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Volume 11(6);  2009
Editorials
SAPHO syndrome: Is a range of pathogen-associated rheumatic diseases extended?
Alexander P Rozin
Arthritis Res Ther. 2009; 11(6): 131. Published online 2009 November 5. doi: 10.1186/ar2837
PMCID:
PMC3003498
Abstract Full Text PDF–56K
Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis?
Fons A van de Loo, Wim B van den Berg
Arthritis Res Ther. 2009; 11(6): 132. Published online 2009 November 6. doi: 10.1186/ar2835
PMCID:
PMC3003506
Abstract Full Text PDF–45K
TWEAK: a novel biomarker for lupus nephritis?
Neeraj Dhaun, David C Kluth
Arthritis Res Ther. 2009; 11(6): 133. Published online 2009 November 17. doi: 10.1186/ar2846
PMCID:
PMC3003535
Abstract Full Text PDF–47K
Rituximab treatment in rheumatoid arthritis: how does it work?
Maria JH Boumans, Paul P Tak
Arthritis Res Ther. 2009; 11(6): 134. Published online 2009 November 24. doi: 10.1186/ar2852
PMCID:
PMC3003538
Abstract Full Text PDF–43K
Microparticles as biomarkers in autoimmunity: from dust bin to center stage
David S Pisetsky
Arthritis Res Ther. 2009; 11(6): 135. Published online 2009 November 30. doi: 10.1186/ar2856
PMCID:
PMC3003533
Abstract Full Text PDF–45K
The 'RASor's' edge: Ras proteins and matrix destruction in arthritis
Adam C Schmucker, Constance E Brinckerhoff
Arthritis Res Ther. 2009; 11(6): 136. Published online 2009 December 11. doi: 10.1186/ar2840
PMCID:
PMC3003537
Abstract Full Text PDF–41K
The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis
Pierre Youinou, Chaim Putterman
Arthritis Res Ther. 2009; 11(6): 137. Published online 2009 December 11. doi: 10.1186/ar2869
PMCID:
PMC3003496
Abstract Full Text PDF–50K
Effective rheumatoid arthritis treatment requires comprehensive management strategies
Chad S Boomershine
Arthritis Res Ther. 2009; 11(6): 138. Published online 2009 December 21. doi: 10.1186/ar2872
PMCID:
PMC3003495
Abstract Full Text PDF–42K
Meeting Report
Kitasato Symposium 2009: New Prospects for Cytokine Inhibition
Gerd R Burmester, Peter E Lipsky, Thomas Dörner
Arthritis Res Ther. 2009; 11(6): 301. Published online 2009 December 23. doi: 10.1186/ar2857
PMCID:
PMC3003512
Abstract Full Text PDF–929K
Research Articles
Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators
Hyun-Mi Choi, Yeon-Ah Lee, Sang-Hoon Lee, Seung-Jae Hong, Dae-Hyun Hahm, Sang-Yun Choi, Hyung-In Yang, Myung Chul Yoo, Kyoung Soo Kim
Arthritis Res Ther. 2009; 11(6): R161. Published online 2009 November 2. doi: 10.1186/ar2844
PMCID:
PMC3003518
Abstract Full Text PDF–1.5M
Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression
Martha C Castaño Betancourt, Jacqueline C Van der Linden, Fernando Rivadeneira, Rianne M Rozendaal, Sita M Bierma Zeinstra, Harrie Weinans, Jan H Waarsing
Arthritis Res Ther. 2009; 11(6): R162. Published online 2009 November 2. doi: 10.1186/ar2845
PMCID:
PMC3003541
Abstract Full Text PDF–727K
ACR70-disease activity score remission achievement from switches between all the available biological agents in rheumatoid arthritis: a systematic review of the literature
Stefano Alivernini, Antonella Laria, Elisa Gremese, Angelo Zoli, Gianfranco Ferraccioli
Arthritis Res Ther. 2009; 11(6): R163. Published online 2009 November 3. doi: 10.1186/ar2848
PMCID:
PMC3003527
Abstract Full Text PDF–202K
Sinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapy
Ariane Leboime, Jean-Marie Berthelot, Yannick Allanore, Lama Khalil-Kallouche, Philippe Herman, Philippe Orcel, Frédéric Lioté
Arthritis Res Ther. 2009; 11(6): R164. Published online 2009 November 3. doi: 10.1186/ar2849
PMCID:
PMC3003503
Abstract Full Text PDF–752K
Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis
Constanze Csaki, Ali Mobasheri, Mehdi Shakibaei
Arthritis Res Ther. 2009; 11(6): R165. Published online 2009 November 4. doi: 10.1186/ar2850
PMCID:
PMC3003513
Abstract Full Text PDF–2.7M
Effect of small interference RNA (siRNA) for ADAMTS5 on intervertebral disc degeneration in the rabbit anular needle-puncture model
Shoji Seki, Yumiko Asanuma-Abe, Koichi Masuda, Yoshiharu Kawaguchi, Kunihiro Asanuma, Carol Muehleman, Akiko Iwai, Tomoatsu Kimura
Arthritis Res Ther. 2009; 11(6): R166. Published online 2009 November 4. doi: 10.1186/ar2851
PMCID:
PMC3003501
Abstract Full Text PDF–1.9M
Altered peptide ligands inhibit arthritis induced by glucose-6-phosphate isomerase peptide
Keiichi Iwanami, Isao Matsumoto, Yohei Yoshiga, Asuka Inoue, Yuya Kondo, Kayo Yamamoto, Yoko Tanaka, Reiko Minami, Taichi Hayashi, Daisuke Goto, Satoshi Ito, Yasuharu Nishimura, Takayuki Sumida
Arthritis Res Ther. 2009; 11(6): R167. Published online 2009 November 9. doi: 10.1186/ar2854
PMCID:
PMC3003534
Abstract Full Text PDF–1.5M
Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles
Srilakshmi M Sharma, Dongseok Choi, Stephen R Planck, Christina A Harrington, Carrie R Austin, Jinnell A Lewis, Tessa N Diebel, Tammy M Martin, Justine R Smith, James T Rosenbaum
Arthritis Res Ther. 2009; 11(6): R168. Published online 2009 November 9. doi: 10.1186/ar2855
PMCID:
PMC3003511
Abstract Full Text PDF–385K Supplementary Material
Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation
Stéphane Genevay, Axel Finckh, Françoise Mezin, Enrico Tessitore, Pierre-André Guerne
Arthritis Res Ther. 2009; 11(6): R169. Published online 2009 November 11. doi: 10.1186/ar2858
PMCID:
PMC3003509
Abstract Full Text PDF–341K
Rapid and sustained improvements in health-related quality of life, fatigue, and other patient-reported outcomes in rheumatoid arthritis patients treated with certolizumab pegol plus methotrexate over 1 year: results from the RAPID 1 randomized controlled trial
Vibeke Strand, Philip Mease, Gerd R Burmester, Enkeleida Nikaï, Geoffroy Coteur, Ronald van Vollenhoven, Bernard Combe, Edward C Keystone, Arthur Kavanaugh
Arthritis Res Ther. 2009; 11(6): R170. Published online 2009 November 12. doi: 10.1186/ar2859
PMCID:
PMC3003523
Abstract Full Text PDF–1001K
HLA-E gene polymorphism associates with ankylosing spondylitis in Sardinia
Fabiana Paladini, Francesca Belfiore, Elisa Cocco, Carlo Carcassi, Alberto Cauli, Alessandra Vacca, Maria Teresa Fiorillo, Alessandro Mathieu, Isabella Cascino, Rosa Sorrentino
Arthritis Res Ther. 2009; 11(6): R171. Published online 2009 November 13. doi: 10.1186/ar2860
PMCID:
PMC3003531
Abstract Full Text PDF–215K
Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury
Huina Zhang, Lin Wang, Jun Beom Park, Paul Park, Victor C Yang, Scott J Hollister, Frank La Marca, Chia-Ying Lin
Arthritis Res Ther. 2009; 11(6): R172. Published online 2009 November 13. doi: 10.1186/ar2861
PMCID:
PMC3003500
Abstract Full Text PDF–2.7M
Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications
Christopher G Wilson, Eric J Vanderploeg, Fengrong Zuo, John D Sandy, Marc E Levenston
Arthritis Res Ther. 2009; 11(6): R173. Published online 2009 November 17. doi: 10.1186/ar2862
PMCID:
PMC3003508
Abstract Full Text PDF–1.6M
Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid arthritis
Kazuhisa Nozawa, Maki Fujishiro, Mikiko Kawasaki, Hiroshi Kaneko, Kazuhisa Iwabuchi, Mitsuaki Yanagida, Fujihiko Suzuki, Keiji Miyazawa, Yoshinari Takasaki, Hideoki Ogawa, Kenji Takamori, Iwao Sekigawa
Arthritis Res Ther. 2009; 11(6): R174. Published online 2009 November 18. doi: 10.1186/ar2863
PMCID:
PMC3003536
Abstract Full Text PDF–674K
Detection of Chlamydia trachomatis-DNA in synovial fluid: evaluation of the sensitivity of different DNA extraction methods and amplification systems
Julia Freise, Iris Bernau, Sabine Meier, Henning Zeidler, Jens G Kuipers
Arthritis Res Ther. 2009; 11(6): R175. Published online 2009 November 21. doi: 10.1186/ar2864
PMCID:
PMC3003517
Abstract Full Text PDF–367K
CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production
Maurizio Cutolo, Stefano Soldano, Paola Montagna, Alberto Sulli, Bruno Seriolo, Barbara Villaggio, Pierfranco Triolo, Paolo Clerico, Lamberto Felli, Renata Brizzolara
Arthritis Res Ther. 2009; 11(6): R176. Published online 2009 November 23. doi: 10.1186/ar2865
PMCID:
PMC3003520
Abstract Full Text PDF–1.2M
Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study
Matthew L Mundwiler, Ling Mei, Carol J Landers, John D Reveille, Stephan Targan, Michael H Weisman
Arthritis Res Ther. 2009; 11(6): R177. Published online 2009 November 23. doi: 10.1186/ar2866
PMCID:
PMC3003540
Abstract Full Text PDF–273K
Infliximab concentration monitoring improves the control of disease activity in rheumatoid arthritis
Denis Mulleman, Jean-Camille Méric, Gilles Paintaud, Emilie Ducourau, Charlotte Magdelaine-Beuzelin, Jean-Pierre Valat, Philippe Goupille
Arthritis Res Ther. 2009; 11(6): R178. Published online 2009 November 25. doi: 10.1186/ar2867
PMCID:
PMC3003525
Abstract Full Text PDF–303K Supplementary Material
Safety of TNF-blocking agents in rheumatic patients with serology suggesting past hepatitis B state: results from a cohort of 21 patients
Caroline Charpin, Sandrine Guis, Philippe Colson, Patrick Borentain, Jean-Pierre Mattéi, Patrice Alcaraz, Nathalie Balandraud, Benoit Thomachot, Jean Roudier, René Gérolami
Arthritis Res Ther. 2009; 11(6): R179. Published online 2009 November 26. doi: 10.1186/ar2868
PMCID:
PMC3003507
Abstract Full Text PDF–133K
A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis
Wei Wei, Ling-Ling Zhang, Jian-Hua Xu, Feng Xiao, Chun-De Bao, Li-Qing Ni, Xing-Fu Li, Yu-Qing Wu, Ling-Yun Sun, Rong-Hua Zhang, Bao-Liang Sun, Sheng-Qian Xu, Shang Liu, Wei Zhang, Jie Shen, Hua-Xiang Liu, Ren-Cheng Wang
Arthritis Res Ther. 2009; 11(6): R180. Published online 2009 December 1. doi: 10.1186/ar2870
PMCID:
PMC3003530
Abstract Full Text PDF–294K
Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study
Miranda L Davies-Tuck, Fahad Hanna, Susan R Davis, Robin J Bell, Sonia L Davison, Anita E Wluka, Jenny Adams, Flavia M Cicuttini
Arthritis Res Ther. 2009; 11(6): R181. Published online 2009 December 4. doi: 10.1186/ar2873
PMCID:
PMC3003521
Abstract Full Text PDF–151K
Psychological correlates of self-reported functional limitation in patients with ankylosing spondylitis
Tamar F Brionez, Shervin Assassi, John D Reveille, Thomas J Learch, Laura Diekman, Michael M Ward, John C Davis, Jr, Michael H Weisman, Perry Nicassio
Arthritis Res Ther. 2009; 11(6): R182. Published online 2009 December 7. doi: 10.1186/ar2874
PMCID:
PMC3003522
Abstract Full Text PDF–152K
Comparative, double-blind, controlled study of intra-articular hyaluronic acid (Hyalubrix®) injections versus local anesthetic in osteoarthritis of the hip
Alberto Migliore, Umberto Massafra, Emanuele Bizzi, Francesca Vacca, Severino Martin-Martin, Mauro Granata, Andrea Alimonti, Sandro Tormenta
Arthritis Res Ther. 2009; 11(6): R183. Published online 2009 December 9. doi: 10.1186/ar2875
PMCID:
PMC3003515
Abstract Full Text PDF–248K
Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs
Helen E Gruber, Jane A Ingram, Gretchen L Hoelscher, Natalia Zinchenko, H James Norton, Edward N Hanley, Jr
Arthritis Res Ther. 2009; 11(6): R184. Published online 2009 December 9. doi: 10.1186/ar2876
PMCID:
PMC3003526
Abstract Full Text PDF–2.7M
A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis
Benoit Le Goff, Elise Soltner, Céline Charrier, Yves Maugars, Françoise Rédini, Dominique Heymann, Jean-Marie Berthelot
Arthritis Res Ther. 2009; 11(6): R185. Published online 2009 December 10. doi: 10.1186/ar2877
PMCID:
PMC3003529
Abstract Full Text PDF–1.1M
Predictors of the first cardiovascular event in patients with systemic lupus erythematosus - a prospective cohort study
Johanna Gustafsson, Iva Gunnarsson, Ola Börjesson, Susanne Pettersson, Sonia Möller, Guo-Zhong Fei, Kerstin Elvin, Julia F Simard, Lars-Olof Hansson, Ingrid E Lundberg, Anders Larsson, Elisabet Svenungsson
Arthritis Res Ther. 2009; 11(6): R186. Published online 2009 December 10. doi: 10.1186/ar2878
PMCID:
PMC3003532
Abstract Full Text PDF–185K
RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFα or anti-IL-1 therapies
Marina Stolina, Georg Schett, Denise Dwyer, Steven Vonderfecht, Scot Middleton, Diane Duryea, Efrain Pacheco, Gwyneth Van, Brad Bolon, Ulrich Feige, Debra Zack, Paul Kostenuik
Arthritis Res Ther. 2009; 11(6): R187. Published online 2009 December 11. doi: 10.1186/ar2879
PMCID:
PMC3003514
Abstract Full Text PDF–620K
Serum levels of autoantibodies against C-reactive protein correlate with renal disease activity and response to therapy in lupus nephritis
Christopher Sjöwall, Agneta Zickert, Thomas Skogh, Jonas Wetterö, Iva Gunnarsson
Arthritis Res Ther. 2009; 11(6): R188. Published online 2009 December 11. doi: 10.1186/ar2880
PMCID:
PMC3003497
Abstract Full Text PDF–501K
Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome
Jelle L Vosters, Hongen Yin, Nienke Roescher, Marc R Kok, Paul P Tak, John A Chiorini
Arthritis Res Ther. 2009; 11(6): R189. Published online 2009 December 14. doi: 10.1186/ar2888
PMCID:
PMC3003528
Abstract Full Text PDF–515K
Separating therapeutic efficacy from glucocorticoid side-effects in rodent arthritis using novel, liposomal delivery of dexamethasone phosphate: long-term suppression of arthritis facilitates interval treatment
Una Rauchhaus, Franz Werner Schwaiger, Steffen Panzner
Arthritis Res Ther. 2009; 11(6): R190. Published online 2009 December 15. doi: 10.1186/ar2889
PMCID:
PMC3003516
Abstract Full Text PDF–204K
Better assessment of physical function: item improvement is neglected but essential
Bonnie Bruce, James F Fries, Debbie Ambrosini, Bharathi Lingala, Barbara Gandek, Matthias Rose, John E Ware, Jr
Arthritis Res Ther. 2009; 11(6): R191. Published online 2009 December 16. doi: 10.1186/ar2890
PMCID:
PMC3003539
Abstract Full Text PDF–153K
Phytalgic®, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial
Alain Jacquet, Pierre-Olivier Girodet, Antoine Pariente, Karelle Forest, Laurent Mallet, Nicholas Moore
Arthritis Res Ther. 2009; 11(6): R192. Published online 2009 December 16. doi: 10.1186/ar2891
PMCID:
PMC3003499
Abstract Full Text PDF–178K
Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study
Fleur E van de Geijn, Manfred Wuhrer, Maurice HJ Selman, Sten P Willemsen, Yaël A de Man, André M Deelder, Johanna MW Hazes, Radboud JEM Dolhain
Arthritis Res Ther. 2009; 11(6): R193. Published online 2009 December 16. doi: 10.1186/ar2892
PMCID:
PMC3003510
Abstract Full Text PDF–814K
Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORγt in γδ T cells
Ferry Cornelissen, Adriana MC Mus, Patrick S Asmawidjaja, Jan Piet van Hamburg, Joel Tocker, Erik Lubberts
Arthritis Res Ther. 2009; 11(6): R194. Published online 2009 December 17. doi: 10.1186/ar2893
PMCID:
PMC3003524
Abstract Full Text PDF–1.0M Supplementary Material
Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis
Laure Delavallée, Luca Semerano, Eric Assier, Géraldine Vogel, Grégoire Vuagniaux, Marion Laborie, Daniel Zagury, Natacha Bessis, Marie-Christophe Boissier
Arthritis Res Ther. 2009; 11(6): R195. Published online 2009 December 23. doi: 10.1186/ar2897
PMCID:
PMC3003505
Abstract Full Text PDF–831K Supplementary Material
Reviews
Biomarkers as tools for improved diagnostic and therapeutic monitoring in systemic lupus erythematosis
Michael F Smith, Jr, Falk Hiepe, Thomas Dörner, Gerd Burmester
Arthritis Res Ther. 2009; 11(6): 255. Published online 2009 November 19. doi: 10.1186/ar2834
PMCID:
PMC3003542
Abstract Full Text PDF–72K
Utility of synovial biopsy
Stefan Vordenbäumen, Leo AB Joosten, Johannes Friemann, Matthias Schneider, Benedikt Ostendorf
Arthritis Res Ther. 2009; 11(6): 256. Published online 2009 November 23. doi: 10.1186/ar2847
PMCID:
PMC3003519
Abstract Full Text PDF–1.4M
Heterogeneity of human effector CD4+ T cells
Francesco Annunziato, Sergio Romagnani
Arthritis Res Ther. 2009; 11(6): 257. Published online 2009 December 9. doi: 10.1186/ar2843
PMCID:
PMC3003504
Abstract Full Text PDF–636K
Treatment of Lyme borreliosis
Hermann J Girschick, Henner Morbach, Dennis Tappe
Arthritis Res Ther. 2009; 11(6): 258. Published online 2009 December 17. doi: 10.1186/ar2853
PMCID:
PMC3003502
Abstract Full Text PDF–389K
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