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Volume 5(Suppl 8);  2011
Introduction
Cell Based Technologies: Abstracts of the 22nd ESACT Meeting 2011 in Vienna
Hansjörg Hauser
BMC Proc. 2011; 5(Suppl 8): I1. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-I1
PMCID:
PMC3284911
Full Text PDF–161K
Meeting Abstracts
Highly efficient, chemically defined and fully scalable biphasic production of vaccine viruses
Ingo Jordan, Volker Sandig
BMC Proc. 2011; 5(Suppl 8): O1. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O1
PMCID:
PMC3284961
Full Text PDF–243K
Improvement of cell freezing technologies: towards a fully closed process
Aurore Polès-Lahille, Brigitte Lafuente, Virginie Perrier, David Balbuena, Didier Peyret
BMC Proc. 2011; 5(Suppl 8): P1. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P1
PMCID:
PMC3284919
Full Text PDF–302K
Recombinant antibody mixtures; optimization of cell line generation and single-batch manufacturing processes
Søren K Rasmussen, Lars S Nielsen, Christian Müller, Thomas Bouquin, Henrik Næsted, Nina T Mønster, Frank Nygaard, Dietmar Weilguny, Torben P Frandsen, Anne B Tolstrup
BMC Proc. 2011; 5(Suppl 8): O2. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O2
PMCID:
PMC3285016
Full Text PDF–336K
Disposable bioreactors: from process development to production
Aurore Polès-Lahille, Celine Richard, Sandrine Fisch, David Pedelaborde, Sandy Gerby, Nora Kadi, Virginie Perrier, Robert Trieau, David Balbuena, Laure Valognes, Didier Peyret
BMC Proc. 2011; 5(Suppl 8): P2. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P2
PMCID:
PMC3284894
Full Text PDF–264K
Cell-based medicinal products and the development of GMP-compliant processes and manufacturing
Luca Romagnoli, Ilaria Giuntini, Marta Galgano, Chiara Crosta, Luigi Cavenaghi, Maria Luisa Nolli
BMC Proc. 2011; 5(Suppl 8): O3. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O3
PMCID:
PMC3284923
Full Text PDF–169K
Neuroprotective activity of a new erythropoietin formulation with increased penetration in the central nervous system
Marina Etcheverrigaray, Natalia Ceaglio, Mónica Mattio, Marcos Oggero, Ignacio Amadeo, Guillermina Forno, Norma Perotti, Ricardo Kratje
BMC Proc. 2011; 5(Suppl 8): P3. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P3
PMCID:
PMC3284997
Full Text PDF–228K
Biosynthetic pathway deflection – a new cell line engineering approach
Hans Henning von Horsten, Thomas Rose, Volker Sandig
BMC Proc. 2011; 5(Suppl 8): O4. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O4
PMCID:
PMC3284884
Full Text PDF–227K
New reporter cell clones to determine the biological activity of human type I interferons
Milagros Bürgi, Claudio Prieto, Marcos Oggero, Mariela Bollati-Fogolín, Marina Etcheverrigaray, Ricardo Kratje
BMC Proc. 2011; 5(Suppl 8): P4. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P4
PMCID:
PMC3284889
Full Text PDF–224K
Fluorescence-based tools to improve biopharmaceutical process development
Tiago M Duarte, Manuel JT Carrondo, Paula M Alves, Ana P Teixeira
BMC Proc. 2011; 5(Suppl 8): O5. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O5
PMCID:
PMC3284984
Full Text PDF–274K
Analytical techniques for characterization of raw materials in cell culture media
Chandana Sharma, Barry Drew, Kevin Head, Rani Pusuluri, Matthew V Caple
BMC Proc. 2011; 5(Suppl 8): P5. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P5
PMCID:
PMC3284981
Abstract Full Text PDF–263K
Towards rational engineering of cells: Recombinant gene expression in defined chromosomal loci
Kristina Nehlsen, Leonor da Gama-Norton, Roland Schucht, Hansjörg Hauser, Dagmar Wirth
BMC Proc. 2011; 5(Suppl 8): O6. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O6
PMCID:
PMC3284949
Full Text PDF–198K
Next-generation sequencing of the CHO cell transcriptome
Jennifer Becker, Christina Timmermann, Tobias Jakobi, Oliver Rupp, Rafael Szczepanowski, Matthias Hackl, Alexander Goesmann, Andreas Tauch, Nicole Borth, Johannes Grillari, Alfred Pühler, Thomas Noll, Karina Brinkrolf
BMC Proc. 2011; 5(Suppl 8): P6. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P6
PMCID:
PMC3284962
Full Text PDF–247K
Human hair follicle equivalents in vitro for transplantation and chip-based substance testing
R Horland, G Lindner, I Wagner, B Atac, S Hoffmann, M Gruchow, F Sonntag, U Klotzbach, R Lauster, U Marx
BMC Proc. 2011; 5(Suppl 8): O7. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O7
PMCID:
PMC3284944
Full Text PDF–239K
A strategy to obtain recombinant cell lines with high expression levels. Lentiviral vector-mediated transgenesis
Claudio Prieto, Diego Fontana, Marina Etcheverrigaray, Ricardo Kratje
BMC Proc. 2011; 5(Suppl 8): P7. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P7
PMCID:
PMC3284990
Full Text PDF–239K
Chromosome identification and its application in Chinese hamster ovary cells
Yihua Cao, Shuichi Kimura, Joon-young Park, Miyuki Yamatani, Kohsuke Honda, Hisao Ohtake, Takeshi Omasa
BMC Proc. 2011; 5(Suppl 8): O8. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O8
PMCID:
PMC3285028
Full Text PDF–406K
In-situ cell density monitoring and apoptosis detection in adherent Vero cell bioreactor cultures
Emma Petiot, Amal El-Wajgali, Geoffrey Esteban, Cécile Gény, Hervé Pinton, Annie Marc
BMC Proc. 2011; 5(Suppl 8): P8. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P8
PMCID:
PMC3285005
Full Text PDF–263K
Development of an automated, multiwell plate based screening system for suspension cell culture
Sven Markert, Klaus Joeris
BMC Proc. 2011; 5(Suppl 8): O9. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O9
PMCID:
PMC3284979
Full Text PDF–378K
Does earlier use of productivity enhancers during cell line selection lead to the identification of more productive cell lines?
Alison J Porter, Atul Mohindra, Juana Maria Porter, Andrew J Racher
BMC Proc. 2011; 5(Suppl 8): P9. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P9
PMCID:
PMC3284934
Full Text PDF–206K
Utilization of multifrequency permittivity measurements in addition to biomass monitoring
Christoph Heinrich, Tim Beckmann, Heino Büntemeyer, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): O10. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O10
PMCID:
PMC3284960
Full Text PDF–248K
Quantification of intracellular nucleotide sugars and formulation of a mathematical model for prediction of their metabolism
Ioscani Jiménez del Val, Judit M Nagy, Cleo Kontoravdi
BMC Proc. 2011; 5(Suppl 8): P10. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P10
PMCID:
PMC3284938
Full Text PDF–351K
ATF4 over-expression increased IgG1 productivity in Chinese hamster ovary cells
Ahmad M Haredy, Akitoshi Nishizawa, Kohsuke Honda, Tomoshi Ohya, Hisao Ohtake, Takeshi Omasa
BMC Proc. 2011; 5(Suppl 8): O11. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O11
PMCID:
PMC3284932
Full Text PDF–188K
Design and simulation of a controller system for metabolic shift regulation in mammalian cells
Damián Baeza, Ziomara P Gerdtzen, Cristian J Salgado
BMC Proc. 2011; 5(Suppl 8): P11. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P11
PMCID:
PMC3285004
Full Text PDF–300K
Characterization of novel pneumatic mixing for single-use bioreactor application
Brian Lee, David Fang, Matthew Croughan, Manuel Carrondo, Sang-Hoon Paik
BMC Proc. 2011; 5(Suppl 8): O12. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O12
PMCID:
PMC3284966
Full Text PDF–268K
The way to a design space for an animal cell culture process according to Quality by Design (QbD)
Robert Puskeiler, Jan Kreuzmann, Caroline Schuster, Katharina Didzus, Nicole Bartsch, Christian Hakemeyer, Heike Schmidt, Melanie Jacobs, Stefan Wolf
BMC Proc. 2011; 5(Suppl 8): P12. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P12
PMCID:
PMC3284890
Full Text PDF–324K
Enhanced protein synthesis and secretion using a rational signal-peptide library approach as a tailored tool
Beate Stern, Asta Optun, Melanie Liesenfeld, Christine Gey, Markus Gräfe, Ian F Pryme
BMC Proc. 2011; 5(Suppl 8): O13. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O13
PMCID:
PMC3284986
Full Text PDF–303K
Improvement of stem cell performance by supplementation with metabolic enhancers
Abi M Abitorabi, Christopher Wilcox
BMC Proc. 2011; 5(Suppl 8): P13. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P13
PMCID:
PMC3284996
Full Text PDF–284K
High-capacity assay to quantify the clonal heterogeneity in potency of mesenchymal stem cells
Kim C O’Connor, Katie C Russell, Donald G Phinney, Michelle R Lacey, Bonnie L Barrilleaux, Kristin E Meyertholen
BMC Proc. 2011; 5(Suppl 8): O14. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-O14
PMCID:
PMC3284945
Full Text PDF–177K
Use of Micro Bioreactor systems to streamline cell line evaluation and upstream process development for monoclonal antibody production
Steve R C Warr, Jai Patel, Rongzan Ho, Katy V Newell
BMC Proc. 2011; 5(Suppl 8): P14. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P14
PMCID:
PMC3284950
Full Text PDF–272K
Cell line selection using the Duetz Microflask system
Steve R C Warr, Sharon L White, Yuen-Ting Chim, Jai Patel, Hella Bosteels
BMC Proc. 2011; 5(Suppl 8): P15. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P15
PMCID:
PMC3284958
Full Text PDF–304K
Evaluation of an online biomass probe to monitor cell growth and cell death
Angelo Perani, Benjamin Gloria, Dongmao Wang, Anne-Sophie Buffier, Olivier Berteau, Geoffrey Esteban, Fiona E Smyth, Andrew M Scott
BMC Proc. 2011; 5(Suppl 8): P16. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P16
PMCID:
PMC3284924
Full Text PDF–208K
Impact on product quality of high productive GS-CHO cell lines
Angelo Perani, Benjamin Gloria, Dongmao Wang, Roger Murphy, Harjit Khangura Singh, Fiona E Smyth, Andrew M Scott
BMC Proc. 2011; 5(Suppl 8): P17. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P17
PMCID:
PMC3284987
Full Text PDF–260K
Anti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles
Sanetaka Shirahata, Takeki Hamasaki, Keisuke Haramaki, Takuro Nakamura, Masumi Abe, Hanxu Yan, Tomoya Kinjo, Noboru Nakamichi, Shigeru Kabayama, Kiichiro Teruya
BMC Proc. 2011; 5(Suppl 8): P18. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P18
PMCID:
PMC3284969
Full Text PDF–330K
Metabolic enhancers: a new paradigm in cell culture media optimization
Abi M Abitorabi, Christopher Wilcox
BMC Proc. 2011; 5(Suppl 8): P19. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P19
PMCID:
PMC3284953
Full Text PDF–254K
Neuroprotective effects of 3,5-di-o-caffeoylquinic acid in vitro and in vivo
Junkyu Han, Hiroko Isoda
BMC Proc. 2011; 5(Suppl 8): P20. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P20
PMCID:
PMC3285002
Full Text PDF–240K
Improvement of insulin resistance by Cyanidin 3-glucoside, anthocyanin from black beans through the up-regulation of GLUT4 gene expression
Tetsuya Inaguma, Junkyu Han, Hiroko Isoda
BMC Proc. 2011; 5(Suppl 8): P21. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P21
PMCID:
PMC3284935
Full Text PDF–192K
Engineering CHO cell growth by stable manipulation of miRNA expression
Noëlia Sanchez, Nga Lao, Clair Gallagher, Martin Clynes, Niall Barron
BMC Proc. 2011; 5(Suppl 8): P22. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P22
PMCID:
PMC3284937
Full Text PDF–246K
Expression of recombinant human coagulation factors VII (rFVII) and IX (rFIX) in various cell types, glycosylation analysis, and pharmacokinetic comparison
Ernst Böhm, Michael Dockal, Michael Graninger, Meinhard Hasslacher, Martin Kaliwoda, Christian Konetschny, Artur Mitterer, Eva-Maria Muchitsch, Manfred Reiter, Friedrich Scheiflinger
BMC Proc. 2011; 5(Suppl 8): P23. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P23
PMCID:
PMC3284992
Full Text PDF–349K
Complex medium supplements optimized for the reduction of animal-derived components in vaccine production media
James F Babcock, Karen A Benedict, Amanda L Perlman
BMC Proc. 2011; 5(Suppl 8): P24. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P24
PMCID:
PMC3285019
Full Text PDF–240K
Application of complex and chemically-defined medium supplements toward cell line specific performance enhancement of biopharmaceutical production systems
James F Babcock, Karen A Benedict, Amanda L Perlman
BMC Proc. 2011; 5(Suppl 8): P25. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P25
PMCID:
PMC3284951
Full Text PDF–331K
A comparison of performance enhancing synergy among ultrafiltered yeast extracts and recombinant human serum albumin in CHO-K1 cells
James F Babcock, Karen A Benedict, Amanda L Perlman
BMC Proc. 2011; 5(Suppl 8): P26. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P26
PMCID:
PMC3284920
Full Text PDF–340K
Targeted metabolomics for bioprocessing
Denise Sonntag, Francesca M Scandurra, Torben Friedrich, Michael Urban, Klaus M Weinberger
BMC Proc. 2011; 5(Suppl 8): P27. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P27
PMCID:
PMC3284902
Full Text PDF–230K
Toolbox approach for fast generation of stable CHO production cell lines from different hosts
Susanne Seitz, Henning von Horsten, Thomas Rose, Volker Sandig, Karsten Winkler
BMC Proc. 2011; 5(Suppl 8): P28. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P28
PMCID:
PMC3284931
Full Text PDF–248K
Growth characterization of CHO DP-12 cell lines with different high passage histories
Christoph Heinrich, Timo Wolf, Christina Kropp, Stefan Northoff, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P29. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P29
PMCID:
PMC3284905
Full Text PDF–261K
Utilization of multifrequency permittivity measurements in addition to biomass monitoring
Christoph Heinrich, Tim Beckmann, Heino Büntemeyer, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P30. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P30
PMCID:
PMC3284943
Full Text PDF–212K
CHO cell lines generated by PiggyBac transposition
Mattia Matasci, Virginie Bachmann, Lucia Baldi, David L Hacker, Maria De Jesus, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P31. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P31
PMCID:
PMC3284968
Full Text PDF–243K
Transposon mediated co-integration and co-expression of transgenes in CHO-DG44 cells
Sowmya Balasubramanian, Mattia Matasci, Lucia Baldi, David L Hacker, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P32. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P32
PMCID:
PMC3284971
Full Text PDF–257K
The use of filler DNA for improved transfection and reduced DNA needs in transient gene expression with CHO and HEK cells
Divor Kiseljak, Yashas Rajendra, Sagar S Manoli, Lucia Baldi, David L Hacker, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P33. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P33
PMCID:
PMC3285026
Full Text PDF–233K
Rapid recombinant protein production from pools of transposon-generated CHO cells
Mattia Matasci, Virginie Bachmann, Lucia Baldi, David L Hacker, Maria De Jesus, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P34. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P34
PMCID:
PMC3285008
Full Text PDF–319K
Influence of glutamine on transient and stable recombinant protein production in CHO and HEK-293 cells
Yashas Rajendra, Divor Kiseljak, Lucia Baldi, David L Hacker, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P35. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P35
PMCID:
PMC3284955
Full Text PDF–232K
kLa as a predictor for probe-independent mammalian cell bioprocesses in orbitally shaken bioreactors
Stéphanie Tissot, Dominique T Monteil, Lucia Baldi, David L Hacker, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P36. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P36
PMCID:
PMC3397689
Full Text PDF–274K
Transient transfection of insect Sf-9 cells in TubeSpin® bioreactor 50 tubes
Xiao Shen, Patrik O Michel, Qiuling Xie, David L Hacker, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P37. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P37
PMCID:
PMC3284885
Full Text PDF–251K
Transient gene expression with CHO cells in conditioned medium: a study using TubeSpin® bioreactors
João Pereira, Yashas Rajendra, Lucia Baldi, David L Hacker, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P38. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P38
PMCID:
PMC3284980
Full Text PDF–354K
Hydrodynamic stress in orbitally shaken bioreactors
Stéphanie Tissot, Martino Reclari, Samuel Quinodoz, Matthieu Dreyer, Dominique T Monteil, Lucia Baldi, David L Hacker, Mohamed Farhat, Marco Discacciati, Alfio Quarteroni, Florian M Wurm
BMC Proc. 2011; 5(Suppl 8): P39. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P39
PMCID:
PMC3284983
Full Text PDF–235K
A platform fed-batch process for various CEMAX® producer cell lines
Benedikt Greulich, Marika Poppe, Henry Woischnig, Karlheinz Landauer, Andreas Herrmann
BMC Proc. 2011; 5(Suppl 8): P40. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P40
PMCID:
PMC3285027
Full Text PDF–237K
Development of a chemically defined CHO medium by engineering based on a feed solution
Karlheinz Landauer, Henry Woischnig, Natalie Hepp, Benedikt Greulich, Andreas Herrmann
BMC Proc. 2011; 5(Suppl 8): P41. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P41
PMCID:
PMC3284933
Full Text PDF–241K
Process development of ATROSAB, an anti TNFR1 Monoclonal Antibody: in three steps from research to GMP
Karlheinz Landauer, Cuneyt Unutmaz, Simon Egli, Verena Berger, Simone Lais, Timo Liebig, Daniel Steiner, Jo Maier, Ina Rostalski, Francois Forcellino, Andreas Herrmann
BMC Proc. 2011; 5(Suppl 8): P42. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P42
PMCID:
PMC3284948
Full Text PDF–238K
Cell line development using the SEFEX system
Benedikt Greulich, Verena Berger, Marika Poppe, Natalie Hepp, Karlheinz Landauer, Andreas Herrmann
BMC Proc. 2011; 5(Suppl 8): P43. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P43
PMCID:
PMC3284915
Full Text PDF–201K
Platform process for production of monoclonal antibodies for research purposes – improvement option
Joern Meidahl Petersen, Claus Kristensen
BMC Proc. 2011; 5(Suppl 8): P44. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P44
PMCID:
PMC3285018
Full Text PDF–277K
Development and validation of a protocol for cell line identification by MALDI-TOF MS
Guido Vogel, André Strauss, Bernard Jenni, Dominik Ziegler, Eric Dumermuth, Sylvie Antz, Claudia Bardouille, Beat Wipf, Christian Miscenic, Georg Schmid, Valentin Pflüger
BMC Proc. 2011; 5(Suppl 8): P45. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P45
PMCID:
PMC3284903
Full Text PDF–428K
DoE of fed-batch processes – model-based design and experimental evaluation
Onur Sercinoglu, Oscar Platas Barradas, Volker Sandig, An-Ping Zeng, Ralf Pörtner
BMC Proc. 2011; 5(Suppl 8): P46. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P46
PMCID:
PMC3284917
Full Text PDF–563K
Criteria for bioreactor comparison and operation standardisation during process development for mammalian cell culture
Oscar Platas Barradas, Uwe Jandt, Linh Da Minh Phan, Mario Villanueva, Alexander Rath, Udo Reichl, Eva Schräder, Sebastian Scholz, Thomas Noll, Volker Sandig, Ralf Pörtner, An-Ping Zeng
BMC Proc. 2011; 5(Suppl 8): P47. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P47
PMCID:
PMC3284907
Full Text PDF–347K
Cultivation strategies of a BA/F3 cell line for fundamental cell research
Martin Schaletzky, Oscar Platas Barradas, Henning Sievert, Stefan Balabanov, An-Ping Zeng, Ralf Pörtner
BMC Proc. 2011; 5(Suppl 8): P48. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P48
PMCID:
PMC3284926
Full Text PDF–316K
Physical methods for synchronization of a human production cell line
Oscar Platas Barradas, Uwe Jandt, Ralf Hass, Cornelia Kasper, Volker Sandig, Ralf Pörtner, An-Ping Zeng
BMC Proc. 2011; 5(Suppl 8): P49. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P49
PMCID:
PMC3284918
Full Text PDF–270K
Efficient production of recombinant IgG by the GLUT5 co-expression system
Yuichi Inoue, Aiko Inoue, Hiroharu Kawahara
BMC Proc. 2011; 5(Suppl 8): P50. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P50
PMCID:
PMC3284928
Full Text PDF–170K
Innovative animal component-free surface for the cultivation of human embryonic stem cells
Thomas Stelzer, Tina Marwood, Cindy Neeley
BMC Proc. 2011; 5(Suppl 8): P51. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P51
PMCID:
PMC3284994
Full Text PDF–471K
Avian cell line - Technology for large scale vaccine production
Barbara Kraus, Simone von Fircks, Simone Feigl, Sabrina M Koch, Daniel Fleischanderl, Katherine Terler, Mitra Dersch-Pourmojib, Christian Konetschny, Leopold Grillberger, Manfred Reiter
BMC Proc. 2011; 5(Suppl 8): P52. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P52
PMCID:
PMC3285011
Full Text PDF–347K
Towards human central nervous system in vitro models for preclinical research: strategies for 3D neural cell culture
Daniel Simão, Inês Costa, Margarida Serra, Johannes Schwarz, Catarina Brito, Paula M Alves
BMC Proc. 2011; 5(Suppl 8): P53. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P53
PMCID:
PMC3284959
Full Text PDF–258K
Evaluation of a disposable stirred tank bioreactor for cultivation of mammalian cells
Alexander Hähnel, Benjamin Pütz, Kai Iding, Tabea Niediek, Frank Gudermann, Dirk Lütkemeyer
BMC Proc. 2011; 5(Suppl 8): P54. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P54
PMCID:
PMC3284973
Full Text PDF–229K
Controlled expansion and differentiation of mesenchymal stem cells in a microcarrier based stirred bioreactor
Sébastien Sart, Abdelmounaim Errachid, Yves-Jacques Schneider, Spiros N Agathos
BMC Proc. 2011; 5(Suppl 8): P55. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P55
PMCID:
PMC3284925
Full Text PDF–490K
3D6 and 4B3: Recombinant expression of two anti-gp41 antibodies as dimeric and secretory IgA
David Reinhart, Robert Weik, Renate Kunert
BMC Proc. 2011; 5(Suppl 8): P56. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P56
PMCID:
PMC3285001
Full Text PDF–151K
Creating new opportunities in process control through radio frequency impedance spectroscopy
Daniel W Logan, John P Carvell, Matthew P H Lee
BMC Proc. 2011; 5(Suppl 8): P57. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P57
PMCID:
PMC3284947
Full Text PDF–240K
Applications of nanoparticels in molecular and cellular biology and cancer research
Katya Simeonova, Ganka Milanova
BMC Proc. 2011; 5(Suppl 8): P58. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P58
PMCID:
PMC3284999
Full Text PDF–265K
Measurement of sialic acid content on recombinant membrane proteins
Deniz Baycin-Hizal, Sunny Mai, Daniel Wolozny, Ilhan Akan, Noboru Tomiya, Karen Palter, Michael Betenbaugh
BMC Proc. 2011; 5(Suppl 8): P59. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P59
PMCID:
PMC3284941
Full Text PDF–258K
Influence of operating parameters of a settling-based perfusion process on expansion of VERO cells attached on microcarriers
Amal El Wajgali, Frantz Fournier, Eric Olmos, Cécile Gény, Hervé Pinton, Annie Marc
BMC Proc. 2011; 5(Suppl 8): P60. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P60
PMCID:
PMC3284916
Full Text PDF–182K
3D-Bioreactor culture of human hepatoma cell line HepG2 as a promising tool for in vitro substance testing
Christiane Goepfert, Wibke Scheurer, Susanne Rohn, Britta Rathjen, Stefanie Meyer, Anja Dittmann, Katharina Wiegandt, Rolf Janßen, Ralf Pörtner
BMC Proc. 2011; 5(Suppl 8): P61. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P61
PMCID:
PMC3284898
Full Text PDF–246K
“BioProzessTrainer” as training tool for design of experiments
Ralf Pörtner, Oscar Platas-Barradas, Janosh Gradkowski, Richa Gautam, Florian Kuhnen, Volker C Hass
BMC Proc. 2011; 5(Suppl 8): P62. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P62
PMCID:
PMC3284900
Full Text PDF–299K
ADCC potency assay: increased standardization with modified lymphocytes
Laurent Bretaudeau, Véronique Bonnaudet
BMC Proc. 2011; 5(Suppl 8): P63. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P63
PMCID:
PMC3285017
Full Text PDF–254K
Anti-idiotypic antibody Ab2/3H6 mimicking gp41: a potential HIV-1 vaccine?
Renate Kunert, Alexander Mader
BMC Proc. 2011; 5(Suppl 8): P64. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P64
PMCID:
PMC3285015
Full Text PDF–263K
Application of hydrocyclones for continuous cultivation of SP-2/0 cells in perfusion bioreactors: Effect of hydrocyclone operating pressure
Elsayed A Elsayed, Roland Wagner
BMC Proc. 2011; 5(Suppl 8): P65. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P65
PMCID:
PMC3285022
Full Text PDF–391K
Improving volumetric productivity of a stable human CAP cell line by bioprocess optimization
Ruth Essers, Helmut Kewes, Gudrun Schiedner
BMC Proc. 2011; 5(Suppl 8): P66. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P66
PMCID:
PMC3284939
Full Text PDF–260K
Development of a triculture based system for improved benefit/risk assessment in pharmacology and human food
Alexandra Bazes, Géraldine Nollevaux, Régis Coco, Aurélie Joly, Thérèse Sergent, Yves-Jacques Schneider
BMC Proc. 2011; 5(Suppl 8): P67. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P67
PMCID:
PMC3284952
Full Text PDF–363K
Daphnane diterpene hirsein B downregulates melanogenesis in B16 murine melanoma cells by cAMP pathway inhibition
Myra O Villareal, Junkyu Han, Kenjiro Ikuta, Hiroko Isoda
BMC Proc. 2011; 5(Suppl 8): P68. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P68
PMCID:
PMC3284930
Full Text PDF–189K
The neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles
Hanxu Yan, Taichi Kashiwaki, Takeki Hamasaki, Tomoya Kinjo, Kiichiro Teruya, Shigeru Kabayama, Sanetaka Shirahata
BMC Proc. 2011; 5(Suppl 8): P69. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P69
PMCID:
PMC3285010
Full Text PDF–245K
Development and fine-tuning of a scale down model for process characterization studies of a monoclonal antibody upstream production process
Mareike Harmsen, Jimmy Stofferis, Laetitia Malphettes
BMC Proc. 2011; 5(Suppl 8): P70. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P70
PMCID:
PMC3284957
Full Text PDF–141K
Insect cell lines and baculoviruses as effective biocontrol agents of forest pests
Guido F Caputo, Sardar S Sohi, Sharon V Hooey, Lawrence J Gringorten
BMC Proc. 2011; 5(Suppl 8): P71. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P71
PMCID:
PMC3284929
Full Text PDF–181K
Down-regulation of CD81 in human cells producing HCV-E1/E2 retroVLPs
Ana F Rodrigues, Miguel R Guerreiro, Rute Castro, Hélio A Tomás, Charlotte Dalba, David Klatzmann, Paula M Alves, Manuel J T Carrondo, Ana S Coroadinha
BMC Proc. 2011; 5(Suppl 8): P72. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P72
PMCID:
PMC3284910
Full Text PDF–202K
Evaluation of disposable filtration systems for harvesting high cell density fed batch processes
Antje Pegel, Friedemann Übele, Sven Reiser, Dethardt Müller, Gregor Dudziak
BMC Proc. 2011; 5(Suppl 8): P73. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P73
PMCID:
PMC3284946
Full Text PDF–279K
Osteogenic Differentiation of adipose mesenchymal stem cells with BMP-2 embedded microspheres in a rotating bed bioreactor
Stefanie Boehm, Yael Lupu, Marcelle Machluf, Cornelia Kasper
BMC Proc. 2011; 5(Suppl 8): P74. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P74
PMCID:
PMC3284921
Full Text PDF–264K
Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells
Nadine Kochanowski, Gaetan Siriez, Sarah Roosens, Laetitia Malphettes
BMC Proc. 2011; 5(Suppl 8): P75. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P75
PMCID:
PMC3285007
Full Text PDF–354K
In-situ microscopy and 2D fluorescence spectroscopy as online methods for monitoring CHO cells during cultivation
Sophia Bonk, Marko Sandor, Ferdinand Rüdinger, Bernd Tscheschke, Andreas Prediger, Alexander Babitzky, Dørte Solle, Sascha Beutel, Thomas Scheper
BMC Proc. 2011; 5(Suppl 8): P76. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P76
PMCID:
PMC3284995
Full Text PDF–314K
On-line and real time cell counting and viability determination for animal cell process monitoring by in situ microscopy
Philipp Wiedemann, Markus Worf, Hans B Wiegemann, Florian Egner, Christian Schwiebert, Jeff Wilkesman, Jean S Guez, Juan C Quintana, Diego Assanza, Hajo Suhr
BMC Proc. 2011; 5(Suppl 8): P77. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P77
PMCID:
PMC3284899
Full Text PDF–264K
Characterization of the human AGE1.HN cell line: a systems biology approach
Sebastian Scholz, Miriam Luebbecke, Alexander Rath, Eva Schraeder, Thomas Rose, Heino Büntemeyer, Thomas Scheper, Udo Reichl, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P78. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P78
PMCID:
PMC3285003
Full Text PDF–320K
Influence of the nickel-titanium alloy components on biological functions
Akiko Ogawa, Ryota Akatsuka, Hidekazu Tamauchi, Katsuya Hio, Hideyuki Kanematsu
BMC Proc. 2011; 5(Suppl 8): P79. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P79
PMCID:
PMC3284991
Full Text PDF–249K
Metabolomics - a useful tool for prediction of protein production and processing?
Jennifer Kronthaler, Timo Schmidberger, Christine Heel
BMC Proc. 2011; 5(Suppl 8): P80. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P80
PMCID:
PMC3284964
Full Text PDF–241K
Accelerating process development through analysis of cell metabolism
Dirk Müller, Florian Kirchner, Stefanie Mangin, Klaus Mauch
BMC Proc. 2011; 5(Suppl 8): P81. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P81
PMCID:
PMC3284963
Full Text PDF–226K
Evaluation of sampling and quenching procedures for the analysis of intracellular metabolites in CHO suspension cells
Judith Wahrheit, Jens Niklas, Elmar Heinzle
BMC Proc. 2011; 5(Suppl 8): P82. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P82
PMCID:
PMC3284895
Full Text PDF–179K
Increasing productivity of hybridoma cell lines by sorting by side scattering light
Daniel Landgrebe, Cornelia Kasper, Thomas Scheper
BMC Proc. 2011; 5(Suppl 8): P83. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P83
PMCID:
PMC3284912
Full Text PDF–249K
Compartmentation and channelling of metabolites in the human cell line AGE1.HN®
Jens Niklas, Volker Sandig, Elmar Heinzle
BMC Proc. 2011; 5(Suppl 8): P84. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P84
PMCID:
PMC3284896
Full Text PDF–152K
Producer vs. parental cell – metabolic changes and burden upon α1-antitrypsin production in AGE1.HN®
Jens Niklas, Christian Priesnitz, Volker Sandig, Thomas Rose, Elmar Heinzle
BMC Proc. 2011; 5(Suppl 8): P85. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P85
PMCID:
PMC3285021
Full Text PDF–425K
Analysis of the mitochondrial subproteome of the human cell line AGE1.HN – a contribution to a systems biology approach
Eva Schräder, Sebastian Scholz, Volker Sandig, Raimund Hoffrogge, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P86. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P86
PMCID:
PMC3284977
Full Text PDF–207K
Characterisation of cultivation of the human cell line AGE1.HN.AAT
Eva Schräder, Sebastian Scholz, Jens Niklas, Alexander Rath, Oscar Platas Barradas, Uwe Jandt, Volker Sandig, Thomas Rose, Ralf Pörtner, Udo Reichl, An-Ping Zeng, Elmar Heinzle, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P87. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P87
PMCID:
PMC3284914
Full Text PDF–226K
Strategies in umbilical cord-derived mesenchymal stem cells expansion: influence of oxygen, culture medium and cell separation
Antonina Lavrentieva, Tim Hatlapatka, Ramona Winkler, Ralf Hass, Cornelia Kasper
BMC Proc. 2011; 5(Suppl 8): P88. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P88
PMCID:
PMC3284967
Full Text PDF–231K
Abstract withdrawn
BMC Proc. 2011; 5(Suppl 8): P89. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P89
PMCID:
PMC3284922
Full Text PDF–156K
Abstract withdrawn
BMC Proc. 2011; 5(Suppl 8): P90. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P90
PMCID:
PMC3284956
Full Text PDF–156K
Discerning key parameters influencing high productivity and quality through recognition of patterns in process data
Huong Le, Marlene Castro-Melchor, Christian Hakemeyer, Christine Jung, Berthold Szperalski, George Karypis, Wei-Shou Hu
BMC Proc. 2011; 5(Suppl 8): P91. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P91
PMCID:
PMC3284936
Full Text PDF–252K
Proteomic and metabolomic characterization of CHO DP-12 cell lines with different high passage histories
Tim Beckmann, Tobias Thüte, Christoph Heinrich, Heino Büntemeyer, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P92. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P92
PMCID:
PMC3284888
Full Text PDF–183K
A method for metabolomic sampling of suspended animal cells using fast filtration
Martin Volmer, Julia Gettmann, Sebastian Scholz, Heino Büntemeyer, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P93. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P93
PMCID:
PMC3284989
Full Text PDF–318K
Analysis of glycolytic flux as a rapid screen to identify low lactate producing CHO cell lines with desirable monoclonal antibody yield and glycan profile
Rachel Legmann, Julie Melito, Ilana Belzer, David Ferrick
BMC Proc. 2011; 5(Suppl 8): P94. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P94
PMCID:
PMC3284893
Full Text PDF–506K
Influence of cell specific productivity on product quality
Ruchika Srivastava, Lavanya Rao, Kriti Shukla, Sunaina Prabhu, Saravanan Desan, Dinesh Baskar, Ankur Bhatnagar, Anuj Goel, Harish Iyer
BMC Proc. 2011; 5(Suppl 8): P95. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P95
PMCID:
PMC3285012
Full Text PDF–284K
A novel peptide to enhance recombinant BMP-2 production in mammalian cell cultures
Aileen J Zhou, Cameron ML Clokie, Sean AF Peel
BMC Proc. 2011; 5(Suppl 8): P96. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P96
PMCID:
PMC3285006
Full Text PDF–225K
Determination of intracellular antibody production, cell density, and viability of recombinant CHO-DG44 cells using the MACSQuant® Analyzer
Jörn Pluschke, Sandra Klausing, Annika Haseloff, Bernd Schröder, Tanno Hübel
BMC Proc. 2011; 5(Suppl 8): P97. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P97
PMCID:
PMC3284954
Full Text PDF–279K
Bioreactor cultivation of CHO DP-12 cells under sodium butyrate treatment – comparative transcriptome analysis with CHO cDNA microarrays
Sandra Klausing, Oliver Krämer, Thomas Noll
BMC Proc. 2011; 5(Suppl 8): P98. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P98
PMCID:
PMC3285020
Full Text PDF–257K
Characterization of chromatographic yeast extract fractions promoting CHO cell growth
Mathilde Mosser, Romain Kapel, Arnaud Aymes, Laurent-Michel Bonanno, Eric Olmos, Iris Besançon, Dominique Druaux, Isabelle Chevalot, Ivan Marc, Annie Marc
BMC Proc. 2011; 5(Suppl 8): P99. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P99
PMCID:
PMC3284998
Full Text PDF–214K
Study of expansion of porcine bone marrow mesenchymal stem cells on microcarriers using various operating conditions
Caroline Ferrari, Frédérique Balandras, Emmanuel Guedon, Eric Olmos, Nguyen Tran, Isabelle Chevalot, Annie Marc
BMC Proc. 2011; 5(Suppl 8): P100. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P100
PMCID:
PMC3284975
Full Text PDF–252K
Growth and death kinetics of CHO cells cultivated in continuous bioreactor at various agitation rates
Frédérique Balandras, Eric Olmos, Caroline Hecklau, Fabrice Blanchard, Emmanuel Guedon, Annie Marc
BMC Proc. 2011; 5(Suppl 8): P101. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P101
PMCID:
PMC3397688
Full Text PDF–285K
Increasing antibody yield and modulating final product quality using the FreedomTM CHO-STM production platform
Michelle Sabourin, Ying Huang, Prasad Dhulipala, Shannon Beatty, Jian Liu, Peter Slade, Shawn Barrett, Shue-Yuan Wang, Karsten Winkler, Susanne Seitz, Thomas Rose, Volker Sandig, Peggy Lio, Steve Gorfien, Laurie Donahue-Hjelle, Graziella Piras
BMC Proc. 2011; 5(Suppl 8): P102. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P102
PMCID:
PMC3284927
Full Text PDF–225K
Single use bioreactors for the clinical production of monoclonal antibodies – a study to analyze the performance of a CHO cell line and the quality of the produced monoclonal antibody
Sonja Diekmann, Constanze Dürr, Alexander Herrmann, Ingo Lindner, Daniela Jozic
BMC Proc. 2011; 5(Suppl 8): P103. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P103
PMCID:
PMC3284970
Full Text PDF–439K
Development of live cultural pandemic influenza vaccine Vector-Flu
Elena A Nechaeva, Tatyana Y Sen’kina, Alexander B Ryzhikov, Irina F Radaeva, Ol’ga G P’yankova, Natal’ya V Danil’chenko, Tatyana M Sviridenko, Marina P Bogryantzeva, Natal’ya V Gilina, Nikolay A Varaksin, Tatyana G Ryabicheva, Irina V Kiseleva, Larisa G Rudenko
BMC Proc. 2011; 5(Suppl 8): P104. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P104
PMCID:
PMC3284988
Full Text PDF–149K
Study of a recombinant CHO cell line producing a monoclonal antibody by ATF or TFF external filter perfusion in a WAVE Bioreactor™
Marie-Françoise Clincke, Carin Mölleryd, Ye Zhang, Eva Lindskog, Kieron Walsh, Véronique Chotteau
BMC Proc. 2011; 5(Suppl 8): P105. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P105
PMCID:
PMC3285023
Full Text PDF–293K
Utilizing Roche Cedex Bio analyzer for in process monitoring in biotech production
Dörthe Druhmann, Sabrina Reinhard, Felizitas Schwarz, Christina Schaaf, Katrin Greisl, Tim Nötzel
BMC Proc. 2011; 5(Suppl 8): P106. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P106
PMCID:
PMC3284906
Full Text PDF–379K
LDH-C can be differentially expressed during fermentation of CHO cells
Berthold Szperalski, Christine Jung, Zhixin Shao, Anne Kantardjieff, Wei-Shou Hu
BMC Proc. 2011; 5(Suppl 8): P107. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P107
PMCID:
PMC3284887
Abstract Full Text PDF–274K
Stem cell: from basic theoretical assumptions and mathematical concepts to the computational models
Katya Simeonova, Ganka Milanova
BMC Proc. 2011; 5(Suppl 8): P108. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P108
PMCID:
PMC3284897
Full Text PDF–251K
Comparison of the activity and pluripotency maintaining potential of human leukemia inhibitory factor (LIF) produced in E.coli and CHO cells
Claas Haake, Sophia Bonk, Jana Parsiegla, Magda Tomala, Komal Loya, Malte Sgodda, Tobias Cantz, Axel Schambach, Cornelia Kasper, Thomas Scheper
BMC Proc. 2011; 5(Suppl 8): P109. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P109
PMCID:
PMC3284965
Full Text PDF–246K
Disulphide bond reduction of a therapeutic monoclonal antibody during cell culture manufacturing operations
Brian Mullan, Bryan Dravis, Amareth Lim, Ambrose Clarke, Susan Janes, Pete Lambooy, Don Olson, Tomas O’Riordan, Bruce Ricart, Alexander G Tulloch
BMC Proc. 2011; 5(Suppl 8): P110. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P110
PMCID:
PMC3284901
Full Text PDF–255K
Preliminary evaluation of microcarrier culture for growth and monoclonal antibody production of CHO-K1 cells
M Elisa Rodrigues, Pedro Fernandes, A Rita Costa, Mariana Henriques, Joana Azeredo, Rosário Oliveira
BMC Proc. 2011; 5(Suppl 8): P111. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P111
PMCID:
PMC3285000
Full Text PDF–173K
Strategies for adaptation of mAb-producing CHO cells to serum-free medium
A Rita Costa, M Elisa Rodrigues, Mariana Henriques, Rosário Oliveira, Joana Azeredo
BMC Proc. 2011; 5(Suppl 8): P112. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P112
PMCID:
PMC3284978
Full Text PDF–171K
Impact of different influenza cultivation conditions on HA N-Glycosylation
Jana V Roedig, Erdmann Rapp, Yvonne Genzel, Udo Reichl
BMC Proc. 2011; 5(Suppl 8): P113. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P113
PMCID:
PMC3284982
Full Text PDF–299K
Effect of iron sources on the glycosylation macroheterogeneity of human recombinant IFN-γ produced by CHO cells during batch processes
Marie-Françoise Clincke, Emmanuel Guedon, Frances T Yen, Virginie Ogier, Jean-Louis Goergen
BMC Proc. 2011; 5(Suppl 8): P114. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P114
PMCID:
PMC3284886
Full Text PDF–200K
Characterization of metalloprotease and serine protease activities in batch CHO cell cultures: control of human recombinant IFN-γ proteolysis by addition of iron citrate
Marie-Françoise Clincke, Emmanuel Guedon, Frances T Yen, Virginie Ogier, Jean-Louis Goergen
BMC Proc. 2011; 5(Suppl 8): P115. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P115
PMCID:
PMC3285009
Full Text PDF–246K
Isolation of active peptides from plant hydrolysates that promote Vero cells growth in stirred cultures
Samia Rourou, Rym Hssiki, Héla Kallel
BMC Proc. 2011; 5(Suppl 8): P116. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P116
PMCID:
PMC3285025
Full Text PDF–262K
Comparison of different membrane supports for monolayer culture of bovine oviduct epithelial cells
Muhammad Z Tahir, Fabien George, Isabelle Donnay
BMC Proc. 2011; 5(Suppl 8): P117. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P117
PMCID:
PMC3284909
Full Text PDF–222K
Efficacy of an inactivated and adjuvanted “ZULVAC® 8 OVIS” vaccine produced using single-use bioreactors
Lídia Garcia, Helena Paradell, Mercedes Mouriño, Berta Alberca, Alicia Urniza, Ana Vila, Margarita Tarrats, Joan Plana-Durán
BMC Proc. 2011; 5(Suppl 8): P118. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P118
PMCID:
PMC3284908
Full Text PDF–344K
Engineering CHO cell metabolism for growth in galactose
Natalia E Jiménez, Camila A Wilkens, Ziomara P Gerdtzen
BMC Proc. 2011; 5(Suppl 8): P119. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P119
PMCID:
PMC3285024
Full Text PDF–244K
Engineering CHO cells for improved central carbon and energy metabolism
Camila A Wilkens, Ziomara P Gerdtzen
BMC Proc. 2011; 5(Suppl 8): P120. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P120
PMCID:
PMC3284891
Full Text PDF–313K
Mitogenic effect of sericin on mammalian cells
Wataru Sato, Ken Fukumoto, Kana Yanagihara, Masahiro Sasaki, Yoshihiro Kunitomi, Satoshi Terada
BMC Proc. 2011; 5(Suppl 8): P121. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P121
PMCID:
PMC3284913
Full Text PDF–360K
Challenges in scaling up a perfusion process
Vana Raja, Saravanan Desan, Ankur Bhatnagar, Anuj Goel, Harish Iyer
BMC Proc. 2011; 5(Suppl 8): P122. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P122
PMCID:
PMC3284882
Full Text PDF–256K
High cell density growth of High Five suspension cells in DO-controlled wave-mixed bioreactors
Teddy Beltrametti, Nicole C Bögli, Gerhard Greller, Regine Eibl, Dieter Eibl
BMC Proc. 2011; 5(Suppl 8): P123. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P123
PMCID:
PMC3284904
Full Text PDF–171K
Bag-based rapid and safe seed-train expansion method for Trichoplusia ni suspension cells
Nicole C Bögli, Christoph Ries, Irina Bauer, Thorsten Adams, Gerhard Greller, Regine Eibl, Dieter Eibl
BMC Proc. 2011; 5(Suppl 8): P124. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P124
PMCID:
PMC3284974
Full Text PDF–174K
On-line monitoring of the live cell concentration in bioreactors based on a rocking platform
John Carvell, Matt Lee
BMC Proc. 2011; 5(Suppl 8): P125. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P125
PMCID:
PMC3284892
Full Text PDF–242K
Optimization of HEK 293 cell growth by addition of non-animal derived components using design of experiments
Laura Cervera, Sonia Gutiérrez, Francesc Gòdia, María M Segura
BMC Proc. 2011; 5(Suppl 8): P126. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P126
PMCID:
PMC3284993
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Evaluation of three commercial kits for mycoplasma NAT assays: selection and quality improvement
Fabien Dorange, Frédérick Le Goff, Nicolas Dumey
BMC Proc. 2011; 5(Suppl 8): P127. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P127
PMCID:
PMC3284942
Full Text PDF–179K
Large pilot scale cultivation process study of adherent MDBK cells for porcine Influenza A virus propagation using a novel disposable stirred-tank bioreactor
Boris Hundt, Noreen Mölle, Sabine Stefaniak, Ralf Dürrwald, Joerg Weyand
BMC Proc. 2011; 5(Suppl 8): P128. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P128
PMCID:
PMC3284883
Full Text PDF–376K
Effect of influenza virus infection on key metabolic enzyme activities in MDCK cells
Robert Janke, Yvonne Genzel, Maria Wetzel, Udo Reichl
BMC Proc. 2011; 5(Suppl 8): P129. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P129
PMCID:
PMC3284985
Full Text PDF–397K
Novel human partner cell line for immortalisation of rare antigen-specific B cells in mAb development
Galina Kaseko, Marjorie Liu, Qiong Li, Tohsak Mahaworasilpa
BMC Proc. 2011; 5(Suppl 8): P130. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P130
PMCID:
PMC3284940
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Application of the novel and convenient IR/MAR gene amplification technology to the production of recombinant protein pharmaceuticals
Yoshio Araki, Chiemi Noguchi, Tetsuro Hamafuji, Hiroshi Nose, Daisuke Miki, Noriaki Shimizu
BMC Proc. 2011; 5(Suppl 8): P131. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P131
PMCID:
PMC3285013
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About making a CHO production cell line “research-friendly” by genetic engineering
Bernd Voedisch, Agnès Patoux, Jildou Sterkenburgh, Mirjam Buchs, Emily Barry, Cyril Allard, Sabine Geisse
BMC Proc. 2011; 5(Suppl 8): P132. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P132
PMCID:
PMC3284972
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CAP-T cell expression system: a novel rapid and versatile human cell expression system for fast and high yield transient protein expression
Jens Wölfel, Ruth Essers, Corinna Bialek, Sabine Hertel, Nadine Scholz-Neumann, Gudrun Schiedner
BMC Proc. 2011; 5(Suppl 8): P133. Published online 2011 November 22. doi: 10.1186/1753-6561-5-S8-P133
PMCID:
PMC3284976
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Production and purification of TGFb-1 in CHO-Cells
Estabraq Abdulkerim, Sabrina Baganz, Axel Schambach, Cornelia Kasper, Thomas Scheper
BMC Proc. 2011; 5(Suppl 8): P134. Published online 2011 December 16. doi: 10.1186/1753-6561-5-S8-P134
PMCID:
PMC3285014
Full Text PDF–682K
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