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1.  (E)-2-[4-(Trifluoro­meth­oxy)benzyl­idene]indan-1-one 
In the title compound, C17H11F3O2, the dihydro­indene ring is approximately planar with a maximum deviation of 0.024 (2) Å and makes a dihedral angle of 3.17 (8) Å with the adjacent benzene ring. In the crystal, mol­ecules are inter­connected by C—H⋯O inter­actions, forming an infinite chain along the c axis.
PMCID: PMC3213585  PMID: 22091162
2.  (E)-3-[4-(Dimethyl­amino)­benzyl­idene]-2,3-di­hydro-1H,9H-pyrrolo­[2,1-b]quinazolin-9-one 
The title compound, C20H19N3O, was obtained by condensation of 2,3-dihydro-1H,9H-pyrrolo­[2,1-b]quinazolin-9-one (alkaloid de­oxy­vasicinone, isolated from Peganum Harmala) with 4-(dimethyl­amino)­benzaldehyde in the presence of sodium methoxide. The 2,3-dihydro-1H,9H-pyrrolo­[2,1-b]quinazolin-9-one part of the mol­ecule is roughly planar (r.m.s. deviation = 0.0178 Å) and is essentially coplanar with the benzil­idene ring (r.m.s. deviation = 0.0080 Å), forming a dihedral angle of 5.0 (1)°. The crystal structure is stabilized by two aromatic π–π stacking inter­actions observed between the benzene rings of neighboring mol­ecules [centroid–centroid distance = 3.7555 (19) Å.
PMCID: PMC3006833  PMID: 21587830
3.  (E)-2-(4-Bromo­benzyl­idene)indan-1-one 
In the title compound, C16H11BrO, the dihydro­indene ring system is approximately planar, with a maximum deviation of 0.008 (2) Å. The mean plane of this ring system forms a dihedral angle of 3.73 (11)°, with the bromo-substituted benzene ring. In the crystal, weak inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into sheets parallel to the ab plane and further stabilization is provided by weak C—H⋯π inter­actions involving the bromo-substituted benzene rings.
PMCID: PMC3200602  PMID: 22058940
4.  (E)-2-(4-Chloro­benzyl­idene)indan-1-one 
In the title compound, C16H11ClO, the dihedral angle between the almost planar dihydro­indene ring system (r.m.s. deviation = 0.009 Å) and the chloro­benzene ring is 3.51 (14)°. In the crystal, mol­ecules are connected by C—H⋯O and weak C—H⋯Cl inter­actions, forming infinite layers parallel to (101).
PMCID: PMC3213510  PMID: 22091089
5.  (2E)-2-Benzyl­idene-5,6-dimethoxy­indan-1-one 
The mol­ecular structure of the title compound, C18H16O3, is roughly planar; the maximum deviation of the indanone ring system is 0.027 (1) Å and it makes a dihedral angle of 2.69 (3)° with the phenyl ring. The torsion angles between the two meth­oxy groups and the ­indanone ring are −14.67 (11) and −1.11 (12)°. In the crystal, mol­ecules are connected into a ribbon along the a axis via weak inter­molecular C—H⋯O hydrogen bonds. Weak inter­molecular C—H⋯π and π–π [centroid–centroid distance = 3.7086 (6) Å] inter­actions are also observed.
PMCID: PMC2983266  PMID: 21587524
6.  (E)-2-[4-(Piperidin-1-yl)benzyl­idene]-2,3-dihydro-1H-inden-1-one 
In the title compound, C21H21NO, the indene ring system is essentially planar with a maximum deviation of 0.066 (1) Å and makes dihedral angles of 7.93 (6) and 2.43 (6)°, respectively, with the benzene plane and the mean plane of the piperidine ring. These latter two planes make a dihedral angle of 7.61 (7)°. In the crystal, mol­ecules are linked by C—H⋯O inter­actions, forming infinite chains along the b axis.
PMCID: PMC3009073  PMID: 21589059
7.  N′-[4-(Dimethyl­amino)benzyl­idene]-3-hydr­oxy-2-naphthohydrazide 
The title compound, C20H19N3O2, was obtained by the condensation of 4-(dimethyl­amino)benzaldehyde with 3-hydr­oxy-2-naphthohydrazide. The mol­ecule is approximately planar, with an intra­molecular N—H⋯O hydrogen bond involving the imino H atom and the hydr­oxy O atom. The dihedral angle between the benzene ring and the naphthyl mean plane is 2.72 (13)°. In the crystal structure, symmetry-related mol­ecules are linked by inter­molecular O—H⋯O hydrogen bonds, forming chains propagating in the c-axis direction.
PMCID: PMC2969016  PMID: 21582600
8.  N′-[(Z)-4-(Dimethyl­amino)benzyl­idene]-4-nitro­benzohydrazide mono­hydrate 
In the asymmetric unit of the title compound, C16H16N4O3·H2O, there are two symmetry-independent hydrazide mol­ecules with almost identical geometries, and two independent water mol­ecules. The dihedral angles between the two benzene rings in the two hydrazide mol­ecules are 0.11 (5) and 0.77 (5)°. In one mol­ecule, an intra­molecular C—H⋯O hydrogen bond generates a ring of graph-set motif S(5). Inter­molecular N—H⋯O, O—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds and π–π stacking inter­actions between the benzene rings [centroid–centroid distances in the range 3.5021 (6)–3.6403 (6) Å] are observed, together with O⋯O [2.7226 (11) Å], O⋯N [2.7072 (10) Å] and N⋯O [2.7072 (10)–2.8582 (12) Å] short contacts. The hydrazine mol­ecules are stacked along the b axis and adjacent mol­ecules are linked by water mol­ecules.
PMCID: PMC2959418  PMID: 21201117
9.  N 2,N 2′-Bis[4-(dimethyl­amino)­benzyl­idene]pyridine-2,6-dicarbohydrazide monohydrate 
In the title compound, C25H27N7O2·H2O, the bis­[4-(dimethyl­amino)­benzyl­idene]pyridine-2,6-dicarbohydrazide mol­ecule and the water mol­ecule are located on a twofold rotation axis. The benzene and pyridine rings form a dihedral angle of 17.13 (7)°. In the crystal, inter­molecular N—H⋯O and O—H⋯O hydrogen bonds link the mol­ecules into a two-dimensional supermolecular structure parallel to the ab plane.
PMCID: PMC3009364  PMID: 21588930
10.  (E)-2-[4-(Trifluoro­meth­yl)benzyl­idene]-2,3-dihydro-1H-inden-1-one 
In the title mol­ecule, C17H11F3O, the indan ring system and the trifluoro­methyl-substituted benzene ring are approximately individually planar and form a dihedral angle of 1.81 (5)° with each other. In the crystal, mol­ecules are linked by pairs of weak bifurcated (C—H)2⋯O hydrogen bonds to form centrosymmetric dimers, generating R 2 1(6) and R 2 2(10) ring motifs. These dimers are connected by further weak C—H⋯O hydrogen bonds into one-dimensional chains along the b axis. Weak C—H⋯π inter­actions are also present.
PMCID: PMC3275283  PMID: 22347139
11.  N′-[(E)-Benzyl­idene]-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide 
In the title compound, C19H18N4O2, the 1,8-naphthyridine ring system is essentially planar [r.m.s. deviation = 0.011 (3) Å]. The dihedral angle between the naphthyridine ring system and the phenyl ring is 28.95 (7)°. The carbohydrazide H atom is involved in an intra­molecular N—H⋯O hydrogen bond, forming a six-membered hydrogen-bonded ring. In the crystal, the mol­ecules arrange themselves into centrosymmetric dimers by means of inter­molecular C—H⋯O hydrogen bonds.
PMCID: PMC2972033  PMID: 21578871
12.  N′-[4-(Dimethyl­amino)­benzyl­idene]furan-2-carbohydrazide 
The title compound, C14H15N3O2, was prepared by the reaction of 4-(dimethyl­amino)­benzaldehyde and furan-2-carbohydrazide. The dihedral angle between the benzene ring and the furan ring is 25.59 (19)°. In the crystal, mol­ecules are linked by inter­molecular N—H⋯O hydrogen bonds, forming chains along [010].
PMCID: PMC2983222  PMID: 21587664
13.  N′-[4-(Dimethyl­amino)benzyl­idene]-3-hydroxy­benzohydrazide 
The title compound, C16H17N3O2, was synthesized by the reaction of 4-dimethyl­amino­benzaldehyde with 3-hydroxy­benzoic acid hydrazide in methanol. The dihedral angle between the two benzene rings in the mol­ecule is 9.2 (2)°. In the crystal structure, mol­ecules are linked through inter­molecular O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds, forming layers parallel to the bc plane.
PMCID: PMC2960467  PMID: 21201497
14.  N′-[4-(Dimethyl­amino)­benzyl­idene]-4-meth­oxybenzohydrazide 
The title Schiff base compound, C17H19N3O2, was obtained from the condensation of 4-dimethyl­amino­benzaldehyde with 4-methoxy­benzohydrazide in an ethanol solution. The mol­ecule is twisted with respect to the N—N single bond [C—N—N—C = −159.27 (14)°] and the dihedral angle between the two aromatic rings is 67.1 (2)°. In the crystal structure, the mol­ecules are linked into chains along the c axis by inter­molecular N—H⋯O and C—H⋯O hydrogen bonds.
PMCID: PMC2959335  PMID: 21201227
15.  (E)-2-{2-tert-Butyl-6-[2-(4-hy­droxy­phen­yl)ethen­yl]-1-propyl-1,4-dihydro­pyridin-4-yl­idene}indane-1,3-dione 
The title compound, C29H29NO3, the nearly planar nine-membered indanedione ring [maximum deviation = 0.027 (2) Å] is located approximately parallel to its carrier pyridine ring [maximum deviation = 0.021 (2) Å] with a dihedral angle of 1.8 (1)° between the planes. However, because of steric hindrance, the benzene ring [maximum deviation = 0.006 (2) Å] is not parallel to the pyridine ring [dihedral angle = 37.29 (8)°]. The mol­ecules display numerous inter­molecular π–π inter­actions between the five- and six-membered rings, the shortest centroid–centroid distance being 3.796 (2) Å. There are inter- and intra­molecular O—H⋯O and C—H⋯O hydrogen bonds.
PMCID: PMC3050276  PMID: 21522650
16.  4-{[4-(Di­methyl­amino)­benzyl­idene]amino}­benzene­sulfonamide 
The title Schiff base compound, C15H17N3O2S, is non-planar with a dihedral angle of 69.88 (4)° between the planes of the benzene rings. In the crystal, pairs of N—H⋯N hydrogen bonds, between the sulfonamide nitro­gen-H atom and the azomethine N atom, link the mol­ecules into inversion dimers, forming R 2 2(16) ring motifs. These dimers are linked by N—H⋯O hydrogen bonds, between the sulfonamide nitro­gen-H atom and one sulfonamide O atom, forming sheets lying parallel to (100). Within the sheets there are weak parallel slipped π–π inter­actions involving inversion-related benzene­sulfonamide rings [centroid–centroid distance = 3.8800 (9) Å; normal distance = 3.4796 (6) Å; slippage = 1.717 Å].
PMCID: PMC4051049  PMID: 24940295
17.  (E)-N′-[4-(Dimethyl­amino)­benzyl­idene]-4-hy­droxy­benzohydrazide hemihydrate 
In the title compound, C16H17N3O2·0.5H2O, the two hydrazide mol­ecules are approximately planar: the dihedral angles between the two substituted benzene rings are 7.7 (2) and 4.2 (2)°. Both hydrazone mol­ecules exist in a trans geometry with respect to their methyl­idene units. In the crystal, the water mol­ecule lies between the two organic mol­ecules and makes bifurcated O—H⋯(N,O) hydrogen bonds to both of them. The hydrazide mol­ecules form N—H⋯O and O—H⋯O hydrogen bonds, resulting in a three-dimensional network.
PMCID: PMC3006866  PMID: 21587822
18.  2-{[4-(Dimethyl­amino)­benzyl­idene]amino}­phenyl disulfide 
In the title mol­ecule, C30H30N4S2, the two benzene rings connected through the disulfide chain form a dihedral angle of 88.7 (1)°, and the two benzene rings in the benzyl­ideneaniline fragments form dihedral angles of 34.0 (1) and 35.4 (1)°. The crystal packing exhibits no significantly short inter­molecular contacts.
PMCID: PMC3238898  PMID: 22199751
19.  4-Bromo-2-(4-fluoro­benzyl­idene)indan-1-one 
In the mol­ecule of the title compound, C16H10BrFO, the indane ring system is planar with a maximum deviation of 0.020 (3) Å. An intra­molecular C—H⋯O inter­action results in the formation of a planar ring, which is oriented at dihedral angles of 2.24 (3) and 2.34 (3)° with respect to the adjacent rings. π–π contacts between the benzene and indane rings [centroid–centroid distances = 3.699 (1) and 3.786 (1)Å] may stabilize the crystal structure.
PMCID: PMC2977330  PMID: 21583618
20.  4-Chloro-N′-[(Z)-4-(dimethyl­amino)benzyl­idene]benzohydrazide mono­hydrate 
In the title compound, C16H16ClN3O·H2O, the dihedral angle between the two aromatic rings is 44.58 (11)°. The N atom of the dimethyl­amino group adopts a pyramidal configuration. In the crystal structure, mol­ecules are linked into a two-dimensional network parallel to the (001) plane by inter­molecular N—H⋯O, O—H⋯N and O—H⋯O hydrogen bonds involving the water mol­ecule and C—H⋯Cl hydrogen bonds. In addition, C—H⋯π inter­actions are observed.
PMCID: PMC2962208  PMID: 21203289
21.  N,N′-Bis[2-chloro-5-(trifluoro­meth­yl)benzyl­idene]ethane-1,2-diamine 
The mol­ecule of the title Schiff base compound, C18H12Cl2F6N2, adopts an E configuration with respect to the azomethine C=N bond. Intra­molecular C—H⋯F (× 2) and C—H⋯Cl (× 2) hydrogen bonds generate S(5) ring motifs. The imino group is coplanar with the aromatic ring. Within the mol­ecule, the planar units are parallel, but extend in opposite directions from the methyl­ene bridge, as indicated by the dihedral angle between the two benzene rings of 3.74 (6)°. The inter­esting features of the crystal structure are weak inter­molecular Cl⋯N and F⋯F inter­actions, with distances of 2.9192 (11) and 3.2714 (10) Å, respectively, which are shorter than the sum of the van der Waals radii of the relevent atoms. These inter­actions link neighbouring mol­ecules into dimers which are stacked down the b axis.
PMCID: PMC2960650  PMID: 21201706
22.  (E)-1-[4-(Dimethyl­amino)benzyl­idene]thio­semicarbazide 
In the title mol­ecule, C10H14N4S, the thio­rea plane and benzene ring form a dihedral angle of 16.0 (3) Å. In the crystal structure, inter­molecular N—H⋯S hydrogen bonds link the mol­ecules into ribbons extended in the [100] direction; these incorporate inversion dimers.
PMCID: PMC2968255  PMID: 21581854
23.  (E)-4-Chloro-2-{[4-(di­methyl­amino)­benzyl­idene]amino}­phenol 
In the title aromatic Schiff base compound, C15H15ClN2O, the mol­ecule exists in a trans conformation with respect to the C=N bond. The dihedral angle between the benzene rings is 14.49 (6)°. In the crystal, weak C—H⋯π inter­actions link mol­ecules into supra­molecular chains propagated along the a-axis direction.
PMCID: PMC4011262  PMID: 24860397
24.  N′-[4-(Dimethyl­amino)benzyl­idene]benzohydrazide 
In the title mol­ecule, C16H17N3O, the two aromatic rings form a dihedral angle of 4.51 (18)°. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds link mol­ecules related by translation along the a axis into ribbons.
PMCID: PMC2970421  PMID: 21577924
25.  (E)-N′-[4-(Dimethyl­amino)­benzyl­idene]-2-meth­oxy­benzohydrazide 
In the title compound, C17H19N3O2, the two benzene rings form a dihedral angle of 89.2 (2)°. In the crystal structure, mol­ecules are linked through N—H⋯O hydrogen bonds, forming C(4) chains running along the c axis.
PMCID: PMC3006873  PMID: 21587988

Results 1-25 (383676)