Search tips
Search criteria

Results 1-25 (243539)

Clipboard (0)

Related Articles

5.  Thomas Dover's life and legacy 
Medical History  1976;20(1):88.
PMCID: PMC1081702
6.  Thomas Dover and the South Sea Company. 
Medical History  1974;18(2):107-121.
PMCID: PMC1081536  PMID: 4607289
British Medical Journal  1957;2(5057):1354.
PMCID: PMC1963033
8.  Further Notes on Thomas Dover 
Proceedings of the Royal Society of Medicine  1913;6(Sect Hist Med):233-237.
PMCID: PMC2006240  PMID: 19977248
10.  Doctor's Adventures 
British Medical Journal  1962;2(5299):242.
PMCID: PMC1925672
12.  A children’s asthma education program: Roaring Adventures of Puff (RAP), improves quality of life 
It is postulated that children with asthma who receive an interactive, comprehensive education program would improve their quality of life, asthma management and asthma control compared with children receiving usual care.
To assess the feasibility and impact of ‘Roaring Adventures of Puff’ (RAP), a six-week childhood asthma education program administered by health professionals in schools.
Thirty-four schools from three health regions in Alberta were randomly assigned to receive either the RAP asthma program (intervention group) or usual care (control group). Baseline measurements from parent and child were taken before the intervention, and at six and 12 months.
The intervention group had more smoke exposure at baseline. Participants lost to follow-up had more asthma symptoms. Improvements were significantly greater in the RAP intervention group from baseline to six months than in the control group in terms of parent’s perceived understanding and ability to cope with and control asthma, and overall quality of life (P<0.05). On follow-up, doctor visits were reduced in the control group.
A multilevel, comprehensive, school-based asthma program is feasible, and modestly improved asthma management and quality of life outcomes. An interactive group education program offered to children with asthma at their school has merit as a practical, cost-effective, peer-supportive approach to improve health outcomes.
PMCID: PMC2866218  PMID: 20422062
Asthma education; Childhood asthma; Program evaluation; Quality of life; School-based program
13.  The Adventures of Dr. Duncan McNab McEachran in Western Canada 
The Canadian Veterinary Journal  1979;20(6):149-156.
Duncan McNab McEachran's early history and involvement in the formation of the Montreal Veterinary College as well as in livestock inspection were reviewed. His contribution to the beginning of the ranching industry in western Canada was explored in detail. In 1881, McEachran helped to establish the Cochrane Ranche, which was the first great ranch to be started in southern Alberta. He was employed as the ranch's resident general manager until 1883, in which year the Waldrond Ranch was established. McEachran was this ranch's president and general manager until approximately 1909. During this time, he came under considerable criticism from both The MacLeod Gazette and The Calgary Herald. As Dr. McEachran maintained his obligations to the ranches while he was directing the veterinary college in Montreal as well as chief inspector of livestock for Canada, it was concluded that this feat alone would rank him as a remarkable historical figure.
PMCID: PMC1789563  PMID: 380798
14.  Adventures in vascular biology: a tale of two mediators 
I would like to thank the Royal Society for inviting me to deliver the Croonian Lecture. In so doing, the Society is adding my name to a list of very distinguished scientists who, since 1738, have preceded me in this task. This is, indeed, a great honour.
For most of my research career my main interest has been the understanding of the normal functioning of the blood vessel wall and the way this is affected in pathology. During this time, our knowledge of these subjects has grown to such an extent that many people now believe that the conquering of vascular disease is a real possibility in the foreseeable future.
My lecture concerns the discovery of two substances, prostacyclin and nitric oxide. I would like to describe the moments of insight and some of the critical experiments that contributed significantly to the uncovering of their roles in vascular biology. The process was often adventurous, hence the title of this lecture. It is the excitement of the adventure that I would like to convey in the text that follows.
PMCID: PMC1609404  PMID: 16627292
prostacyclin; aspirin; nitric oxide; oxidative stress; free radicals; cardiovascular pathology
15.  Adventures in public data 
This article contains the slides and transcript of a talk given by Dan Zaharevitz at the "Visions of a Semantic Molecular Future" symposium held at the University of Cambridge Department of Chemistry on 2011-01-19. A recording of the talk is available on the University Computing Service's Streaming Media Service archive at (unfortunately the first part of the recording was corrupted, so the talk appears to begin at slide 6, 'At a critical time'). We believe that Dan's message comes over extremely well in the textual transcript and that it would be poorer for serious editing. In addition we have added some explanations and references of some of the concepts in the slides and text. (Charlotte Bolton; Peter Murray-Rust, University of Cambridge)
Editorial preface
The following paper is part of a series of publications which arose from a Symposium held at the Unilever Centre for Molecular Informatics at the University of Cambridge to celebrate the lifetime achievements of Peter Murray-Rust. One of the motives of Peter's work was and is a better transport and preservation of data and information in scientific publications. In both respects the following publication is relevant: it is about public data and their representation, and the publication represents a non-standard experiment of transporting the content of the scientific presentation. As you will see, it consists of the original slides used by Dan Zaharevitz in his talk "Adventures in Public Data" at the Unilever Centre together with a diligent transcript of his speech. The transcribers have gone through great effort to preserve the original spirit of the talk by preserving colloquial language as it is used at such occasions. For reasons known to us, the original speaker was unable to submit the manuscript in a more conventional form. We, the Editors, have discussed in depth whether such a format is suitable for a scientific journal. We have eventually decided to publish this "as is". We did this mostly because it was Peter's wish that this talk was published in this form and because we agreed with his notion that this format transmits the message just as well as a formal article as defined by our instructions for authors. We, the Editors, wish to make clear however that this is an exception that we made because we would like to preserve the temporal unity and message of this set of publications. Insisting on a formal publication would have meant losing this historical account as part of the thematic series of papers or disrupting the series. We hope that this will find the consent of our readership.
PMCID: PMC3198951  PMID: 22017861
16.  Adventures with Cyanobacteria: A Personal Perspective 
Cyanobacteria, or the blue-green algae as they used to be called until 1974, are the oldest oxygenic photosynthesizers. We summarize here adventures with them since the early 1960s. This includes studies on light absorption by cyanobacteria, excitation energy transfer at room temperature down to liquid helium temperature, fluorescence (kinetics as well as spectra) and its relationship to photosynthesis, and afterglow (or thermoluminescence) from them. Further, we summarize experiments on their two-light reaction – two-pigment system, as well as the unique role of bicarbonate (hydrogen carbonate) on the electron-acceptor side of their photosystem II, PSII. This review, in addition, includes a discussion on the regulation of changes in phycobilins (mostly in PSII) and chlorophyll a (Chl a; mostly in photosystem I, PSI) under oscillating light, on the relationship of the slow fluorescence increase (the so-called S to M rise, especially in the presence of diuron) in minute time scale with the so-called state-changes, and on the possibility of limited oxygen evolution in mixotrophic PSI (minus) mutants, up to 30 min, in the presence of glucose. We end this review with a brief discussion on the position of cyanobacteria in the evolution of photosynthetic systems.
PMCID: PMC3355777  PMID: 22645530
Anacystis nidulans (Synechococcus elongatus – strain PCC 7942); Synechocystis sp. PCC 6803; P750; chlorophyll a fluorescence; red drop; Emerson enhancement effect; photosystem II; photosystem I
17.  Adventures in data citation: sorghum genome data exemplifies the new gold standard 
BMC Research Notes  2012;5:223.
Scientific progress is driven by the availability of information, which makes it essential that data be broadly, easily and rapidly accessible to researchers in every field. In addition to being good scientific practice, provision of supporting data in a convenient way increases experimental transparency and improves research efficiency by reducing unnecessary duplication of experiments. There are, however, serious constraints that limit extensive data dissemination. One such constraint is that, despite providing a major foundation of data to the advantage of entire community, data producers rarely receive the credit they deserve for the substantial amount of time and effort they spend creating these resources. In this regard, a formal system that provides recognition for data producers would serve to incentivize them to share more of their data.
The process of data citation, in which the data themselves are cited and referenced in journal articles as persistently identifiable bibliographic entities, is a potential way to properly acknowledge data output. The recent publication of several sorghum genomes in Genome Biology is a notable first example of good data citation practice in the field of genomics and demonstrates the practicalities and formatting required for doing so. It also illustrates how effective use of persistent identifiers can augment the submission of data to the current standard scientific repositories.
PMCID: PMC3392744  PMID: 22571506
18.  Mercury. A history of quicksilver 
Medical History  1977;21(4):461.
PMCID: PMC1082118
19.  Quick fixes for quicksilver. 
Environmental Health Perspectives  1998;106(2):A74-A76.
Mercury pollution is a persistent and increasing problem in the environment. Along with some natural sources of the metal, major man-made sources of mercury pollution include incinerators, fossil fuel plants, and municipal sewage systems. The EPA estimated that in 1989, approximately 643,000 kg of mercury was discarded as municipal solid waste, with 84% of it landfilled.
PMCID: PMC1533006  PMID: 9456343
21.  QuickSilver Clinical Tracker – a Risk-Management Approach 
While many guidelines strive to automate the high-granular clinical thought process, the resulting risk stratification is often a lowgranular management class (i.e. low, medium or high risk). Furthermore, the “low hanging fruit” of guidelines is not in decision support, rather in the subsequent action tracking. Therefore, we believe that only a small amount of data is required to produce significant reminders. In our approach, the clinician risk-stratifies the patient and enters the guideline at the management level. We do not attempt to replicate the clinical thought process; rather we ask the question, “Now that you have decided, how can we help track your decisions?” A risk-management approach encapsulates salient guideline features and provides a framework for basic decision support and data tracking.
PMCID: PMC1479974  PMID: 14728492
22.  Quicksilver & Gold: Mercury Pollution from Artisanal and Small-Scale Gold Mining 
Environmental Health Perspectives  2012;120(11):a424-a429.
PMCID: PMC3556620  PMID: 23117138
25.  Dover Meeting 
PMCID: PMC2558601

Results 1-25 (243539)