In the title compound, C28H24F6N2O3, the mean plane of the central pyrazoline ring forms dihedral angles of 2.08 (9) and 69.02 (16)° with the 2-benzyloxy-6-hydroxy-4-methylphenyl and 3,5-bis(trifluoromethyl)phenyl rings, respectively. The dihedral angle between the mean planes of the pyrazoline and 3,5-bis(trifluoromethyl)phenyl rings is 68.97 (9)°. An intramolecular O—H⋯N hydrogen bond is observed, which forms an S(6) graph-set motif. In the crystal, pairs of weak C—H⋯F halogen interactions link the molecules into inversion dimers while molecular chains along  are formed by C—H⋯O contacts.
In the title compound, C21H24O3, the conformation of the enone group is s–cis. The benzene rings are inclined at an angle of 7.9 (1)°. The alkoxy tail is planar, with a maximum deviation from the least-squares plane of 0.009 (2) Å, and adopts a trans conformation throughout. An intramolecular O—H⋯O interaction between the keto and hydroxy groups forms S(6) ring motifs. In the crystal, molecules are arranged in a head-to-tail manner down the a axis and are subsequently stacked along the b axis, forming molecular sheets parallel to the ab plane. The crystal structure is further stabilized by weak C—H⋯π interactions and short C⋯O [3.376 (2) Å] contacts.
In the title molecule, C16H13Cl2FN2OS, the dihedral angle between the thiophene and benzene rings is 80.34 (12)°. The pyrazoline ring is in an envelope conformation, and the plane through the four coplanar atoms makes dihedral angles of 85.13 (9) and 6.89 (10)° with the thiophene and benzene rings, respectively. The C and O atoms of the acetyl group are nearly coplanar with the attached pyrazoline ring. In the crystal structure, inversion dimers arise from pairs of intermolecular C—H⋯O hydrogen bonds. A short intermolecular Cl⋯S contact of 3.4250 (13) Å is also found.
In the title compound, C17H15ClN2O2, the benzene rings form dihedral angles of 89.56 (5) and 5.87 (5)° with the mean plane of the pyrazoline ring (r.m.s. deviation = 0.084 Å). The dihedral angle between the two benzene rings is 87.57 (5)°. In the crystal, molecules are linked by O—H⋯O and C—H⋯O hydrogen bonds into a helical chain along the c axis. Between the chains weak C—H⋯N and C—H⋯O interactions are present. The crystal studied was an inversion twin with a domain ratio of 0.72 (4):0.28 (4).
In the title molecule, C17H14BrFN2O, the benzene rings form dihedral angles of 6.58 (6) and 85.31 (6)° with the mean plane of the 4,5-dihydro-1H-pyrazole ring (r.m.s. deviation = 0.0231 Å). The latter ring is planar with a maximum deviation of 0.032 (1) Å The dihedral angle between the benzene rings is 78.75 (6)°. In the crystal, weak C—H⋯O and C—H⋯F hydrogen bonds link the molecules into corrugated layers parallel to the ab plane.
In the title compound, C21H24O3, the enone moiety adopts an s-cis conformation and the dihedral angle between the benzene rings is 12.89 (6)°. The hexyloxy tail adopts an extended conformation. In the crystal, inversion dimers are linked by pairs of O—H⋯O hydrogen bonds and pairs of C—H⋯O interactions, forming two R
2(7) and one R
2(10) loops. The dimers are then arranged into sheets lying parallel to (201) and weak C—H⋯π interactions consolidate the packing.
There are two molecules in the asymmetric unit of the title compound, C21H24O3, in which the dihedral angles between the aromatic rings are 6.4 (1) and 7.0 (1)°. The enone moiety of both molecules adopts an s–cis configuration. In the crystal, intermolecular O—H⋯O and C—H⋯O interactions to the same acceptor O atom generate R
1(6) ring motifs and further C—H⋯O interactions generate R
2(8) ring motifs. Topologically, the R
1(6) and R
2(8) ring motifs are arranged alternately, forming  chains of molecules. The crystal structure is further stabilized by C—H⋯π interactions.
In the title compound, C25H20N2O, the pyrazoline ring is nearly planar [maximum atomic deviation = 0.0254 (17) Å]; but the anthracene ring system is distorted from a coplanar structure [maximum atomic deviation = 0.181 (3) Å], the dihedral angle between the outer benzene rings being 10.68 (13)°. The pyrazoline ring is almost perpendicular to the mean plane of the anthracene ring system [dihedral angle = 76.94 (8)°], but nearly coplanar with the phenyl ring [dihedral angle = 1.63 (7)°]. π–π stacking is observed between parallel benzene rings of adjacent anthracene units, the face-to-face distance being 3.27 (3) Å. Weak intramolecular C—H⋯N hydrogen bonding also occurs.
In the molecule of title pyrazoline derivative, C17H18N4OS, the pyrazole ring adopts an envelope conformation with the flap atom, which bears the methoxyphenyl substituent, displaced by 0.0750 (12) Å from the plane through the other ring atoms. The two substituted benzene rings make a dihedral angle of 70.59 (6)°. The methoxy group is twisted slightly with respect to the attached benzene ring [Cmethyl—O—C—C torsion angle = −8.84 (15)°]. An intramolecular N—H⋯N hydrogen bond occurs. In the crystal, the pyrazoline molecules are linked by N—H⋯O and N—H⋯S hydrogen bonds into zigzag layers parallel to the bc plane and stacked along the a axis by π–π interactions with centroid–centroid distances of 3.4690 (7) and 3.5792 (7) Å. C—H⋯π interactions are also present.
In the title compound, C17H15FN2O, the pyrazoline ring adopts a flattened envelope conformation. The dihedral angle between the fluoro-substituted benzene ring and the phenyl ring is 69.20 (5)°. In the crystal, a pair of C—H⋯O hydrogen bonds link neighbouring molecules, forming an inversion dimer. The crystal structure is further consolidated by C—H⋯π interactions and by a π–π interaction with a centroid–centroid distance of 3.7379 (6) Å.
The title molecule, C18H18N2O2, is V-shaped with the pyrazoline moiety being inclined to the adjacent phenyl ring by an angle of 6.49 (9)°, while the 4-methoxy-substituted ring is inclined to the pyrazoline ring by 82.99 (9)°. In the crystal, adjacent molecules are linked by C—H⋯O interactions, forming chains propagating in . There are also C—H⋯π interactions involving adjacent molecules and those related by an inversion center.
In the title compound, C24H19N3O, the pyrazoline ring adopts an envelope conformation with the C atom linking to the pyridine ring as the flap. The mean plane of the pyrazoline ring makes dihedral angles of 85.54 (4) and 81.66 (3)° with the pyridine ring and the anthracene ring system, respectively. In the crystal, molecules are linked by C—H⋯O hydrogen bonds. In addition, weak π–π interactions [centroid–centroid distances = 3.695 (3)–3.850 (7) Å] are observed.
The asymmetric unit of the title compound, C18H18ClN3OS·C2H5OH, comprises a pyrazoline derivative and an ethanol solvent molecule. In the molecule of the pyrazoline derivative, the pyrazole ring adopts an envelope conformation with the C atom bearing the ethoxyphenyl substituent as the flap. The dihedral angle between the benzene rings is 74.22 (7)°. The ethoxy group is coplanar with the attached benzene ring [C—O—C—Cmethyl = 175.50 (11)° and r.m.s. deviation = 0.0459 (1) Å for the nine non-H atoms]. In the crystal, the pyrazoline molecules are linked by N—H⋯Oethoxy hydrogen bonds into chains along the c axis and are further linked with the solvent ethanol molecules by N—H⋯Oethanol and Oethanol—H⋯S hydrogen bonds. C—H⋯π interactions are also present.
In the title compound, C21H24O3, the enone group adopts an s–cis conformation. The planes of the aromatic rings are inclined at an angle of 6.1 (1)°. The alkoxy tail is not linear, with the maximum deviation from the least-squares plane being 0.375 (2) Å. Molecules are connected into extended chains along the a axis through O—H⋯Ocarbonyl hydrogen bonds and are interlinked via C—H⋯O interactions to form a two-dimensional array parallel to the ab plane.
In the title compound, C29H27Cl2N5O2·C4H8O, the polycyclic system is composed of three parts: one central pyridine ring substituted by two functionalized pyrazoline rings. The dihedral angles between the central pyridine plane and pyrazoline planes are 5.11 (1) and 13.99 (1)°, whereas the dihedral angles between each chlorophenyl plane and the attached pyrazoline planes are 88.65 (1) and 83.87 (1)°. Molecules are linked by intermolecular C—H⋯O hydrogen bonds, forming a three-dimensional network.
In the title compound, C23H25ClF2N3O2
−, the triazole ring makes dihedral angles of 60.9 (4) and 25.0 (3)° with the 6-chlorophenyl and 2,4-difluorophenyl rings, respectively. The molecule adopts a Z configuration about the C=C double bond. In the crystal, the cations and anions are linked by N—H⋯O hydrogen bonds and weak C—H⋯O interactions.
In the title compound, C17H18N4OS, a pyrazoline derivative, the pyrazoline ring adopts an envelope conformation with the C atom bonded to the benzene ring as the flap atom. The dihedral angle between the pyridine and benzene rings is 80.50 (6)°. The ethoxyphenyl group is approximately planar, with an r.m.s. deviation of 0.0238 (1) Å for the nine non-H atoms. In the crystal, molecules are linked by N—H⋯O and N—H⋯S hydrogen bonds into a tape along the b axis. Weak C—H⋯N and C—H⋯π interactions are also observed.
The title compound, C17H15N3O3, was prepared from 1-(2-nitrophenyl)-3-phenylprop-2-en-1-one and hydrazine. The dihedral angle between the benzene and phenyl rings is 74.55 (2)°. The pyrazoline ring is in a slight envelope conformation with the C atom bonded to the phenyl ring forming the flap. In the crystal structure, weak intermolecular C—H⋯O hydrogen bonds connect molecules into chains along .
The title compound, C29H27Cl2N5O2, contains a central pyridine ring and two functionalized pyrazoline rings. The pyridine ring and the two attached pyrazoline rings are nearly coplanar, whereas the terminal chlorophenyl rings are nearly perpendicular to the attached pyrazoline rings [dihedral angles = 86.78 (1) and 77.70 (1)°]. Molecules are linked by weak intermolecular C—H⋯O hydrogen bonding.
The title compound, C12H13ClN2O2, crystallizes with two independent but very similar molecules (A and B) in the asymmetric unit. The pyrazole ring in each molecule has an envelope conformation. The dihedral angle between the pyrazole ring mean plane and the benzene ring is 86.07 (14)° in A and 85.99 (14)° in B. In the crystal, the A and B molecules are linked via a pair of O—H⋯O hydrogen bonds, forming dimers. These dimers are further linked via C—H⋯O interactions to form –A–B–A–B– chains propagating along the c-axis direction.
In the molecule of the title compound, C16H15NO5, the aromatic rings are oriented at a dihedral angle of 74.89 (3)°. Intramolecular C—H⋯O interactions result in the formation of a seven-membered ring. In the crystal structure, weak intermolecular C—H⋯O interactions link the molecules into chains along the b axis.
In the title compound, C24H24N2O4, the pendant benzene and naphthalene ring systems make dihedral angles of 87.9 (3) and 19.2 (3)°, respectively, with the central pyrazoline ring. In the crystal structure, weak C—H⋯O interactions help to establish the packing.
The title compound, C15H12F2O3, has been obtained by the reaction of 2,4-dihydroxylacetonephenone, potassium carbonate and 3,5-difluorobenzyl bromide. The hydroxy group is involved in an intramolecular O—H⋯O hydrogen bond in each of the two independent molecules in the asymmetric unit. The dihedral angle between the aromatic rings is 0.5 (2)° in one molecule and 1.9 (2)° in the other. In the crystal, weak C—H⋯O interactions link the molecules into tetrameric units aligned perpendicular to b.
In the asymmetric unit of the title compound, C17H14F2N2O, there are three independent molecules (A, B and C) which differ slightly in the relative orientations of the two fluorophenyl rings. In molecules A and C one of the fluorophenyl rings is disordered over two positions, with occupancy ratios of 0.72 (2):0.28 (2) for molecule A and 0.67 (2):0.33 (2) for molecule C. The dihedral angle between the two fluorophenyl rings in the independent molecules lie in the range 70.3 (3)–84.0 (3)°. In the crystal structure, the molecules are linked via intermolecular C—H⋯O and C—H⋯F hydrogen bonds and π⋯π stacking interactions [centroid–centroid distance = 3.7508 (13) Å], forming a three-dimensional network.
In the title ester derivative, C28H29NO6·0.5H2O, the 1,4-dihydropyridine ring has a flattened boat conformation. The mean plane is almost perpendicular to the attached benzene ring, making a dihedral angle of 86.87 (9)°. The terminal phenyl ring is inclined to the central benzene ring by 67.56 (12)°. In the crystal, molecules are bridged via O—H⋯O hydrogen bonds involving the partially occupied water molecule, and this arrangement is strengthened by a pair of N—H⋯O hydrogen bonds and C—H⋯O interactions. The ethyl atoms of one of the ethyl ester groups are disordered over two sites with an occupancy ratio of 0.716 (5):0.284 (5).