Pratishyay basically is a Vat-kaphaj disorder arising from accumulation of vitiated Vat along with kaph-pitta-rakta in uttamang (shirh pradesh) and comparable to Rhinitis which describes a group of symptoms including runny nose, stuffiness, sneezing usually due to common cold, environmental irritants and immunodeficiency. This study aim to do 1. Evaluation of effectiveness of Vyoshadi gutika (samshaman therapy) and Pippalayadi churna Avapida nasya (samshodhan therapy) in the management of pratishyay, 2. Statistical assessment of data post treatment.
60 patients of Pratishyay aged between 16-60 years of age of both sexes complaining of Rhinorrhoea/ nasal block, sneezing, heaviness of head, anosmia were selected randomly and assigned for clinical study were divided into 2 groups. Group A consisting of 30 patients had internal administration of Vyoshadi gutika in a dose of 2 tablets QID (each tab. 375 mg) with lukewarm water for 30 days. Group B-30 patients took Vyoshadi gutika along with Pippalayadi churna Avapida nasya (6 drops in each nostril early morning) for duration of 21 days. All patients were advised to attend 15 days Intercal regularly for 3 months for assessment of disease through subjective and objective parameters.
60% patients (18 no.) of Group B while 47% patients (14 no.) Group A responded satisfactorily with maximum improvement (more than 76% symptomatic improvement). Similarly, Moderate improvement (between 51-75%) was seen in 47 patients of Group A and 37% of Group B while mild improvement in 10% and 3% patients of Group A and B respectively. No untoward adverse effects were seen in any patients.
It can be concluded that on the basis of Practical, Therapeutic and Statistical analysis, patients of both groups got satisfactory improvement. Besides, patients treated with both Samshodhan Nasya therapy and Samshaman Vyoshadi Gutika therapy comparatively got better results.
Application of Madhu (honey) is one among the Shashthi Upakrama (sixty treatment modalities) described by Sushruta. Clinical observation has shown its effectiveness in treatment of Dushta Vrana (chronic wounds). We report a case of Dushta Vrana on the anterior aspect of the right leg that was treated successfully with local application of Madhu and Neem (Azadirachata indica) bark decoction.
Dushta Vrana; Madhu; Neem bark; Shashthi Upakrama
Myopia, commonly referred to as shortsightedness, is the most common eye disease in the world with substantial social, educational, and economic impact. Some of the clinical features of Timira can be correlated with myopia. An open randomized clinical trial was conducted to evaluate the role of Tarpana with and without Nasya in patients suffering from myopia. In total, 41 patients were registered in two groups, out of which 30 patients completed the treatment. In Group A, Tarpana with Mahatriphaladya Ghrita and in Group B, Nasya with Abhijita taila followed by Tarpana with Mahatriphaladya Ghrita was administered. After enrollment of the patients in the study, the cardinal signs and symptoms of Timira — myopia, that is, visual acuity, clinical refraction, were evaluated before and after the treatment. Comparatively, more relief in the signs and symptoms were found in the Nasya group followed by the Tarpana group.
Timira; Myopia; Mahatriphaladya Ghrita; Abhijit Taila; Tarpana; Nasya
Thirty patients suffering from uncomplicated chronic Sinusitis were enrolled in a clinical study to asses the efficacy of Ayurvedic medicine comprising of Tribhvan kirti rasa (Tablet) along with inhalation of steam of Dasamulakwath (Decoction) followed by nasya (intranasal instillation) with Anu tailam. The Tribhuvan kirti rasa was administered at a dose of 250mg b.d with Adrak swaras (Juice of Ginger).Steam inhalation of Dasmula kwath was given two times a day followed by nasya of Anu tail at a dose of 4 drops in both nostrils. The duration of the treatment varied from 45 days to 90 days. Radiological tests were done periodically. The patients were examined clinically in every week to asses the effect of medicine. The overall clinical efficacy was 96.6%. This medicine along with steam inhalation followed by Nasya was found to be well tolerated in general and no side effects were reported. Hence this treatment could be recommeed for treatment of chronic Sinusitis.
From ancient to modern times, the perspective to visualize the management of Madhumeha (DM) has shifted from holistic to drug oriented. Therefore, until a few years ago, the revival of the holistic approach, the Ayurvedic diet, and lifestyle were not being much focused. This research work was planned to evaluate the extra effects of Ayurvedic Ahara and Vihara in the management of Madhumeha and to project them socially. A total of 30 patients were selected and divided into two groups. Group A was treated with Ayurvedic Ahara and Vihara with Varadi Kwatha and group B was treated with only Varadi Kwatha for 8 weeks. The study showed highly significant results in most of the parameters in both the groups. However, further trials with increased number of patients are needed to support the current observations.
Ahara; Diabetes Mellitus; diet; lifestyle; Madhumeha; Varadi Kwatha; Vihara
Description of Vandhyatva is available in most of the Ayurvedic classics, including Nidana (diagnosis), Samprapti (etiopathogenesis), Lakshana (symptomatology), Bheda (types) and Chikitsa (treatment). In current study, efforts have been made to study the effect of Nasya and Matra Basti on anovulation (Beeja Dushti). Ovulation is under the control of Vata. Narayana Taila is attributed for its effect in Vandhyatva. 24 patients of female infertility having anovulatory factor, being diagnosed by Trans-Vaginal Sonography (TVS) for 2 consecutive cycles were divided in two groups. Patients in Group A (n = 12) administered the drug through Nasya and in Group B (n = 12) through Matra Basti. Ovulation occurred 36.36% of patients in group A and 66.16% of patients group B. Matra Basti showed better results than Nasya group on anovulation.
Anovulation; infertility; Matra Basti; Narayana Taila; Nasya; Vandhyatva
Microalbuminuria is the strong predictor of diabetic nephropathy, which is the main cause of morbidity and mortality in patients with diabetes mellitus (DM). Microalbuminuria is also characterized by increased prevalence of arterial hypertension, proliferative retinopathy, and peripheral neuropathy. The study was planned to evaluate the effect of Gokshura-Punarnava Basti in the management of microalbuminuria in DM (Madhumeha). Eligible diabetic patients with urine albumin excretion between 30 and 300 mg in 24 h were randomly divided into two groups. Asthapana Basti (decoction enema) of Gokshura and Punarnava Kwatha (decoction), Kalka (paste), Taila (medicated oil), Madhu (honey), and Saindhava (rock salt) for 6 consecutive days and Anuvasana (unctuous enema) of Gokshura-Punarnava Taila on 1st and 8th day by traditional Basti Putaka method was given in study group. Tablet Enalapril 5 mg, twice daily for 30 days was given to the patients in control group. The primary outcome measures were percentage change in the presenting complaints of diabetes, urine microalbumin, Blood Sugar Level (BSL), and Blood Pressure (BP). Enalapril showed 33.33% improvement, where as Gokshura-Punarnava Basti showed 79.59% improvement in the presenting complaints of diabetes, urine microalbumin, BSL and BP. Gokshura-Punarnava Basti has shown superior results in the management of microalbuminuria in DM as compared to control drug.
Basti; diabetes mellitus; Gokshura; Madhumeha; microalbuminuria; Punarnava1
The smooth and glowing complexion of face increases the beauty of a person and also gives tremendous self-confidence. Vyanga is a disease which decreases the glowing complexion of face and affects the skin. Even though it is considered as kshudra roga (minor disease), it has got a major importance as a cosmetic problem in the society. It is characterized by the presence of painless and bluish-black patches on face. Treating this condition has become a problem, since safe drugs are not available for long term therapy. So the study was aimed to evaluate the efficacy of Arjunatwak lepa with Madhu and Panchanimba churna internally.
For clinical study, 30 clinically diagnosed patients were registered and divided into two groups with 15 patients in each group. In Group-A patients were administered with Arjunatwak lepa with Madhu for 21days. In Group-B patients were administered with both Arjunatwak lepa with Madhu and Panchanimba churna internally for 21days
In Group A, out of 15 patients, 09 patients were cured completely, which was statistically significant at the level of p<0.01. 4 patients have shown marked improvement, 2 patients showed slight improvement. In Group B, out of 15 patients, 12 patients had attained normal skin color, which was statistically highly significant at the level of p<0.001, 1 patient had mild improvement, 2 patients have moderate improvement. Statistically significant result was obtained in symptom bluish-black patch over the face. The clinical study has shown that combined therapy in Group-B gives better results than topical treatment.
From the observations and results of this study, it can be concluded that combined therapy using Arjunatwak lepa along with Panchanimba churna have provided better results in depigmentation of the patches seen in Vyanga roga than local therapy.
A comparative clinical study was conducted on the management of Diabetic Retinopathy (DR) with Doorvadya Ghrita Tarpana and Mahavasadi kwatha internally. The main aim and objective of the study was to evaluate the efficacy of Doorvadya ghrita Tarpana and Mahavasadi kwatha internally, when used individually and as an adjuvant.
The patients were randomly divided in 3 groups with 15 patients in each group. Group A: Tarpana with Doorvadya Ghrita for 3 sittings, 5 days in each sitting, with a gap of 11 days after each sitting, total 48 days duration. Group B: Mahavasakadi Kwatha Pana with 50ml dose every day in the morning, empty stomach, for 48 days. Group C: Both Doorvadya Ghrita Tarpana and Mahavasakadi kwatha pana, for 48 days.
All the three groups have shown statistically significant results. Group B and C have shown better response as compared to Group A. Moreover Group B has shown slightly better response as compared to Group C.
The study showed that microaneurysms, intra retinal haemorrhages, exudates are best managed by treatment with Group-B; where as blurred vision responded better to combine treatment of Group-C. Other parameters like neovascularization did not produce any significant result in any of the groups. Hence Ayurvedic management definitely prevents further progression of the Diabetic Retinopathy and its complications.
Considering high prevalence and the need to look for alternative medicine, essential hypertension was screened in light of Vata–Pitta Pradhana Rakta Pradoshaja Vikara as mentioned by Acharya Charaka. Comparing the etiological factors, symptomatology, and complications with Rakta Pradoshaja Vikara with that of essential hypertension, a striking similarity was revealed. To prove the practical approach of management of Vata–Pitta Pradhana Rakta Pradoshaja Vikara, a randomized open clinical trial on 33 uncomplicated subjects of essential hypertension was conducted. The subjects were allotted in two groups, viz. (Group A) Virechana group having 16 cases who underwent Virechana Karma by Trivrita, Aragvadha, Eranda Taila, and Draksha Kwatha as Sahapana; and (Group B) Basti group consisting of 17 cases who were administered Dashmoola Kala Basti in which Niruha with Dashmoola Kwatha and Anuvasana with Dashmoola Taila was done. Patients of both the groups were followed by Shamana Chikitsa (Arjunadi Ghanavati). The overall effect of the therapies on systolic and diastolic blood pressure showed that Virechana proved better relief (43.75%) as compared to Basti (29.41%). The response was encouraging and has created scope for further studies.
Basti Karma; essential hypertension; Raktapradoshaja Vikara; Virechana Karma
Poly Cystic Ovarian Disease (PCOD) is a complex disorder affecting 5-15% women in their reproductive age and related to ovarian dysfunction, characterized by menstrual irregularities, hyperandrogonism, obesity, and infertility. In Ayurveda, these symptoms are found under various conditions, caused by vitiated Vata and Kapha. Pathadi Kwatha and Shatapushpa Taila Matra Basti were studied in the current attempt to evaluate their comparative efficacy in cases of PCOD. Total 34 patients of PCOD were registered among which, 32 had completed the treatment of 2 months. They were randomly divided in to three groups. In group A Pathadi Kwatha (10 g, bid) and Shatapushpa Taila Matra Basti (60 ml for 7 days after cessation of menses for 2 consecutive cycles) were administered. In group B only Basti, whereas in group C capsules of roosted wheat flour were administered. Better results were obtained in group A especially in menstrual irregularities, achieving follicular growth and in weight reduction.
Artavavaha Srotas; Matra Basti; ovarian functions; Pathadi Kwatha; PCOD; Shatapushpa Taila
A study has been designed to evaluate the effectiveness of Dashanga Kwatha Ghana Vati in Urdhwaga Amlapitta (non-ulcer Dyspepsia). Randomized single blind, placebo controlled study was conducted in 138 patients attending O.P.D. of department of Basic Principles, I.P.G.T. and R.A., Gujarat Ayurved University, Jamnagar, and grouped into two. Both the groups consumed two tablets of either Dashanga Kwatha Ghana Vati or placebo, twice daily after food for a period of eight weeks. The patients were followed upto four weeks, 110 patients had completed the treatment and no adverse effects were reported during the treatment. Both groups had improved in the clinical symptoms and overall statistical significance was observed in the differences of scores between the two groups.
Dashanga Kwatha Ghana Vati; non-ulcer dyspepsia; Urdhwaga Amlapitta
The purpose of the present study was to evaluate the diuretic activity of Veerataru [Dichrostachys cinerea (Linn.)] Kwatha in experimental animals by following the standard procedure. Randomly selected animals were divided into three groups of six animals each. The root of Veerataru was administered orally in the form of Kwatha at a dose of 5.4 and 10.8 ml/kg. Parameters like volume of urine, pH of urine and urinary electrolyte concentrations like sodium, potassium and chloride were studied. Veerataru Kwatha increased the urine output in a dose-dependent manner. However, it did not affect the urinary electrolyte concentrations. From the present study, it can be concluded that the root of Veerataru has diuretic property.
Dichrostachys cinerea; diuretic activity; Veerataru Kwatha
Amlapitta is a very common disease caused by Vidagdha Pitta with features such as Amlodgara, Hrid Kantha Daha, and Avipaka. This is a burning problem of the society. Irregular and improper food habits, and busy stressful lifestyle is one of the main culprit. Amlapitta is the GI disorder described in Ayurvedic texts that closely resembles with Gastritis in modern science. In chronic stage, it may lead to ulcerative conditions. In this study, total 41 patients were registered and were randomly divided into two groups. In group A, Shatapatrayadi
churna tablet and in group B Patoladi Yoga tablet were given for 1 month. The Nidana, signs, and symptoms were observed carefully to get idea about the Samprapti of the disease. The effect of Patoladi Yoga on Roga Bala is 65.79%, 62.11% on Agni Bala, and 63.35% on Deha and Chetasa bala. The overall relief was 63.75%. The effect of Shatapatrayadi tablet on Roga Bala was 71.94%, 73.15% on Agni Bala, and 77.68% on Deha and Chetas Bala. The overall relief was 74.25%.
Amlapitta; gastritis; Patoladi yoga; Shatapatrayadi churna
This work was designed to assess the efficacy of Nasya in reducing the signs and symptoms of cervical spondylosis. The patients attending the O. P. D of Department of Kaya Chikitsa and Panchakarma, Government Ayurveda College Hospital, Thiruvananthapuram were enrolled and subjected to the treatment schedule. Total duration of treatment was 21days. The schedule for the first 14 days was similar in both the groups. It included Rooksha Sveda for 7days followed by Patra Pottali Sveda for 7days. During this period, 90 ml Gandharvahastadi Kashaya twice and Guggulu Tiktaka Kashaya once were given internally. After this, in the Nasya group Nasya was done for 7days with Dhanwantaram Tailam (21times Aavartita), Mridu
Paka in Madhyama Matra (8Bindu). Along with this Guggulu Tiktaka Kashaya was given thrice. In the control group, Guggulu Tiktaka kashaya alone was given thrice daily. Assessments were done with regard to pain, tenderness, radiation of pain, numbness, range of movements and hand grip strength. These were done before treatment, before nasya, after treatment and after 1month follow-up. The statistical hypothesis was tested using paired ‘t’ test and ‘Z’ test for proportion. The trial proved that conventional management along with Nasya was more efficacious than conventional management alone in reducing the signs and symptoms of cervical spondylosis.
Cervical spondylosis; Gandharvahastadi Kashaya; Guggulu Tiktaka Kashaya; Nasya
According to Sushruta, disease in which plaque formed on teeth and hardened by the action of deranged Vayu, lies in a crystallized form at root of teeth is called as Dantasharkara. According to Vagbhata, accumulation of dirt on teeth by not cleaning them daily or of Kapha dehydrated by Vata adhering to the teeth, becoming hard and emits bad odor is known as Dantasharkara (Tartar). Tartar manifests as a deposit of inorganic salts composed primarily of calcium carbonate and phosphate mixed with food debris, bacteria and desquamated epithelial cells which reduce the quality of whiteness and strength of the teeth. Teeth loss is also not uncommon in tartar sufferers. Such deposits tend to destroy the healthy growth and function of teeth. It should be removed in such a way as not to hurt the roots of the teeth and then parts should be rubbed (Pratisarana) with Laksha Churna and Madhu. In trial group, management of tartar is attempted by local rubbing of Laksha Churna with Madhu on the surface of teeth and gingiva. Regeneration, repair and new attachment are the aspects of periodontal healing that are achieved by gingival physiotherapy on scaling wound. Pratisarana of Laksha Churna with Madhu is easy to apply, cost effective and free from side effects in comparison to systemic use of modern drugs.
Dantasharkara; Laksha Churna; Madhu; Pratisarana; Vranaropaka
Shitada is one of the Dantamulagata Rogas mentioned by Acarya Susruta under the heading of Mukha Rogas. It is characterized by symptoms like spontaneous bleeding, halitosis, blackish discoloration of gums, and so on. The symptomatology of Shitada can be compared with gingivitis, which is caused mainly by the accumulation of debris, plaque, and calculus at the tooth margin due to ignorance of oral care. It can progress into periodontitis – the disease in which the firmness, contour, and position of the gums are altered and teeth become mobile. The prevalence of gingivitis is as high as 50% in most of the population. In the present study, a total of 33 patients were registered in three groups. Bhadramustadi yoga has been used in paste form for local application along with Nagaradi Kwatha Gandusa in Group A and in powder form for Pratisarana along with Nagaradi Kwatha Gandusa in Group B. In Group C (Control) Sphatika Jala was used. The patients were diagnosed and assessed on the basis of Ayurvedic as well as modern classical signs and symptoms. Further assessment was done with the different indices used in modern dentistry. All the signs and symptoms were given a score depending upon the severity, to assess the effect of the drugs objectively. The effect of therapy was highly significant in group A in most of the signs, symptoms, and indices; and in group B it was highly significant in some signs and symptoms.
Bhadramustadi yoga; bleeding gums; Dantamula; Gingivitis; Nagaradi Kwatha; oral hygiene; Shitada
Ankylosing spondylitis belongs to a group of rheumatic diseases known as the spondyloarthropathies (SpA), which show a strong association with the genetic marker HLA-B27. Inflammatory back pain and stiffness are prominent early in the disease, whereas chronic, aggressive disease may produce pain and marked axial immobility or deformity. Modern medicine has no established treatment for it. From the Ayurvedic perspective, the disease can fall under amavata, which may be effectively managed when intervention is started in its early stages. Niruha basthi with Balaguduchyadi yoga, combined by Shamana treatment with Rasnerandadi kwatha and Simhanada guggulu have been found effective in curbing its progression. This article presents a single case report in which these treatments achieved considerable success.
Amavatha; ankylosing spondylitis; HLA B27; niruha basthi
Klaibya (Male Sexual Dysfunction = MSD) is common among men of all ages, it has been recently estimated that more than 152 million men worldwide experienced sexual dysfunction in 1995, and that this number will rise by 170 million, to approximately 322 million by the year 2025. In the past years, it has been reported that most of the hypertensive patients having disability to perform sexual acts and comes under the MSD. To keep these facts in mind the present study aimed to evaluate the efficacy of the Gokshuradi Vati in the management of Klaibya with or without hypertension.
The patients identified and classified as suffering from klaibya with or without hypertension participated in the clinical trial in three groups. The trial drug Gokshuradi Vati (Su.) 2 tabs of 500 mg with anupana of GOKSURADI KWATHA 10 ml. was be administered to all the patients for 1 month. All the Patients were assessed on the basis of subjective and objective criteria.
The results showed statistically significant improvement in high blood pressure. Beside these, highly significant improvement was found in sperm count, serum testosterone level and IIEF-15 variables.
On the basis of the results this study concluded that hypertension and klaibya are having a strong relation in each other's pathogenesis. On the basis of our study, we can say that every patient of hypertension should be examined for Klaibya.
Apabahuka is a disease that usually affects the Amsa sandhi (shoulder joint).It is produced by the Vata dosha. Even though the term Apabahuka is not mentioned in the nanatmaja Vata vyadhi, Acharya Sushruta and others have considered Apabahuka as a Vataja vikara. Amsa shosha (wasting of the shoulder) can be considered as the preliminary stage of the disease, where loss or dryness of sleshaka kapha from amsa sandhi occurs. For the present study, Marsha nasya with Laghumasa Taila was administered to 15 patients for seven days, and the following results were obtained. After treatment, 53.33% relief was found on Bahupraspandita hara, 26.66% on Shoola, 30.00% on Stambha, 60.00% on Atopa, and 37.50% on wasting of muscles. On the overall effect of therapy alone, one (6.60%) patient got marked improvement, eight (53.33%) got moderate improvement, four (26.66%) were improved, and two (13.33%) patients remained unchanged.
Apabahuka; Marsha nasya; Laghumasa Taila; Vata vyadhi; Amsa shosha; Abhyanga; Swedana; Snehapana
Greeva Stambha (A Vataja Disorder) simulates cervical spondylosis, which is a chronic degenerative condition of the cervical spine. Keeping in view the increasing incidence of this problem in modern society with more of desk- workers; an observational study was conducted on 22 patients of Greeva stambha vis-a-vis cervical spondylosis selected from OPD/IPD of CRIA, Punjabi-Bagh, New-Delhi, satisfying the inclusion criteria. The Vatahara treatment viz. Maha Yogaraj Guggulu 500 mg BD, Panchguna tail for local use and Nadi sweda (Local steam with Dashmoola Kwatha) were given for seven days. The results were assessed on the basis of symptomatic improvement using visual analog scale.
Cervical spondylosis; Greeva Stambha; Nadi Sweda; Panchguna Tail; Vatahara; visual analog scale; Yogaraj Guggulu
The disease Amavata can be presented as very similar to Rheumatoid Arthritis. Rheumatoid Arthritis is chronic in nature and affects mostly middle aged people. For this disease there is no satisfactory medicine is available till date. But in Ayurveda there are many drugs described for Amavata which are cost effective and easily available with no side effects. The present clinical study evaluated the effect of Chitrakadi Churna and Kshar Basti in the management of Amavata.
30 clinically diagnosed patient of Amavata were registered and completed the trial. In this 15 patients (Group A) administered Chitrakadi Churna 4gm twice daily with lukewarm water after meal. Another 15 patients (Group B) administered Chitrakadi Churna 4gm twice daily with lukewarm water after meal and Kshar Basti as per Kalbasti krama i.e 16days followed by local Snehan Swedan.
Results of this trial were encouraging as there is improvement in each symptom of patient like pain, stiffness, swelling, and tenderness. Group A in which only Chitrakadi Churna was administered there was no significant improvement seen statistically. But Group B in which Chitrakadi Churna as well as Kshar Basti was administered highly significant improvement seen statistically. Details of the Statistical test and other important will be discussed at the time of paper presentation.
From present clinical trial it is concluded that this therapy is very useful for pain, swelling, tenderness and stiffness, which were chief complaint of the patient. Chronicity more than 3 years did not show marked improvement. And also this drug is supposed to be very good combination of Vedanashamaka, Shothaghna, Amapachaka Dravyas. No untoward effects were seen except mild loss of weight.
APAKARSHAN CHIKITSA SIDDHANT: ‘Punarapi Apakarshan’ Ashtang Sangrah 12/6; ‘Apakarshan……’ Charak Viman 7/28. Vyanga Vyadhi Described under Kshudra Roga in various Samhita's. The objective is To study the sign & symptoms of Vyanga. To study the efficacy of Triphala Kwatha on vyanga under the siddhant Apakarshana chikitsa.
30 patient were taken govt. Ayurved College, Nagpur, Dravyaguna OPD. Drug Triphala Kwatha for Virechanartha. Dose decided as per mrudu, madhyam, krura kostha.
Duration: 1 to 2 months. Criteria of Assessment 30 patients were taken and chloasma was measured & scored (4 0) before treatment and after (1 &2 months) treatment. This data is presented in table. Following gradation were decided: 4 Very Severe dark circle; 3 Severe dark circle; 2 Moderate dark circle; 1 Mild dark circle; 0 Relived dark circle. The data is completely non parametric in nature and symptom severity is a desecrate variable. For coloration distribution is polynomial and so Wilcoxon Signed Rank Test was applied which is equivalent to paired “t test” of parametric analysis.
Details of statistical analysis of our data is presented below. Vyanga dark circle. Total score of Lakshana before starting the treatment = 89. After first Virechan Karma the total Lakshana score = 89 (0%). After Second Virechan Karma the total Lakshana score = 61(31.46%). After 7 days of second Virechan Karma the total Lakshana score = 61(31.46%) Mean observed second virechan karama as well as 7 days after second virechana karama = 2.0333. The S.D. of this data = 0.8087. Z= 5.112b. P. Value of this data (p < 0.05)
The data shows significant (p < o.05); After Triphala Kwatha Virechan within 1 months p > 0.05; Triphala Kwatha Virechan after 2 month p < 0.05; Significant result found after 2 month.
Whereas sexual function has long been assumed to be an important component of adult men's lives, the impact of sexual dysfunction has not been estimated in parallel to other modern disease entities. We compared the seriousness of erectile dysfunction (ED) with that of other diseases by use of self-administered questionnaires.
Materials and Methods
Between January 2012 and July 2012, 434 healthy male volunteers (group 1) and 263 ED patients (group 2) were enrolled. The questionnaire consisted of the following: "If you must undergo only one disease in all your life, which disease could you select among these items or ED?" The comparative disease entities included hypertension, diabetes mellitus (oral hypoglycemic agent/insulin injection), hemodialysis, myocardial infarction, herpes zoster, chronic sinusitis, chronic otitis media, gastric cancer (early/late), lung cancer (early/late), liver cancer (early/late), and dementia.
Group 1 recognized ED as being a more serious disease than hypertension, diabetes mellitus (oral hypoglycemic agent), herpes zoster, chronic sinusitis, and chronic otitis media. In comparison, group 2 recognized ED as being a more serious condition than diabetes mellitus (insulin injection) and dementia (p<0.001 and p<0.001, respectively). In particular, ED was deemed to be more serious than hemodialysis, gastric cancer (early), lung cancer (early), and liver cancer (early) by men in group 2 in their 30s to 40s, and these results were statistically significant compared with the same age subgroups in group 1 (p<0.001, p<0.007, p<0.02, and p<0.007, respectively).
In contrast with their healthy counterparts, Korean men with ED recognized ED as being as serious as hemodialysis, dementia, and early stage cancer, which reflects the severe bother of ED in Korean patients.
Erectile dysfunction; Quality of life; Questionnaires
Computed tomography (CT), a standard diagnostic technique used to evaluate the extent of the sinus disease, fails to show bone involvement in patients with sinusitis. Bone scintigraphy is the gold standard procedure for detecting the bone involvement. Osteitis may be one of the reasons for discrepancies between extent of the disease as evaluated by CT and symptom scores. The aim of the study was to determine whether or not nuclear scintigraphy is useful in the diagnosis and management of acute, complicated acute and chronic sinusitis.
Forty patients with sinusitis were involved (9 acute, 4 complicated acute, 27 chronic sinusitis). 20 of the chronic sinusitis patients were with nasal polyps. All patients were evaluated with CT and SPECT (Single-photon emission tomography). 99Technetium-methylenediphosphate (99Tc-MDP) was administered for scintigraphic examination of the skull. Abnormal patterns of increased radionuclide uptake were identified and subjectively described. The mucosal involvement of sinusitis graded on Lund-Mackay Scale (LMS) was compared to degree of bone involvement evaluated by SPECT.
While, SPECT uptakes were negative (mean uptake index is less than about 2.5) in acute sinusitis, it's highly positive (mean uptake index is more than about 4) in complicated acute sinusitis. In group of chronic sinusitis, a positive correlation between the SPECT uptakes and LMS grade was found (P < 0.05).
In our view, the bone involvement as evaluated by SPECT correlates with the stage of chronic sinusitis. Poorer subjective response was observed in patients with positive SPECT. The clinical value of scintigraphy, is limited to special indications.