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1.  Apolipoprotein C-I Levels Are Associated with the Urinary Protein/Urinary Creatinine Ratio in Pediatric Idiopathic Steroid-Sensitive Nephrotic Syndrome: A Case Control Study 
Humoral factors may cause idiopathic steroid-sensitive nephrotic syndrome (ISSNS). In the present study, we analyzed serum proteins using mass spectrometry (MS) to identify proteins associated with the pathophysiology of pediatric ISSNS. We collected serial serum samples from 33 children during each ISSNS phase; Phase A1 is the acute phase prior to steroid treatment (STx), Phase A2 represents the remission period with STx, and Phase A3 represents the remission period after completion of STx. Children with normal urinalyses (Group B) and children with a nephrotic syndrome other than ISSNS (Group C) served as controls. No significant differences in urinary protein/urinary creatinine (UP/UCr) ratios were observed between the children with phase A1 ISSNS and Group C. We used surface-enhanced laser desorption/ionization time of flight MS for sample analysis. Four ion peaks with a mass-to-charge ratio (m/z) of 6,444, 6,626, 8,695, and 8,915 were significantly elevated during ISSNS Phase A1 compared to Phase A2, Phase A3, and Group C. The intensity of an m/z of 6,626 significantly correlated with the UP/UCr ratio and an m/z of 6,626 was identified as apolipoprotein C-I (Apo C-I). Apo C-I levels correlate with the UP/UCr ratio in pediatric ISSNS. Our findings provide new insights into the pathophysiology of ISSNS.
PMCID: PMC5303865
2.  ISSN Roundtable: FAQs About the ISSN 
Mission Statement of the ISSN
The mission of the International Society of Sports Nutrition is to be recognized as the leading professional organization in the study and application of sports nutrition. The ISSN is dedicated to promoting and supporting the study, practice, education, research and development of sports nutrition and the sports nutrition profession. All information disseminated by the ISSN is unbiased and scientifically supported.
PMCID: PMC2129135  PMID: 18500952
3.  Automated Analysis of Fundamental Features of Brain Structures 
Neuroinformatics  2011;9(4):371-380.
Automated image analysis of the brain should include measures of fundamental structural features such as size and shape. We used principal axes (P-A) measurements to measure overall size and shape of brain structures segmented from MR brain images. The rationale was that quantitative volumetric studies of brain structures would benefit from shape standardization as had been shown for whole brain studies. P-A analysis software was extended to include controls for variability in position and orientation to support individual structure spatial normalization (ISSN). The rationale was that ISSN would provide a bias-free means to remove elementary sources of a structure’s spatial variability in preparation for more detailed analyses. We studied nine brain structures (whole brain, cerebral hemispheres, cerebellum, brainstem, caudate, putamen, hippocampus, inferior frontal gyrus, and precuneus) from the 40-brain LPBA40 atlas. This paper provides the first report of anatomical positions and principal axes orientations within a standard reference frame, in addition to “shape/size related” principal axes measures, for the nine brain structures from the LPBA40 atlas. Analysis showed that overall size (mean volume) for internal brain structures was preserved using shape standardization while variance was reduced by more than 50%. Shape standardization provides increased statistical power for between-group volumetric studies of brain structures compared to volumetric studies that control only for whole brain size. To test ISSN’s ability to control for spatial variability of brain structures we evaluated the overlap of 40 regions of interest (ROIs) in a standard reference frame for the nine different brain structures before and after processing. Standardizations of orientation or shape were ineffective when not combined with position standardization. The greatest reduction in spatial variability was seen for combined standardizations of position, orientation and shape. These results show that ISSNs automated processing can be a valuable asset for measuring and controlling variability of fundamental features of brain structures.
PMCID: PMC3738178  PMID: 21360205
ISSN; Spatial incidence map; Volumetric variance; Mango; Principal axis analysis; Shape standardization; LPBA40
4.  ISSN exercise & sport nutrition review: research & recommendations 
Sports nutrition is a constantly evolving field with hundreds of research papers published annually. For this reason, keeping up to date with the literature is often difficult. This paper is a five year update of the sports nutrition review article published as the lead paper to launch the JISSN in 2004 and presents a well-referenced overview of the current state of the science related to how to optimize training and athletic performance through nutrition. More specifically, this paper provides an overview of: 1.) The definitional category of ergogenic aids and dietary supplements; 2.) How dietary supplements are legally regulated; 3.) How to evaluate the scientific merit of nutritional supplements; 4.) General nutritional strategies to optimize performance and enhance recovery; and, 5.) An overview of our current understanding of the ergogenic value of nutrition and dietary supplementation in regards to weight gain, weight loss, and performance enhancement. Our hope is that ISSN members and individuals interested in sports nutrition find this review useful in their daily practice and consultation with their clients.
PMCID: PMC2853497  PMID: 20181066
5.  ISSN Exercise & Sport Nutrition Review: Research & Recommendations 
Sport nutrition is a constantly evolving field with literally thousands of research papers published annually. For this reason, keeping up to date with the literature is often difficult. This paper presents a well-referenced overview of the current state of the science related to how to optimize training through nutrition. More specifically, this article discusses: 1.) how to evaluate the scientific merit of nutritional supplements; 2.) general nutritional strategies to optimize performance and enhance recovery; and, 3.) our current understanding of the available science behind weight gain, weight loss, and performance enhancement supplements. Our hope is that ISSN members find this review useful in their daily practice and consultation with their clients.
PMCID: PMC2129137
sport nutrition; dietary supplements; ergogenic aids; weight gain; weight loss
7.  Abstracts from ISSN Brazil 
Heibel, André Barroso | Perim, Pedro Henrique Lopes | Saunders, Bryan | Heibel, André Barroso | Abrantes, Déborah Michelly | Rauber, Caíque Fagundes | Reis, Caio Eduardo Gonçalves | Santana, Jeferson Oliveira | Madureira, Diana | de França, Elias | Yoshioka, Caroline Ayme Fernandes | Lamolha, Marco Aurélio | Zocoler, Cesar Augustus | e Silva, Paulo Roberto Sousa | Caperuto, Erico Chagas | Goston, Janaína Lavalli | dos Santos, Bárbara Ferreira | daSilva, Francine Rafaela Fernandes | de Carvalho, Lívia Muniz Cirino | Ramos, Sabrina Alves | Madureira, Diana | Santana, Jeferson O. | de França, Elias | Gonçalves, Leandro | Santos, Ronaldo V. T. | Sanches, Iris Callado | Ramos, Carla C. | Caperuto, e Érico Chagas | Romeiro, Caroline | Pires, Gabrielle Goncalves | Correia, Vitória C. A. R. A. | Macedo, Maria Cecilia F. | Franco, Octavio L. | Martins, Breno | Marangon, Antonio Felipe Correa | Paulista, Hugo | Norte, Pablo Almeida Macedo | Da Fonseca, Danielle Almeida | De Souza, Debora Teixeira | Alves, Ana Gabriella Pereira | Franco, Lana Pacheco | Silva, Maria Sebastiana | Perim, Pedro Henrique Lopes | Heibel, André Barroso | Gualano, Bruno | Saunders, Bryan | de França, Elias | Madureira, Diana | Bella, Yanesko | Lira, Fabio Santos | Santana, Jeferson O. | Fukushima, Andre | Burton, Alex | Caperuto, Erico Chagas | de Azevedo, Artur P. | Fogaça, Lorruama J. | Santos, Silvia L. | Mota, João F. | Pimentel, Gustavo D. | Figueiredo, Nayra | Queiroz, Marcela | Santos, Jéssica | Mota, João F. | Pimentel, Gustavo D. | Inoue, Daniela S. | Panissa, Valéria L. G. | Monteiro, Paula Alves | Gerosa-Neto, José | Rossi, Fabrício E. | Caperuto, Erico C. | Cholewa, Jason M. | Zagatto, Alessandro M. | Lira, Fábio S. | Loureiro, Laís Monteiro Rodrigues | Reis, Caio Eduardo Gonçalves
PMCID: PMC5374629
8.  Proceedings of the Thirteenth International Society of Sports Nutrition (ISSN) Conference and Expo 
Ramaswamy, Lalitha | Velraja, Supriya | Escalante, Guillermo | Harvey, Phil | Alencar, Michelle | Haddock, Bryan | Harvey, Phil | Escalante, Guillermo | Alencar, Michelle | Haddock, Bryan | Durkalec-Michalski, Krzysztof | Jeszka, Jan | Zawieja, Bogna | Podgórski, Tomasz | Trussardi Fayh, Ana Paula | Okano, Alexandre Hideki | de Jesus Ferreira, Amanda Maria | Jäger, Ralf | Purpura, Martin | Harris, Roger C. | Krause, Molly M. | Lavanger, Kiley A. | Allen, Nina O. | Lieb, Allison E. | Mullen, Katie A. | Eckerson, Joan M. | Lavanger, Kiley A. | Krause, Molly M. | Allen, Nina O. | Lieb, Allison E. | Mullen, Katie A. | Eckerson, Joan M. | Morales, Elisa | Forsse, Jeffrey | Andre, Thomas | McKinley, Sarah | Hwang, Paul | Tinsley, Grant | Spillane, Mike | Grandjean, Peter | Willoughby, Darryn | Jagim, A. | Wright, G. | Kisiolek, J. | Meinking, M. | Ochsenwald, J. | Andre, M. | Jones, M. T. | Oliver, J. M. | Ferreira, Victor Araújo | de Souza, Daniel Costa | dos Santos, Victor Oliveira Albuquerque | Browne, Rodrigo Alberto Vieira | Costa, Eduardo Caldas | Fayh, Ana Paula Trussardi | Mathews, Suresh T. | Bishop, Haley D. | Bowen, Clara R. | Liang, Yishan | West, Emily A. | Rogers, Rebecca R. | Marshall, Mallory R. | Petrella, John K. | Holland, A. Maleah | Kephart, Wesley C. | Mumford, Petey W. | Mobley, C. Brooks | Lowery, Ryan P. | Wilson, Jacob M. | Roberts, Michael D. | Trexler, Eric T. | Hirsch, Katie R. | Campbell, Bill I. | Mock, Meredith G. | Smith-Ryan, Abbie E. | Zemek, Kate | Johnston, Carol | Mobley, C. Brooks | Mumford, Petey W. | Pascoe, David D. | Lockwood, Christopher M. | Miller, Michael E. | Roberts, Michael D. | Sanders, Gabriel J. | Peveler, Willard | Warning, Brooke | Peacock, Corey A. | Kephart, Wesley C. | Mumford, Petey W. | Lowery, Ryan P. | Roberts, Michael D. | Wilson, Jacob M. | Sandler, David | Ojalvo, Sara Perez | Komorowski, James | Campbell, Bill I. | Aguilar, Danielle | Vargas, Andres | Conlin, Laurin | Sanders, Amey | Fink-Irizarry, Paola | Norton, Layne | Perry, Ross | McCallum, Ryley | Wynn, Matthew R. | Lenton, Jack | Campbell, Bill I. | Gai, Chris | Donelson, Seth | Best, Shiva | Bove, Daniel | Couvillion, Kaylee | Dolan, Jeff | Xing, Dante | Chernesky, Kyshia | Pawela, Michael | Toledo, Andres D. | Jimenez, Rachel | Rabideau, M. | Walker, A. | Pellegrino, J. | Hofacker, M. | McFadden, B. | Conway, S. | Ordway, C. | Sanders, D. | Monaco, R. | Fragala, M. S. | Arent, S. M. | Stone, Jason D. | Kreutzer, Andreas | Oliver, Jonathan M. | Kisiolek, Jacob | Jagim, Andrew R. | Hofacker, M. | Walker, A. | Pellegrino, J. | Rabideau, M. | McFadden, B. | Conway, S. | Sanders, D. | Ordway, C. | Monaco, R. | Fragala, M. S. | Arent, S. M. | Tok, Ozlem | Pellegrino, Joseph K. | Walker, Alan J. | Sanders, David J. | McFadden, Bridget A. | Rabideau, Meaghan M. | Conway, Sean P. | Ordway, Chris E. | Bello, Marissa | Hofacker, Morgan L. | Mackowski, Nick S. | Poyssick, Anthony J. | Capone, Eddie | Monaco, Robert M. | Fragala, Maren S. | Arent, Shawn M. | Mumford, Petey W. | Holland, A. Maleah | Kephart, Wesley C. | Lowery, Ryan P. | Mobley, C. Brooks | Patel, Romil K. | Newton, Annie | Beck, Darren T. | Roberts, Michael D. | Wilson, Jacob M. | Young, Kaelin C. | Silver, Tobin | Ellerbroek, Anya | Buehn, Richard | Vargas, Leo | Tamayo, Armando | Peacock, Corey | Antonio, Jose | Ellerbroek, Anya | Silver, Tobin | Buehn, Richard | Vargas, Leo | Tamayo, Armando | Peacock, Corey | Antonio, Jose | Pollock, Adam | Ellerbroek, Anya | Silver, Tobin | Peacock, Corey | Antonio, Jose | Kreutzer, A. | Zavala, P. | Fleming, S. | Jones, M. | Oliver, J. M. | Jagim, A. | Haun, Cody T. | Mumford, Petey W. | Hyde, Parker N. | Fairman, Ciaran M. | Kephart, Wesley C. | Beck, Darren T. | Moon, Jordan R. | Roberts, Michael D. | Kendall, Kristina L. | Young, Kaelin C. | Hudson, Geoffrey M. | Hannings, Tara | Sprow, Kyle | DiPietro, Loretta | Kalman, Doug | Ojalvo, Sara Perez | Komorowski, James | Zavala, P. | Fleming, S. | Jones, M. | Oliver, J. | Jagim, A. | Wallace, Brian | Bergstrom, Haley | Wallace, Kelly | Monsalves-Alvarez, Matias | Oyharçabal, Sebastian | Espinoza, Victoria | VanDusseldorp, Trisha A. | Escobar, Kurt A. | Johnson, Kelly E. | Cole, Nathan | Moriarty, Terence | Stratton, Matthew | Endito, Marvin R. | Mermier, Christine M. | Kerksick, Chad M. | Romero, Matthew A. | Mobley, C. Brooks | Linden, Melissa | Meers, Grace Margaret-Eleanor | Rector, R. Scott | Roberts, Michael D. | Gills, Joshua L | Lu, Hocheng | Parker, Kimberly | Dobbins, Chris | Guillory, Joshua N. | Romer, Braden | Szymanski, David | Glenn, Jordan | Newmire, Daniel E. | Rivas, Eric | Deemer, Sarah E. | Wildman, Robert | Ben-Ezra, Victor | Kerksick, C. | Gieske, B. | Stecker, R. | Smith, C. | Witherbee, K. | Lane, Michael T. | Byrd, M. Travis | Bell, Zachary | Frith, Emily | Lane, Lauren M. C. | Lane, Michael T. | Byrd, M. Travis | Bell, Zachary | Frith, Emily | Lane, Lauren M. C. | Peacock, Corey A. | Silver, Tobin A. | Colas, Megan | Mena, Mauricio | Rodriguez, Winter | Sanders, Gabriel J. | Antonio, Jose | Vansickle, Andrea | DiFiore, Brittany | Stepp, Stephanie | Slack, Grant | Smith, Bridget | Ruffner, Kayla | Mendel, Ronald | Lowery, Lonnie | Hirsch, Katie R. | Mock, Meredith G. | Blue, Malia M. N. | Trexler, Eric T. | Roelofs, Erica J. | Smith-Ryan, Abbie E. | Conlin, Laurin | Aguilar, Danielle | Campbell, Bill I. | Norton, Layne | Coles, Katie | Trexler, Eric T. | Martinez, Nic | Joy, Jordan M. | Vogel, Roxanne M. | Hoover, Thomas H. | Broughton, K. Shane | Dalton, R. | Sowinski, R. | Grubic, T. | Collins, P. B. | Colletta, A. | Reyes, A. | Sanchez, B. | Kozehchain, M. | Jung, Y. P. | Rasmussen, C. | Murano, P. | Earnest, C. P. | Greenwood, M. | Kreider, R. B. | Grubic, T. | Dalton, R. | Sowinski, R. | Collins, P. B. | Colletta, A. | Reyes, A. | Sanchez, B. | Kozehchain, M. | Jung, Y. P. | Rasmussen, C. | Murano, P. | Earnest, C. P. | Greenwood, M. | Kreider, R. B. | Sowinski, R. | Dalton, R. | Grubic, T. | Collins, P. B. | Colletta, A. | Reyes, A. | Sanchez, B. | Kozehchain, M. | Jung, Y. P. | Rasmussen, C. | Murano, P. | Earnest, C. P. | Greenwood, M. | Kreider, R. B. | Durkalec-Michalski, Krzysztof | Jeszka, Jan | Podgórski, Tomasz | Kerksick, C. | Gieske, B. | Stecker, R. | Smith, C. | Witherbee, K. | Urbina, Stacie | Santos, Emily | Villa, Katelyn | Olivencia, Alyssa | Bennett, Haley | Lara, Marissa | Foster, Cliffa | Wilborn, Colin | Taylor, Lem | Cholewa, Jason M | Hewins, Amy | Gallo, Samantha | Micensky, Ashley | de Angelis, Christian | Carney, Christopher | Campbell, Bill | Conlin, Laurin | Norton, Layne | Rossi, Fabricio | Koozehchian, M. S. | Collins, P. B. | Sowinski, R. | Grubic, T. | Dalton, R. | O’Connor, A. | Shin, S. Y. | Jung, Y. Peter | Sanchez, B. K. | Coletta, A. | Cho, M. | Reyes, A. | Rasmussen, C. | Earnest, C. P. | Murano, P. S. | Greenwood, M. | Kreider, R. B.
Table of contents
P1 Impact of antioxidant-enriched nutrient bar supplementation on the serum antioxidant markers and physical fitness components of track and field athletes
Lalitha Ramaswamy, Supriya Velraja
P2 The effects of phosphatidic acid supplementation on fitness levels in resistance trained women
Guillermo Escalante, Phil Harvey, Michelle Alencar, Bryan Haddock
P3 The effects of phosphatidic acid supplementation on cardiovascular risk factors in resistance trained men
Phil Harvey, Guillermo Escalante, Michelle Alencar, Bryan Haddock
P4 The efficacy of sodium bicarbonate supplementation on physical capacity and selected biochemical markers in elite wrestlers
Krzysztof Durkalec-Michalski, Jan Jeszka, Bogna Zawieja, Tomasz Podgórski
P5 Effects of different nutritional strategies in hydration and physical performance in healthy well-trained males
Ana Paula Trussardi Fayh, Alexandre Hideki Okano, Amanda Maria de Jesus Ferreira
P6 Reduction of plasma creatine concentrations as an indicator of improved bioavailability
Ralf Jäger, Martin Purpura, Roger C Harris
P7 Effect of three different breakfast meals on energy intake and nutritional status in college-age women
Molly M. Krause, Kiley A. Lavanger, Nina O. Allen, Allison E. Lieb, Katie A. Mullen, Joan M. Eckerson
P8 Accuracy of the ASA24® Dietary Recall system for assessing actual dietary intake in normal weight college-age women.
Kiley A. Lavanger, Molly M. Krause, Nina O. Allen, Allison E. Lieb, Katie A. Mullen, Joan M. Eckerson
P9 β-aminoisobutyric acid does not regulate exercise induced UCP-3 expression in skeletal muscle
Elisa Morales, Jeffrey Forsse, Thomas Andre, Sarah McKinley, Paul Hwang, Grant Tinsley, Mike Spillane, Peter Grandjean, Darryn Willoughby
P10 The ability of collegiate football athletes to adhere to sport-specific nutritional recommendations
A. Jagim, G. Wright, J. Kisiolek, M. Meinking, J. Ochsenwald, M. Andre, M.T. Jones, J. M. Oliver
P11 A single session of low-volume high intensity interval exercise improves appetite regulation in overweight men
Victor Araújo Ferreira, Daniel Costa de Souza, Victor Oliveira Albuquerque dos Santos, Rodrigo Alberto Vieira Browne, Eduardo Caldas Costa, Ana Paula Trussardi Fayh
P12 Acute effects of oral peppermint oil ingestion on exercise performance in moderately-active college students
Suresh T. Mathews, Haley D. Bishop, Clara R. Bowen, Yishan Liang, Emily A. West, Rebecca R. Rogers, Mallory R. Marshall, John K. Petrella
P13 Associations in body fat and liver triglyceride content with serum health markers in sedentary and exercised rats fed a ketogenic diet, Western diet or standard chow over a 6-week period
A. Maleah Holland, Wesley C. Kephart, Petey W. Mumford, C. Brooks Mobley, Ryan P. Lowery, Jacob M. Wilson, Michael D. Roberts
P14 Physiological changes following competition in male and female physique athletes: A pilot study
Eric T. Trexler, Katie R. Hirsch, Bill I. Campbell, Meredith G. Mock, Abbie E. Smith-Ryan
P15 Relationship between cognition and hydration status in college students at a large Southwestern university
Kate Zemek, Carol Johnston
P16 Whey protein-derived exosomes increase protein synthesis in C2C12 myotubes
C. Brooks Mobley, Petey W. Mumford, David D. Pascoe, Christopher M. Lockwood, Michael E. Miller, Michael D. Roberts
P17 The effect of three different energy drinks on 1.5-mile running performance, oxygen consumption, and perceived exertion
Gabriel J. Sanders, Willard Peveler, Brooke Warning, Corey A. Peacock
P18 The Ketogenic diet improves rotarod performance in young and older rats
Wesley C. Kephart, Petey W. Mumford, Ryan P. Lowery, Michael D. Roberts, Jacob M. Wilson
P19 Absorption of bonded arginine silicate compared to individual arginine and silicon components
David Sandler, Sara Perez Ojalvo, James Komorowski
P20 Effects of a high (2.4 g/kg) vs. low/moderate (1.2 g/kg) protein intake on body composition in aspiring female physique athletes engaging in an 8-week resistance training program
Bill I. Campbell, Danielle Aguilar, Andres Vargas, Laurin Conlin, Amey Sanders, Paola Fink-Irizarry, Layne Norton, Ross Perry, Ryley McCallum, Matthew R. Wynn, Jack Lenton
P21 Effects of a high (2.4 g/kg) vs. low/moderate (1.2 g/kg) protein intake on maximal strength in aspiring female physique athletes engaging in an 8-week resistance training program
Bill I. Campbell, Chris Gai, Seth Donelson, Shiva Best, Daniel Bove, Kaylee Couvillion, Jeff Dolan, Dante Xing, Kyshia Chernesky, Michael Pawela, Andres D. Toledo, Rachel Jimenez
P22 Monitoring of female collegiate athletes over a competitive season reveals changes in nutritional biomarkers
M. Rabideau, A. Walker, J. Pellegrino, M. Hofacker, B. McFadden, S. Conway, C. Ordway, D. Sanders, R. Monaco, M. S. Fragala, S. M. Arent
P23 Comparison of prediction equations to indirect calorimetry in men and women athletes
Jason D. Stone, Andreas Kreutzer, Jonathan M. Oliver, Jacob Kisiolek, Andrew R. Jagim
P24 Regional variations in sweat-based electrolyte loss and changes in plasma electrolyte content in Division I female athletes over the course of a competitive season
M. Hofacker, A. Walker, J. Pellegrino, M. Rabideau, B. McFadden, S. Conway, D. Sanders, C. Ordway, R. Monaco, M. S. Fragala, S. M. Arent
P25 In-season changes in plasma amino acid levels in Division I NCAA female athletes
Ozlem Tok, Joseph K. Pellegrino, Alan J. Walker, David J. Sanders, Bridget A. McFadden, Meaghan M. Rabideau, Sean P. Conway, Chris E. Ordway, Marissa Bello, Morgan L. Hofacker, Nick S. Mackowski, Anthony J. Poyssick, Eddie Capone, Robert M. Monaco, Maren S. Fragala, Shawn M. Arent
P26 Effects of a ketogenic diet with exercise on serum markers of bone metabolism, IGF-1 and femoral bone mass in rats
Petey W. Mumford, A. Maleah Holland, Wesley C. Kephart, Ryan P. Lowery, C. Brooks Mobley, Romil K. Patel, Annie Newton, Darren T. Beck, Michael D. Roberts, Jacob M. Wilson, Kaelin C. Young
P27 Casein supplementation in trained men and women: morning versus evening
Tobin Silver, Anya Ellerbroek, Richard Buehn, Leo Vargas, Armando Tamayo, Corey Peacock, Jose Antonio
P28 A high protein diet has no harmful effects: a one-year crossover study in resistance-trained males
Anya Ellerbroek, Tobin Silver, Richard Buehn, Leo Vargas, Armando Tamayo, Corey Peacock, Jose Antonio
P29 SUP (Stand-up Paddling) athletes: nutritional intake and body composition
Adam Pollock, Anya Ellerbroek, Tobin Silver, Corey Peacock, Jose Antonio
P30 The effects of 8 weeks of colostrum and bio-active peptide supplementation on body composition in recreational male weight lifters
A. Kreutzer, P. Zavala, S. Fleming, M. Jones, J. M. Oliver, A. Jagim
P31 Effects of a Popular Women’s Thermogenic Supplement During an Energy-Restricted High Protein Diet on Changes in Body Composition and Clinical Safety Markers
Cody T. Haun, Petey W. Mumford, Parker N. Hyde, Ciaran M. Fairman, Wesley C. Kephart, Darren T. Beck, Jordan R. Moon, Michael D. Roberts, Kristina L. Kendall, Kaelin C. Young
P32 Three days of caffeine consumption following caffeine withdrawal yields small strength increase in knee flexors
Geoffrey M Hudson, Tara Hannings, Kyle Sprow, Loretta DiPietro
P33 Comparison of cellular nitric oxide production from various sports nutrition ingredients
Doug Kalman, Sara Perez Ojalvo, James Komorowski
P34 The effects of 8 weeks of bio-active peptide supplementation on training adaptations in recreational male weight lifters
P. Zavala, S. Fleming, M. Jones, J. Oliver, A. Jagim
P35 Effects of MusclePharm Assault BlackTM on lower extremity spinal excitability and postactivation potentiation: A pilot study
Brian Wallace, Haley Bergstrom, Kelly Wallace
P36 Effects of four weeks of Ketogenic Diet alone and combined with High intensity Interval Training or Continuous-Moderate intensity on body composition, lipid profile and physical performance on healthy males
Matias Monsalves-Alvarez, Sebastian Oyharçabal, Victoria Espinoza
P37 Effect of branched-chain amino acid supplementation on creatine kinase, muscular performance, and perceived muscle soreness following acute eccentric exercise
Trisha A. VanDusseldorp, Kurt A. Escobar, Kelly E. Johnson, Nathan Cole, Terence Moriarty, Matthew Stratton, Marvin R. Endito, Christine M. Mermier, Chad M. Kerksick
P38 Effects of endurance training on markers of ribosome biogenesis in rodents fed a high fat diet
Matthew A. Romero, C. Brooks Mobley, Melissa Linden, Grace Margaret-Eleanor Meers, R. Scott Rector, Michael D. Roberts
P39 The effects of acute citrulline-malate on lower-body isokinetic performance in recreationally active individuals
Joshua L Gills, Hocheng Lu, Kimberly Parker, Chris Dobbins, Joshua N Guillory, Braden Romer, David Szymanski, Jordan Glenn
P40 The effect pre-ingested L-isoleucine and L-leucine on blood glucose responses and glycemic hormones in healthy inactive adults: Preliminary data.
Daniel E. Newmire, Eric Rivas, Sarah E. Deemer, Robert Wildman, Victor Ben-Ezra
P41 Does protein and source impact substrate oxidation and energy expenditure during and after moderate intensity treadmill exercise?
C Kerksick, B Gieske, R Stecker, C Smith, K Witherbee
P42 Effects of a pre-workout supplement on peak power and power maintenance during lower and upper body testing
Michael T. Lane, M. Travis Byrd, Zachary Bell, Emily Frith, Lauren M.C. Lane
P43 Effects of a pre-workout supplement on peak power production during lower and upper body testing in college-age females
Michael T. Lane, M. Travis Byrd, Zachary Bell, Emily Frith, Lauren M.C. Lane
P44 A comparison of whey versus casein protein supplementation on resting metabolic rate and body composition: a pilot study
Corey A. Peacock, Tobin A. Silver, Megan Colas, Mauricio Mena, Winter Rodriguez, Gabriel J. Sanders, Jose Antonio
P45 A novel mixed-tocotrienol intervention enhances recovery after eccentric exercise: preliminary findings
Andrea Vansickle, Brittany DiFiore, Stephanie Stepp, Grant Slack, Bridget Smith, Kayla Ruffner, Ronald Mendel, Lonnie Lowery
P46 The effects of post-exercise ingestion of a high molecular weight glucose on cycle performance in female cyclists
Katie R. Hirsch, Meredith G. Mock, Malia M.N. Blue, Eric T. Trexler, Erica J. Roelofs, Abbie E. Smith-Ryan
P47 Inclusive vs. exclusive dieting and the effects on body composition in resistance trained individuals
Laurin Conlin, Danielle Aguilar, Bill I. Campbell, Layne Norton, Katie Coles, Eric T. Trexler, Nic Martinez
P48 A whey protein hydrolysate may positively augment resting metabolism compared to intact whey protein
Jordan M. Joy, Roxanne M. Vogel, Thomas H. Hoover, K. Shane Broughton
P49 Seven days of high and low dose creatine nitrate supplementation I: hepatorenal, glucose and muscle enzyme function
R Dalton, R Sowinski, T Grubic, PB Collins, A Colletta, A Reyes, B Sanchez, M Kozehchain, YP Jung, C Rasmussen, P Murano, CP Earnest, M Greenwood, RB Kreider
P50 Seven days of high and low dose creatine nitrate supplementation II: performance
T Grubic, R Dalton, R Sowinski, PB Collins, A Colletta, A Reyes, B Sanchez, M Kozehchain, YP Jung, C Rasmussen, P Murano, CP Earnest, M Greenwood, RB Kreider
P51 Seven days of high and low dose creatine nitrate supplementation III: hemodynamics
R Sowinski, R Dalton, T Grubic, PB Collins, A Colletta, A Reyes, B Sanchez, M Kozehchain, YP Jung, C Rasmussen, P Murano, CP Earnest, M Greenwood, RB Kreider
P52 The efficacy of a β-hydroxy-β-methylbutyrate supplementation on physical capacity, body composition and biochemical markers in highly-trained combat sports athletes
Krzysztof Durkalec-Michalski, Jan Jeszka, Tomasz Podgórski
P53 Does protein and source impact substrate oxidation and energy expenditure during and after moderate intensity treadmill exercise?
C Kerksick, B Gieske, R Stecker, C Smith, K Witherbee
P54 Effects of 30 days of Cleanse™ supplementation on measure of body composition, waist circumference, and markers of gastrointestinal distress in females
Stacie Urbina, Emily Santos, Katelyn Villa, Alyssa Olivencia, Haley Bennett, Marissa Lara, Cliffa Foster, Colin Wilborn, Lem Taylor
P55 The effects of moderate- versus high-load training on body composition, muscle growth, and performance in college aged females
Jason M Cholewa, Amy Hewins, Samantha Gallo, Ashley Micensky, Christian De Angelis, Christopher Carney, Bill Campbell, Laurin Conlin, Layne Norton, Fabricio Rossi
P56 Effect of a multi-ingredient preworkout supplement on cognitive function and perceptions of readiness to perform
MS Koozehchian, PB Collins, R Sowinski, T Grubic, R Dalton, A O’Connor, SY Shin, Y Peter Jung, BK Sanchez, A Coletta, M Cho, A Reyes, C Rasmussen, CP Earnest, PS Murano, M Greenwood, RB Kreider
PMCID: PMC5025820
9.  10th Anniversary of Acta stomatologica Croatica Online
ISSN 1846-0410 
PMCID: PMC4988821  PMID: 27688389
17.  International society of sports nutrition position stand: nutrient timing 
Position statement
The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained individuals on exercise performance and body composition. The following points summarize the position of the ISSN:Nutrient timing incorporates the use of methodical planning and eating of whole foods, fortified foods and dietary supplements. The timing of energy intake and the ratio of certain ingested macronutrients may enhance recovery and tissue repair, augment muscle protein synthesis (MPS), and improve mood states following high-volume or intense exercise.Endogenous glycogen stores are maximized by following a high-carbohydrate diet (8–12 g of carbohydrate/kg/day [g/kg/day]); moreover, these stores are depleted most by high volume exercise.If rapid restoration of glycogen is required (< 4 h of recovery time) then the following strategies should be considered:aggressive carbohydrate refeeding (1.2 g/kg/h) with a preference towards carbohydrate sources that have a high (> 70) glycemic indexthe addition of caffeine (3–8 mg/kg)combining carbohydrates (0.8 g/kg/h) with protein (0.2–0.4 g/kg/h) Extended (> 60 min) bouts of high intensity (> 70% VO2max) exercise challenge fuel supply and fluid regulation, thus carbohydrate should be consumed at a rate of ~30–60 g of carbohydrate/h in a 6–8% carbohydrate-electrolyte solution (6–12 fluid ounces) every 10–15 min throughout the entire exercise bout, particularly in those exercise bouts that span beyond 70 min. When carbohydrate delivery is inadequate, adding protein may help increase performance, ameliorate muscle damage, promote euglycemia and facilitate glycogen re-synthesis.Carbohydrate ingestion throughout resistance exercise (e.g., 3–6 sets of 8–12 repetition maximum [RM] using multiple exercises targeting all major muscle groups) has been shown to promote euglycemia and higher glycogen stores. Consuming carbohydrate solely or in combination with protein during resistance exercise increases muscle glycogen stores, ameliorates muscle damage, and facilitates greater acute and chronic training adaptations.Meeting the total daily intake of protein, preferably with evenly spaced protein feedings (approximately every 3 h during the day), should be viewed as a primary area of emphasis for exercising individuals.Ingestion of essential amino acids (EAA; approximately 10 g)either in free form or as part of a protein bolus of approximately 20–40 g has been shown to maximally stimulate muscle protein synthesis (MPS).Pre- and/or post-exercise nutritional interventions (carbohydrate + protein or protein alone) may operate as an effective strategy to support increases in strength and improvements in body composition. However, the size and timing of a pre-exercise meal may impact the extent to which post-exercise protein feeding is required.Post-exercise ingestion (immediately to 2-h post) of high-quality protein sources stimulates robust increases in MPS.In non-exercising scenarios, changing the frequency of meals has shown limited impact on weight loss and body composition, with stronger evidence to indicate meal frequency can favorably improve appetite and satiety. More research is needed to determine the influence of combining an exercise program with altered meal frequencies on weight loss and body composition with preliminary research indicating a potential benefit.Ingesting a 20–40 g protein dose (0.25–0.40 g/kg body mass/dose) of a high-quality source every three to 4 h appears to most favorably affect MPS rates when compared to other dietary patterns and is associated with improved body composition and performance outcomes.Consuming casein protein (~ 30–40 g) prior to sleep can acutely increase MPS and metabolic rate throughout the night without influencing lipolysis.
PMCID: PMC5596471  PMID: 28919842
Position stand; Exercise; Nutrition; Timing; Macronutrients; Performance; Micronutrients; Nutrients
18.  Turkish Publications in Science Citation Index and Citation Index-Expanded Indexed Journals in the Field of Anaesthesiology: A Bibliographic Analysis 
Our study aimed to assess Turkish publications in Science Citation Index (SCI) and Science Citation Index Expanded (SCI-E) indexed journals in the field of ‘anaesthesiology’.
Journals related to ‘anaesthesiology’ in the Science Citation Index-Expanded database of ‘Thomson Reuter Web of Science’ were searched. The search engine of Institute for Scientific Information (ISI) Web of Science (WoS) was used in the advanced mode by typing ‘IS=ISSN number’ to identify publications in the journal. By typing ‘IS=ISSN number AND CU=Turkey’, Turkish papers on anaesthesiology were found. If Turkish and non-Turkish authors had collaborated, the article was included in the search when the corresponding author had provided a Turkey-based address. The catalogue information and statistics were used to determine Turkish publications as the percentage of total publications and the annual mean number of Turkish publications. In WoS, ‘SU=anesthesiology’ was used to determine the number, country, year and topic distributions of publications from 1975 to date and within the last 10 years. The citation numbers and h-indices were determined based on the country for publications within the last 10 years.
From 1975 to the early 2000s Turkey was 20th in the list of countries with highest number of publications on anaesthesiology, however in the last 10 years Turkey moved up to 18th place. Its mean citation number has been 4.64, and it remains the 2nd lowest country pertaining to citations among the 22 countries with the most number of publications. According to the percentage of publications in the field of anaesthesiology, the journals with highest rate of Turkish publications were Revista Brasileira de Anestesiologia, European Journal of Anaesthesiology and Journal of Anesthesia.
In the field of anaesthesiology, the highest number of articles from Turkey was published in Revista Brasileira de Anestesiologia, European Journal of Anaesthesiology and Journal of Anesthesia. The mean citation number from these publications was 4.64.
PMCID: PMC5367721  PMID: 28377837
Anaesthesiology; Science Citation Index; Science Citation Index Expanded; Turkey
19.  International society of sports nutrition position stand: diets and body composition 
Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature regarding the effects of diet types (macronutrient composition; eating styles) and their influence on body composition. The ISSN has concluded the following. 1) There is a multitude of diet types and eating styles, whereby numerous subtypes fall under each major dietary archetype. 2) All body composition assessment methods have strengths and limitations. 3) Diets primarily focused on fat loss are driven by a sustained caloric deficit. The higher the baseline body fat level, the more aggressively the caloric deficit may be imposed. Slower rates of weight loss can better preserve lean mass (LM) in leaner subjects. 4) Diets focused primarily on accruing LM are driven by a sustained caloric surplus to facilitate anabolic processes and support increasing resistance-training demands. The composition and magnitude of the surplus, as well as training status of the subjects can influence the nature of the gains. 5) A wide range of dietary approaches (low-fat to low-carbohydrate/ketogenic, and all points between) can be similarly effective for improving body composition. 6) Increasing dietary protein to levels significantly beyond current recommendations for athletic populations may result in improved body composition. Higher protein intakes (2.3–3.1 g/kg FFM) may be required to maximize muscle retention in lean, resistance-trained subjects under hypocaloric conditions. Emerging research on very high protein intakes (>3 g/kg) has demonstrated that the known thermic, satiating, and LM-preserving effects of dietary protein might be amplified in resistance-training subjects. 7) The collective body of intermittent caloric restriction research demonstrates no significant advantage over daily caloric restriction for improving body composition. 8) The long-term success of a diet depends upon compliance and suppression or circumvention of mitigating factors such as adaptive thermogenesis. 9) There is a paucity of research on women and older populations, as well as a wide range of untapped permutations of feeding frequency and macronutrient distribution at various energetic balances combined with training. Behavioral and lifestyle modification strategies are still poorly researched areas of weight management.
PMCID: PMC5470183
20.  International Society of Sports Nutrition position stand: energy drinks 
Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature on the safety and efficacy of the use of energy drinks (ED) or energy shots (ES). The ISSN has concluded the following. 1. Although ED and ES contain a number of nutrients that are purported to affect mental and/or physical performance, the primary ergogenic nutrients in most ED and ES appear to be carbohydrate and/or caffeine. 2. The ergogenic value of caffeine on mental and physical performance has been well-established but the potential additive benefits of other nutrients contained in ED and ES remains to be determined. 3. Consuming ED 10-60 minutes before exercise can improve mental focus, alertness, anaerobic performance, and/or endurance performance. 4. Many ED and ES contain numerous ingredients; these products in particular merit further study to demonstrate their safety and potential effects on physical and mental performance. 5. There is some limited evidence that consumption of low-calorie ED during training and/or weight loss trials may provide ergogenic benefit and/or promote a small amount of additional fat loss. However, ingestion of higher calorie ED may promote weight gain if the energy intake from consumption of ED is not carefully considered as part of the total daily energy intake. 6. Athletes should consider the impact of ingesting high glycemic load carbohydrates on metabolic health, blood glucose and insulin levels, as well as the effects of caffeine and other stimulants on motor skill performance. 7. Children and adolescents should only consider use of ED or ES with parental approval after consideration of the amount of carbohydrate, caffeine, and other nutrients contained in the ED or ES and a thorough understanding of the potential side effects. 8. Indiscriminant use of ED or ES, especially if more than one serving per day is consumed, may lead to adverse events and harmful side effects. 9. Diabetics and individuals with pre-existing cardiovascular, metabolic, hepatorenal, and neurologic disease who are taking medications that may be affected by high glycemic load foods, caffeine, and/or other stimulants should avoid use of ED and/or ES unless approved by their physician.
PMCID: PMC3538552  PMID: 23281794
21.  International society of sports nutrition position stand: Beta-Alanine 
Position statement
The International Society of Sports Nutrition (ISSN) provides an objective and critical review of the mechanisms and use of beta-alanine supplementation. Based on the current available literature, the conclusions of the ISSN are as follows: 1) Four weeks of beta-alanine supplementation (4–6 g daily) significantly augments muscle carnosine concentrations, thereby acting as an intracellular pH buffer; 2) Beta-alanine supplementation currently appears to be safe in healthy populations at recommended doses; 3) The only reported side effect is paraesthesia (tingling), but studies indicate this can be attenuated by using divided lower doses (1.6 g) or using a sustained-release formula; 4) Daily supplementation with 4 to 6 g of beta-alanine for at least 2 to 4 weeks has been shown to improve exercise performance, with more pronounced effects in open end-point tasks/time trials lasting 1 to 4 min in duration; 5) Beta-alanine attenuates neuromuscular fatigue, particularly in older subjects, and preliminary evidence indicates that beta-alanine may improve tactical performance; 6) Combining beta-alanine with other single or multi-ingredient supplements may be advantageous when supplementation of beta-alanine is high enough (4–6 g daily) and long enough (minimum 4 weeks); 7) More research is needed to determine the effects of beta-alanine on strength, endurance performance beyond 25 min in duration, and other health-related benefits associated with carnosine.
PMCID: PMC4501114  PMID: 26175657
22.  International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB) 
Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature on the use of beta-hydroxy-beta-methylbutyrate (HMB) as a nutritional supplement. The ISSN has concluded the following. 1. HMB can be used to enhance recovery by attenuating exercise induced skeletal muscle damage in trained and untrained populations. 2. If consuming HMB, an athlete will benefit from consuming the supplement in close proximity to their workout. 3. HMB appears to be most effective when consumed for 2 weeks prior to an exercise bout. 4. Thirty-eight mg·kg·BM-1 daily of HMB has been demonstrated to enhance skeletal muscle hypertrophy, strength, and power in untrained and trained populations when the appropriate exercise prescription is utilized. 5. Currently, two forms of HMB have been used: Calcium HMB (HMB-Ca) and a free acid form of HMB (HMB-FA). HMB-FA may increase plasma absorption and retention of HMB to a greater extent than HMB-CA. However, research with HMB-FA is in its infancy, and there is not enough research to support whether one form is superior. 6. HMB has been demonstrated to increase LBM and functionality in elderly, sedentary populations. 7. HMB ingestion in conjunction with a structured exercise program may result in greater declines in fat mass (FM). 8. HMB’s mechanisms of action include an inhibition and increase of proteolysis and protein synthesis, respectively. 9. Chronic consumption of HMB is safe in both young and old populations.
PMCID: PMC3568064  PMID: 23374455
23.  GE – Into the Future 
PMCID: PMC5580127
ISSN, International Standard Serial Number; COPE, Committee on Publication Ethics; DOAJ, Directory of Open Access Journals; WAME, World Associaton of Medical Editors; OASPA, Open Access Scholarly Publishers Association; EQUATOR, Enhancing the QUAlity and Transparency Of health Research; ICMJE, International Committee of Medical Journal Editors
24.  Single-dose Toxicity of Guseonwangdo-go Glucose 5% Intravenous Injection in a Rat Model 
Journal of Pharmacopuncture  2015;18(3):57-62.
The purpose of this study was to examine the single-dose intravenous toxicity of Guseonwangdo-go glucose 5% pharmacopuncture (GWG5).
Forty Sprague-Dawley rats were divided into four groups of five males and five females per group: an intravenous (IV) injection of 1.0 mL of normal saline solution per animal was administered to the control group; IV injections of 0.1, 0.5, and 1.0 mL of GWG5 per animal were administered to the experimental groups (G: 0.1, G: 0.5, and G: 1.0). Observation of clinical signs and body weight measurements were carried out for 14 days following the injections. At the end of the observation period, hematological, biochemical, and histopathological tests, as well as necropsy examinations, were performed on the injected parts.
No mortalities or adverse clinical signs were observed in any of the groups. The body weights of all groups continuously increased. In the hematological and the biochemical tests, females in G-0.1 had minimal changes, but those changes were not dose dependent. On necropsy examination, no abnormalities were observed. In the histopathological test, focal inflammatory cell infiltrations were observed in two female rats, one in the control group and one in G-1.0. Also, one female rat in the control group had an epidermis crust. These changes were concluded to have been caused by the insertion of the needle into a vein.
The above findings suggest that the lethal dose of GWG5 administered via IV injection is more than 1.0 mL per animal in both male and female rats. Further studies are needed to establish more detailed evidence of its toxicity.
PMCID: PMC4573808  PMID: 26389002
Guseonwangdo-go glucose 5%;  herbal medicine;  intravenous;  pharmacopuncture;  toxicity testISSN
25.  In this issue 
Shanghai Archives of Psychiatry  2015;27(6):328-330.
A full-text Chinese
A full-text Chinese translation of this article will be available at on April 25, 2016.
PMCID: PMC4858503

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