AAPS PharmSci Volume 2(1); March 2000

Volume 2(1); March 2000

Articles

Pharmacokinetics of nevirapine and lamivudine in patients with HIV-1 infection

John P. Sabo, Michael J. Lamson, Gerhard Leitz, Chan-Loi Yong, Thomas R. MacGregor

AAPS PharmSci. 2000 March; 2(1): 1–8. Published online 2000 February 17. doi: 10.1208/ps020101

PMCID:: PMC2750996

Abstract Full Text PDF–253K

Molecular modeling of G-protein coupled receptor kinase 2: Docking and biochemical evaluation of inhibitors

Matthias U. Kassack, Petra Högger, Daniel A. Gschwend, Kimihiko Kameyama, Tatsuya Haga, Richard C. Graul, Wolfgang Sadée

AAPS PharmSci. 2000 March; 2(1): 9–21. Published online 2000 February 21. doi: 10.1208/ps020102

PMCID:: PMC2750997

Abstract Full Text PDF–395K

Maturation and growth of renal function: Dosing renally cleared drugs in children

William L. Hayton

AAPS PharmSci. 2000 March; 2(1): 22–28. Published online 2000 March 3. doi: 10.1208/ps020103

PMCID:: PMC2750998

Abstract Full Text PDF–477K

Pharmacogenomics: The promise of personalized medicine

Laviero Mancinelli, Maureen Cronin, Wolfgang Sadée

AAPS PharmSci. 2000 March; 2(1): 29–41. Published online 2000 March 7. doi: 10.1208/ps020104

PMCID:: PMC2750999

Abstract Full Text PDF–177K

Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides

Chimanlall Goolcharran, Andrew J. S. Jones, Ronald T. Borchardt

AAPS PharmSci. 2000 March; 2(1): 42–47. Published online 2000 March 17. doi: 10.1208/ps020105

PMCID:: PMC2751000

Abstract Full Text PDF–141K

Targeted prodrug design to optimize drug delivery

Hyo-Kyung Han, Gordon L. Amidon

AAPS PharmSci. 2000 March; 2(1): 48–58. Published online 2000 March 21. doi: 10.1208/ps020106

PMCID:: PMC2751001

Abstract Full Text PDF–222K

Synthesis and characterization of positively charged tPA as a prodrug using a heparin/protamine-based drug-delivery system

Jun F. Liang, Yong T. Li, Maureen E. Connell, Victor C. Yang

AAPS PharmSci. 2000 March; 2(1): 59–67. Published online 2000 March 21. doi: 10.1208/ps020107

PMCID:: PMC2751002

Abstract Full Text PDF–232K

Comparison of methods for analyzing kinetic data from mechanism-based enzyme inactivation: Application to nitric oxide synthase

Tristan S. Maurer, Ho-Leung Fung

AAPS PharmSci. 2000 March; 2(1): 68–77. Published online 2000 March 22. doi: 10.1208/ps020108

PMCID:: PMC2751003

Abstract Full Text PDF–418K

Comparative evaluation of the degree of indomethacin crystallinity by chemoinfometrical fourie-transformed near-infrared spectroscopy and conventional powder X-ray diffractiometry

Makoto Otsuka, Fumie Kato, Yoshihisa Matsuda

AAPS PharmSci. 2000 March; 2(1): 80–87. Published online 2000 March 23. doi: 10.1208/ps020109

PMCID:: PMC2751004

Abstract Full Text PDF–148K

Articles from AAPS PharmSci are provided here courtesy of
American Association of Pharmaceutical Scientists

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