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1.  Variation in gymnemic acid content and non-destructive harvesting of Gymnema sylvestre (Gudmar) 
Pharmacognosy Research  2010;2(5):309-312.
Background:
Madhunashini (Gymnema sylvestre R. Br.) commonly known as ‘Gudmar’ in Hindi is an important medicinal climber and extensively used in almost all Indian System of Medicine as a remedy for diabetes, rheumatism, cough, ulcer, jaundice, dyspepsia, constipation, eyes pain and also in snakebite. In India, it is found growing in Andhra Pradesh, Bihar, Chhattisgarh, Karnataka, Kerala, Madhya Pradesh, Maharastra, Orissa, Tamil Nadu, Uttar Pradesh and West Bengal. The major phytoconstituents are gymnemic acids, gudmarin and saponins.
Methods:
In the present study, Gymnema germplasm collected from various regions of Madhya Pradesh was evaluated on the basis of their morphological characteristics and gymnemic acid content. Gymnemic acid content in the leaves was estimated by HPLC. We have also standardized the non-destructive harvesting practices of Gudmar. Selective harvesting was done without harming the main plant. Only mature leaves (60%) were hand plucked in the month of October. Second harvest was done in the month of June.
Results:
Data revealed that gymnemic acid content varied between 0.96% ± 0.03 (Seoni) to 1.58% ±0.03 (Amarkantak). It was also observed that the leaves left at the time of 1st harvest during October matured in June at the time of 2nd harvest.
Conclusion:
Non destructive harvesting practice did not have any negative impact on overall development of the plant. It is evident that there is wide variation in the morphological characteristics and gymnemic acid content in G. sylvestre collected from various locations, which can be exploited for further crop improvement programmes.
doi:10.4103/0974-8490.72330
PMCID: PMC3093035  PMID: 21589758
Cultivation; Gymnema sylvestre; gymnemic acid; non-destructive harvesting
2.  Consensus of the 'Malasars' traditional aboriginal knowledge of medicinal plants in the Velliangiri holy hills, India 
There are many vanishing cultures that possess a wealth of knowledge on the medicinal utility of plants. The Malasars of Dravidian Tamils are an indigenous society occupying the forests of the Western Ghats, South India. They are known to be exceptional healers and keepers of traditional aboriginal knowledge (TAK) of the flora in the Velliangiri holy hills. In fact, their expertise is well known throughout India as evidenced by the thousands of pilgrims that go to the Velliangiri holy hills for healing every year. Our research is the first detailed study of medicinal plants in India that considers variation in TAK among informants using a quantitative consensus analysis. A total of 95 species belonging to 50 families were identified for medicinal and general health purposes. For each species the botanical name, family, local name, parts used, summary of mode of preparation, administration and curing are provided. The consensus analysis revealed a high level of agreement among the informants usage of a particular plant at a local scale. The average consensus index value of an informant was FIC > 0.71, and over 0.80 for some ailments such as respiratory and jaundice. Some of the more common problems faced by the Malasars were gastrointestinal disorders, respiratory illness, dermatological problems and simple illness such as fever, cough, cold, wounds and bites from poisonous animals. We also discovered several new ethnotaxa that have considerable medicinal utility. This study supports claims that the Malasars possess a rich TAK of medicinal plants and that many aboriginals and mainstream people (pilgrims) utilize medicinal plants of the Velliangiri holy hills. Unfortunately, the younger generation of Malasars are not embracing TAK as they tend to migrate towards lucrative jobs in more developed urban areas. Our research sheds some light on a traditional culture that believes that a healthy lifestyle is founded on a healthy environment and we suggest that TAK such as that of the Malasars may serve toward a global lifestyle of health and environmental sustainability.
doi:10.1186/1746-4269-4-8
PMCID: PMC2323365  PMID: 18371206
3.  EDIBLE FRUIT YIELDING PLANTS OF SHEVAROY HILLS IN TAMIL NADU 
Ancient Science of Life  1996;16(2):148-151.
The paper deals with the common edible fruit yielding plants, During the course of medicinal plant survey of shevaroy hills of Eastern ghats. Salem district, Tamil Nadu. Thirty species belonging to 23 genera and 21 families yield edible fruits. They are listed in alphabetical order followed by family, common name and Tamil names.
PMCID: PMC3331147  PMID: 22556784
4.  FOLK-LORE MEDICINES FOR JAUNDICE FROM COIMBATORE AND PALGHAT DISTRICTS OF TAMIL NADU AND KERALA, INDIA 
Ancient Science of Life  1988;7(3 & 4):175-179.
Ethno-botanical explorations with regard to the folk-lore medicine in Coimbatore district of Tamil Nadu and Palghat district of Kerala for jaundice was carried out. Out of twenty remedies thus gathered two are found to be new reports and a few others have got interesting combination. The specimens are identified at Botanical Survey of India, Coimbatore and deposited in the Herbarium of Ethnobiology department of International Institute of Ayurveda, Coimbatore. Two newly reported plants for Jaundice namely Alysicarpus vaginalis DC. and Justicia tranquebariensis L. f, have been taken for phytochemical screening and pharmacological studies. The botanical name of the plant, local name, Sanskrit name and the part of the plant employed are given in table I.
PMCID: PMC3336636  PMID: 22557611
5.  MACROPROPAGATION OF THE INDIAN MEDICINAL PLANT Premna tomentosa Willd 
Ancient Science of Life  2004;23(3):34-36.
Premna tomentosa Willd is a moderate sized deciduous tree of apparently more economic and medicinal values. It is not commonly seen to be used by the medicinemen of Tamil Nadu now-a–days. The plant has been located in the plains and hills of Tamil Nadu, with the help of its varied vernacular names. It is in excessive biotic disturbance. It has been found to be in reproductive isolation, Hence, macropropagation of this plant has been contemplated and tried successfully for the first time. The results are reported.
PMCID: PMC3330966  PMID: 22557130
6.  Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India 
Background
Antimicrobial activity of 18 ethnomedicinal plant extracts were evaluated against nine bacterial strains (Bacillus subtilis, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Ervinia sp, Proteus vulgaris) and one fungal strain (Candida albicans). The collected ethnomedicinal plants were used in folk medicine in the treatment of skin diseases, venereal diseases, respiratory problems and nervous disorders.
Methods
Plants were collected from Palni hills of Southern Western Ghats and the ethnobotanical data were gathered from traditional healers who inhabit the study area. The hexane and methanol extracts were obtained by cold percolation method and the antimicrobial activity was found using paper disc diffusion method. All microorganisms were obtained from Christian Medical College, Vellore, Tamil Nadu, India.
Results
The results indicated that out of 18 plants, 10 plants exhibited antimicrobial activity against one or more of the tested microorganisms at three different concentrations of 1.25, 2.5 and 5 mg/disc. Among the plants tested, Acalypha fruticosa, Peltophorum pterocarpum, Toddalia asiatica,Cassia auriculata, Punica granatum and Syzygium lineare were most active. The highest antifungal activity was exhibited by methanol extract of Peltophorum pterocarpum and Punica granatum against Candida albicans.
Conclusion
This study evaluated the antimicrobial activity of the some ethnomedicinal plants used in folkloric medicine. Compared to hexane extract, methanol extract showed significant activity against tested organisms. This study also showed that Toddalia asiatica, Syzygium lineare, Acalypha fruticosa and Peltophorum pterocarpum could be potential sources of new antimicrobial agents.
doi:10.1186/1472-6882-6-35
PMCID: PMC1621080  PMID: 17042964
7.  Ethnobotanical investigations among tribes in Madurai District of Tamil Nadu (India) 
Background
An ethnobotanical survey was carried out to collect information on the use of medicinal plants in Southern Western Ghats of India (Madurai district, Tamil Nadu). Information presented in this paper was gathered from the paliyar tribes using an integrated approach of botanical collections, group discussions and interviews with questionnaires in the years 1998 – 1999. The informants interviewed were 12 among whom 4 were tribal practitioners.
Results
A total of 60 ethnomedicinal plant species distributed in 32 families are documented in this study. The medicinal plants used by paliyars are listed with Latin name, family, local name, parts used, mode of preparation and medicinal uses. Generally, fresh part of the plant was used for the preparation of medicine.
Conclusion
We observed that the documented ethnomedicinal plants were mostly used to cure skin diseases, poison bites, stomachache and nervous disorders. The results of this study showed that these tribal people still depend on medicinal plants in Madurai district forest areas.
doi:10.1186/1746-4269-2-25
PMCID: PMC1475842  PMID: 16689985
8.  HITHERTO UNREPORTED MEDICINAL USES OF PLANTS FROM KOLLI HILLS 
Ancient Science of Life  1994;13(3 & 4):259-260.
The unreported medicinal uses of these plants from kolli hills, Salem District of Tamil Nadu are presented in this paper.
PMCID: PMC3336523  PMID: 22556657
9.  FOLK HERBAL MEDICINE: A SURVEY ON THE PANIYA TRIBES OF MUNDAKUNNU VILLAGE OF THE NILGIRI HILLS, SOUTH INDIA 
Ancient Science of Life  2005;25(1):21-27.
The present paper represents the results of an ethnobotanical survey conducted in Mundakunnu village of Gudalur taluk, Nilgiri district of Tamil Nadu, India. It has been observed that the plant species are used to various ailments of analgesic, antidiarrhoeal, piles, antidiabetic, gynecological problems, vermifuge, antidandruff, venereal diseases, bone fracture and as vegetables. A total of 52 plants species belonging to 51 genera (33 dicot & 6 monocot) have been discussed.
PMCID: PMC3330892  PMID: 22557184
Mundakunnu; Gudalur Taluk; Paniya Tribes; the Nilgiris; Tamilnadu; ethnobotany
10.  FURTHER NOMENCLATURAL CHANGES IN INDIAN HOMOEOPATHIC MEDICINAL PLANTS 
Ancient Science of Life  1992;11(3 & 4):118-125.
Nilgiri District, Tamil Nadu is one of the most botanised areas of Southern India. In spite of it a number of wild plants had been missed by earlier collectors. Moreover, many exotics and ornamentals having importance in alternative systems of medicine have not been collected and preserved. The present paper lists 34 species of plants used in homeopathy belonging to 31 genera under 23 families.
PMCID: PMC3336595  PMID: 22556573
11.  Spatio-Temporal Dynamics of Caddisflies in Streams of Southern Western Ghats 
The dynamics of physico-chemical factors and their effects on caddisfly communities were examined in 29 streams of southern Western Ghats. Monthly samples were collected from the Thadaganachiamman stream of Sirumalai Hills, Tamil Nadu from May 2006 to April 2007. Southwest and northeast monsoons favored the existence of caddisfly population in streams. A total of 20 caddisfly taxa were collected from 29 streams of southern Western Ghats. Hydropsyche (Trichoptera: Hydropsychidae) were more widely distributed throughout sampling sites than were the other taxa. Canonical correspondence analysis showed that elevation was a major variable and pH, stream order, and stream substrates were minor variables affecting taxa richness. These results suggested that habitat heterogeneity and seasonal changes were stronger predictors of caddisfly assemblages than large-scale patterns in landscape diversity.
doi:10.1673/031.010.4601
PMCID: PMC3014773  PMID: 20572787
diversity; habitat; seasonality
12.  SOME RARE HOMOEOPATHIC MEDICINAL PLANTS OF SOUTH INDIA 
Ancient Science of Life  1993;13(1 & 2):189-196.
This present study describes 11 species under 11 generate and 10 families of rare Homoeopathic Medicinal Plants introduced and cultivated in the Nilgiri district, Tamil Nadu, South India. The original citation, description, distribution and their medicinal uses are given.
PMCID: PMC3336545  PMID: 22556647
13.  A database on endemic plants at Tirumala hills in India 
Bioinformation  2008;2(6):260-262.
Medicinal plants play an important role in health care. The use of medicinal plants for treatment is growing in view of cost and non-compliance of modern medicine as in case of non-communicable diseases. Plants such as Boswellia, ovalifoliolata, Cycas beddomei, Pimpinella tirupatiensis, Pterocarpus santalinus, Shorea thumbuggaia, Syzygium alternifolium, Terminalia pallida are endemic to Tirumala hills of seshachalam range falling under the Eastern Ghats of India. These plants species have medicinal properties such as anti-tumorogenic, anti-microbial, purgative, hypoglycemic, abortificient, analgesic, anti-septic, anti-pyretic and anti-inflammatory. We created a database named DEPTH in an attempt to communicate data of these plants to the scientific community. DEPTH contains data on scientific name, vernacular name, family name, morphological description, economic importance, known medicinal compounds and medicinal importance.
Availability
http://svimstpt.ap.nic.in/MedicinalPlants/mainpage.htm
PMCID: PMC2258430  PMID: 18317578
Tirumala hills; endemic plants; economic importance; medicinal importance
14.  ANTIBACTERIAL EFFICACY AND PHYTOCHEMICAL OBSERVATION OF SOME INDIAN MEDICINAL PLANTS 
Ancient Science of Life  2007;26(3):16-22.
The aim of the study is to evaluate the antibacterial activity of Pistacia integerrima, Cedrus deodara and Gymnema sylvestre against seven different microorganisms such as Escherichia coli, Salmonella typhi, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas, Bacillus subtillis and Staphylococcus aureus by using disc diffusion method. Preliminary studies with ethanol extract and water extract of plants indicated that the growth of test organism was markedly inhibited by ethanol extract of Pistacia integerrima and Gymnema sylvestre. But in case of Cedrus deodara, water extract was more effective. Efficacy of plant extract which showed variable inhibitory activity against each bacteria was compared to standard antibiotic (tetracyclin). The two extracts were subjected to qualitative analysis to find out phytoconstituents present . Results showed that Pistacia integerrima contained all the phytochemicals, so exhibited higher antibacterial activity.
PMCID: PMC3330876  PMID: 22557236
Anti bacterial activity; Pistacia integerrima; Cedrus deodara; Gymnema sylvestre; phytochemical activity
15.  Medicinal plants used by traditional healers in Kancheepuram District of Tamil Nadu, India 
An ethnobotanical survey was undertaken to collect information from traditional healers on the use of medicinal plants in Kancheepuram district of Tamil Nadu during October 2003 to April 2004. The indigenous knowledge of local traditional healers and the native plants used for medicinal purposes were collected through questionnaire and personal interviews during field trips.
The investigation revealed that, the traditional healers used 85 species of plants distributed in 76 genera belonging to 41 families to treat various diseases. The documented medicinal plants were mostly used to cure skin diseases, poison bites, stomachache and nervous disorders. In this study the most dominant family was Euphorbiaceae and leaves were most frequently used for the treatment of diseases.
This study showed that many people in the studied parts of Kancheepuram district still continue to depend on medicinal plants at least for the treatment of primary healthcare. The traditional healers are dwindling in number and there is a grave danger of traditional knowledge disappearing soon since the younger generation is not interested to carry on this tradition.
doi:10.1186/1746-4269-2-43
PMCID: PMC1615867  PMID: 17026769
16.  FOLK MEDICINE OF THE IRULAS OF COIMBATORE FORESTS 
Ancient Science of Life  1997;16(3):222-226.
This paper presents an account of 25 species used by the Irulas of Coimbatore district, Tamil Nadu, as medicinal plants. In addition to scientific name and uses, local name are also given, Medicinal plants and uses hitherto unreported for this tribe alone are given in this paper.
PMCID: PMC3331156  PMID: 22556796
17.  PLANTS USED IN FOLK MEDICINE BY THE KOTAS OF NILGIRI DISTRICT, TAMIL NADU 
Ancient Science of Life  1991;10(4):223-230.
The present report deals with 34 plants of ethno botanical significance used s food and medicine by the Kotas of Nilgiri District, Tamil Nadu. Dietary and medicinal applications of plants re briefly summarized and presented.
PMCID: PMC3331295  PMID: 22556537
18.  Medicinal plants for treatment of diabetes mellitus 
Indian Journal of Clinical Biochemistry  2000;15(Suppl 1):169-177.
Many plants have been used for the treatment of diabetes mellitus in Indian system of medicine and in other ancient systems of the world. Out of these only a few have been evaluated as per modern system of medicine. From many such plants only extracts have been prepared and their usefulness evaluated in experimental diabetes in animals. In some plants likeAllium cepa, Allium sativum, Ficus bengalensis, Gymnema sylvestre, Pterocarpus marsupium etc. active hypoglycemic principles have been isolated and their mechanism of action studied. Most of them seem to act directly on pancreas (pancreatic effect) and stimulate insulin level in blood. Some have extra pancreatic effect also by acting directly on tissues like liver, muscle etc. and alter favourably the activities of the regulatory enzymes of glycolysis, gluconeogenesis and other pathways. Since the plant products have less side effects, they have the potential as good hypoglycemic drugs. They may also provide clues for the development of new and better oral drugs for diabetes.
doi:10.1007/BF02867556
PMCID: PMC3454085  PMID: 23105280
Medicinal plants; Hypoglycemic agents; Diabetes mellitus
19.  Pharmacognostical study of Tamalaki (Phyllanthus fraternus Webster), a herb used in Tamaka-svasa 
Ayu  2011;32(3):398-401.
Tamalaki is a herbacious medicinal plant, described in Ayurvedic texts in many occurrences with different properties, actions, uses and synonyms, supposed to indicate more than one species commonly used in practice. Modern scholars mostly suggest Phyllanthus fraternus Webster (syn. P. niruri Linn.), P. amarus Schum. and Thonn. and P. urinaria Linn. as the source plants of Tamalaki. In this study, an attempt has been made to designate P. fraternus as the source plant of Tamalaki used in the treatment of Tamaka-svasa (Bronchial asthma) and other respiratory disorders by analyzing therapeutic uses, actions, properties, taste, synonyms as well as pharmacognostical characters. Smooth capsule, six tepals, less and short fibrous root, pentagonal outline with wing-shaped young stem are some of the specific characters observed in this species.
doi:10.4103/0974-8520.93924
PMCID: PMC3326891  PMID: 22529659
Ayurveda; pharmacognosy; phyllanthus; synonyms; tamalaki
20.  In Vitro Conservation of Twenty-Three Overexploited Medicinal Plants Belonging to the Indian Sub Continent 
The Scientific World Journal  2012;2012:929650.
Twenty-three pharmaceutically important plants, namely, Elaeocarpus spharicus, Rheum emodi, Indigofera tinctoria, Picrorrhiza kurroa, Bergenia ciliata, Lavandula officinalis, Valeriana wallichii, Coleus forskohlii, Gentiana kurroo, Saussurea lappa, Stevia rebaudiana, Acorus calamus, Pyrethrum cinerariaefolium, Aloe vera, Bacopa monnieri, Salvia sclarea, Glycyrrhiza glabra, Swertia cordata, Psoralea corylifolia, Jurinea mollis, Ocimum sanctum, Paris polyphylla, and Papaver somniferum, which are at the verge of being endangered due to their overexploitation and collection from the wild, were successfully established in vitro. Collections were made from the different biodiversity zones of India including Western Himalaya, Northeast Himalaya, Gangetic plain, Western Ghats, Semiarid Zone, and Central Highlands. Aseptic cultures were raised at the morphogenic level of callus, suspension, axillary shoot, multiple shoot, and rooted plants. Synseeds were also produced from highly proliferating shoot cultures of Bacopa monnieri, Glycyrrhiza glabra, Stevia rebaudiana, Valeriana wallichii, Gentiana kurroo, Lavandula officinalis, and Papaver somniferum. In vitro flowering was observed in Papaver somniferum, Psoralea corylifolia, and Ocimum sanctum shoots cultures. Out of 23 plants, 18 plants were successfully hardened under glasshouse conditions.
doi:10.1100/2012/929650
PMCID: PMC3349164  PMID: 22593711
21.  AN ETHNIC METHOD OF MILK CURDLING USING PLANTS 
Ancient Science of Life  1996;16(1):60-61.
Plants used for curdling of milk practiced by kollimalayalis, the tribes of kolli, hills, Salem District, Tamil Nadu are discussed.
PMCID: PMC3331141  PMID: 22556771
22.  PRELIMINARY SURVEY OF WILD EDIBLES OF KOLLI HILLS OF SALEM 
Ancient Science of Life  1992;11(3 & 4):133-136.
This paper presents an account of 25 species used by Kollimalayalis of Kolli hills, Salem District, Tamil Nadu, as wild edibles in detail, including vernacular name and plant parts used.
PMCID: PMC3336603  PMID: 22556576
23.  PHARMACOGNOSTICAL AND PHYSICOCHEMICAL CHARACTERISTICS OF ROOTS OF LESSER KNOWN MEDICINAL PLANT CAESALPINIA DIGYNA ROTTL 
Ancient Science of Life  2007;26(3):35-39.
Caesalpinia digyna Rottl. (Caesalpiniaceae) is shrubby perennial climber found in Eastern Ghats. Roots are astringent and used in Ayurveda and Unani systems of medicines. Bergenin, Caesalpinine A and Caesalpinine C were isolated from the roots. However, this medicinal plant has not been studied pharmacognostically. Hence, the present investigation reports pharmacognostical and physicochemical properties of roots of Caesalpinia digyna.
PMCID: PMC3330874  PMID: 22557239
Caesalpinia digyna; Caesalpiniaceae; Pharmacognosy; Physicochemical properties; Ayurveda
24.  A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity 
This review focuses on the efficacy and safety of effective herbal medicines in the management of obesity in humans and animals. PubMed, Scopus, Google Scholar, Web of Science, and IranMedex databases were searched up to December 30, 2008. The search terms were “obesity” and (“herbal medicine” or “plant”, “plant medicinal” or “medicine traditional”) without narrowing or limiting search elements. All of the human and animal studies on the effects of herbs with the key outcome of change in anthropometric measures such as body weight and waist-hip circumference, body fat, amount of food intake, and appetite were included. In vitro studies, reviews, and letters to editors were excluded. Of the publications identified in the initial database, 915 results were identified and reviewed, and a total of 77 studies were included (19 human and 58 animal studies). Studies with Cissus quadrangularis (CQ), Sambucus nigra, Asparagus officinalis, Garcinia atroviridis, ephedra and caffeine, Slimax (extract of several plants including Zingiber officinale and Bofutsushosan) showed a significant decrease in body weight. In 41 animal studies, significant weight loss or inhibition of weight gain was found. No significant adverse effects or mortality were observed except in studies with supplements containing ephedra, caffeine and Bofutsushosan. In conclusion, compounds containing ephedra, CQ, ginseng, bitter melon, and zingiber were found to be effective in the management of obesity. Attention to these natural compounds would open a new approach for novel therapeutic and more effective agents.
doi:10.3748/wjg.15.3073
PMCID: PMC2705729  PMID: 19575486
Animal; Herbal medicine; Human; Obesity
25.  Review on Medicinal and Pharmacological Properties of Iresine Herbstii, Chrozophora Rottleri and Ecbolium Linneanum 
India has a rich tradition of plant-based knowledge on healthcare. A large number of plants/plant extracts/decoctions or pastes are equally used by tribals and folklore traditions in India for treatment of cuts, wounds and burns. The resistance of the microorganism has increased due to the indiscriminate use of commercial antimicrobial drugs commonly used for the treatment of infectious diseases. Resistance to antimicrobial agents has resulted in morbidity, mortality, from treatment failures and increased health care costs. There is an urgent need to discover novel, effective plant-based antimicrobial drug to the increasing problem of drug resistance. This situation forced the scientist to search for new antimicrobial substances from various sources including medicinal plants. Iresine herbstii, Ecbolium linneanum , Chrozophora rottleri have been used in folk remedies and is reported to have a broad range of therapeutic effects. Therefore this paper attempts to bridge the lacunae in the existing literature and offers immense scope for researchers engaged in validation of the traditional claims and development of safe and effective therapeutic agent.
doi:10.4314/ajtcam.v8i5S.6
PMCID: PMC3252720  PMID: 22754065
Medicinal plants; Iresine herbstii; Ecbolium linneanum; Chrozophora rottleri; Medicinal properties

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