropis procera are also used to treat jaundice. A study on Calotropis procera leaf samples extracted the air-dried leaf powder with different solvents such as petroleum-ether (60-80°C), benzene, chloroform, ethanol, and sterile water. Preliminary phytochemical analysis was done long with measurement of the leaf constants, fluorescence characteristics, and extractive values. Quantitative estimation of total ash value, acid insoluble ash, and water- soluble ash may serve as useful indices for identification of the powdered drug. Histochemical studies which reveal rows of cylindrical palisade cells and, vascular bundles may also serve as useful indices for identification of the tissues. These studies suggested that the observed pharmacognostic and physiochemical parameters are of great value in quality control and formulation development of Calotropis procera.
doi:10.4103/0974-7788.59938
PMCID: PMC2876921  PMID: 20532092
Calotropis procera leaves; fluorescence analysis; macroscopy; microscopy; pharmacognostic standardization; phytochemical screening
7.  PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL STUDIES OF ACHYRANTHES ASPERA LINN. 
Ancient Science of Life  2006;26(1&2):1-5.
The whole plant of Achyranthes aspera has been used as remedy for a number of diseases such as dropsy, strangury, cough, kidney stones, dysentery and bowel complaints, According to traditional practice, a kheer prepared from the seeds of this plant is used to treat brain disorders. An attempt was made to fix the macroscopical, microscopical parameters of the leaf quantitative microscopy, physical constants, and behaviour of the powder with chemical reagents and preliminary qualitative phytochemical studies of Achyranthes aspera were investigated. The phytochemical tests revealed the presence of sterols, flavanoids tannins and carbohydrates.
PMCID: PMC3335226  PMID: 22557217
Achyranthes aspera; epilepsy; traditional medicine
8.  Pharmacognostic Studies on the Roots of Baliospermum raziana keshav Et Yog 
Ancient Science of Life  2002;22(2):1-8.
Bailospermum raziana Keshav. Et. Yog. Is a newly identified species belonging to the family Euphorbiaceae. It is a leafy shout monoecious, erect herb. The plant differentiates from the other species i.e Baliospermum montanum (Wild) Muell-Arg by the presence of extra floral nectaries found on the abaxial side all along the margins of the leaf lamina and long peduncled racemes. Histologically the root is differentiated in to periderm and stele. Groups of cortical fibres are randomly distributed among the inner layers of phelloderm. Tanniniferous content and crystals of calcium oxalate are found in the periderm. Simple starch grains are located in the stellar region. Vessel element occurring one at each end. Perforation plates are two in each element occurring one at each end. Phytochemical studies subjected the possibilities of the alkaloids, carbohydrates, flavonoids, triterpenes, tannins etc. The aqueous extract has shown mild purgative action (600 mg /kg body wt) in the animal models. Morphologically there are many similarities between B. raziana and B. montanum an important Ayurvedic herbal drug. In commerce both the drugs are being sold under the common name “Danti’. In the present investigation diagnostic characters of both species have been discussed briefly.
PMCID: PMC3330997  PMID: 22557079
9.  PRELIMINARY PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITES ON THE LEAVES OF Naringi crenulata roxb 
Ancient Science of Life  2005;25(2):53-56.
Ethanolic extract of Naringi crenulata or liminonia crenulata leaves was investigated for Phytochemical and Antimicrobial activities. The macroscopic characteristics of leaves, physical constant values, extractive values, behavior on treatment with different chemical reagents of the powdered leaves. Naringi crenulata were studied to fix some pharmacognostical parameters and preliminary phytochemical studies on ethanolic extracts of the leaves were also performed. Antimicrobial activities against two bacterial strains – Bacillus subtilis, Klebsilla pnemoniae and two fungal strains Aspergillus niger, Mucor sp. among the various leaf extracts maximum antimicrobial activity was exhibited by standard antibiotic.
PMCID: PMC3330901  PMID: 22557191
Naringi crenulata; Rutaceae; Phytochemical studies and Antimicrobial activities
10.  PHARMACOGNOSTICAL INVESTIGATIONS ON TRIPHALA CHURNAM 
Ancient Science of Life  2007;26(3):40-44.
Pharmacognostical and preliminary phytochemical studies of Triphala churnam were carried out. The churnam of triphala consists of equal quantities of deseeded fruits of Terminalia chebula, Terminalia bellerica and Emblica officinalis. Triphala is exclusively used in more than 200 drug formulations in Indian system of Medicine. The present study involved the pharmacognostical evaluation of Triphala, in which morphological and powder microscopical characters were established. In addition, physico-chemical parameters such as ash values viz, total ash (10.21± 0.42), acid insoluble ash (2.54 ± 0.06), water-soluble ash (5.46±0.24) and sulphated ash (13.12 ± 0.63), extractive values viz, alcohol soluble extractive (11.20±0.18)) and water-soluble extractive (52.56±2.04), fluorescent analysis and microchmical tests were determined. The preliminary phytochemical study revealed the presence of carbohydrates, reducing sugar and tannins in aqueous extract and carbohydrates, flavonoids and tannins in alcoholic extract. This standardization would be very much helpful for the identification of Triphala churnam to differentiate from other powdered sources.
PMCID: PMC3330880  PMID: 22557240
11.  Pharmacognostical Evaluation of Caesalpinia sappan Heartwood 
Ancient Science of Life  2003;23(2):100-107.
Caesalpinia span heartwood is used in folklore in India. The present work attempts to summarize the pharmacognostical characters of the heartwood of this plant. Ash and extractive values, phytochemical tests, HPTLC and fluorescence analysis were carried out. The present work contributes for the standardization of this medicinal heat wood.
PMCID: PMC3330961  PMID: 22557119
Caesalpinia sappan; Pharmacognostical evaluation; Phytochemical tests and Fluorescence analysis
12.  Pharmacognostical investigation roots of Monochoria vaginalis presl 
Ancient Science of Life  2008;28(2):7-9.
The present study deals with the macroscpical, microscopical and preliminary phytochemical investigation on Monochoria vaginalis P. The transverse section shows in the root, the presence of cork, cortex, xylem, phloem, pith etc. The diagnostic features of the roots are the presence of fibers associated with vessels, calcium oxalates, and xylem vessel which will help in the identification and authentification process of the drug. Preliminary phytochemical work of the alcoholic extract showed the presence of glycosides, flavonoids and tannins.
PMCID: PMC3336351  PMID: 22557303
13.  Pharmacognostical and preliminary phytochemical studies of Passiflora foetida 
Ancient Science of Life  2008;27(3):19-23.
The plant Passiflora foetida (grandilla) has been used mainly for asthma and various neurological disorders by the traditional medicinal practitioners of Chittor District. Since proper information regarding this plant is not available, our efforts were devoted to fix the pharmacognostical parameters and preliminary phytochemical studies of Passiflora foetid. An attempt was made to fix the macroscopical, microscopical parameters of the leaf, quantitative microscopy, physical constants, behaviour of the powder with chemical reagents and preliminary qualitative phytochemical studies of Passiflora foetida were investigated. The phytochemical tests revealed the presence of sterols, flavanoids and carbohydrates.
PMCID: PMC3330862  PMID: 22557273
Passiflora foetida; depression; traditional medicine
14.  PHARMACOGNOSTICAL AND PHYTOCHEMICAL INVESTIGATION OF PERISTROPHE BICALYCULATA 
Ancient Science of Life  1993;12(3 & 4):420-427.
Morphological, microscopical and phytochemical studies of root and stem of the herb Peristrophe bicalyculata (Acanthaceae) were carried out. Presence of coumarins, alkaloids, potassium chloride (stem and root), saponins and a free sugar (root) have been here in this herb for the first time.
PMCID: PMC3336552  PMID: 22556622
15.  Pharmacognostical evaluation of Barringtonia acutangula leaf 
Barringtonia acutangula (L.) Gaertn. (Family: Lecythidaceae) is an evergreen tree with simple, alternate leaves, long pendulous racemes, dark scarlet flowers, and ellipsoid to ovoid berries containing one ovoid black seed. The present study deals with a detailed pharmacognostical study on the leaf of the crude drug, B. acutangula. Morphoanatomy of the leaf was studied using light and confocal microscopy and World Health Organization (WHO) guidelines on quality control methods for medicinal plant materials. Literature reveals that the phytoconstituents like tanginol, barrinic acid, and barringenic acid are present in the wood and fruits of this plant. Our preliminary phytochemical studies of the powdered leaves revealed the presence of terpenes, flavanoids, carbohydrates, tannins, steroids, and glycosides. The physico-chemical, morphological, histological parameters, and High Performance-Thin Layer Chromatographic (HPTLC) profile presented in this paper may be proposed as parameters to establish the authenticity of B. acutangula and can possibly help to differentiate the drug from its other species and the pharmacognostic profile of the leaves presented here will assist in standardization viz., quality, purity, and sample identification.
doi:10.4103/0974-7788.83189
PMCID: PMC3157107  PMID: 21897641
Barringtonia acutangula; high performance thin layer chromatographic profile; pharmacognosy
16.  PHARMACOGNOSTICAL STUDIES ON MELILOTUS INDICA ALL LEAF 
Ancient Science of Life  1985;4(4):220-223.
The present study deals with the pharmacognostic studies on the leaves of Melilotus indica. The drug shows the presence of tannins, Xanthoprotein, starch, cystine, sterols, triterpenoids, reducing sugars, saponins and alkaloids.
PMCID: PMC3331528  PMID: 22557483
17.  PHYTO-PHARMACOGNOSTICAL INVESTIGATION AND EVALUATION OF ANTI-INFLAMMATORY AND SEDATIVE HYPNOTIC ACTIVITY OF THE LEAVES OF ERYTHRINA INDICA Lam 
Ancient Science of Life  2005;25(2):79-83.
Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components confirming the presence of the indole nucleus. Anti-inflammatory activity was carried out on albino rats. Further, anti-inflammatory activity was compared to that of the standard drug indomethacin and percent inhibition of oedema was determined. Sedative hypnotic activity was also evaluated using pentobarbital which showed mild sedation.
PMCID: PMC3330900  PMID: 22557197
18.  Pharmacognostic parameters for evaluation of the rhizomes of Curcuma caesia 
In ethno medicinal practices, the traditional healers use the genus Curcuma for the treatment of various ailments but Curcuma caesia Roxb. is a very less known and almost untouched drug. The present work attempts to establish the necessary pharmocognostic standards for evaluating the plant material of C. caesia Roxb. Various parameters, such as morphology, microscopy, physicochemical constants, and phytochemical profiles of the entire parts of the plant were studied and the salient diagnostic features are documented. Major chemical constituents, extractive values, physicochemical constants, and other features are also been recorded.
doi:10.4103/2231-4040.79811
PMCID: PMC3217681  PMID: 22171294
Curcuma caesia Roxb.; kali haldi; pharmacognostic; physicochemical constants; phytochemical profile; microscopy
19.  STUDIES ON SOME PHARMACOGNOSTIC PROFILES OF SWIETENIA MACROPHYLLA. King 
Ancient Science of Life  2004;24(2):97-102.
The aerial parts and seeds of Swietenia macrophylla King (Meliaceae) are used in exotic medicine systems. In the present study, a preliminary phytochemical and few pharmacological profiles were under taken. The physical constans, extractive and ash values were examined. The presence of secondary metabolites in the aerial parts and seeds showed that Swietenia macrophylla is a good source of active principles. TLC studies were done by treating dry treating dry powder of Swietenia macrophylla with various acids, iodine and ferric chloride solution and UV and Visible light.
PMCID: PMC3330925  PMID: 22557161
20.  PHARMACOGNOSTICAL STUDIES ON THE LEAVES OF Cassia tora Linn. (FAM. CAESALPINIACEAE) 
Ancient Science of Life  2005;25(2):74-78.
The leaves and seeds of Cassia tora (Family Caesalpinaceae) are used in the treatment of leprosy, ring worm, flatulence, colic, dyspepsia, constipation, cough, bronchitis and cardiac disorders in the Ayurvedic systems of medicine. The present study deals with the study of macroscopic characters of the leaves, ash values, extractive values, behavior on treatment with different chemical reagents and fluorescence characters under ultraviolet light. Preliminary phytochemical studies on different extractives of the leaves were also performed. These studies will help in the identification of the plant for further research.
PMCID: PMC3330902  PMID: 22557196
21.  PHARMACOGNOSTICAL STUDIES ON LEAF OF Coldenia procumbens Linn 
Ancient Science of Life  2002;22(1):67-75.
The plant Coldenia procumbens Linn. is used commonly in Indian system of medicine for various ailments. The present paper deals with detailed pharmacognosy of the leaf of coldenia procumbens Linn. and includes its Macro/Micro morphological (vein islet, vein termination numbers and stomatal index) anatomical characters, Physico chemical standards such as ash values, extractive values, crude fibre content and fluorescence characters of various extracts and leaf powder after treatment with different chemical reagents under UV light. Prelimanary phytochemical tests on various extracts of the leaf have also been carried out.
PMCID: PMC3330985  PMID: 22557078
22.  STUDIES ON SOME PHARMACOGNOSTICAL PROFILE OF FICUS RACEMOSA LINN (FAM. MORACEAE) LEAVES 
Ancient Science of Life  1999;18(3&4):184-191.
The Macroscopic character of the leaves ash values, extractive values, behaviors on treatment with different chemical reagents, fluorescence characters under ultra violet light after treatment with different chemical reagents of the powdered leaves of ficus racemosa Linn (fam. Moraceae) were studied to fix some pharmacognostical parameters. Preliminary phytochemical studies on different extractives of the leaves were also performed. These studies will help in future for identifying this plant for further research.
PMCID: PMC3336477  PMID: 22556888
23.  PHARMACOGNOSTICAL STUDIES ON LEAVES OF ATAIANTIA MONOPHYIA CORREA 
Ancient Science of Life  2003;22(4):129-133.
Leaves of Atalantia monophylla are used in chronic rheumatism and paralysis. The Pharmacognostical studies like histological characters, leaf constants, ash values and extractive values of leaves of Atalantia monophylla Corr were carried out. The preliminary phytochemical analysis were also carried out.
PMCID: PMC3331017  PMID: 22557099
24.  Pharmacognostical and phytochemical evaluation of Vara Asanadi Kwatha 
Ayu  2012;33(1):130-135.
Vara Asanadi Kwatha (VAK) is a compound Ayurvedic formulation prescribed in the management of obesity. Pharmacognostical study counting both macroscopic and powder microscopy of raw drug exposed the quality and genuineness of all the constituents of VAK. Organoleptic features of coarse powder made out of the crude drugs were within the standard range. Specific gravity of the decoction was 1.0185 and pH was 5.5.Total solid content present in the Kwatha was 4.525% w/v, total ash 0.949% w/v, and acid insoluble ash was 0.052% w/v. Iron assay showed the presence of Fe2O3 as 0.065% w/v. Qualitative scrutiny demonstrated the presence of flavonoids and tannis. Thin Layer Chromatography (TLC) and High Performance Thin Layer Chromatography (HPTLC) were carried out after organizing appropriate solvent system in which maximum three spots were distinguished in TLC and nine spots in HPTLC and most of the Rf values were identical when done with different sample extractive methods. This shows the presence of certain definite constituents in the decoction and is helpful for the easy separation of these constituents.
doi:10.4103/0974-8520.100330
PMCID: PMC3456851  PMID: 23049198
HPTLC; Pharmacognosy; TLC; Vara Asanadi Kwatha
25.  PHARMACOGNOSTIC STUDIES ON THE FRUITS OF JATROPHA CURCAS LINN 
Ancient Science of Life  2001;21(2):128-134.
Present paper deals with the pharmacognostic studies of the fruits of J. curcas Linn. The 75-80 cells thick pericarp is differentiated into epicarp, mesocarp and endocarp. Mesocarpic zone embeds non-articulated laticifers, tannin containing idioblasts and randomly distributed vascular bundles. Endocarp shows the occurrence of fibrous sclereids. Preliminary phytochemical screening of the drug powder shows the presence of alkaloids, carbohydrates, glycosides and tannins. Clinical evaluation of the fresh fruit juice has shown it s anti gingivitic property.
PMCID: PMC3336394  PMID: 22557042

Results 1-25 (386562)